[Changes in the ribonuclease activity of brain cell nuclei and mitochondria at different periods following removal of the superior cervical sympathetic ganglion].

Abstract

A study of the changes in the ribonuclease activity of nuclei and mitochondria of rat brain cells following 1, 3, 7, 20 and 90 days after extirpation of the right superior cervical ganglion showed an increase of enzyme activity in nuclei from the first up to the 90-th day following removal of the ganglion. During the first three days after the operation enzyme activity is higher in nuclei obtained from the intact (left) side of the brain while later on enzyme activity is more pronounced in nuclei obtained from the right (sympathectomized) side of the brain. In mitochondria enzyme activity is depressed during the whole period studied after sympathectomy (90 days).