Le Poumon et le coeur最新文献_第8页

[Pulmonary carbon monoxide exchange constants in the "stable state" at rest in healthy non-smokers]. [健康非吸烟者静止时肺一氧化碳交换常数处于“稳定状态”]。

Le Poumon et le coeur Pub Date : 1982-03-01

J Bréant, M F Fleury, A Vanlerberghe, S Maurique, F Roulland

{"title":"[Pulmonary carbon monoxide exchange constants in the \"stable state\" at rest in healthy non-smokers].","authors":"J Bréant, M F Fleury, A Vanlerberghe, S Maurique, F Roulland","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>During simultaneous evaluation of pulmonary O2, CO2, and CO in the stable state (ES) at rest, CO volume per minute (V'CO) standardized (V'COs) for FICO = 0.001 [2, 3] can be expressed relative to simultaneous flow of \"respiratory\" gases (V'O2 and V'CO2) by the quotient of the gas concentrations concerned, if its is admitted that V'I = V'E. Whether at the \"expired\"mean E or \"alveolar\" A levels, these concentrations have identical paired relationships. In the strict stable state, the proposed expressions of V'CO are constants independent of age, sex, stature, and ventilatory regimen in healthy non-smokers [6]; the result is that V'COs in relation to alveolar ventilation, V'COs/V'A, which is related to V'COs/V'CO2 by PaCO2, is also a constant. When the so-called \"stable\" state is not a strict one, experimental arguments suggest that V'COs/V'CO2 alone is not markedly influenced by ventilatory instability. Measurements conducted by means of different biological modalities and techniques in 3 groups of healthy women of homogeneous age breathing in a semi-open circuit: 1) established the value of the constants V'COs/V'CO2, V'COs/V'O2, V'COs/V'A in the true stable state (ESV) controlled by R and by gasometry on simultaneously collected blood samples; and 2) confirmed the constant character of V'COs/V'CO2 whatever the degree of respiratory stabilization, even when the ventilatory regimen was in reality not stabilised (ENS); V'COs/V'CO2 should therefore be the only value for defining a \"specific capacity of pulmonary CO exchange\". V'COs/V'A appears to be related to Q'/V'A. As DuCO/(DuCO2.1,21), which measures this ratio, it is independent of age and of ventilatory frequency. Several facts indicate that the \"parallelism\" of modifications affecting DuCO and DuCO2 [15] is not found in all physiological and pathological circumstances.</p>","PeriodicalId":76107,"journal":{"name":"Le Poumon et le coeur","volume":" ","pages":"69-81"},"PeriodicalIF":0.0,"publicationDate":"1982-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40494499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}