Research publications - Association for Research in Nervous and Mental Disease最新文献_第2页

Questions and prospects related to HIV-1 and the brain. 与HIV-1和大脑有关的问题和前景。

Research publications - Association for Research in Nervous and Mental Disease Pub Date : 1994-01-01

R T Johnson

引用次数: 0

HIV dementia. Incidence and risk factors. 艾滋病痴呆。发病率和危险因素。

Research publications - Association for Research in Nervous and Mental Disease Pub Date : 1994-01-01

J C McArthur, O A Selnes, J D Glass, D R Hoover, H Bacellar

引用次数: 0

Cellular neuropathology in HIV encephalitis. HIV脑炎的细胞神经病理学。

Research publications - Association for Research in Nervous and Mental Disease Pub Date : 1994-01-01

E Masliah, C L Achim, N Ge, R De Teresa, C A Wiley

引用次数: 0

Cytokine expression and pathogenesis in AIDS brain. 艾滋病脑细胞因子表达及发病机制。

Research publications - Association for Research in Nervous and Mental Disease Pub Date : 1994-01-01

L Vitkovic, A da Cunha, W R Tyor

引用次数: 0

Evaluation and treatment of psychiatric disorders associated with HIV infection. 与HIV感染相关的精神障碍的评估和治疗。

Research publications - Association for Research in Nervous and Mental Disease Pub Date : 1994-01-01

G Treisman, M Fishman, C Lyketsos, P R McHugh

引用次数: 0

Understanding the AIDS dementia complex (ADC). The challenge of HIV and its effects on the central nervous system. 了解艾滋病痴呆复合体(ADC)。艾滋病毒的挑战及其对中枢神经系统的影响。

Research publications - Association for Research in Nervous and Mental Disease Pub Date : 1994-01-01

R W Price

引用次数: 0

Neuropathology and pathogenesis of SIV infection of the central nervous system. SIV感染中枢神经系统的神经病理学和发病机制。

Research publications - Association for Research in Nervous and Mental Disease Pub Date : 1994-01-01

L R Sharer

引用次数: 0

HIV-related depression. 与艾滋病毒相关的抑郁。

Research publications - Association for Research in Nervous and Mental Disease Pub Date : 1994-01-01

S W Perry

{"title":"HIV-related depression.","authors":"S W Perry","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>While there is still much to be learned about depression in the context of HIV illness, studies over the past decade are generally reassuring. True, low-grade depressive symptoms are frequent among both HIV-positive and at-risk HIV-negative adults, but depressive disorders are the exception and not the rule, occurring in about 1 of 10 individuals. Similar to non-HIV populations, these depressive disorders are more likely to occur among those HIV-infected adults with severe personality problems, with a history of previous depressions, and with limited current social support. Although rates of depression may slightly increase with development of more severe physical symptoms, even then the clinician should not consider the presence of a depressive disorder as understandable, justified, and therefore \"normal.\" Rather, depressive symptoms accompanied by suicidal ideation are signals for further evaluation and treatment. When antidepressant treatment is indicated, the weight of current evidence suggests that standard therapies can be safely and effectively prescribed for HIV-infected adults. For outpatients without severe physical illness, antidepressant medications are generally well tolerated in recommended dosages and do not increase immunosuppression. For those with more severe physical impairment, the adage for geriatric populations is applicable: \"Start low and go slow.\" If lethargy and cognitive slowing is a major component of the depression, especially among those in later stages of disease, then psychostimulants may be helpful. When concerns about drug abuse preclude such a prescription, an activating antidepressant may be just as helpful to improve both mood and energy. For severe or refractory depressions, such as delusional affective disorders. ECT has been safely given to HIV-infected patients. And finally, accumulated clinical experience and a couple of systematic studies suggest that psychotherapy, alone or in combination with antidepressant drug therapy, can be remarkably beneficial. In sum, data support the fact that we have much to offer our depressed HIV-infected patients. Our task is to make sure that we identify their depressions when present and counter their feelings of hopelessness by ensuring that effective antidepressant treatments are provided.</p>","PeriodicalId":76423,"journal":{"name":"Research publications - Association for Research in Nervous and Mental Disease","volume":"72 ","pages":"223-38"},"PeriodicalIF":0.0,"publicationDate":"1994-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19107800","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Genetic and biologic basis of HIV-1 neurotropism. HIV-1嗜神经性的遗传和生物学基础。

Research publications - Association for Research in Nervous and Mental Disease Pub Date : 1994-01-01

W A O'Brien

引用次数: 0

Molecular and cellular organization of the central nervous system: implications for new therapeutics. 中枢神经系统的分子和细胞组织:对新疗法的启示。

Research publications - Association for Research in Nervous and Mental Disease Pub Date : 1993-01-01

S G Waxman

引用次数: 0