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Series haematologica (1968)最新文献

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Megakaryocytes in agar cultures of mouse bone marrow. 小鼠骨髓琼脂培养中的巨核细胞。
Series haematologica (1968) Pub Date : 1975-01-01
A Nakeff, K A Dicke, M J Noord van
{"title":"Megakaryocytes in agar cultures of mouse bone marrow.","authors":"A Nakeff,&nbsp;K A Dicke,&nbsp;M J Noord van","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cytologic and immunofluorescent data demonstrate that cells morphologically resembling megakaryocytes appear in thin layer agar cultures of cellular fractions of mouse bone marrow and increase in number from zero to a maximum of approxiamately 60 per culture on day 6. It would appear that these \"candidate\" megakaryocytes are derived from a morphologically unidentified precursor(s) since they are not present in the original cell suspension cultured but begin to appear 24 hours later. Similarities between the ultrastructure of \"candidate\" megakaryocytes and that of femoral marrow megakaryocytes support morphological similarities at the light microscopic level. Pretreatment of mice with either vinblastine and nitrogen mustard or antiplatelet serum has no effect on the number of \"candidate\" megakaryocytes appearing in cultures of their marrow. Preliminary data suggest that the rate of appearance of these cells in culture is responsive to serum from thrombocytopenic donors.</p>","PeriodicalId":76538,"journal":{"name":"Series haematologica (1968)","volume":"8 1","pages":"4-21"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12274567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Platelet kinetics--1975. 血小板动力学——1975。
Series haematologica (1968) Pub Date : 1975-01-01
C A Ries
{"title":"Platelet kinetics--1975.","authors":"C A Ries","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Studies of platelet kinetics have provided useful information regarding the role of platelets in the pathogenesis of thrombosis and related disorders. Additionally, platelet survival studies have been useful in evaluating the efficacy of drugs that may be useful as platelet inhibitors. Many questions remain, however, and answers are needed before much of the kinetic data can be confidently applied to clinical problems in thrombosis.</p>","PeriodicalId":76538,"journal":{"name":"Series haematologica (1968)","volume":"8 3","pages":"98-104"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12410324","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Classification and possible mechanisms of action of some drugs that inhibit platelet aggregation. 一些抑制血小板聚集药物的分类和可能的作用机制。
Series haematologica (1968) Pub Date : 1975-01-01
H Holmsen
{"title":"Classification and possible mechanisms of action of some drugs that inhibit platelet aggregation.","authors":"H Holmsen","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76538,"journal":{"name":"Series haematologica (1968)","volume":"8 3","pages":"50-80"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11402503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A clinical trial of early splenectomy, hydroxyurea, and cyclic arabinosyl cytosine, vincristine, and prednisone in chronic myeloid leukemia. Italian Cooperative Study Group on Chronic Myeloid Leukemia. 早期脾切除术、羟基脲、环阿拉伯糖胞嘧啶、长春新碱和强的松治疗慢性髓性白血病的临床试验。意大利慢性髓性白血病合作研究组。
Series haematologica (1968) Pub Date : 1975-01-01
{"title":"A clinical trial of early splenectomy, hydroxyurea, and cyclic arabinosyl cytosine, vincristine, and prednisone in chronic myeloid leukemia. Italian Cooperative Study Group on Chronic Myeloid Leukemia.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76538,"journal":{"name":"Series haematologica (1968)","volume":"8 4","pages":"121-42"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11987747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aspirin revisited. 阿司匹林再现。
Series haematologica (1968) Pub Date : 1975-01-01 DOI: 10.12968/npre.2012.10.4.161
R. Rodvein, A. R. Cooke
{"title":"Aspirin revisited.","authors":"R. Rodvein, A. R. Cooke","doi":"10.12968/npre.2012.10.4.161","DOIUrl":"https://doi.org/10.12968/npre.2012.10.4.161","url":null,"abstract":"ASA is a safe drug to relieve pain, lessen fever, diminish the inflammatory reaction and treat arthritis. This drug can be given to people in a very safe soluble and buffered form which minimizes its major potential side effect: G.I. bleeding. The G.I. bleeding seen with ASA is due to its local effect on the gastric mucosa. The evidence that exists shows that ASA's effect upon the platelet does not contribute to the gastric bleeding. It is unclear to what extent those diseases mediated by thrombosis can be prevented by ASA and other platelet-suppressive drugs. Thrombosis is not equivalent to hemostasis, but is a distortion of the hemostatic process. Clinical trials are now underway but they will probably be inconclusive. Presently, the literature is contradictory and, therefore, the decision to use ASA as an anti-thrombotic durg remains with the individual physician.","PeriodicalId":76538,"journal":{"name":"Series haematologica (1968)","volume":"44 1","pages":"141-50"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82620351","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Platelets: the last hundred years. 血小板:过去的一百年。
Series haematologica (1968) Pub Date : 1975-01-01
C H Mielke
{"title":"Platelets: the last hundred years.","authors":"C H Mielke","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76538,"journal":{"name":"Series haematologica (1968)","volume":"8 3","pages":"5-22"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11980795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparative studies of bone marrow and extramedullary haemopoietic tissue in chronic myeloid leukemia. 慢性髓性白血病骨髓与髓外造血组织的比较研究。
Series haematologica (1968) Pub Date : 1975-01-01
L Brandt
{"title":"Comparative studies of bone marrow and extramedullary haemopoietic tissue in chronic myeloid leukemia.","authors":"L Brandt","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76538,"journal":{"name":"Series haematologica (1968)","volume":"8 4","pages":"75-80"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12251432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Agar culture studies in CML and blastic transformation. CML的琼脂培养及囊胚转化研究。
Series haematologica (1968) Pub Date : 1975-01-01
M A Moore
{"title":"Agar culture studies in CML and blastic transformation.","authors":"M A Moore","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76538,"journal":{"name":"Series haematologica (1968)","volume":"8 4","pages":"11-27"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12251584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasma lysozyme--a measure of neutrophil turnover. An analytical review. 血浆溶菌酶——中性粒细胞周转的量度。分析性评论。
Series haematologica (1968) Pub Date : 1974-01-01
N E Hansen
{"title":"Plasma lysozyme--a measure of neutrophil turnover. An analytical review.","authors":"N E Hansen","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76538,"journal":{"name":"Series haematologica (1968)","volume":"7 1","pages":"1-87"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15705180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Immunological aspects of the etiology of human leukemia. 人类白血病病因学的免疫学方面。
Series haematologica (1968) Pub Date : 1974-01-01
R Penny
{"title":"Immunological aspects of the etiology of human leukemia.","authors":"R Penny","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76538,"journal":{"name":"Series haematologica (1968)","volume":"7 2","pages":"274-99"},"PeriodicalIF":0.0,"publicationDate":"1974-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15252567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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