[Peptide hydrolase activity of the soluble protein fractions of cattle and rabbit cerebral hemispheric gray and white matter].

Abstract

The neutral peptide-hydrolase activity of the soluble protein fraction of homogenates of whole brain and white and grey matters of bovine and rabbit cerebral hemispheres are significantly reduced on dialysis against water. In the evaporated dialysate the enzymatic activity of the soluble protein fraction is completely recovered. The reduction of peptide hydrolase activity following dialysis is probably due to the decrease of ionic strengths. The peptide hydrolase system of bovine brain is less stable on storage than that of rabbit brain.