Medical journal of Osaka University最新文献_第2页

Adenocarcinoma in the ascending colon of ACI strain rat foster bred by WF-Osaka female rat. WF-Osaka雌性大鼠培养的ACI株大鼠升结肠腺癌。

Medical journal of Osaka University Pub Date : 1991-03-01

M Miyamoto, K Saeki, Y Tani

{"title":"Adenocarcinoma in the ascending colon of ACI strain rat foster bred by WF-Osaka female rat.","authors":"M Miyamoto, K Saeki, Y Tani","doi":"","DOIUrl":"","url":null,"abstract":"We now keep HFRSV free WF-Osaka rats and ACI rats together in the separate three animal rooms (animal room 1, 2 and 3) and the incidence of colon carcinoma is still high on the WF-Osaka rats in animal room 1 with the high humidity. Two female ACI rats developed colon carcinomas in the ascending colon. The gross and the histological appearance of the colon carcinoma were completely the same as those of WF-Osaka rats. ACI and WF-Osaka rat strain together have been kept bred in neighborhood of each other in different racks in the identical animal room 1. To obtain HFRSV free ACI rat strain, Antecedents born by cesarean section of ACI female pregnant rat were foster-bred by WF-Osaka female nursing rat incidentally, and at the fourth mating generation after the start of foster-breeding, they developed colon carcinomas at the age of four months. Before five out of eight F1 hybrids by WF-Osaka cancer carrying female rat x male ACI rat had developed the same colon carcinoma, but none of F1 hybrids by the contrary mating had developed colon carcinomas in this same animal room 1. Animal room 1 and 2 where there was a high incidence of colon carcinomas, had happened to be kept moistened. However, after disinfection of these animal rooms, the animal room 2 and 3 occurred to be kept dried, and rats of WF-Osaka strain ceased to develop colon carcinomas in the animal room 2. Thereafter, animal room 2 and 3 were adjusted to be kept moistened again. Subsequently WF-Osaka rats in the animal room 2 began to have colon carcinomas in the ascending colon as before, but none of rats developed colon carcinomas in the animal room 3. Based on these findings, we consider that milk factor at the time of foster-breeding played an important role first and high moistened condition of the animal room resulted in promoting effect on colon carcinogenesis on ACI rats and WF-Osaka rats as well.","PeriodicalId":76134,"journal":{"name":"Medical journal of Osaka University","volume":"40 1-4","pages":"1-3"},"PeriodicalIF":0.0,"publicationDate":"1991-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12541827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histopathology of the temporal bones in thanatophoric dysplasia. 发育不良颞骨的组织病理学研究。

Medical journal of Osaka University Pub Date : 1991-03-01

M Sano, M Sakagami, T Harada, T Matsunaga, Y Tominaga, M Nakayama

引用次数: 0

Induced adenocarcinoma of the ascending colon on LE and Wistar/Shhi rats and virus like particles in the serum of colon cancer carrying WF rats. LE和Wistar/Shhi大鼠升结肠腺癌的诱导及携带WF的结肠癌大鼠血清中的病毒样颗粒。

Medical journal of Osaka University Pub Date : 1991-03-01

M Miyamoto, K Saeki, Y Tani, H Amano, T O Sodoh, H Nakao, T Konishi

引用次数: 0

Recurrence after incompletely resected acousticus neurinomas. 不完全切除听神经瘤后复发。

Medical journal of Osaka University Pub Date : 1991-03-01

S Sakaki, K Nakagawa, T Hatakeyama, Y Murakami, S Ohue, K Matsuoka

{"title":"Recurrence after incompletely resected acousticus neurinomas.","authors":"S Sakaki, K Nakagawa, T Hatakeyama, Y Murakami, S Ohue, K Matsuoka","doi":"","DOIUrl":"","url":null,"abstract":"It is known that the recurrence rate is high when an acoustic neurinoma is incompletely excised, but the details of the process of recurrence are still unclear. We reviewed the recurrence of acoustic neurinomas, as evaluated by computed tomography (CT) or magnetic resonance imaging (MRI), in 51 consecutive patients over the past 10 years who underwent tumor resection and had postoperative follow-up by CT or MRI. The factors promoting recurrence related to incomplete excision of tumor were analyzed. Total resection of the tumor was performed in 22 patients (43%), nearly total resection in 17 patients (33%) and subtotal resection in 12 patients (24%). The recurrence rates were 29% (5 of 17 patients) and 25% (2 of 8 patients) for nearly total and subtotal resection, respectively, whereas no recurrence occurred following total resection. Of the patients having nearly total resection, all recurrences arose from residual tumor in the internal auditory meatus (5 of 12 patients). In contrast, there were no recurrences from residual tumor at the site of the brain stem (none of 4 patients). Acoustic neurinomas should be totally removed through neurosurgical and neuro-otological approaches whenever possible. If a small fragment of tumor is left in the internal auditory meatus due to fear of damaging the facial or cochlear nerves, it should be strictly followed up by CT or MRI.","PeriodicalId":76134,"journal":{"name":"Medical journal of Osaka University","volume":"40 1-4","pages":"59-66"},"PeriodicalIF":0.0,"publicationDate":"1991-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12543113","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Initial appearance of an ill-defined shadow on a chest roentgenogram in a patient with aortitis syndrome. 主动脉炎综合征患者的胸片上最初出现一个模糊的阴影。

Medical journal of Osaka University Pub Date : 1991-03-01

S Imanaka, E Ueda, S Morimoto, T Ogihara, E Tsubura

引用次数: 0

In vivo evaluation of fixation of metal implants coated by melt-sprayed alumina--experiments in rabbit. 熔喷氧化铝涂层金属植入物的体内固定评价——家兔实验。

Medical journal of Osaka University Pub Date : 1991-03-01

T Fuji, K Fujiwara, Y Hirata, T Hijikata, S Saito, K Ono

引用次数: 0

Ultrasonographic monitoring of pancreatic pseudocyst during delivery. 分娩过程胰腺假性囊肿的超声监测。

Medical journal of Osaka University Pub Date : 1991-03-01

M Nakamuro, M Miyata, N Hatanaka, Y Ohtsuki, Y Kawashima

引用次数: 0

Effects of injection interval on pentylenetetrazol (PTZ) kindled seizures in rats. 注射间隔对戊四唑点燃大鼠癫痫发作的影响。

Medical journal of Osaka University Pub Date : 1991-03-01

J Ono, P D Walson

引用次数: 0

Demonstration of islet cell antibodies in apparently non-insulin dependent diabetic patients; a marker for the later development of insulin dependency. 非胰岛素依赖性糖尿病患者胰岛细胞抗体的检测这是胰岛素依赖后期发展的标志。

Medical journal of Osaka University Pub Date : 1991-03-01

H Katsura, N Itoh, T Hanafusa, N Kono, S Tarui

{"title":"Demonstration of islet cell antibodies in apparently non-insulin dependent diabetic patients; a marker for the later development of insulin dependency.","authors":"H Katsura, N Itoh, T Hanafusa, N Kono, S Tarui","doi":"","DOIUrl":"","url":null,"abstract":"One hundred and ten diabetic patients who were apparently non-insulin dependent at 1984 were followed up for 5 years from 1984 to 1989. Islet cell antibodies (ICA) of the patients were tested in 1987. Eleven patients were positive for ICA and 99 were negative. There was no significant difference in age, sex, duration of diabetes, and HbA1c levels between ICA-positive and negative groups. Six of 11 (54.5%) patients in ICA-positive group developed insulin-requiring state in the period from 1984 to 1989, while only 5 of 99 (5.1%) patients in ICA negative group became insulin-requiring. Glucagon tolerance test (1 mg i.v.) was performed on 8 patients who developed insulin-requiring state; among them 4 patients were ICA-positive and other 4 patients were ICA negative. The serum C-peptide response to intravenous glucagon injection was markedly decreased in 3 of the 4 ICA-positive patients, and only mildly decreased in all the 4 ICA-negative patients. The markedly decreased C-peptide response indicates that these ICA-positive subjects had developed insulin-dependency. We conclude that the presence of ICA in apparently non-insulin dependent diabetics indicates a high risk for developing insulin-dependency.","PeriodicalId":76134,"journal":{"name":"Medical journal of Osaka University","volume":"40 1-4","pages":"67-71"},"PeriodicalIF":0.0,"publicationDate":"1991-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12543114","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical and histologic study of endoscopic duodenitis. 内镜下十二指肠炎的临床及组织学研究。

Medical journal of Osaka University Pub Date : 1991-03-01

H Kawamoto, S Himeno, Y Shinomura, Y Sakamura, K Yamamoto, S Tarui

引用次数: 0