R Moyou-Somo, L G Lehman, S Awahmukalah, P Ayuk Enyong
{"title":"Deltamethrin impregnated bednets for the control of urban malaria in Kumba Town, South-West Province of Cameroon.","authors":"R Moyou-Somo, L G Lehman, S Awahmukalah, P Ayuk Enyong","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study was conducted from January to December 1992 in Kumba, a town situated in the rain forest region of the South-West Province of Cameroon, and consisted of a longitudinal survey including parasitological and clinical studies. Forty households were chosen for the study and randomly divided into two groups, each with approximately 240 inhabitants aged < or = 15 years. One group received deltamethrin impregnated bednets and the other group had no nets (control). For the months of April, June and August (rainy season), deltamethrin impregnated bednets did not reduce malaria prevalence significantly, but the overall malaria prevalence for all months of the study was significantly reduced (chi 2 MH = 9.17, P = 0.002). Enlarged spleen rates (chi 2 MH = 6.73, P = 0.009) and spleen sizes (P = 0.0002) were also significantly reduced by the nets. However, the reduction in the geometric mean parasite density (GMPD) was not significant. Even though some of these reductions were statistically significant, they were relatively low in a global context compared with previous work done mainly in rural areas. In an urban environment, parents and children usually stay up late, and probably receive many mosquito bites before going to sleep.</p>","PeriodicalId":76688,"journal":{"name":"The Journal of tropical medicine and hygiene","volume":"98 5","pages":"319-24"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18570432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cyclospora cayetanensis associated with watery diarrhoea in Peruvian patients.","authors":"R Zerpa, N Uchima, L Huicho","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Acid-fast, coccidian-like bodies (Cyclospora cayetanensis) were identified over the last 18 months in the stools of seven Peruvian patients suffering from diarrhoea. The follow-up of two patients revealed a watery, self-limited diarrhoea, which lasted for up to four weeks. The organism was simultaneously identified in the diarrhoeal stools of three members of the same family who drank unchlorinated canal water and in the stools of a duck bred by this family. The organism was not found in the faecal samples of 50 healthy subjects and 10 ducks bred by families without known diarrhoea cases. These findings, albeit preliminary, may be suggesting that besides consumption of untreated water, additional modes of transmission such as contact with domestic animals may be important in this disease. Further studies are needed to assess whether this disease behaves as a zoonotic condition and to ascertain the relative importance of symptom-free subjects in person-to-person transmission of the organism.</p>","PeriodicalId":76688,"journal":{"name":"The Journal of tropical medicine and hygiene","volume":"98 5","pages":"325-9"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18570433","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Characterization of group A streptococci isolated in Kuala Lumpur, Malaysia.","authors":"F Jamal, S Pit, D R Johnson, E L Kaplan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>T-agglutination patterns of 190 strains of group A streptococci isolated between January 1989 and December 1993 from body fluids (10), throat culture (56), pus (51) and skin lesions (73) were determined. Mucoid colonial morphology was exhibited by 6.3% (12/190) of the strains on initial isolation. Type T-5,11,27,44 comprised 23.7%, followed by T-1,3,13,B3264 (11.1%), T-4,6 (8.4%) and T-8,25, Imp 19 (7.9%). About 42% (80/190) strains could not be characterized by T agglutination pattern. T-typing of 71 selected strains at WHO Collaborating Center, Minneapolis yielded similar results. Nineteen selected strains were further characterized by M-typing; only three strains were M-typeable. These strains were isolated from throat (M1), sputum (M5) and pus (M12). About 68% (48/71) isolates produced serum opacity factor. These data support the existence of as yet uncharacterized group A streptococcal serotypes in this region.</p>","PeriodicalId":76688,"journal":{"name":"The Journal of tropical medicine and hygiene","volume":"98 5","pages":"343-6"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18568270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Urban to rural routes of HIV infection spread in Ethiopia.","authors":"I Shabbir, C P Larson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A descriptive survey to identify routes of spread of HIV infection from urban to rural populations was carried out in a rural south-central Ethiopian district. High risk practices for HIV infection and transmission were first documented among rural residing former soldiers, merchants and students. Extramarital intercourse during the previous 3 months was reported by 45-50% of these subgroups. In 25-37%, intercourse with an urban commercial sex worker (CSW) was reported and condom use varied from 10 to 30% among subgroups. The perceived risk for AIDS was low and changes in risk behaviours were minimal. Next, 502 rural males farmers were surveyed. An extramarital sexual contact in the past 3 months was reported by 13.5%, with 7% reporting their most recent contact with an urban CSW. Only 6% of farmers reported using condoms. Awareness of AIDS was reported by 59% and, of these, only 28% perceived they were vulnerable. In this study increased knowledge was associated with more frequent high risk sexual practices. It is concluded that the spread of AIDS into rural communities is occurring as a result of the high frequency of high risk sexual behaviours in specific rural residing subgroups which frequently travel into urban communities in combination with a low background prevalence of high risk practices among the general male farmer population.</p>","PeriodicalId":76688,"journal":{"name":"The Journal of tropical medicine and hygiene","volume":"98 5","pages":"338-42"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18570436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Growth and development.","authors":"D Bradley","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76688,"journal":{"name":"The Journal of tropical medicine and hygiene","volume":"98 5","pages":"1"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18569660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S I Adagu, J N Okoyeh, L Lege-Oguntoye, W N Ogala, G O Ogunrinde, J T Faji, A H Sani
{"title":"Efficacy of a 3-day oral regimen of quinine in an area of northern Nigeria with low-grade resistance of Plasmodium falciparum to chloroquine and sulphadoxine-pyrimethamine.","authors":"S I Adagu, J N Okoyeh, L Lege-Oguntoye, W N Ogala, G O Ogunrinde, J T Faji, A H Sani","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The efficacy in vivo of a 3-day oral regimen of quinine (30 mg/kg/day) was assessed in 34 children with falciparum malaria in an area of northern Nigeria with previously documented low-grade parasite resistance to chloroquine and sulphadoxine-pyrimethamine (SDX/PYR). By day 4, all 34 children were free of parasites. Mean parasite clearance time and fever clearance time were 2.7 and 1.7 days, respectively. However, on day 14, 5 (14.7%) children were again parasitaemic and 4 of them were clinically ill. They were again treated successfully with a standard course of oral chloroquine. No adverse drug effects were recorded. Of the 34 children, 9 parasite isolates were successfully cultured in vitro. EC50 and EC99 were 14.0 and 126.0 pmol per well respectively, indicating decreased parasite sensitivity but no resistance in vitro. In conclusion, the 3-day course of quinine was found to be an effective alternative to standard chloroquine treatment in the study area.</p>","PeriodicalId":76688,"journal":{"name":"The Journal of tropical medicine and hygiene","volume":"98 5","pages":"296-8"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18569662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Z Vukovic, A Bobic-Radovanovic, Z Latkovic, Z Radovanovic
{"title":"An epidemiological investigation of the first outbreak of rhinosporidiosis in Europe.","authors":"Z Vukovic, A Bobic-Radovanovic, Z Latkovic, Z Radovanovic","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Until January 1992 rhinosporidiosis was unknown in the Balkans. The outbreak which took place at that time in northern Serbia (Yugoslavia) affected 17 people over a period of less than two years. The number of patients in this epidemic exceeded the total number of autochthonous cases of rhinosporidiosis ever recorded in Europe. The male-to-female ratio was 10:7 and, except for a middle-aged man, all patients were in the age range 6-16 years. Preponderance of ocular (12) over nasal (5) localization of the disease in this epidemic indicates that the real number of cases may be much higher. The only experience all patients had in common was that they spent their holiday preceding the onset of symptoms bathing in the same accumulation of stagnant water (the Silver Lake). A case-control study showed that the odds of being exposed to that particular environment by chance were extremely remote.</p>","PeriodicalId":76688,"journal":{"name":"The Journal of tropical medicine and hygiene","volume":"98 5","pages":"333-7"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18570435","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K Nakashima, S Kashiwagi, A Noguchi, M Hirata, J Hayashi, T Kawasaki, K Uezono, K Itoh, G P Acharya, M Ogata
{"title":"Human T-lymphotropic virus type-I, and hepatitis A, B and C viruses in Nepal: a serological survey.","authors":"K Nakashima, S Kashiwagi, A Noguchi, M Hirata, J Hayashi, T Kawasaki, K Uezono, K Itoh, G P Acharya, M Ogata","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 1987, 676 blood samples were collected from inhabitants of the Bhadrakali and Kotyang villages in Nepal. The samples were tested for the prevalence of antibody to hepatitis A virus (anti-HAV), hepatitis B surface antigen (HBsAg), antibody to hepatitis B core antigen (anti-HBc), second-generation antibody to hepatitis C virus (anti-HCV) and antibody to human T-lymphotropic virus type-I (anti-HTLV-I). Anti-HAV was present in 99.3% of the people surveyed. The prevalence of anti-HAV reached 100% in the < 25 age group and was as high or only slightly lower in all other age groups. The prevalence of HBsAg was 0.3% and of anti-HBc 7.7%. Anti-HCV was found in 0.1% of the residents. No significant difference by gender or village was noted in the prevalence of anti-HAV, HBsAg, anti-HBc, or anti-HCV. No anti-HTLV-I-positive persons were identified. These data suggest that the prevalence of hepatitis B and C virus infections in Nepal is low in contrast to hepatitis A virus infection, and that human T-lymphotropic type-I infection may be absent in this population.</p>","PeriodicalId":76688,"journal":{"name":"The Journal of tropical medicine and hygiene","volume":"98 5","pages":"347-50"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18568271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Takayasu's arteritis in Kuwait.","authors":"K el-Reshaid, J Varro, Q al-Duwairi, J T Anim","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The present study describes the epidemiological profile and clinical features of Takayasu's arteritis (TA) in Kuwait, as well as its association with other autoimmune diseases and primary hypercoagulable states. Thirteen patients were included from its start on 1 January 1989 till 30 June 1994. Diagnosis of TA was established by angiographic studies. Twelve patients were Arabs and 7 were Kuwaiti nationals. Five patients were males and renal disease secondary to isolated involvement of the abdominal aorta (TA, type II) was the main presentation in 4 patients. Coagulation tests were performed in 7 patients and included antiphospholipid antibody (aPL) assay as well as protein S, protein C and antithrombin III activity. Only one manifested recurrent thrombosis and laboratory tests confirmed the presence of a hypercoagulable state secondary to aPL and protein S deficiency. Serological tests of systemic lupus erythematosis (SLE) were positive in this patient. These data indicate that TA is not a rare disease in the Arabic population. In our study, female predominance was not a common feature of TA and renal disease secondary to TA type II disease was commonly encountered. The association of TA with SLE and primary hypercoagulable states was not a consistent finding in our patients with TA, and hence, the proposed role for thrombotic vasculopathy in the pathogenesis and progression of this disease was unfounded.</p>","PeriodicalId":76688,"journal":{"name":"The Journal of tropical medicine and hygiene","volume":"98 5","pages":"299-305"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18569663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Das, P Nalini, S Ananthakrishnan, P H Ananthanarayanan, J Balachander, K R Sethuraman, S Srinivasan
{"title":"Scorpion envenomation in children in southern India.","authors":"S Das, P Nalini, S Ananthakrishnan, P H Ananthanarayanan, J Balachander, K R Sethuraman, S Srinivasan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The clinical presentation of 32 children with scorpion envenomation was analysed. The most common presentation was cold, clammy extremities with normal blood pressure. Myocarditis was present in 16 children (50%) and encephalopathy in four (12.5%). Two children died. ECG was a sensitive indicator of myocarditis which was subclinical in four children. Left ventricular dysfunction was a transient phenomenon. Myocarditis and encephalopathy were the two lethal complications observed. Serum free fatty acid levels were elevated two to three-fold in all symptomatic patients. Blood glucose levels were only mildly elevated and serum amylase levels and electrolytes were normal in all the children. No specific antivenom was given. In the absence of specific antivenom, early and active supportive treatment reduces the morbidity and mortality due to scorpion envenomation.</p>","PeriodicalId":76688,"journal":{"name":"The Journal of tropical medicine and hygiene","volume":"98 5","pages":"306-8"},"PeriodicalIF":0.0,"publicationDate":"1995-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18570429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}