Medecine interne最新文献_第5页

Contributions to the study of the favouring role of chronic urinary infections in inducing and starting drug-allergic-type reactions. 对慢性尿路感染在诱导和开始药物过敏型反应中的有利作用的研究贡献。

Medecine interne Pub Date : 1990-01-01

I B Iamandescu

{"title":"Contributions to the study of the favouring role of chronic urinary infections in inducing and starting drug-allergic-type reactions.","authors":"I B Iamandescu","doi":"","DOIUrl":"","url":null,"abstract":"A randomized study in a group of 87 patients with drug-allergic-type reactions (DAtR) manifested by urticaria and or angioedema, revealed in 55 patients (63.2%) the presence of chronic urinary infections (CUI), significantly different (p less than 0.001) from the control group (80 patients without DAtR) in which the incidence of CUI was only 20% (16 patients). Among the drugs observed to induce allergic-type reactions were substances such as penicillins and aspirin which are not used in CUI. It was therefore assumed that it is not their frequent use in CUI (as is the case with antibacterial drugs and contrast iodide substances) that leads to DAtR but rather more the CUI proper. The assumption that CUI are risk factors for the occurrence of DAtR is discussed and the following mechanisms are suggested in support of this assumption: enhancement of IgE secretion (by the drugs as allergens--complete or haptens--or by the inhibiting effects of some antibiotics on the T suppressor cells): nonimmunological mast cell degranulation (by the bacterial wall products--lectins and proteoglycans--or by the endotoxines with complement activation generating anaphylatoxines C3a and C5a): neurovegetative changes induced by infectious diseases.","PeriodicalId":76129,"journal":{"name":"Medecine interne","volume":"28 1","pages":"53-60"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13434282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical studies on alpha 2 plasmin inhibitor. α - 2纤溶酶抑制剂的临床研究。

Medecine interne Pub Date : 1990-01-01

S Roman, O Knauer, M Cucuianu

{"title":"Clinical studies on alpha 2 plasmin inhibitor.","authors":"S Roman, O Knauer, M Cucuianu","doi":"","DOIUrl":"","url":null,"abstract":"Plasma levels of alpha 2 plasmin inhibitor (alpha 2 PI) were measured by both an immunological and a functional assay, and a good correlation (r = 0.793; p less than 0.001) was found between the two methods. When compared to values recorded in 17 control subjects (69.55 micrograms/ml +/- 2.04) alpha 2 PI antigen levels were found to be obviously decreased in the 10 patients with decompensated cirrhosis of the liver (41.06 micrograms/ml +/- 4.66) and slightly increased in the 13 nephrotic patients (79.73 micrograms/ml +/- 2.35) and in the 23 hypertriglyceridemic and obese patients (78.59 micrograms/ml +/- 2.23). In spite of similar plasma levels of alpha 2 PI, dilute blood clot lysis was rather accelerated in patients with the nephrotic syndrome (240 min +/- 12) and obviously delayed in patients with endogenous hypertriglyceridemia (739 min +/- 131). Apparently the rate of clot lysis is mainly determined at an earlier stage of the fibrinolytic process, represented by the balance between tissue plasminogen activator and its inhibitor. Severe decrease of alpha 2 PI may nevertheless contribute to accelerated clot lysis as noted in a patient with familial heterozygous alpha 2 PI deficiency. On the other hand increased level of factor XIII and alpha 2 PI associated to an impaired plasminogen activation would render the fibrin network more resistant to fibrinolysis.","PeriodicalId":76129,"journal":{"name":"Medecine interne","volume":"28 1","pages":"73-81"},"PeriodicalIF":0.0,"publicationDate":"1990-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13281306","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bacterial immunofluorescence in the intestinal juice of patients with nonspecific chronic enteropathy. 非特异性慢性肠病患者肠液中的细菌免疫荧光。

Medecine interne Pub Date : 1990-01-01

G Gluhovschi, N Barbu, M Drăgan, A Schiller, M Tereteanu, I Sporea, N Csaki

引用次数: 0

In memoriam Constantin Velican, MD., Ph. D., D. Sci. 1919-1989. 为了纪念康斯坦丁·维利肯，医学博士，科学博士，1919-1989。

Medecine interne Pub Date : 1990-01-01

引用次数: 0

Early influence of ultrasonographic examination of the abdominal cavity on the concentration of the lipid system parameters in blood serum of healthy people. 早期腹腔超声检查对健康人血清脂质系统参数浓度的影响。