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Regulation of store-operated calcium currents in mast cells. 肥大细胞储存操作钙电流的调节。
Society of General Physiologists series Pub Date : 1996-01-01
A B Parekh, R Penner
{"title":"Regulation of store-operated calcium currents in mast cells.","authors":"A B Parekh, R Penner","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"51 ","pages":"231-9"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19778779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Regulation of vacuolar acidification. 液泡酸化的调节。
Society of General Physiologists series Pub Date : 1996-01-01
M Forgac
{"title":"Regulation of vacuolar acidification.","authors":"M Forgac","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"51 ","pages":"121-32"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19779497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single channel properties and calcium conductance of the cloned expressed ryanodine receptor/calcium-release channel. 克隆表达的ryanodine受体/钙释放通道的单通道特性和钙电导。
Society of General Physiologists series Pub Date : 1996-01-01
K Ondrias, A M Brillantes, A Scott, B E Ehrlich, A R Marks
{"title":"Single channel properties and calcium conductance of the cloned expressed ryanodine receptor/calcium-release channel.","authors":"K Ondrias,&nbsp;A M Brillantes,&nbsp;A Scott,&nbsp;B E Ehrlich,&nbsp;A R Marks","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The calcium-release channel/ryanodine receptor of the sarcoplasmic reticulum is a 2.3 million-D structure required for intracellular calcium release during excitation-contraction coupling in skeletal muscle. This structure is the largest ion channel characterized to date and is composed of four 565,000-D ryanodine receptors plus four molecules of FKBP12. In the present study we describe the single channel properties of the cloned expressed ryanodine receptor, with and without FKBP12, reconstituted into planar lipid bilayers with Ca as the charge carrier. The conductance for Ca (luminal, 53 mM/cytoplasmic, 10 microM) was 103 pS for the cloned expressed RyR and for the native channel from rabbit skeletal muscle. Conductance through the channel was Ca dependent: A decrease in the Ca gradient to luminal 10.6/cytoplasmic 10 microM reduced conductance to 68 pS for both the cloned and native RyR. The recombinant ryanodine receptor consistently behaved like the native skeletal muscle channel in terms of activation by caffeine, calcium, and ATP; inhibition by ruthenium red; and modulation by ryanodine. In the absence of FKBP12, the cloned expressed RyR exhibited multiple subconductance states and addition of FKBP12 reduced the frequency of subconductance states. These results show that with Ca as the charge carrier, the single channel properties of the cloned expressed RyR plus FKBP12 are essentially the same as those of the native channel.</p>","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"51 ","pages":"29-45"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19779491","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Nuclear ion channels and regulation of the nuclear pore. 核离子通道与核孔的调控。
Society of General Physiologists series Pub Date : 1996-01-01
L Stehno-Bittel, C Perez-Terzic, A Luckhoff, D E Clapham
{"title":"Nuclear ion channels and regulation of the nuclear pore.","authors":"L Stehno-Bittel,&nbsp;C Perez-Terzic,&nbsp;A Luckhoff,&nbsp;D E Clapham","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Multiple K+, Cl-, and nonselective cationic nuclear channels have been identified in a variety of cell types from coconut endosperm to cardiac myocytes. To date, only one ligand-gated nuclear channel has been characterized-the InsP3R-but it is likely that others are also present. The InsP3R channel has been implicated in two important nuclear events: (1) nuclear vesicle fusion (Sullivan et al., 1993) and (2) regulation of molecular transport through the nuclear pore (Stehno-Bittel et al., 1993) and (2) 1995b). Regulation of passive diffusion across the nuclear envelope by the nuclear Ca2+ store may play an important role in nuclear events ranging from apoptosis to cell division.</p>","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"51 ","pages":"195-207"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19779503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transporters of nucleotides and nucleotide derivatives in the endoplasmic reticulum and Golgi apparatus. 内质网和高尔基体中核苷酸和核苷酸衍生物的转运体。
Society of General Physiologists series Pub Date : 1996-01-01
C B Hirschberg
{"title":"Transporters of nucleotides and nucleotide derivatives in the endoplasmic reticulum and Golgi apparatus.","authors":"C B Hirschberg","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"51 ","pages":"105-20"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19779496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
MscL: a mechanosensitive channel in Escherichia coli. MscL:大肠杆菌中的一个机械敏感通道。
Society of General Physiologists series Pub Date : 1996-01-01
S I Sukharev, P Blount, B Martinac, H R Guy, C Kung
{"title":"MscL: a mechanosensitive channel in Escherichia coli.","authors":"S I Sukharev,&nbsp;P Blount,&nbsp;B Martinac,&nbsp;H R Guy,&nbsp;C Kung","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"51 ","pages":"133-41"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19779498","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The ADP/ATP transport system: a paradigm of metabolite transport in mitochondria. ADP/ATP转运系统:线粒体代谢物转运的范例。
Society of General Physiologists series Pub Date : 1996-01-01
G Brandolin, A Le Saux, P Roux, V Trezeguet, C Fiore, C Schwimmer, A C Dianoux, G J Lauquin, P V Vignais
{"title":"The ADP/ATP transport system: a paradigm of metabolite transport in mitochondria.","authors":"G Brandolin,&nbsp;A Le Saux,&nbsp;P Roux,&nbsp;V Trezeguet,&nbsp;C Fiore,&nbsp;C Schwimmer,&nbsp;A C Dianoux,&nbsp;G J Lauquin,&nbsp;P V Vignais","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"51 ","pages":"173-85"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19779501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Positive and negative regulation of depletion-activated calcium channels by calcium. 钙对消耗激活钙通道的正负调节。
Society of General Physiologists series Pub Date : 1996-01-01
R S Lewis, R E Dolmetsch, A Zweifach
{"title":"Positive and negative regulation of depletion-activated calcium channels by calcium.","authors":"R S Lewis,&nbsp;R E Dolmetsch,&nbsp;A Zweifach","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"51 ","pages":"241-54"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19778780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functional properties of inositol 1,4,5-trisphosphate receptor and Ca2+ signaling. 肌醇1,4,5-三磷酸受体和Ca2+信号的功能特性。
Society of General Physiologists series Pub Date : 1996-01-01
M Iino
{"title":"Functional properties of inositol 1,4,5-trisphosphate receptor and Ca2+ signaling.","authors":"M Iino","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"51 ","pages":"67-73"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19779493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Functional significance of membrane architecture in skeletal and cardiac muscle. 骨骼肌和心肌膜结构的功能意义。
Society of General Physiologists series Pub Date : 1996-01-01
C Franzini-Armstrong
{"title":"Functional significance of membrane architecture in skeletal and cardiac muscle.","authors":"C Franzini-Armstrong","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76550,"journal":{"name":"Society of General Physiologists series","volume":"51 ","pages":"3-18"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19779489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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