The Journal of otolaryngology最新文献

{"title":"Does subjective tinnitus cause sexual disturbance?","authors":"Nuray Bayar Muluk,&nbsp;Mehmed Murad Başar,&nbsp;Omer Oğuztürk,&nbsp;Oğuzhan Dikici","doi":"10.2310/7070.2007.0002","DOIUrl":"https://doi.org/10.2310/7070.2007.0002","url":null,"abstract":"<p><strong>Objective: </strong>Tinnitus can cause psychological problems, which can affect sexual performance. The aim of this study was to investigate sexual disturbance related to the psychological problems of patients with subjective tinnitus.</p><p><strong>Materials and method: </strong>The subjective tinnitus group with normal hearing levels consisted of 20 patients (10 male, 10 female) who were nonpsychiatric. The control group consisted of 20 healthy patients (10 male, 10 female) with normal hearing levels who did not have tinnitus and were nonpsychiatric. All subjects were married and had an active sexual life. Using a questionnaire, the subjective tinnitus loudness level score (STLL-Sc) was found. Using Zung Anxiety and Depression Scale, self-rating depression scale (SDS) was found in the study and control groups. Sexual function was assessed in all male subjects with the International Index of Erectile Functions (IIEF) and in all female subjects with the Female Sexual Function Index (FSFI).</p><p><strong>Results: </strong>In females, the satisfaction subscore was slightly lower than normal limits in both the study and control groups. In males, the IIEF showed an insignificant, negative correlation with the STLL-Sc and the SDS and a positive correlation with tinnitus duration. In females, the FSFI showed an insignificant negative correlation with the STLL-Sc and a positive correlation with tinnitus duration and the SDS.</p><p><strong>Conclusion: </strong>Sexual disturbance is seen in very quiet- and intermediate-level tinnitus sufferers in the early period of the disease. Over time, they become used to living with their tinnitus, and no loss in sexual performance is seen. In the future, we plan to investigate the sexual disturbance of patients with severe STLL-Scs.</p>","PeriodicalId":76656,"journal":{"name":"The Journal of otolaryngology","volume":"36 2","pages":"77-82"},"PeriodicalIF":0.0,"publicationDate":"2007-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2310/7070.2007.0002","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26687264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The submental island flap: a regional and free flap with a myriad of reconstructive applications.","authors":"Kevin M Higgins,&nbsp;Richard Backstein","doi":"10.2310/7070.2007.0011","DOIUrl":"https://doi.org/10.2310/7070.2007.0011","url":null,"abstract":"","PeriodicalId":76656,"journal":{"name":"The Journal of otolaryngology","volume":"36 2","pages":"88-92"},"PeriodicalIF":0.0,"publicationDate":"2007-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2310/7070.2007.0011","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26687266","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of ossicular prosthesis mass and section of the stapes tendon on middle ear transmission.","authors":"Manohar Bance,&nbsp;David P Morris,&nbsp;Rene Van Wijhe","doi":"10.2310/7070.2007.0008","DOIUrl":"https://doi.org/10.2310/7070.2007.0008","url":null,"abstract":"<p><strong>Background: </strong>The effects of changing prosthesis mass on middle ear transmission have not been previously systematically studied. Neither has the effect of stapes tendon sectioning. These are important parameters that can be surgically varied.</p><p><strong>Hypothesis: </strong>Because the middle ear is compliance dominated at low frequencies, prosthesis mass will affect transmission of higher frequencies in the middle ear.</p><p><strong>Methods: </strong>Eight fresh cadaveric temporal bones, with the incus removed, were loaded with a replacement prosthesis from the tympanic membrane to the stapes head. Laser Doppler vibrometry was used to measure stapes footplate vibrations. Vibrations were measured in response to chirps from 250 to 8 kHz at 90 dB SPL in the ear canal. The unloaded prosthesis mass was approximately 16 mg. Loadings with masses of approximately 2, 12, and 30 mg were placed on the stem. Recordings were repeated after cutting the stapes tendon.</p><p><strong>Results: </strong>Mass loading affected the higher frequencies only, with significant effects only above 4 kHz. There was little low-frequency effect. Stapes tendon section showed an improvement in the lower frequencies but did not reach statistical significance.</p><p><strong>Conclusions: </strong>Mass of prostheses affects mainly higher frequencies. There is no drop in lower frequencies from using lower masses, so lighter-mass prostheses may be preferred. Stapes tendon section does not have a detrimental effect on middle ear transmission after ossiculoplasty.</p>","PeriodicalId":76656,"journal":{"name":"The Journal of otolaryngology","volume":"36 2","pages":"113-9"},"PeriodicalIF":0.0,"publicationDate":"2007-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2310/7070.2007.0008","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26687723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"P27 and MIB-1 expression is related to malignancy recurrence in laryngeal carcinoma treated with partial laryngectomy: preliminary results.","authors":"Nicola Calgaro,&nbsp;Gino Marioni,&nbsp;Stella Blandamura,&nbsp;Luciano Giacomelli,&nbsp;Roberto Stramare,&nbsp;Andy Bertolin,&nbsp;Alberto Staffieri,&nbsp;Cosimo de Filippis","doi":"10.2310/7070.2007.0004","DOIUrl":"https://doi.org/10.2310/7070.2007.0004","url":null,"abstract":"<p><strong>Objective: </strong>Considerable evidence has confirmed that p27 protein plays a negative role in cell-cycle progression from the G1 to the S phase and is considered a tumour suppressor. p27 down-regulation was demonstrated in several malignancies. Only a few studies investigated p27's potential prognostic role in laryngeal squamous cell carcinoma (SCC). The aim of the present study was to determine the prognostic relevance of p27 expression in a cohort of laryngeal SCCs that were very homogeneous from a treatment viewpoint to avoid possible influences of treatment modalities on results; all patients underwent only partial laryngectomy on the primary lesion. We simultaneously investigated monoclonal antibody against a proliferating cell associated epitope MIB-1 expression.</p><p><strong>Design and methods: </strong>Twenty-two cases of laryngeal SCC that had undergone exclusive supracricoid or supraglottic laryngectomies with or without neck dissection at the Department of Otolaryngology of Padova University were evaluated. Primary laryngeal SCC p27 reactivity and MIB-1 reactivity were immunohistochemically tested and evaluated by a workstation image analysis system.</p><p><strong>Main outcome measures: </strong>A lesion was considered p27 positive when more than 18.56% of the tumour cells showed diffuse strong staining. Samples with > 20.24% of stained cells were considered MIB-1 positive.</p><p><strong>Results: </strong>The mean p27 expression was 17% and 22% in patients with and without disease recurrence, respectively. Low p27 expression was statistically associated with disease recurrence (p = .045); on the other hand, high MIB-1 values were associated with SCC recurrence after treatment (p = .045).</p><p><strong>Conclusions: </strong>The intervals of confidence analysis showed a stronger relationship of MIB-1 versus p27 in predicting disease recurrence in our cohort of patients treated only with partial laryngectomies.</p>","PeriodicalId":76656,"journal":{"name":"The Journal of otolaryngology","volume":"36 2","pages":"98-105"},"PeriodicalIF":0.0,"publicationDate":"2007-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2310/7070.2007.0004","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26687720","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary mucosal melanoma of the nasal cavity and paranasal sinuses: 12 years of experience.","authors":"Shiang-Fu Huang,&nbsp;Chun-Ta Liao,&nbsp;Chun-Ran Kan,&nbsp;I-How Chen","doi":"10.2310/7070.2007.0010","DOIUrl":"https://doi.org/10.2310/7070.2007.0010","url":null,"abstract":"<p><strong>Introduction: </strong>Melanomas that arise in the nasal cavity or paranasal sinuses are rare and have a poor prognosis. In this study, we reviewed 15 patients in a tertiary referral centre and analyzed their treatment results and patterns of treatment failure.</p><p><strong>Materials and methods: </strong>Fifteen patients diagnosed from January 1994 to February 2005 at the Chang Gung Memorial Hospital were retrospectively reviewed.</p><p><strong>Results: </strong>Eight men (53.3%) and seven (46.7%) women ranged in age from 51 to 85 years (mean 69.0 years) at the time of diagnosis. All patients presented with symptoms related to the nose. The majority of patients presented with epistaxis (93.3%). Ten patients received surgery and postoperative radiotherapy, three patients received surgery and postoperative chemo- and radiotherapy, and one patient received radiotherapy alone. The overall actuarial survival revealed that 49.5% were alive at 2 years and 33.0% were alive at 5 years. The average time from surgery to local recurrence was 5 months, the average time from surgery to the occurrence of regional recurrence was 7.45 months, and the time from surgery to the diagnosis of distant metastasis was 10.3 months. The sites of distant metastasis according to frequency are the lung, liver, bone, and brain. The average survival after the diagnosis of distant metastasis was 8 months.</p><p><strong>Conclusion: </strong>The prognosis of mucosal melanoma of the nasal cavity is poor in our experience. Most of the local recurrence, regional recurrence, and distant metastasis occurs in the first year after surgery. For those patients in the first year after surgery, frequent and regular follow-up is mandatory.</p>","PeriodicalId":76656,"journal":{"name":"The Journal of otolaryngology","volume":"36 2","pages":"124-9"},"PeriodicalIF":0.0,"publicationDate":"2007-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2310/7070.2007.0010","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26687725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radiation-induced soft tissue sarcomas of the head and neck.","authors":"Gerhard F Huber,&nbsp;T Wayne Matthews,&nbsp;Joseph C Dort","doi":"10.2310/7070.2007.0001","DOIUrl":"https://doi.org/10.2310/7070.2007.0001","url":null,"abstract":"<p><strong>Purpose: </strong>To describe the occurrence of radiation-induced soft tissue sarcomas in a retrospectively analyzed cohort of patients. To analyze the histologic subtypes and survival in this rare disease.</p><p><strong>Patients and methods: </strong>While performing a retrospective analysis of soft tissue sarcomas in patients treated between 1974 and 1999 at the two major cancer centres in Alberta (Canada), eight patients presenting with nine sarcomas occurring in a previously radiated site were identified. Eight fulfilled the criteria for radiation-induced sarcoma.</p><p><strong>Results: </strong>Radiation-induced sarcomas occurred between 10 months and more than 50 years after irradiation (median 7.35 years). Patients' ages ranged from 36 to 88 years (median 77.3 years) at the time of their sarcoma diagnosis. Histologically, four malignant fibrous histiocytomas, two dermatofibrosarcoma protuberans, two carcinosarcomas, and one fibrosarcoma were diagnosed. All patients received surgery as the primary treatment. Complete resection could not be achieved in three cases. Two of them died of disease. The 5-year disease-specific survival rate was 50%, whereas the 5-year overall survival rate was 25%.</p><p><strong>Conclusions: </strong>Radiotherapy can induce malignancies after a latency period of a few months to several years. Radiation-induced sarcomas are associated with poor overall prognosis. The treatment in most cases is late and ineffective. The population at risk for the development of radiation-induced sarcoma is increasing, so vigilance is required in the follow-up of those patients.</p>","PeriodicalId":76656,"journal":{"name":"The Journal of otolaryngology","volume":"36 2","pages":"93-7"},"PeriodicalIF":0.0,"publicationDate":"2007-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2310/7070.2007.0001","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26687719","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thyroid scintigraphy in the assessment of the solitary thyroid nodule: differences in practice patterns between family physicians and specialists.","authors":"Tariq A Kassum,&nbsp;David P Goldstein,&nbsp;Mark A Rafferty,&nbsp;Lorne E Rotstein,&nbsp;Jonathan C Irish","doi":"10.2310/7070.2006.0060","DOIUrl":"https://doi.org/10.2310/7070.2006.0060","url":null,"abstract":"<p><strong>Objective: </strong>It has been shown that there is considerable variation in the diagnosis and management of the thyroid nodule. The purpose of this study was to investigate the differences in the practice of family physicians and specialists in ordering thyroid scans in the initial workup of patients with thyroid nodules.</p><p><strong>Design: </strong>Retrospective electronic and paper-based chart review.</p><p><strong>Setting: </strong>University Health Network, Toronto.</p><p><strong>Participants: </strong>All patients who underwent thyroidectomy over a 2-year period.</p><p><strong>Interventions: </strong>An audit of their preoperative diagnostic tests was performed, and the specialties of the ordering physicians were identified.</p><p><strong>Results: </strong>One hundred ninety-four patients were assessed. Sixty-three patients (32.5%) were investigated exclusively by their family physician, 63 (32.5%) were investigated exclusively by a specialist, and 68 (35%) were investigated by both. Family physicians ordered thyroid scans in 51% of patients, whereas specialists ordered scans in 29% of patients (p<.001). The medical specialists ordered 36 scans (33.6%) in 107 patients, whereas the surgical specialists ordered 2 (8.3%) scans in 24 patients (p<.001).</p><p><strong>Conclusion: </strong>Despite the limited role for thyroid scans in the initial workup of a solitary thyroid nodule, they are still frequently ordered, particularly by family physicians. We recommend publication of Canadian evidence-based guidelines for the management of thyroid nodules, similar to existing American guidelines, which could help reduce the amount of unnecessary testing.</p>","PeriodicalId":76656,"journal":{"name":"The Journal of otolaryngology","volume":"36 1","pages":"49-53"},"PeriodicalIF":0.0,"publicationDate":"2007-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2310/7070.2006.0060","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26617200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Iatrogenic bilateral inverted papilloma: case report and literature review.","authors":"Krista Rodriguez-Bruno,&nbsp;M Jafer Ali,&nbsp;Steven J Wang","doi":"10.2310/7070.2006.0068","DOIUrl":"https://doi.org/10.2310/7070.2006.0068","url":null,"abstract":"","PeriodicalId":76656,"journal":{"name":"The Journal of otolaryngology","volume":"36 1","pages":"72-5"},"PeriodicalIF":0.0,"publicationDate":"2007-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2310/7070.2006.0068","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26617205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effectiveness of hyperbaric oxygen on sudden sensorineural hearing loss: prospective clinical research.","authors":"Kadir Dundar,&nbsp;Tuna Gumus,&nbsp;Hakan Ay,&nbsp;Sertac Yetiser,&nbsp;Eylem Ertugrul","doi":"10.2310/7070.2006.0061","DOIUrl":"https://doi.org/10.2310/7070.2006.0061","url":null,"abstract":"<p><p>The role of hyperbaric oxygen (HBO) treatment in sudden sensorineural hearing loss (SSNHL) is still controversial. In this study, 80 patients were treated for SSNHL. Fifty-five patients who received HBO and medical treatment and 25 patients who received medical treatment only were studied. There was a statistically significant difference between the HBO and medical treatment group and the medical treatment group for hearing gain and the degree of hearing loss after treatment (p<.05). In the HBO and medical treatment group, patients with tinnitus showed the highest hearing improvement. The patients who had tinnitus had a statistically significant difference for hearing gain in the HBO and medical treatment group (p<.05) but not in the medical treatment group (p>.05). In the HBO and medical treatment group, average hearing gain on each audiometric frequency was better than in the medical treatment group (p<.05).</p>","PeriodicalId":76656,"journal":{"name":"The Journal of otolaryngology","volume":"36 1","pages":"32-7"},"PeriodicalIF":0.0,"publicationDate":"2007-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2310/7070.2006.0061","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26218259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Change in health status after rhinoplasty.","authors":"Mark R Draper,&nbsp;Mahmoud A Salam,&nbsp;Sanjiv Kumar","doi":"10.2310/7070.2006.0050","DOIUrl":"https://doi.org/10.2310/7070.2006.0050","url":null,"abstract":"<p><strong>Objective: </strong>To assess the change in health status of patients undergoing rhinoplasty.</p><p><strong>Design: </strong>Retrospective mail-based questionnaire study using a validated post-intervention questionnaire specifically designed for otolaryngology surgery.</p><p><strong>Setting: </strong>District general hospital otolaryngology department.</p><p><strong>Patients: </strong>All patients (78 in total) undergoing rhinoplasty surgery between October 1998 and November 2003 were included in the study.</p><p><strong>Main outcome measure: </strong>Glasgow Benefit Inventory, a validated post-intervention questionnaire specifically designed for otolaryngologic surgery.</p><p><strong>Results: </strong>The mean total Glasgow Benefit Inventory score was +20.0 (95% confidence interval [CI] 14.2-25.9), and the mean general, social, and physical subscale scores were +25.0 (95% CI 17.3-32.7), +10.2 (95% CI 4.4-16.0), and +9.9 (95% CI 2.7-17.0), respectively.</p><p><strong>Conclusions: </strong>Our results show that the health status of patients undergoing rhinoplasty improved overall and according to each of the subscales used.</p>","PeriodicalId":76656,"journal":{"name":"The Journal of otolaryngology","volume":"36 1","pages":"13-6"},"PeriodicalIF":0.0,"publicationDate":"2007-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.2310/7070.2006.0050","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"26218256","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}