发布求助
文献互助 智能选刊 最新文献

Virchows Archiv. B, Cell pathology最新文献

筛选
英文 中文
Adaptive changes of rat liver cells induced by repeated intraperitoneal injections of d-galactosamine. III-Light- and electron-microscopic investigations of hepatocellular cytoplasmic changes. 反复腹腔注射d-半乳糖胺对大鼠肝细胞适应性的影响。肝细胞质改变的光镜和电镜检查。
Virchows Archiv. B, Cell pathology Pub Date : 1978-01-18 DOI: 10.1007/BF02889551
H K Koch, B Häberle, K Meinhardt, H Enzan, R Lesch
{"title":"Adaptive changes of rat liver cells induced by repeated intraperitoneal injections of d-galactosamine. III-Light- and electron-microscopic investigations of hepatocellular cytoplasmic changes.","authors":"H K Koch,&nbsp;B Häberle,&nbsp;K Meinhardt,&nbsp;H Enzan,&nbsp;R Lesch","doi":"10.1007/BF02889551","DOIUrl":"https://doi.org/10.1007/BF02889551","url":null,"abstract":"<p><p>In rats hepatocellular cytoplasmic changes after daily repeated D-galactosamine (GalN) intoxication--i.e. subacute GalN intoxication--were studied by light and electron microscopy. The number of GalN injections--and thus the days of survival--was between one and 30. The rats were killed six hours after the last GalN injection. Less degenerative changes were found after repeated GalN injections. An increased formation of atypical dense bodies (ADB), a temporary pronounced lipid accumulation and changes of the rough and smooth endoplasmic reticulum were prominent features of subacute GalN intoxication. The implications with respect to a modified GalN action in subacute GalN intoxication are discussed with special reference to biochemical data obtained in the same experimental model (Schuchhardt et al., 1977).</p>","PeriodicalId":76800,"journal":{"name":"Virchows Archiv. B, Cell pathology","volume":"26 3","pages":"233-47"},"PeriodicalIF":0.0,"publicationDate":"1978-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02889551","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11622910","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Number of nucleoli in Ehrlich tumor cells during interphase. 间期埃利希肿瘤细胞核仁数量。
Virchows Archiv. B, Cell pathology Pub Date : 1978-01-18 DOI: 10.1007/BF02889555
A Lepoint, R Bassleer
{"title":"Number of nucleoli in Ehrlich tumor cells during interphase.","authors":"A Lepoint,&nbsp;R Bassleer","doi":"10.1007/BF02889555","DOIUrl":"https://doi.org/10.1007/BF02889555","url":null,"abstract":"<p><p>Fractions of mouse Ehrlich ascites tumor cell populations with a high percentage of cell either in early or in late interphase were separated by centrifugation on ficoll gradients. Nucleoli were studied by light or electron microscopy in these cell subpopulations. It was shown that, in these cells, the number of nucleoli per nucleus does not vary significantly during interphase. This result is discussed and an anlysis of the relationships between the number and the volume of the nucleoli in these cells is present.</p>","PeriodicalId":76800,"journal":{"name":"Virchows Archiv. B, Cell pathology","volume":"26 3","pages":"267-73"},"PeriodicalIF":0.0,"publicationDate":"1978-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02889555","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11622912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Cell kinetics of mouse urinary bladder epithelium. III. A histologic and ultrastructural study of bladder epithelium during regeneration after a single dose of cyclophosphamide, with special reference to the mechanism by which polyploid cells are formed. 小鼠膀胱上皮细胞动力学。3单剂量环磷酰胺后膀胱上皮再生过程的组织学和超微结构研究，特别参考多倍体细胞形成的机制。
Virchows Archiv. B, Cell pathology Pub Date : 1978-01-18
T Farsund, E Dahl
{"title":"Cell kinetics of mouse urinary bladder epithelium. III. A histologic and ultrastructural study of bladder epithelium during regeneration after a single dose of cyclophosphamide, with special reference to the mechanism by which polyploid cells are formed.","authors":"T Farsund,&nbsp;E Dahl","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In order to see whether the polyploid cells lining the mouse urinary bladder are formed by nuclear fusion, such epithelium was studied under the light and electron microscope forty-eight hours after an injection of cyclophosphamide when the bladder epithelium regenerates with rapid formation of many diploid, tetraploid and octoploid cells. The probability of seing fusion, if it occurs, ought then to be high. Serial sections of many specimens from four mice revealed no signs of fusion. Thus we found no support for the theory that polyploid cells are formed by nuclear fusion.</p>","PeriodicalId":76800,"journal":{"name":"Virchows Archiv. B, Cell pathology","volume":"26 3","pages":"215-23"},"PeriodicalIF":0.0,"publicationDate":"1978-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11622908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Annulate lamellae in a malignant mesenchymal tumor. 恶性间充质瘤的环状片。
Virchows Archiv. B, Cell pathology Pub Date : 1978-01-18 DOI: 10.1007/BF02889553
J Bhawan, L Ceccacci, J Cranford
{"title":"Annulate lamellae in a malignant mesenchymal tumor.","authors":"J Bhawan,&nbsp;L Ceccacci,&nbsp;J Cranford","doi":"10.1007/BF02889553","DOIUrl":"https://doi.org/10.1007/BF02889553","url":null,"abstract":"<p><p>Intracytoplasmic membranous structures, known as annulate lamellae were seen in a malignant mesenchymal tumor. Close relationship with rough endoplasmic reticulum (ER) suggested their origin from ER.</p>","PeriodicalId":76800,"journal":{"name":"Virchows Archiv. B, Cell pathology","volume":"26 3","pages":"261-5"},"PeriodicalIF":0.0,"publicationDate":"1978-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02889553","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11622911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 9
Scanning and transmission electronmicroscopy of leukemic lymphoma cells without T- and B-cell surface markers. 无T细胞和b细胞表面标记物的白血病淋巴瘤细胞的扫描和透射电镜。
Virchows Archiv. B, Cell pathology Pub Date : 1978-01-18 DOI: 10.1007/BF02889550
T Shigematsu, T Nagasaki, M Kikuchi, K Kishida, M Miyoshi
{"title":"Scanning and transmission electronmicroscopy of leukemic lymphoma cells without T- and B-cell surface markers.","authors":"T Shigematsu,&nbsp;T Nagasaki,&nbsp;M Kikuchi,&nbsp;K Kishida,&nbsp;M Miyoshi","doi":"10.1007/BF02889550","DOIUrl":"https://doi.org/10.1007/BF02889550","url":null,"abstract":"<p><p>The lymphoma cells from a patient with leukemia lymphoblastic sarcoma (Kiel classification) were observed by scanning and transmission electron microscopy. These cells were also examined by E, EA, EAC rosette-formation tests and by the indirect immunofluorescence technique for surface immunoglobulins. The malignant cells showed failure of rosette-formation or absence of surface immunoglobulins. Scanning electron microscopy revealed that many uniform protrusions were present on the cell surfaces. These surface protrusions were different from those seen on E-or EAC-rosette-forming cells. Ultrastructurally, the malignant cells were characterized by long profiles of rough surfaced endoplasmic reticulum with regular, narrow cisternae which radiated from Golgi area to the periphery of cytoplasm. These appearances differed from those observed in T-or B-lymphoma cells.</p>","PeriodicalId":76800,"journal":{"name":"Virchows Archiv. B, Cell pathology","volume":"26 3","pages":"225-32"},"PeriodicalIF":0.0,"publicationDate":"1978-01-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02889550","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11622909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Aurosomes produced in the synovial membrane by the oral administration of a gold compound SK & F 36914. 通过口服一种金化合物sk&f36914在滑膜中产生的染色体。
Virchows Archiv. B, Cell pathology Pub Date : 1977-12-30 DOI: 10.1007/BF02889539
I Thomas, F N Ghadially
{"title":"Aurosomes produced in the synovial membrane by the oral administration of a gold compound SK & F 36914.","authors":"I Thomas,&nbsp;F N Ghadially","doi":"10.1007/BF02889539","DOIUrl":"https://doi.org/10.1007/BF02889539","url":null,"abstract":"<p><p>Chlorotriethylphosphine gold (SK & F 36914) administered orally to rabbits produced aurosomes in the synovial membrane. These aurosomes were similar to aurosomes produced by parenteral or intra-articular injections of soluble gold salts such as sodium aurothiomalate and aurothioglucose. This study shows, (1) that an orally administered gold compound is capable of producing gold deposits in the synovial membrane, and (2) that such compounds may have a future in the treatment of rheumatoid arthritis.</p>","PeriodicalId":76800,"journal":{"name":"Virchows Archiv. B, Cell pathology","volume":"26 2","pages":"105-9"},"PeriodicalIF":0.0,"publicationDate":"1977-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02889539","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11622658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Histomorphologic and histochemical investigations in mannosidosis. A light and electron microscopic study. 甘露甘露病的组织形态学和组织化学研究。光镜和电子显微镜研究
Virchows Archiv. B, Cell pathology Pub Date : 1977-12-30 DOI: 10.1007/BF02889545
Z Mónus, E Konyár, L Szabó
{"title":"Histomorphologic and histochemical investigations in mannosidosis. A light and electron microscopic study.","authors":"Z Mónus,&nbsp;E Konyár,&nbsp;L Szabó","doi":"10.1007/BF02889545","DOIUrl":"https://doi.org/10.1007/BF02889545","url":null,"abstract":"<p><p>Morphologic and histochemical studies have been performed at light and electron microscopic level on needle-liver biopsy specimens, circulating blood lymphocytes and fibroblast cultures from patients with mannosidosis. The findings demonstrated generalized storage phenomena of varying degrees in the various tissues examined. Histochemical findings were in agreement with the biochemical nature of the stored material. Enzyme histochemical methods indicated storage in the lysosomes, at least in the hepatocytes. The ultrastructural appearance of mannosidosis in itself has but a limited diagnostic significance since the morphology and distribution of vacuoles have characteristics in common with other storage diseases. Repeated liver biopsy disclosed extensive storage in the hepatic tissue. However, the progression of the disease was not accompanied by severe mechanical destruction or microcirculatory disturbances.</p>","PeriodicalId":76800,"journal":{"name":"Virchows Archiv. B, Cell pathology","volume":"26 2","pages":"159-73"},"PeriodicalIF":0.0,"publicationDate":"1977-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02889545","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11621602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 8
Temperature-dependence of the proliferation of mouse bone marrow cells cultured in H2O- and D2O-media. 小鼠骨髓细胞在H2O-和d20培养基中增殖的温度依赖性。
Virchows Archiv. B, Cell pathology Pub Date : 1977-12-30 DOI: 10.1007/BF02889547
H R Maurer, M Wenzel
{"title":"Temperature-dependence of the proliferation of mouse bone marrow cells cultured in H2O- and D2O-media.","authors":"H R Maurer,&nbsp;M Wenzel","doi":"10.1007/BF02889547","DOIUrl":"https://doi.org/10.1007/BF02889547","url":null,"abstract":"<p><p>In an attempto to optimize and standardize the in vitro culture conditions of mouse bone marrow cells for assaying growth regulating factors, we studied the effects of incubation at low temperatures and of a nutrient medium containing deuteriumoxide instead of water. It was found that (1) the proliferative capacity of the cells is significantly increased by pre-incubation for 1-2 h at 0 degrees C rather than at 37 degrees C, measured by both a colony-forming and a 3H-thymidine (3H-tdr) uptake assay. A similar temperature effect on the colony-forming and 3H-tdr uptake ability is apparent after pre-incubation in D2O-medium, yet significantly lower than in H2O-medium. It was concluded that the previously observed protective effects of D2O on ascites tumor cell proliferation and viability and for hemolysis of human erythrocytes is not apparent in proliferating and colony-forming mouse bone marrow cells in vitro.</p>","PeriodicalId":76800,"journal":{"name":"Virchows Archiv. B, Cell pathology","volume":"26 2","pages":"187-93"},"PeriodicalIF":0.0,"publicationDate":"1977-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02889547","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11621604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Multi-tailed spermatozoa in a case with asthenospermia and teratospermia. 弱精子症和畸形精子症的多尾精子。
Virchows Archiv. B, Cell pathology Pub Date : 1977-12-30 DOI: 10.1007/BF02889540
M Nistal, R Paniagua, A Herruzo
{"title":"Multi-tailed spermatozoa in a case with asthenospermia and teratospermia.","authors":"M Nistal,&nbsp;R Paniagua,&nbsp;A Herruzo","doi":"10.1007/BF02889540","DOIUrl":"https://doi.org/10.1007/BF02889540","url":null,"abstract":"<p><p>A case is presented of an infertile male whose spermatozoa showed low mobility, a high percentage of irregular large heads and a variable number of tails (between 0 and 4). In the spermatozoa with several tails each axoneme, surrounded by its own outer fibres and mitochondrial sheath, arose from its own basal plate. Throughout the middle piece of every spermatozoon all the axonemes were arranged in parallel and were enclosed by the same plasma membrane. Usually, at the beginning of the principal piece, the axonemes became separated. At this level each of them constituted a different tail. In most spermatozoa the fine structure of the tail or tails was normal. The alterations of the inner structure of the tail or tails was normal. The alterations of the inner structure of the flagellum observed in some spermatozoa (enlargement of the fibrous sheath, duplication of the outer fibres and of some peripheral doublets) were independent of the number of tails present. In some cases, an intracytoplasmic coiling of the tail or tails could be observed.</p>","PeriodicalId":76800,"journal":{"name":"Virchows Archiv. B, Cell pathology","volume":"26 2","pages":"111-8"},"PeriodicalIF":0.0,"publicationDate":"1977-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02889540","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11622659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 60
alpha-D-mannosidase activity in histiocytosis X. - d -甘露糖苷酶在组织细胞增生症中的活性
Virchows Archiv. B, Cell pathology Pub Date : 1977-12-30 DOI: 10.1007/BF02889543
M Elleder, C Povýsil, J Rozkovcová, J Cihula
{"title":"alpha-D-mannosidase activity in histiocytosis X.","authors":"M Elleder,&nbsp;C Povýsil,&nbsp;J Rozkovcová,&nbsp;J Cihula","doi":"10.1007/BF02889543","DOIUrl":"https://doi.org/10.1007/BF02889543","url":null,"abstract":"<p><p>A histochemical study of enzymatic activities was undertaken in five cases of histiocytosis X (two localized bone forms, two generalized forms, and one involving mainly the skin), each of which revealed characteristic structural features at the optical and ultrastructural levels. A confirmation was made of the original assumption of high acid alpha-D-mannosidase activity, i.e. activity described in human Langerhans intraepidermal cells (Elleder, 1975). In the control group of tumors, with the exception of urticaria pigmentosa, enzyme activity was either at trace level or altogether absent. Acid alpha-D-mannosidase activity therefore appears to be the first biochemical feature common to both histiocytosis X and the Langerhans cells. The significance of the finding for the present theory of the histogenesis of the above tumors is discussed.</p>","PeriodicalId":76800,"journal":{"name":"Virchows Archiv. B, Cell pathology","volume":"26 2","pages":"139-45"},"PeriodicalIF":0.0,"publicationDate":"1977-12-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02889543","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11622661","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 13
首页 上一页
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整，为了账户安全，请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
请完成安全验证×
相关产品
×
本文献相关产品
联系我们：info@booksci.cn Book学术提供免费学术资源搜索服务，方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号：604180095
Book学术官方微信