{"title":"[Psychotropic effects of antiepileptic drugs].","authors":"L W Diehl","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Today the rank taken by antiepileptic drugs in the complex conditional fabric of mental disorders in epilepsies is well known. There are direct as well as indirect psychotropic effects caused by medication quite independent of other disorders which epilepsy based on or correlated with. It is of particular practical significance to control the concentration of drugs and their metabolic interactions by means of plasma levels which has nothing to do with a 'therapy of plasma levels'. The significance of plasma concentration, however, is becoming more and more evident. There exist today several antiepileptic drugs, meanwhile well researched and properly applied, which achieve, in terms of frequency and intensity, that progressively less mental disorders develop, establish or become chronic.</p>","PeriodicalId":76382,"journal":{"name":"Psychiatria clinica","volume":"16 5-6","pages":"305-15"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17702725","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Dexamethasone suppression test combined with total sleep deprivation in depressed patients.","authors":"S Kasper, H W Moises, H Beckmann","doi":"10.1159/000283947","DOIUrl":"https://doi.org/10.1159/000283947","url":null,"abstract":"<p><p>The effect of one night's total sleep deprivation (SD) on the dexamethasone suppression test (DST) was studied in groups of endogenously and nonendogenously depressed patients who were diagnosed according to different research classification systems. The DST was normal (less than 5 micrograms/dl) before and after SD in the group of nonendogenously depressed patients. Deterioration, no change or only slight clinical response in single items occurred. In the group of endogenous depressives 8 out of 11 were baseline nonsuppressors (greater than 5 micrograms/dl). After SD a large variability of cortisol nonsuppression was found in this group. Clinical response occurred in the majority of these patients but was more favorable in those who had a trend for normalization of DST. Clinical diagnosis as well as DST seem to have a therapy-predictive value for one night's total SD in patients with affective disorders.</p>","PeriodicalId":76382,"journal":{"name":"Psychiatria clinica","volume":"16 1","pages":"17-25"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000283947","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17896154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Levels of interaction between schizophrenia and manic-depressive disease.","authors":"O H Arnold","doi":"10.1159/000283970","DOIUrl":"https://doi.org/10.1159/000283970","url":null,"abstract":"<p><p>Interaction between schizophrenia and manic-depressive disease (MDI) has to be examined with respect to type, intensity and time points within the courses. Interactions are possible at the level of genetics, constitution, biological (e.g. biorhythmical) mechanisms, neurophysiological actions, biochemical complexes and psychopathological interferences including defense mechanisms of personality. The common denominator seems to be the energetic situation into the satellite-glia-neuron cooperation. Activity of G6PD and AK 2-1 could be a hint of a factor of bipolarity, existing independently from schizophrenia and MDI. Interactions of different psychoses should be designated as interference psychoses. Within this field, the term schizoaffective characterizes the interference between schizophrenia and MDI, mixed psychoses mean stages of rapidly alternating or stable combinations of symptoms within the MDI. 'Legierungspsychosen' should be reserved for interferences at the genetic level.</p>","PeriodicalId":76382,"journal":{"name":"Psychiatria clinica","volume":"16 2-4","pages":"217-23"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000283970","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17635260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Mood-congruent/incongruent dichotomy. The need for an advanced mood concept.","authors":"W F Pritz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Initially, some arguments are brought forward why, at the present state of differential diagnosis, it is useful to apply the term schizo-affective disorder. The basic considerations concern the consequences of the semantic confusion between mood and affect and how this affects differential diagnosis of functional psychoses. The view is maintained that from an action theoretic model mood states have to be conceptualized as differing forms of pragmatics of reality creation and self-interpretation (in other words, as multilogic of self-observation, self-protection, self-repair, and of the relativistic and reflective structure of inter- and intrapersonal communication). The concept of mood congruency/incongruency is meaningful only as a metaconcept in regard to emotional connotation, perceptive operations, cognitive processes, nonverbal expressions, autonomic parameters, and so on.</p>","PeriodicalId":76382,"journal":{"name":"Psychiatria clinica","volume":"16 2-4","pages":"297-304"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17677613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Schizo-affective disorder, manic type. A clinical, laboratory, and genetic study.","authors":"M A Taylor, R Abrams","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We studied a sample of 111 Feighner manics divided into 42 'pure' manics without any schizophrenic features, 41 manics with one such feature, and 28 with two or more such features. The three groups did not significantly differ on any major demographic, clinical, historical, treatment response, laboratory, or familial variable tested. We also applied the DSM-III schizophrenia and schizophreniform criteria to these 111 Feighner manics. Only 1 manic had an index episode longer than 6 months (a necessary criterion for schizophrenia), whereas 13 (12%) satisfied the schizophreniform criteria. We compared these 13 Feighner manics satisfying DSM-III schizophreniform criteria with the remaining 97 Feighner manics and could find no major demographic, clinical, or laboratory differences between the two groups. Although not statistically significant, the morbidity risk for affective disorder in the first-degree relatives of the 97 Feighner manics was three times the risk in the relatives of the Feighner manics who also satisfied the DSM-III schizophreniform criteria. The morbidity risk for alcoholism in these relatives was one-half that of first-degree relatives of the 'schizophreniform' manics. The two groups did not differ in total risk for alcoholism and affective disorder.</p>","PeriodicalId":76382,"journal":{"name":"Psychiatria clinica","volume":"16 2-4","pages":"234-44"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17678748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Schizo-affective psychoses from a phenomenological-anthropological point of view.","authors":"A Kraus","doi":"10.1159/000283975","DOIUrl":"https://doi.org/10.1159/000283975","url":null,"abstract":"<p><p>The presence of schizo-affective psychosis is postulated psychopathologically, if schizophrenic as well as manic or depressive cyclothymic symptoms, respectively, are to be found in the same clinical picture. This circumstance rises the question with what legitimation do we designate a symptom as schizophrenic, etc.? Generally, we call a symptom, e.g., schizophrenic, if: (1) like with K. Schneider's first-rank symptoms the presence of a schizophrenic called entity of syndrome and course of illness is very easy to be recognized by means of the symptom, and (2) the symptom is statistically significantly correlated with this entity. In both definitions the schizophrenic nature of the single symptom remains undetermined. Here the attempt is made to work out a specificity of manic and depressive phenomena, a phenomenological determination of manic-depressive psychosis as an essential entity, respectively, by tracing structural signs of the moods and delusions as well as of the personality of manic-depressives. The same could be done in some way also with schizophrenic psychoses. We believe that only if we arrive at a clearer determination of what is meant by schizophrenic, manic, and depressive not only in a correlative statistical, but also in a phenomenological sense, we might have a chance finally to classify schizo-affective psychosis psychopathologically on an empirical basis.</p>","PeriodicalId":76382,"journal":{"name":"Psychiatria clinica","volume":"16 2-4","pages":"265-74"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000283975","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17678751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Phenomenology of abnormal body perceptions].","authors":"M L Schäfer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The present paper deals with the problematic nature of the phenomenological grasping of the consciousness of the body and its pathological modifications. The reasoning is oriented by the doctrine of Husserl of the so-called sentiments as the fundamentals of the experience of the own body. This basic approach does not only seem to be basically for a psychology of the consciousness of the body, but also to give the theoretical-conceptual structure for a great number of psychopathological modifications. Subsequent to a criticism of the conventional use of the term 'hallucination of the body' we attempt to chart elements of a scheme of the abnormal consciousness of the body.</p>","PeriodicalId":76382,"journal":{"name":"Psychiatria clinica","volume":"16 5-6","pages":"378-90"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17702672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Schanda, P Berner, E Gabriel, M L Kronberger, B Küfferle
{"title":"[Family picture studies in patients with paranoid psychoses].","authors":"H Schanda, P Berner, E Gabriel, M L Kronberger, B Küfferle","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Among the first-degree relatives of 77 patients with delusional functional psychoses the authors found 13 schizophrenics (3.10%), 8 manic-depressives (1.91%) and 14 cases with atypical psychoses (3.34%), following ICD-9 criteria. These figures were compared with the figures in the literature on the genetics of paranoid schizophrenics and nonschizophrenic paranoids, regarding the different composition of the samples. Subdivision of the original 77 patients, using the concept of the axial syndromes, was able to form two homogeneous subgroups of first-degree relatives: one with a schizophrenia prevalence of 6.52% (uncorrected) and without any manic-depressive secondary cases (endogenomorphic-schizophrenic axial syndrome) and another with a manic-depressive illness (MDI) prevalence of 6.58% (uncorrected) without any secondary cases with schizophrenia or atypical psychosis. The first-degree relatives of the patients with an 'organomorphic' axial syndrome (usually excluded in other studies) had an increased rate of manic-depressive secondary cases (3.57%, uncorrected) and the highest rate of atypical psychosis (7.14%) without any schizophrenics, according to the etiopathogenetic heterogeneity of this group. 37 of the 77 patients were not assignable to any of the axial syndromes. In the first-degree relatives of these patients--best comparable to Kendler's criteria for 'delusional disorder'--an increased rate of schizophrenics and atypical psychoses was found (3.59 and 3.08%, uncorrected); the figures for MDI were within normal limits. Our results suggest that the axial syndromes are a useful diagnostic instrument in identifying--from the genetic standpoint--in part very homogeneous subgroups. This allows the conclusion that they are indicators for hypothetical basic disturbances.</p>","PeriodicalId":76382,"journal":{"name":"Psychiatria clinica","volume":"16 5-6","pages":"391-404"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17702675","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Psychomotor performance of schizophrenic patients and long-term neuroleptic therapy].","authors":"W Burr, E Kaiser","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>15 patients diagnosed as schizophrenics (ICD 295) under long-term neuroleptic treatment were compared with 15 neurotic and normal persons concerning their ability at a psychomotor task. There was no difference between both groups; no correlation between performance and neuroleptic dosage was found. However, motoric coordination of a small group was impaired. The authors discuss several hypotheses referring to these findings.</p>","PeriodicalId":76382,"journal":{"name":"Psychiatria clinica","volume":"16 5-6","pages":"316-23"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17206481","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E D Peselow, D L Dunner, R R Fieve, S I Deutsch, M E Rubinstein
{"title":"Age of onset of affective illness.","authors":"E D Peselow, D L Dunner, R R Fieve, S I Deutsch, M E Rubinstein","doi":"10.1159/000283932","DOIUrl":"https://doi.org/10.1159/000283932","url":null,"abstract":"The age of onset of affective illness as measured by the initial psychiatric consultation for four affective subtypes was evaluated. Bipolar I (mean age = 28.00) and cyclothymics (mean age = 27.58) sought psychiatric consultation for their affective symptoms significantly earlier than unipolar patients (mean age = 34.69). Bipolar II patients (mean age = 31.54) sought psychiatric consultation at an age intermediate between bipolar I and unipolar patients. Male bipolar II patients sought psychiatric treatment significantly later than female bipolar II patients and there was a nonsignificant trend toward male cyclothymics initially seeking treatment later than female cyclothymics. In all, the range of age of onset for the four affective subtypes was quite wide suggesting that a patient was at risk for developing an affective disorder at any time from adolescence to the geriatric age range.","PeriodicalId":76382,"journal":{"name":"Psychiatria clinica","volume":"15 3","pages":"124-32"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000283932","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18148127","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}