Medical journal of Osaka University最新文献_第3页

Demonstration of islet cell antibodies in apparently non-insulin dependent diabetic patients : a marker for the later development of insulin dependency 胰岛细胞抗体在明显非胰岛素依赖的糖尿病患者中的表现:胰岛素依赖后期发展的标志

Medical journal of Osaka University Pub Date : 1991-03-01 DOI: 10.11501/3054473

桂勇人

{"title":"Demonstration of islet cell antibodies in apparently non-insulin dependent diabetic patients : a marker for the later development of insulin dependency","authors":"桂勇人","doi":"10.11501/3054473","DOIUrl":"https://doi.org/10.11501/3054473","url":null,"abstract":"One hundred and ten diabetic patients who were apparently non-insulin dependent at 1984 were followed up for 5 years from 1984 to 1989. Islet cell antibodies (ICA) of the patients were tested in 1987. Eleven patients were positive for ICA and 99 were negative. There was no significant difference in age, sex, duration of diabetes, and HbA1c levels between ICA-positive and negative groups. Six of 11 (54.5%) patients in ICA-positive group developed insulin-requiring state in the period from 1984 to 1989, while only 5 of 99 (5.1%) patients in ICA negative group became insulin-requiring. Glucagon tolerance test (1 mg i.v.) was performed on 8 patients who developed insulin-requiring state; among them 4 patients were ICA-positive and other 4 patients were ICA negative. The serum C-peptide response to intravenous glucagon injection was markedly decreased in 3 of the 4 ICA-positive patients, and only mildly decreased in all the 4 ICA-negative patients. The markedly decreased C-peptide response indicates that these ICA-positive subjects had developed insulin-dependency. We conclude that the presence of ICA in apparently non-insulin dependent diabetics indicates a high risk for developing insulin-dependency.","PeriodicalId":76134,"journal":{"name":"Medical journal of Osaka University","volume":"40 1","pages":"67-71"},"PeriodicalIF":0.0,"publicationDate":"1991-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64430601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prediction of contractile reversibility in impaired left ventricular wall motion following coronary artery bypass grafting. 冠状动脉旁路移植术后左室壁运动受损的收缩可逆性预测。

Medical journal of Osaka University Pub Date : 1991-03-01

T Kobayashi, Y Fudemoto, T Yoshino, T Oda, K Fujimoto, H Hirose, Y Kawashima

{"title":"Prediction of contractile reversibility in impaired left ventricular wall motion following coronary artery bypass grafting.","authors":"T Kobayashi, Y Fudemoto, T Yoshino, T Oda, K Fujimoto, H Hirose, Y Kawashima","doi":"","DOIUrl":"","url":null,"abstract":"Interventional left vertriculograms (LVGs) using postextrasystolic potentiation (PESP), nitroglycerin (TNG) and a combination of both were analyzed in order to decide the degree of efficacy of each intervention as a predictor of reversibility in impaired left ventricular segments. Segmental wall motion (SWM) in less severely impaired segments increased to the normal range and SWM in severely impaired segments increased but remained in the abnormal range after CABG. The effects of both PESP and TNG on SWM in impaired segments correlated (r = 0.78 and 0.78) with that of CABG. The increase in SWM due to TNG + PESP was significantly (p < 0.01) greater than that due to either PESP or TNG alone or that of CABG. Either PESP or TNG was clinically reliable for prediction of contractile reversibility in the segments with impaired wall motion prior to CABG. Including the global left ventricular function, PESP reflected the efficacy of CABG more sufficiently than TNG. TNG + PESP provoked more contractile reserve and exaggerated the results of CABG, but may predict reversibility in severely reduced wall motion.","PeriodicalId":76134,"journal":{"name":"Medical journal of Osaka University","volume":"40 1-4","pages":"29-37"},"PeriodicalIF":0.0,"publicationDate":"1991-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12541831","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The CT evaluation of transcatheter arterial chemo-embolization, using iodized oil for hepatocellular carcinoma. 肝细胞癌经导管动脉碘化油化疗栓塞的CT评价。