Alexandria Journal of Medicine最新文献

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Breast lesions and cancer: histopathology and molecular classification in a referral hospital in Ghana 乳腺病变和癌症:加纳转诊医院的组织病理学和分子分类
IF 0.9
Alexandria Journal of Medicine Pub Date : 2021-01-01 DOI: 10.1080/20905068.2021.1907960
N. Titiloye, K. Bedu-Addo, E. Manu, C. Ameh-Mensah, Foster Opoku, B. Duduyemi
{"title":"Breast lesions and cancer: histopathology and molecular classification in a referral hospital in Ghana","authors":"N. Titiloye, K. Bedu-Addo, E. Manu, C. Ameh-Mensah, Foster Opoku, B. Duduyemi","doi":"10.1080/20905068.2021.1907960","DOIUrl":"https://doi.org/10.1080/20905068.2021.1907960","url":null,"abstract":"ABSTRACT Background: Histological diagnosis is crucial to the management of breast diseases. It determines the kind of disease, the treatment modalities, and the outcome of management. Our department receives breast biopsies from the northern sector of Ghana constituting over 50% of the Ghanaian population. This study aimed at elucidating the pattern of disease and associated traditional prognostic indices of breast cases in our department over a period of 9 years. Methods: Information on the demographic characteristics and the histological diagnoses made on all breast cases received and processed in the department were accessed and entered into an Excel spreadsheet. Slides were reviewed and IHC was done on suitable cases. Descriptive statistics were generated using IMB-SPSS version 23. Results: A total of 4276 breast cases were received by the department within the study period, with 97.6% being female. Age ranged (female/male) from 10 to 98/13 to 102 years, with mean ages of 38.2 years (SD ± 16.7) and 41.15 years (SD ± 21.6), respectively. Cases were evenly distributed in both left and right breasts and 4.3% were bilateral. Inflammatory conditions were seen in 7.5% of cases. The most diagnosed benign tumor was fibroadenoma (54%), followed by fibrocystic change (8.1%). Gynecomastia was diagnosed in 66.3% of males. Malignant cases were 38.6%, with invasive carcinoma NST being the most frequent (87.5%). Histological grades were I = 9.4%, II = 41.6%, and III = 49%. Molecular subtypes were luminal A (19.8%), luminal B (9.9%), Her2 (16%), and TNBC (54.3%). Conclusion: Our findings show an increase in breast cancer cases compared to previous studies in our center, suggesting increased awareness and improved diagnosis. However, this increase is consistent with most studies in sub-Saharan Africa.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"130 - 136"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20905068.2021.1907960","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47100545","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Oxidative protein modification and chromosomal instability among type 2 diabetics in Osogbo, Nigeria 氧化蛋白修饰和染色体不稳定性在2型糖尿病患者Osogbo,尼日利亚
IF 0.9
Alexandria Journal of Medicine Pub Date : 2021-01-01 DOI: 10.1080/20905068.2021.1935123
Olaniyan O.O, O. Odewusi, H. Osadolor
{"title":"Oxidative protein modification and chromosomal instability among type 2 diabetics in Osogbo, Nigeria","authors":"Olaniyan O.O, O. Odewusi, H. Osadolor","doi":"10.1080/20905068.2021.1935123","DOIUrl":"https://doi.org/10.1080/20905068.2021.1935123","url":null,"abstract":"ABSTRACT Background: The abundance of proteins in human system has made it a major target for glucose auto-oxidation. Likewise, chromosomal instability, describes an oxidative DNA damage that can be accelerated by chronic hyperglycemia. This work investigates the extent and contribution of diabetes oxidation/stress on protein carbonylation and chromosomal instability among 120 type 2 diabetics (60 with vascular complications and 60 without any vascular complications) and 50 apparently healthy control subjects. Anthropometric data and fasting venous blood specimen was collected from each participant for glyceamic control, antioxidants, protein oxidation, oxidative DNA damage parameters and chromosomal aberration assay using standard methods. Results: Diabetics without vascular complications shows a significant (p = 0.0000) difference in all measured parameters except 8-OHdG (p = 0.0764) as compared to control subjects. However, diabetics with vascular complications show significant (p = 0.0000) difference of all measured parameters than those without vascular complications. Conclusion: Our study findings indicate an increased formation of protein carbonyl contents, and chromosomal aberration in diabetics especially among those with vascular complications, likewise, diabetes with vascular complications is associated with increased DM disease activity. Thus, protein oxidative biomarker can serve as a therapeutic tool in the management of diabetes cases while increased chromosomal aberration may indicate an increased risk for cancer among diabetics.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"168 - 176"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20905068.2021.1935123","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46070716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Occupational formaldehyde exposure linked to increased systemic health impairments and counteracting beneficial effects of selected antioxidants 职业性甲醛暴露与系统健康损害增加有关,并抵消所选抗氧化剂的有益作用
IF 0.9
Alexandria Journal of Medicine Pub Date : 2021-01-01 DOI: 10.1080/20905068.2021.1926172
S. Tesfaye, N. Hamba, Asfaw Gerbi, Zenebe Negeri
{"title":"Occupational formaldehyde exposure linked to increased systemic health impairments and counteracting beneficial effects of selected antioxidants","authors":"S. Tesfaye, N. Hamba, Asfaw Gerbi, Zenebe Negeri","doi":"10.1080/20905068.2021.1926172","DOIUrl":"https://doi.org/10.1080/20905068.2021.1926172","url":null,"abstract":"ABSTRACT Background: Formaldehyde (FA) is a sensitizing agent that can produce an effective immune system response upon initial exposure. FA that can be used in many industries, medical and anatomical facilities, mainly cadaver-based gross anatomy laboratories, represent a risk to occupational health of professionals and students. The majority of FA exposures occur through inhalation, dermal, and eye contact. FA-induced effects are attributed to site-specific and dose-dependent health impairments in many organs and organ systems. Much progress has been reported on FA-induced health impairments in respiratory tract, but a comprehensive study in different organ systems and the reverse effects of some novel antioxidants is still lacking. This review explores the cytotoxic effects of FA and its role as key signaling molecule, site specific and or dose dependent effects of FA in nasal cavity, carcinogenic effects of FA exposure in nasopharynx, effects of FA in lung macrophage functions and development of pulmonary fibrosis, dose dependent reproductive and genetic effects of FA, neurotoxic effects of FA and potential risk of FA in some beauty salons and cosmetic products. In addition, this study shows the counteracting beneficial role of melatonin, Nigella sativa, rose oils, caffeic acid phenethyl ester (CAPE), vitamin E, and proanthocyanidins (PAs) against FA induced tissue damage.Methods: A comprehensive literature search highlighting the health impairments of FA and counteracting beneficial effects of promising antioxidants was conducted using PubMed, Google Scholar, and Medline Cochrane, to assemble relevant publications from open access international journals published only in English.Results: The search generated 411 articles of which 70 full research articles fulfilled the inclusion criteria and included in the review. The results of this study confirmed relentless toxic effects of FA exposure on various organs of human and other animals. Multiple findings also stated the efficacy of promising antioxidants against FA-induced tissue damage in animal models.Conclusion: Occupational exposure to FA is most likely due to inattention towards its side effects and lack of appropriate air filtering equipment or unmonitored concentration of FA in the working air. Therefore, re-evaluating the concentration of FA, proper ventilation, and assessment of working practices is highly recommended. Proper monitoring is also needed to improve compliance and protection of FA-based reproductive complications in females. Despite complete prevention is not viable, exposed personnel must be aware of FA-induced health effects and require assessing risks and acquiring practical measures in their working environment.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"157 - 167"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20905068.2021.1926172","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44075787","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Comparative study between fisher anatomical subunit approximation technique and millard rotation- advancement technique in unilateral cleft lip repair fisher解剖亚单位近似技术与millard旋转推进技术在单侧唇裂修复中的比较研究
IF 0.9
Alexandria Journal of Medicine Pub Date : 2021-01-01 DOI: 10.1080/20905068.2021.1885954
Mohamed F. ElMaghraby, Nasser A. Ghozlan, M. Ashry, Mohamed H Abouarab, A. Farouk
{"title":"Comparative study between fisher anatomical subunit approximation technique and millard rotation- advancement technique in unilateral cleft lip repair","authors":"Mohamed F. ElMaghraby, Nasser A. Ghozlan, M. Ashry, Mohamed H Abouarab, A. Farouk","doi":"10.1080/20905068.2021.1885954","DOIUrl":"https://doi.org/10.1080/20905068.2021.1885954","url":null,"abstract":"ABSTRACT Introduction: The ideal lip repair is characterized by; the symmetrical shape of nasolabial folds and both alae of the nose with a natural-looking philtrum and Cupid’s bow in both static and dynamic states, in addition to a hidden scar. Objective: to compare between Fisher anatomical subunit approximation technique and Millard rotational advancement technique in unilateral cleft lip repair. Methods: Prospective study for 40 patients presented to Alexandria Main University hospital with unilateral cleft lip deformity between March 2019 and October 2020. Twenty patients with unilateral cleft lip deformity were repaired by Fisher anatomical subunit approximation technique, while the other twenty were repaired by Millard rotational-advancement technique. The postoperative photographs of the patients were captured and processed in computer photogrammetry software through which anthropometric parameters including (lip height, lip width, vermilion height, and alar base width) were compared between the normal side and the repaired side. In this software, each anthropometric parameter length on the normal side is taken as a control with a fixed value of (1) then the same parameter on the repaired side was measured as a ratio of this value to avoid bias. Comparison between both groups for assessment of the quality of cleft lip repair was also done based on Steffensen grading criteria. Results: Comparison between both techniques in unilateral cleft lip repair showed that there was no significant difference between them in the anthropometric measurements. While the comparison between the two groups using Steffensen grading criteria showed that Fisher’s technique surpassed Millard’s technique. Conclusion: We recommend the use of the Fisher anatomical subunit approximation technique in unilateral cleft lip repair for its superior results over the Millard rotational advancement technique.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"92 - 102"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20905068.2021.1885954","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46773216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 7
EFFECT OF PROGESTRONE IN PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY 黄体酮在重型颅脑外伤患者中的作用
IF 0.9
Alexandria Journal of Medicine Pub Date : 2021-01-01 DOI: 10.1080/20905068.2021.1880041
A. Dahroug, T. Zaytoun, Mahmoud Salah Anwar Hussien
{"title":"EFFECT OF PROGESTRONE IN PATIENTS WITH SEVERE TRAUMATIC BRAIN INJURY","authors":"A. Dahroug, T. Zaytoun, Mahmoud Salah Anwar Hussien","doi":"10.1080/20905068.2021.1880041","DOIUrl":"https://doi.org/10.1080/20905068.2021.1880041","url":null,"abstract":"ABSTRACT Background: Traumatic brain injury is a major public health concern, resulting in substantial mortality and long-term disability. So, it was important to search for novel therapeutic modalities that play an important role in reducing cerebral edema and had neuro- protective effect. A number of studies showed the feasibility, safety, and effectiveness of early parenteral administration of progesterone in acute severe traumatic brain injury patients compared with standard care. Objective: The study aimed to assess the effect of the progesterone on the neurologic outcome in non-operable patients with acute severe traumatic brain injury. Patients and Methods: This study was conducted on 50 patients presented with severe traumatic brain injury with GCS less than or equal to 8 after resuscitation and stabilization including both sexes. They were categorized into two groups according to applying the progesterone protocol. Patients were subjected to informed consent from next of kin, history taking, clinical neurological examination, routine laboratory and radiological investigations as needed and progesterone administration to patients in group 2which was given intramuscularly in dose of 1 mg/kg every12h for 7 consecutive days. Results: Early parenteral administration of progesterone was associated with significant decrease in the mortality rate at day 28, significant improvement in Glasgow outcome scale of the patients by the end of day 28, significant improvement in level of consciousness of the patients (GCS), SOFA score, and CT brain Marshall scoring. Conclusion: Progesterone administration in acute severe traumatic brain injury patients was associated with significant decrease in 28th day mortality, period of ICU stay, and mechanical ventilation days. Also, it was feasible and safe without noted complications.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"75 - 81"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20905068.2021.1880041","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47598107","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Correlation between Micronutrient plasma concentration and disease severity in COVID-19 patients 新型冠状病毒肺炎患者血浆微量营养素浓度与病情严重程度的相关性
IF 0.9
Alexandria Journal of Medicine Pub Date : 2021-01-01 DOI: 10.1080/20905068.2020.1870788
A. Alkattan, K. Alabdulkareem, A. Kamel, Heba Abdelseed, Yousef S Almutairi, E. Alsalameen
{"title":"Correlation between Micronutrient plasma concentration and disease severity in COVID-19 patients","authors":"A. Alkattan, K. Alabdulkareem, A. Kamel, Heba Abdelseed, Yousef S Almutairi, E. Alsalameen","doi":"10.1080/20905068.2020.1870788","DOIUrl":"https://doi.org/10.1080/20905068.2020.1870788","url":null,"abstract":"ABSTRACT Objectives Coronavirus Disease 2019 (COVID-19) is caused by a new strain of betacoronavirus called SARS-CoV-2, which leads to mild to severe symptoms. Micronutrients in blood serum, namely, zinc, iron, copper, and selenium, play essential roles in the human body’s various organs. This study investigates the association between micronutrient levels and the severity of symptoms in SARS-CoV-2 infected patients. Methods A cross-section study was conducted during June–August 2020 in Riyadh city among 80 patients with confirmed SARS-CoV-2 infection. Within 24 hours of hospital admission, patients have been divided into non-severe and severe cases, and blood samples were drawn from each patient to measure the serum levels of copper, iron “in the form of ferritin,” selenium, and zinc. Results In both study groups, the mean copper and selenium serum levels were within the normal range, while the mean zinc and iron serum levels were elevated. A statistically significant difference was recorded between non-severe and severe cases regarding serum levels of iron and selenium (331.24 vs. 1174.95 ng/ml and 134 vs. 162 mcg/L, respectively, P < 0.0001). On the other hand, no significant difference was detected between both studied groups regarding serum level of zinc and copper (124.57 vs. 116.37 mcq/L and 18.35 vs. 18.2 mcmol/L, respectively, P > 0.05). Conclusions There was a significant elevation of selenium and iron serum levels among severe cases compared to non-severe cases of COVID-19. High levels of iron and selenium could be correlated with the disease severity during infection with SARS-CoV-2.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"21 - 27"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20905068.2020.1870788","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42739604","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Evaluation of Helicobacter pylori infection as a potential risk factor of acute ischemic cerebrovascular stroke 幽门螺杆菌感染作为急性缺血性脑血管卒中潜在危险因素的评价
IF 0.9
Alexandria Journal of Medicine Pub Date : 2021-01-01 DOI: 10.1080/20905068.2021.1990550
Ahmed A. Elhadidy, M. A. Basiouny
{"title":"Evaluation of Helicobacter pylori infection as a potential risk factor of acute ischemic cerebrovascular stroke","authors":"Ahmed A. Elhadidy, M. A. Basiouny","doi":"10.1080/20905068.2021.1990550","DOIUrl":"https://doi.org/10.1080/20905068.2021.1990550","url":null,"abstract":"ABSTRACT Background Helicobacter pylori (H. pylori) is a very common gastrointestinal infection that varies clinically from asymptomatic to overt peptic ulcer disease. Although H. pylori had been linked to ischemic heart disease, still scanty of data available about H. pylori link to ischemic cerebrovascular stroke. Object Evaluation of H. pylori Infection as a Potential Risk Factor of Acute Ischemic Cerebrovascular stroke. Method In a case control study, we recruited 150 ischemic stroke patients (group A) further subdivided into two subgroups atherosclerotic ischemic stroke (group A1) and cardioembolic stroke (group A2), also asymptomatic 95 patients recruited as non-ischemic control group (group B). All subjects were investigated for chronic H. pylori infection using both serum H. pylori IgG antibody test and urea breath test. Statistical analysis was done for obtained data. Results Significant higher prevalence of H. pylori infection was found among atherosclerotic stroke group (group A1) 61.4% versus non atherosclerotic group (A2) 40% and control group (B) 35.8% (P value 0.003), furthermore, significant higher prevalence when comparing group A1 (atherosclerotic stroke) and control group B (P1 value 0.001), still non-significant higher prevalence when comparing group A2 (cardio embolic stroke group) and control group B (P2 value 0.618). Conclusion Chronic H. pylori infection is a curable potential risk factor for ischemic atherosclerotic stroke. However, further studies needed to investigate the beneficial effect of H. pylori treatment on ischemic stroke.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"230 - 234"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45350440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
DO VITAMIN D DEFICIENCY AND HEPATITIS C VIRUS INFECTION PLAY A ROLE IN OXIDATIVE STRESS IN PATIENTS ON MAINTENANCE HEMODIALYSIS? 维生素D缺乏和丙型肝炎病毒感染在维持性血液透析患者的氧化应激中起作用吗?
IF 0.9
Alexandria Journal of Medicine Pub Date : 2021-01-01 DOI: 10.1080/20905068.2021.1956831
Mahmoud S. Abdelhady, Sara T Ibrahim, Ahmed Adam, Abelaziz Elnekidy, Neveen Lewis, Rasha Ibrahim Gawesh
{"title":"DO VITAMIN D DEFICIENCY AND HEPATITIS C VIRUS INFECTION PLAY A ROLE IN OXIDATIVE STRESS IN PATIENTS ON MAINTENANCE HEMODIALYSIS?","authors":"Mahmoud S. Abdelhady, Sara T Ibrahim, Ahmed Adam, Abelaziz Elnekidy, Neveen Lewis, Rasha Ibrahim Gawesh","doi":"10.1080/20905068.2021.1956831","DOIUrl":"https://doi.org/10.1080/20905068.2021.1956831","url":null,"abstract":"ABSTRACT Background Elevated oxidant levels and low antioxidant levels in patients with end-stage renal disease (ESRD) play a significant role in the development of endothelial dysfunction, atherogenesis and cardiovascular disease (CVD). A deficiency in vitamin D (Vit.D) is also suggested to be responsible for the generation of oxidative stress (OS) and CVD. Among dialysis patients, conflicting data exist concerning the relationship between hepatitis C virus (HCV) infection and OS. We studied the relationship between 25Vit.D level, HCV infection, and plasma 8 iso-prostaglandin F2 α (8-ISO-PGF2α) as an OS marker in an Egyptian hemodialysis (HD) cohort. Methods One hundred and twenty ESRD patients on HD were initially recruited to the study but only 88 patients have met the inclusion and none of the exclusion criteria. Midweek predialysis session blood samples were collected for the measurement of 25(OH) Vit.D, plasma 8-ISO-PGF2α, high sensitivity C – reactive protein (hs-CRP), and intact parathyroid hormone (intact PTH). Patients were stratified into two groups according to the presence or absence of serum antibodies against HCV and their plasma 8-ISO-PGF2α were compared. Results Vit.D deficiency was noted in 93% of the participants; the median 8-ISO-PGF2α level was 382 pg/mL. No significant correlation between Vit.D and 8-ISO-PGF2α levels was found. Thirty-two participants (36%) were HCV+ and their 8-ISO-PGF2α levels were significantly lower relative to in the seronegative group (median 171 vs. 647 pg/mL; P < 0.006). Conclusion In this Egyptian HD cohort, Vit D deficiency was highly prevalent, yet failed to show any correlation with F2-isoprostanes. HCV+ HD patients might be shielded from OS.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"260 - 266"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48526240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Medical students’ attitudes towards patient-centered care, Fayoum Medical School, Egypt 医学生对以患者为中心的护理的态度,埃及法尤姆医学院
IF 0.9
Alexandria Journal of Medicine Pub Date : 2021-01-01 DOI: 10.1080/20905068.2021.1936420
N. El-Sherbiny, Eman H. Ibrahim, Nashwa Sayed
{"title":"Medical students’ attitudes towards patient-centered care, Fayoum Medical School, Egypt","authors":"N. El-Sherbiny, Eman H. Ibrahim, Nashwa Sayed","doi":"10.1080/20905068.2021.1936420","DOIUrl":"https://doi.org/10.1080/20905068.2021.1936420","url":null,"abstract":"ABSTRACT Background: Patient-centered care has been considered the foundation of healthcare quality and the core competency of the doctor-patient relationship. Aims: To assess the attitudes of medical students toward a patient-centered approach and identify the predictors of patient-centeredness scores. Methods: A cross-sectional study was carried out in Fayoum Medical School/Egypt using a validated Arabic version of the Patient-Practitioner Orientation Scale (PPOS). Results: The total PPOS score showed variable score as the grades move up. The total PPOS ranged from 0.05 to 4.39 with an average score of (2.71 ± 0.66) for the entire sample. The sharing and caring subscale score ranged from 0.56 to 4.44 and 0.44 to 5.33 with an average score of (2.33 ± 0.49) and (3.09 ± 0.92) respectively. Conclusion: Medical students had low patient-centered attitude. Medical curricula should be redesigned, and medical students may also benefit from engagement in patient healthcare service.","PeriodicalId":7611,"journal":{"name":"Alexandria Journal of Medicine","volume":"57 1","pages":"188 - 193"},"PeriodicalIF":0.9,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1080/20905068.2021.1936420","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48627563","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Antimicrobials associated adverse drug reaction profiling: a four years retrospective study (Pharmacovigilance study) 抗菌药物相关不良反应分析:一项为期四年的回顾性研究(药物警戒研究)
IF 0.9
Alexandria Journal of Medicine Pub Date : 2021-01-01 DOI: 10.1080/20905068.2021.1938425
M. Agrawal, Preeti Singh, Usha Joshi
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