Reproduccion最新文献_第2页

Evaluation of maternal and fetal leukocyte migration test after normal deliveries; the role of maternal and fetal serum in the leukocyte migration assay. 正常分娩后母胎白细胞迁移试验的评价母胎血清在白细胞迁移试验中的作用。

Reproduccion Pub Date : 1982-07-01

L Komlos, I Halbrecht, J Goldman

引用次数: 0

Reconstructive microsurgery of the female reproductive tract utilizing the carbon dioxide laser. 利用二氧化碳激光重建女性生殖道的显微外科。

Reproduccion Pub Date : 1982-07-01

J H Bellina

引用次数: 0

[Barrier methods of contraception]. [屏障避孕法]。

Reproduccion Pub Date : 1982-07-01

A Goldsmith, D A Edelman

引用次数: 0

Extended view of the menopause. 更年期的扩展视图。

Reproduccion Pub Date : 1982-04-01

R B Greenblatt

引用次数: 0

Biologic effect of a hybrid preparation of human chorionic gonadotropin in human subjects. 人绒毛膜促性腺激素混合制剂在人体内的生物学效应。

Reproduccion Pub Date : 1982-04-01

E Rosemberg

引用次数: 0

Ovulation-inhibiting properties of Org OD 14. Org OD 14的排卵抑制特性。

Reproduccion Pub Date : 1982-04-01

P Franchimont, F Franchi, M Luisi, P M Kicovic

{"title":"Ovulation-inhibiting properties of Org OD 14.","authors":"P Franchimont, F Franchi, M Luisi, P M Kicovic","doi":"","DOIUrl":"","url":null,"abstract":"Org OD 14 has recently been shown to be an interesting new steroid for the treatment of menopausal women. In view of the importance of treatment of perimenopausal women, in whom ovulation might occur, the aim of the present study was to assess whether or not Org OD 14, administered orally in a daily dose of 2.5 mg for 21 days, inhibits ovulation. Sixteen healthy female volunteers, aged 20-34 years and with established ovulatory cycles, were studied during a control cycle and a treatment cycle. Daily measurements of the plasma levels of FSH, LH, E2, P and PRL were made. Endometrial specimens were obtained from nine of the volunteers between 23rd and 25th day of both cycles. The criteria for an ovulatory cycle were: (1) mid-cycle FSH, LH and E2 peaks; (2) criteria (1) followed by a rise in the P levels of greater than 10 ng/ml; (3) a luteal phase of at least 12 days; (4) biphasic behaviour of E2; and, (5) secretory endometrium on days 23-25 of the cycle. All control cycles were ovulatory. During the treatment the mid-cycle FSH, LH and E2 peaks disappeared, and P levels remained very low. PRL levels showed an occasional moderate rise in some of the volunteers. Endometrial specimens showed a secretory pattern during the control cycle, and different degrees of proliferation during the treatment cycle in all nine volunteers. It was concluded that Org OD 14 inhibited ovulation in all 16 volunteers.","PeriodicalId":76418,"journal":{"name":"Reproduccion","volume":"6 2","pages":"61-7"},"PeriodicalIF":0.0,"publicationDate":"1982-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17866772","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Placebo-controlled cross-over study of effects of Org OD 14 in menopausal women. 绝经期妇女Org OD 14作用的安慰剂对照交叉研究。

Reproduccion Pub Date : 1982-04-01

P M Kicovic, J Cortés-Prieto, M Luisi, S Milojevic, F Franchi

{"title":"Placebo-controlled cross-over study of effects of Org OD 14 in menopausal women.","authors":"P M Kicovic, J Cortés-Prieto, M Luisi, S Milojevic, F Franchi","doi":"","DOIUrl":"","url":null,"abstract":"A double-blind cross-over study with Org OD 14 and placebo was performed in 82 menopausal patients presenting with hot flushes and associated symptoms. Patients were randomly allocated to Org OD 14 or placebo as first treatment, and switched to placebo or Org OD 14 as second treatment. Each treatment period lasted for 16 weeks; no wash-out period was introduced. Tablets containing 2.5 mg of Org OD 14 or matched placebo tablets were supplied. Data on the following variables were obtained and analysed by the non-parametric randomization test for paired observations: hot flushes, sweating, dizziness, palpitations, fatiguability, headache, sleeplessness, irritability, breathlessness, backache and loss of libido and, in 16 patients, on circulating levels of FSH, LH, PRL, T3, T4, cortisol (F), SHBG, TBG and CBG. Twenty patients (13 placebo, 7 Org OD 14) withdrew, because their symptoms did not improve and one patient withdrew for reasons unrelated to treatment, so that 61 patients completed the study. The data demonstrated a good clinical effect and statistically significant differences in favour of Org OD 14 for hot flushes and a number of associated symptoms. Many patients reported on a general feeling of well being and a mood-elevating effect following Org OD 14. Org OD 14 significantly suppressed FSH and LH levels, while those of PRL remained unchanged. Although there was slight suppression of TBG and T4 which attained statistical significance, there was no influence on the most important parameter, T3. SHBG levels were slightly suppressed, whereas F and CBG levels were unaffected.","PeriodicalId":76418,"journal":{"name":"Reproduccion","volume":"6 2","pages":"81-91"},"PeriodicalIF":0.0,"publicationDate":"1982-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17809126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A comparative study of clomiphene and epimestrol on plasma progesterone, CBG, TBG and SHBG, and salivary progesterone levels. 克罗米芬与epimestrel对血浆孕酮、CBG、TBG、SHBG及唾液孕酮水平的影响比较研究。

Reproduccion Pub Date : 1982-04-01

P M Kicovic, M Luisi, J Cortés-Prieto, F Franchi

{"title":"A comparative study of clomiphene and epimestrol on plasma progesterone, CBG, TBG and SHBG, and salivary progesterone levels.","authors":"P M Kicovic, M Luisi, J Cortés-Prieto, F Franchi","doi":"","DOIUrl":"","url":null,"abstract":"The plasma levels of CBG, TBG, SHBG and progesterone, and salivary progesterone levels were measured in eight young ovulatory volunteers. After the control cycle four subjects received 50 mg/day of Clomiphene from days 5 to 9 of the first treatment cycle, and 10 mg/day of Epimestrol from days 5 to 15 of the second treatment cycle. The other four subjects received the treatments in reverse order. Between the two treatments there was one cycle without medication as a \"wash-out\" period. Plasma and saliva samples were obtained on days +6, +8 and +10 (day of LH peak was denoted by 0), always between 08.00 and 09.00 h. Statistical evaluation was done by means of an analysis of variance (ANOVA), and correlation coefficients were also calculated. Evaluation of data on effects of Clomiphene and Epimestrol on the plasma levels of CBG and salivary progesterone showed that Clomiphene induced a highly significant rise (p less than 0.001) in the CBG levels and decrease (p less than 0.001) in salivary progesterone levels, while no changes were seen following administration of Epimestrol. Both Clomiphene and Epimestrol treatments led towards higher plasma progesterone levels, those following Clomiphene administration being higher. Neither treatment induced significant changes in TBG or SHBG levels. It is concluded that Clomiphene induces significant elevations of CBG and decrease in salivary progesterone, which is thought to reflect the free progesterone fraction and may have significance in relation to a discrepancy between the ovulation and pregnancy rates following Clomiphene therapy.","PeriodicalId":76418,"journal":{"name":"Reproduccion","volume":"6 2","pages":"133-40"},"PeriodicalIF":0.0,"publicationDate":"1982-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17940317","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The pathophysiology of postmenopausal hot flushes. 绝经后潮热的病理生理学。

Reproduccion Pub Date : 1982-04-01

P Lomax

引用次数: 0

Lack of suppression of increased circulating prolactin by 2-hydroxyestrone. 缺乏2-羟孕酮对循环泌乳素增加的抑制作用。

Reproduccion Pub Date : 1982-04-01

P M Kicovic, F Franchi, M Luisi

引用次数: 0