Voprosy biokhimii mozga最新文献_第4页

[Changes in the ribonuclease activity of brain cell nuclei and mitochondria at different periods following removal of the superior cervical sympathetic ganglion]. [切除颈上交感神经节后不同时期脑细胞细胞核和线粒体核糖核酸酶活性的变化]。

Voprosy biokhimii mozga Pub Date : 1976-01-01

E E Mkheian, T D Karapetian

引用次数: 0

[Soluble cerebral metalloproteins. II. Superoxide dismutases of cerebral gray and white matter]. 可溶性脑金属蛋白。2脑灰质和白质的超氧化物歧化症。

Voprosy biokhimii mozga Pub Date : 1976-01-01

S G Sharoian, A A Shaldzhian, R M Nalbandian, G Kh Buniatian

引用次数: 0

[Molecular heterogeneity of rat brain and kidney glutamate dehydrogenase]. [大鼠脑和肾谷氨酸脱氢酶的分子异质性]。

Voprosy biokhimii mozga Pub Date : 1976-01-01

S G Avetisian, S G Movesian, G Kh Buniatian

引用次数: 0

[Molecular mechanisms of mediator secretion]. [介质分泌的分子机制]。

Voprosy biokhimii mozga Pub Date : 1976-01-01

R N Glebov, G N Kryzhanovskiĭ

{"title":"[Molecular mechanisms of mediator secretion].","authors":"R N Glebov, G N Kryzhanovskiĭ","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A review is presented discussing problems of transmitter localization in nerve endings, their replenishment in synaptic vesicles (SV), reuptake of transmitters and their degradation products from the synaptic cleft, the structural variations in the presynaptic membrane (pre-SM) during rest and excitation and the role of contractile proteins in the mechanism underlying transmitter secretion. A hypothesis is proposed about the universality of the mechanisms involved in transmitter release and utilization and the key role of the membrane ATP-ase system in these processes. During depolarization of the pre-SM the increase in membrane permeability is ascribed to the loosening of protein-lipid bonds and inhibition of ATP-ase activity involved in transport mechanisms. During depolarization the number of complementary contacts between SV and the pre-SM increase probably through the action of myosin-like and actin-like proteins localized on the SV and pre-SM, respectively. The release of transmitters and polypeptides is thought to be initiated by an increased concentration of Ca2+ in the synaptoplasm which induces contraction of the actomyosin-like complex. Changes in the Na-gradient brought about by the activity of Na, K-ATP-ase, are involved in the active reuptake of transmitters from the synaptic cleft. The newly-synthesized transmitters and those taken up from the synaptic cleft are stored in the SV by a Mg-ATP-ase dependent mechanism. Transmitters are stored in SV bound to acid polypeptides containing nucleotides. The presynaptic action of different neurotoxins is also discussed.</p>","PeriodicalId":76813,"journal":{"name":"Voprosy biokhimii mozga","volume":"11 ","pages":"171-96"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11295472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

[Effect of diethylstilbestrol and steroid hormones on glutaminase activity in the mitochondrial fraction of rat brain]. [己烯雌酚和类固醇激素对大鼠脑线粒体部分谷氨酰胺酶活性的影响]。

Voprosy biokhimii mozga Pub Date : 1976-01-01

K S Mikirtunova, R L Aĭrapetian, V S Oganesian, G Kh Buniatian

引用次数: 0

[Formation of ammonia from glutamic acid and ADP in purified mitochondria and nerve endings of rat cerebral cortex]. [纯化的大鼠大脑皮层线粒体和神经末梢中谷氨酸和ADP形成氨]。

Voprosy biokhimii mozga Pub Date : 1976-01-01

Zh A Paronian, G V Aprikian, G A Mkrtchian, S S Musaelian

引用次数: 0

[Peptide hydrolase activity of the soluble protein fractions of cattle and rabbit cerebral hemispheric gray and white matter]. [牛和兔大脑半球灰质和白质可溶性蛋白组分的肽水解酶活性]。

Voprosy biokhimii mozga Pub Date : 1976-01-01

G L Remeniuk, A G Grinenko, Ia V Belik