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Placebo-controlled study of effects of epimestrol on the pituitary-testicular axis in normal men. 乙酰甲孕酮对正常男性垂体-睾丸轴影响的安慰剂对照研究。
Reproduccion Pub Date : 1980-01-01
M Luisi, P M Kicóvíc, F Franchi
{"title":"Placebo-controlled study of effects of epimestrol on the pituitary-testicular axis in normal men.","authors":"M Luisi,&nbsp;P M Kicóvíc,&nbsp;F Franchi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Twenty healthy male volunteers were randomly allocated to the treatment with either 15 mg/day of epimestrol or placebo for 10 days. The plasma levels of luteinizing hormone (LH), follicle-stimulating hormone (FSH), testosterone (T), oestradiol (E2) and prolactin (PRL) were measured before, during and 4 days after the medication by radioimmunoassays. Data were statistically evaluated by means of an analysis of covariance. Circulating LH and FSH, and also T and E2 significantly increased in the epimestrol treated subjects. In the placebo treated subjects no significant changes in the plasma hormone levels were observed. There were no significant changes in the plasma levels of PRL in either group.</p>","PeriodicalId":76418,"journal":{"name":"Reproduccion","volume":"4 1","pages":"77-83"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17823710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Plasma profile of pituitary gonadotropins and ovarian steroids in patients with unexplained infertility. 不明原因不孕症患者垂体促性腺激素和卵巢类固醇的血浆特征。
Reproduccion Pub Date : 1980-01-01
E Rosemberg
{"title":"Plasma profile of pituitary gonadotropins and ovarian steroids in patients with unexplained infertility.","authors":"E Rosemberg","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76418,"journal":{"name":"Reproduccion","volume":"4 1","pages":"1-19"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17823708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Abortion or contraception (author's transl)]. 堕胎或避孕(作者译)。
Reproduccion Pub Date : 1980-01-01
A Goldsmith, D A Edelman
{"title":"[Abortion or contraception (author's transl)].","authors":"A Goldsmith,&nbsp;D A Edelman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The period immediately following an abortion, spontaneous or induced, has been considered favourable to the initiation of high efficicy contraception: sterilization, oral contraceptives, or intrauterine devices. The rate of post-abortal complications associated with these contraceptive methods was evaluated using data drawn from published and unpublished studies. The following conclusions were reached: sterilization is advisable only for women who do not desire additional children, and is obviously not recommended for young nulliparous women. The effective use of oral contraceptives requires a high motivational level and is therefore advisable only in cases where such motivation exists. The insertion of an intrauterine device seems to be the most adequate contraceptive method for women with low motivational level.</p>","PeriodicalId":76418,"journal":{"name":"Reproduccion","volume":"4 1","pages":"55-68"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18401427","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The role of age, smoking habits, and oral contraceptives in the frequency of myocardial infarction in young women (author's transl)]. [年龄、吸烟习惯和口服避孕药在年轻女性心肌梗死发生率中的作用[作者译]。
Reproduccion Pub Date : 1980-01-01
J W Goldzieher
{"title":"[The role of age, smoking habits, and oral contraceptives in the frequency of myocardial infarction in young women (author's transl)].","authors":"J W Goldzieher","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Owing to the discussion aroused by different papers which have appeared in the last few years on the possible side-effects of oral contraceptives, an examination is made in this paper of the methods used in some of these studies, trying to elucidate to what extent we can trust the conclusions obtained, in order to decide whether oral contraceptives, by themselves, are a real and considerable risk to women's health, and analysing the role of oral contraceptives associated with other risk factors which can influence the frequency of myocardial infarction in young women. It is concluded that the use of oral contraceptives does not represent a statistically significant risk and, therefore, a causal inference cannot be attributed to them; but there exist other risk factors which prove to be of statistically demonstrable danger for myocardial infarction, such as smoking and obesity. Also, it seems evident that the combined effect of smoking and oral contraceptive use is synergistic. However, even though these two factors associated can increase the risk of myocardial infarction, we must not dismiss the possibility of this increment being influenced by other, equally logical circumstances.</p>","PeriodicalId":76418,"journal":{"name":"Reproduccion","volume":"4 1","pages":"21-7"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18401628","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Campos da Paz award: fetal cardiovascular effects produced by asphyxia (author's transl)]. [Campos da Paz奖:窒息对胎儿心血管的影响[作者简介]。
Reproduccion Pub Date : 1980-01-01
J H Sabatino
{"title":"[Campos da Paz award: fetal cardiovascular effects produced by asphyxia (author's transl)].","authors":"J H Sabatino","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76418,"journal":{"name":"Reproduccion","volume":"4 1","pages":"29-48"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18401629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Urinary oestriol excretion and the lecithin/sphingomyelin ratio in amniotic fluid in Bogota (2600 m) I. Normal pregnancy (author's transl)]. [波哥大(2600米)地区尿雌三醇排泄和羊水卵磷脂/鞘磷脂比值1 .正常妊娠(作者译)]。
Reproduccion Pub Date : 1980-01-01
L A Sobrevilla, M Cristina Peña, R Jaramillo
{"title":"[Urinary oestriol excretion and the lecithin/sphingomyelin ratio in amniotic fluid in Bogota (2600 m) I. Normal pregnancy (author's transl)].","authors":"L A Sobrevilla,&nbsp;M Cristina Peña,&nbsp;R Jaramillo","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We have studied 22 pregnancies in order to establish normal values for the urinary oestriol excretion in Bogotá, a city 2600 metres above sea level. The study subjects were normal pregnant women attending the prenatal clinic of the Hospital San José de Bogotá, and belong to a racially mixed community of medium to low socio-economic level. In the study, new born weight was found low (mean +/- SEM 2.97 +/-0.06 kg) while placental weight was high (0.6 +/- 0.02 kg) with a high placenta/newborn ratio. Maternal hemoglobin was elevated (12.8 +/- 0.2g/100 ml) reflecting the effect of altitude. In 66 determinations, oestriol excretion was more than 4mg/24 hours from week 31 to 36 and of more than 5 mg/24 hours from week 35 to 40. The decreased excretion of oestriol most likely reflects impaired intrauterine fetal growth, and is probably related to nutrional, racial and socio-economic factors as well as to the altitude. In five normal term pregnancies studied, the lecithin/sphingomyelin ratio was of 2 or more and amniotic fluid creatinine was also elevated, indicating maturity of the pulmonary and renal enzyme systems of the fetus.</p>","PeriodicalId":76418,"journal":{"name":"Reproduccion","volume":"4 1","pages":"69-75"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18401428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Doses-related effects of lynestrenol on ovulation (author's transl)]. [林奈雌醇对排卵的剂量相关影响(作者译)]。
Reproduccion Pub Date : 1976-07-01
M A Pizarro, K Thomas, J Ferin
{"title":"[Doses-related effects of lynestrenol on ovulation (author's transl)].","authors":"M A Pizarro,&nbsp;K Thomas,&nbsp;J Ferin","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76418,"journal":{"name":"Reproduccion","volume":"3 3-4","pages":"193-205"},"PeriodicalIF":0.0,"publicationDate":"1976-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11989013","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Serum luteinizing hormone follicle-stimulating hormone and prolactin in neonatal-androgenized rats. 新生雄激素化大鼠血清促黄体激素、促卵泡激素和催乳素。
Reproduccion Pub Date : 1976-07-01
J A Moguilevsky, P Scacchi, D Dosoretz, L Rubinstein
{"title":"Serum luteinizing hormone follicle-stimulating hormone and prolactin in neonatal-androgenized rats.","authors":"J A Moguilevsky,&nbsp;P Scacchi,&nbsp;D Dosoretz,&nbsp;L Rubinstein","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Serum levels of LH, FSH, Prolactin and Testosterone of 90 days old male rats androgenized soon after birth were determined by specific radioimmunoassay and were compared to untreated rats. LH and FSH levels were also determined in 90 days old female rats neo-natally treated with testosterone and compared with normal diestrus rats. Androgenization of male rats significantly increased serum FSH and Prolactin levels without producing changes in plasma LH and testosterone concentrations. Similar increase in the FSH levels were found in androgenized female rats although plasma FSH concentrations were lower than in the male groups. These results obtained in male rats give an additional evidence that androgens acting in the first days of life are responsible of the higher levels of FSH and Prolactin that characterize the male or tonic pattern of gonadotrophin secretion.</p>","PeriodicalId":76418,"journal":{"name":"Reproduccion","volume":"3 3-4","pages":"273-7"},"PeriodicalIF":0.0,"publicationDate":"1976-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12213434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The effect of androgens upon the differentiation of Cowper and Bartholin glands in rat fetuses (author's transl)]. [雄激素对大鼠胎鼠考伯腺和巴托林腺分化的影响[作者译]。
Reproduccion Pub Date : 1976-07-01
J Vilanova Trias, J San Molina
{"title":"[The effect of androgens upon the differentiation of Cowper and Bartholin glands in rat fetuses (author's transl)].","authors":"J Vilanova Trias,&nbsp;J San Molina","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the present paper, a study is made of the normal structure shown in Bartholin and Cowper glands of 100 female fetuses and 100 male fetuses of Wistar rats at the end of gestation, with the structure of bulbouretral glands that formed in 70 female fetuses of the same species and period of gestation masculinized by androgens. In relation to the Bartholin glands, whose bilateral sketch is constant in the fetuses, we can affirm that it shows significant differences of structure with regards to the sketch of the Cowper gland. On the opposite, the histologycal details of the latter, are entirely identical to those shown by the bulbouretral glands of the masculinized female fetuses, a fact which permits us to affirm that these are authentic Cowper glands, not only because of their position, but also because of their structure. This morphological data corresponds to a masculinization phenomenon and demonstrates that the Bartholin and Cowper glands are very sensitive to the effect of androgens during gestation.</p>","PeriodicalId":76418,"journal":{"name":"Reproduccion","volume":"3 3-4","pages":"265-72"},"PeriodicalIF":0.0,"publicationDate":"1976-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12213436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[The urinary excretion of pregnanediol during pregnancy determined by gas-liquid chromatography. I. Its evolution throughout the normal and pathological pregnancy (author's transl)]. 用气液色谱法测定妊娠期尿中妊娠二醇的排泄。1 .其在正常妊娠和病理妊娠期间的演变(作者译)。
Reproduccion Pub Date : 1976-07-01
P Acien, M Dolz, E Luque, J A Gómez-Capilla, M E Campos-Bañales
{"title":"[The urinary excretion of pregnanediol during pregnancy determined by gas-liquid chromatography. I. Its evolution throughout the normal and pathological pregnancy (author's transl)].","authors":"P Acien,&nbsp;M Dolz,&nbsp;E Luque,&nbsp;J A Gómez-Capilla,&nbsp;M E Campos-Bañales","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Employing the technique described by Van Kampen and Anker, modified by Macarulla et al., 180 pregnant women have been studied (66 normals and 114 with different pathology: infertility, toxemia, diabetes, Rh isoinmunization, gemelar pregnancy and abortions), taking 319 determinations of pregnanediol in 24 hours urine samples. The analysis of the results show in normal pregnancy a progressive increase of the urinary pregnanediol from the beginning of gestation, this increase being more intense from the 20th week, reaching the maximum value in the 37th week and from this point descending slowly. In patients with toxemia, the values of pregnanediol (in the majority of the cases) are decreased, while in pregnant women with antecedents of infertility are increased from the 36th week of pregnancy, although they had protective treatment from first months of pregnancy. No manifest deviations of urinary pregnanediol from the normal values exist in diabetic pregnant women, Rb isoinmunization or gemelar pregnancies. In aborted pregnancies the pregnanediol values are markedly decreased without a tendency to increase, contrary to the threats of abortion in full-term pregnancies.</p>","PeriodicalId":76418,"journal":{"name":"Reproduccion","volume":"3 3-4","pages":"207-17"},"PeriodicalIF":0.0,"publicationDate":"1976-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12213602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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