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The Soviet journal of developmental biology最新文献

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Changes in the pool of deoxyuridine monophosphate in the normal embryogenesis of rats and under the influence of the folic acid antagonist chloridin. 叶酸拮抗剂氯定影响下大鼠正常胚胎发生过程中单磷酸脱氧尿苷池的变化。
The Soviet journal of developmental biology Pub Date : 1975-05-01
B L Vaisman
{"title":"Changes in the pool of deoxyuridine monophosphate in the normal embryogenesis of rats and under the influence of the folic acid antagonist chloridin.","authors":"B L Vaisman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Using the methods of ion exchange and paper chromatography, the content of d-UMP, AMP, GMP, and UMP was measured in 13-15 day rat embryos, and the changes in the pools of these nucleotides under the action of chloridin, one of the inhibitors of dihydrofolate reductase, were also determined. Only the concentration of d-UMP changed appreciably: it increased in the case of normal development from the 13th to the 14th day, apralleling a decrease in the specific activity of TMS, and especially sharply under the action of chloridin, which, inhibiting dihydrofolate reductase, evidently created a deficiency of FA-H4 and thereby blocked the TMS reaction.</p>","PeriodicalId":76730,"journal":{"name":"The Soviet journal of developmental biology","volume":"5 3","pages":"260-3"},"PeriodicalIF":0.0,"publicationDate":"1975-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12303235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Content of DNA and dry weight of the nuclei of neurons of the external geniculate body and retina of the eye in guinea pigs. 豚鼠眼外膝状体和视网膜神经元细胞核DNA含量及干重。
The Soviet journal of developmental biology Pub Date : 1975-05-01
D P Museridze, I K Svanidze, D N Macharashvili
{"title":"Content of DNA and dry weight of the nuclei of neurons of the external geniculate body and retina of the eye in guinea pigs.","authors":"D P Museridze,&nbsp;I K Svanidze,&nbsp;D N Macharashvili","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The amount of DNA and the dry weight of the nuclei of cells of the external geniculate body, as well as the photoreceptor, bipolar, and ganglionic cells of the retina of the eye, were studied at the early stages of postnatal development of guinea pigs by the methods of cytospectrophotometry and interferometry on prints of the tissue. In the photoreceptor and bipolar cells of the retina, a stable, diploid amount of DNA is detected. In the ganglionic cells and nerve cells of the external geniculate body, in addition to the diploid cells a small group of tetraploid cells was detected. The dry weight of the nuclei of the external geniculate body and retina increased appreciably on the third day of postnatal development.</p>","PeriodicalId":76730,"journal":{"name":"The Soviet journal of developmental biology","volume":"5 3","pages":"269-72"},"PeriodicalIF":0.0,"publicationDate":"1975-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12345568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunofluorescent study of thyroglobulin during development of embryonic thyroid gland function. 胚胎甲状腺功能发育过程中甲状腺球蛋白的免疫荧光研究。
The Soviet journal of developmental biology Pub Date : 1975-03-01
N F Grigo'eva
{"title":"Immunofluorescent study of thyroglobulin during development of embryonic thyroid gland function.","authors":"N F Grigo'eva","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The synthesis of the protein component of thyroglobulin was studies by the method of immunofluorescence in the thyroid glands of rat, guinea pig, chicken, and calf embryos. Diffuse specific fluorescence of the cytoplasm was observed in the prefollicular stage of thyroid gland differentiation. It was assumed that the specific fluorescence is due to low molecular weight precursors of thyroglobulin. During the formation of the follicles specific fluorescence is found at the apical poles of the cells and later it is concentrated at the cell-colloid boundary and in the follicular cavity. In calf fetuses in the second half of embryonic development specific fluorescence is observed in addition in the cytoplasm of the follicular cells.</p>","PeriodicalId":76730,"journal":{"name":"The Soviet journal of developmental biology","volume":"5 2","pages":"147-52"},"PeriodicalIF":0.0,"publicationDate":"1975-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12271876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Redistribution of newly synthesized RNA between nucleus and cytoplasm in sea urchin embryos. 海胆胚胎细胞核与细胞质间新合成RNA的再分配。
The Soviet journal of developmental biology Pub Date : 1975-03-01
A V Kotomin, G V Dontsova, A A Neifakh
{"title":"Redistribution of newly synthesized RNA between nucleus and cytoplasm in sea urchin embryos.","authors":"A V Kotomin,&nbsp;G V Dontsova,&nbsp;A A Neifakh","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The kinetics of the release of newly synthesized RNA from the nucleus into the cytoplasm in embryos of the sea urchin Strongylocentrotus nudus was investigated. Preliminary data indicate that some of the newly synthesized RNA may return from the cytoplasm to the nucleus.</p>","PeriodicalId":76730,"journal":{"name":"The Soviet journal of developmental biology","volume":"5 2","pages":"179-81"},"PeriodicalIF":0.0,"publicationDate":"1975-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12303225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Methods of regeneration. 再生方法。
The Soviet journal of developmental biology Pub Date : 1975-03-01
L V Polezhaev
{"title":"Methods of regeneration.","authors":"L V Polezhaev","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This paper is concerned with methods of regeneration: morphallaxis, epimorphosis, and regeneration by induction. The last method was demonstrated by investigations to study the restoration of lost regenerative power of the cranial bones in adult dogs and in some other cases. During regeneration by induction an inducing agent, reactive or competent material, and the right conditions for induction must be present. It is emphasized that the method and mechanism of regeneration are one and the same thing. The methods of regeneration specified above differ not only in their formal and secondary features, but also in the essence of their fundamental processes: true reorganization, growth, and induction. Each method of regeneration can be found not only in the pure form, but also in combinations of varying degree and type. Besides regeneration, hypertrophy is also very important for the restoration of parenchymatous internal organs in mammals, but it is not identical with regenerations.</p>","PeriodicalId":76730,"journal":{"name":"The Soviet journal of developmental biology","volume":"5 2","pages":"134-9"},"PeriodicalIF":0.0,"publicationDate":"1975-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12303395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The genetic and hormonal control of puffing in the salivary gland chromosomes of Drosophila. 果蝇唾液腺染色体中膨化的遗传和激素控制。
The Soviet journal of developmental biology Pub Date : 1975-03-01
M Ashburner
{"title":"The genetic and hormonal control of puffing in the salivary gland chromosomes of Drosophila.","authors":"M Ashburner","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76730,"journal":{"name":"The Soviet journal of developmental biology","volume":"5 2","pages":"97-107"},"PeriodicalIF":0.0,"publicationDate":"1975-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12303226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of retinal factors on the chick-embryo lens in vivo. 视网膜因子对鸡胚晶状体的影响。
The Soviet journal of developmental biology Pub Date : 1975-03-01
K K Guniya, G D Tumanishvili
{"title":"Effect of retinal factors on the chick-embryo lens in vivo.","authors":"K K Guniya,&nbsp;G D Tumanishvili","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of water-soluble retinal factors on lens differentiation in 11-day chick embryos was studies in vivo. Retinal extract accelerated cell transfer from zone to zone, promoted lens-fiber formation, and reduced total protein in the lens. Acrylamide-gel electrophoresis detected four basic protein fractions in the lens. Retinal factors caused a fraction identified as gamma-crystallin to disappear and lowered the peak of delta-crystallin. The data obtained are evidence that retinal factors participate in the regulation of cell differentiation and protein turnover in the lens.</p>","PeriodicalId":76730,"journal":{"name":"The Soviet journal of developmental biology","volume":"5 2","pages":"122-6"},"PeriodicalIF":0.0,"publicationDate":"1975-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12303394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Radioautographic and cytometric analysis of myocyte growth and myocardial regeneration in rats. 大鼠心肌细胞生长和心肌再生的放射自显影和细胞分析。
The Soviet journal of developmental biology Pub Date : 1975-03-01
L V Akhabadze
{"title":"Radioautographic and cytometric analysis of myocyte growth and myocardial regeneration in rats.","authors":"L V Akhabadze","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>During postnatal histogenesis of the rat myocardium DNA synthesis and myocyte proliferation are essentially completed by the 20th-25th day of development, while growth of the muscle cells continues after the 30th day. On the first days following injury of the myocardium of newborn and four-day-old rats the index of labelled nuclei and the mitotic index decrease considerably. Later in myocardial regions adjacent to and remote from the focus of the injury the changes in both indices were identical. No such phenomena were observed in 14-day-old, 30-day-old, and adult rats. After injury in all stages of development a scar formed in the myocardium. It is concluded that regeneration (secondary morphogenesis) does not occur in the myocardium, as assumed earlier, but the process of natural development which had been disturbed by the trauma continues. In the myocardial region remote from the site of the trauma this process, especially in four-day-old rats, is of a compensatory nature. The trauma briefly stimulates myocyte proliferation of the stumps of 14-day-old rats. In the center of the focus of the injury even after the repeated injection of H3-thymidine labelled nuclei were not found in the muscle fibers. This raises doubt as to the possibility of proliferative morphogenesis of muscle fibers located in this region.</p>","PeriodicalId":76730,"journal":{"name":"The Soviet journal of developmental biology","volume":"5 2","pages":"140-6"},"PeriodicalIF":0.0,"publicationDate":"1975-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12303396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Ultrastructure of neurosecretory cells at different stages of differentiation in the preoptic nucleus of immature sterlet. 幼体视前核不同分化阶段神经分泌细胞的超微结构。
The Soviet journal of developmental biology Pub Date : 1975-03-01
I V Yakovleva, N A Efimova, Y I Senchik
{"title":"Ultrastructure of neurosecretory cells at different stages of differentiation in the preoptic nucleus of immature sterlet.","authors":"I V Yakovleva,&nbsp;N A Efimova,&nbsp;Y I Senchik","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ultrastructure of neurosecretory cells of the preoptic nucleus in immature sterlet (Acipenser ruthenus L.) was studies for the first time. The dorsal zone of the preoptic nucleus houses light, dark, and pycnomorphic neurosecretory cells, which contain varying numbers of elementary secretory granules measuring 1995 plus or minus 32 A in diameter. Light cells containing numerous secretory granules with a diameter of 1707 plus or minus 27 A are predominant in the middle zone. Pycnomorphic cells are absent in this zone. The ventral zone contains only poorly differentiated cells with solitary elementary granules measuring 1100-1300 A in diameter. The neurosecretory cells also differ with respect to the number and structural characteristics of their organoids. Thus, neurosecretory cells in the preoptic nucleus are found in different morphofunctional states, a circumstance that reflects the sequence of their development in ontogenesis and different phases of the secretory cycle.</p>","PeriodicalId":76730,"journal":{"name":"The Soviet journal of developmental biology","volume":"5 2","pages":"153-9"},"PeriodicalIF":0.0,"publicationDate":"1975-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12303397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of mitosis in the formation of binuclear cells with a pigmented epithelium of the retina and in the rat liver. 有丝分裂在视网膜和大鼠肝脏中具有色素上皮的双核细胞形成中的作用。
The Soviet journal of developmental biology Pub Date : 1975-03-01
T L Marshak
{"title":"The role of mitosis in the formation of binuclear cells with a pigmented epithelium of the retina and in the rat liver.","authors":"T L Marshak","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The formation of binuclear tetraploid cells in the pigmented epithelium of the retina and the rat liver was investigated by the method of autoradiography using H3-thymidine. It was shown that binuclear cells are formed in these tissues as a result of incomplete mitosis. Only mononuclear diploid cells participate in the formation of these cells in the livers of 24-day-old animals, while in the pigmented epithelium of the retina of four-day-old animals, in addition binuclear tetraploid cells also participate. The duration of the phases of the mitotic cycle of cells of the pigmented epithelium of the rat retina and liver was determined.</p>","PeriodicalId":76730,"journal":{"name":"The Soviet journal of developmental biology","volume":"5 2","pages":"166-71"},"PeriodicalIF":0.0,"publicationDate":"1975-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12303399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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