La Ricerca in clinica e in laboratorio最新文献

Observational Study on the Effect of Duration from Pediatric Advanced Life Support (PALS) Certification on PALS Performance in Pediatric Interns in Simulated Cardiopulmonary Arrest. 小儿高级生命支持(PALS)认证时间对模拟心肺骤停儿科实习生PALS表现影响的观察性研究。

IF 0.7

La Ricerca in clinica e in laboratorio Pub Date : 2021-07-08 eCollection Date: 2023-12-01 DOI: 10.1055/s-0041-1731787

Nancy M Tofil, Stacy L Gaither, Charli Cohen, Carrie Norwood, Jerry Lynn Zinkan, Sai S Raju, Chrystal Rutledge

{"title":"Observational Study on the Effect of Duration from Pediatric Advanced Life Support (PALS) Certification on PALS Performance in Pediatric Interns in Simulated Cardiopulmonary Arrest.","authors":"Nancy M Tofil, Stacy L Gaither, Charli Cohen, Carrie Norwood, Jerry Lynn Zinkan, Sai S Raju, Chrystal Rutledge","doi":"10.1055/s-0041-1731787","DOIUrl":"10.1055/s-0041-1731787","url":null,"abstract":"Pediatric advanced life support (PALS) training is critical for pediatric residents. It is unclear how well PALS skills are developed during this course or maintained overtime. This study evaluated PALS skills of pediatric interns using a validated PALS performance score following their initial PALS certification. All pediatric interns were invited to a 45-minute rapid cycle deliberate practice (RCDP) training session following their initial PALS certification from July 2017 to June 2019. The PALS score and times for key events were recorded for participants prior to RCDP training. We then compared performance scores for those who took PALS ≥3 months, between 3 days to 3 months and 3 days after PALS. There were 72 participants, 30 (of 30) in 3 days, 18 in 3 days to 3 months, and 24 in ≥3 months groups (42 total of 52 residents, 81%). The average PALS performance score was 53 ± 20%. There was no significant difference between the groups (3 days, 53 ± 15%; 3 days-3 months, 51 ± 19%; ≥3 months, 54 ± 26%, p = 0.922). Chest compressions started later in the ≥3 months groups compared with the 3 days or ≤3 months groups ( p = 0.036). Time to defibrillation was longer in the 3 days group than the other groups ( p = 0.008). Defibrillation was asked for in 3 days group at 97%, 73% in 3 days to 3 months and 68% in ≥3 months groups. PALS performance skills were poor in pediatric interns after PALS certification and was unchanged regardless of when training occurred. Our study supports the importance of supplemental resuscitation training in addition to the traditional PALS course.","PeriodicalId":76092,"journal":{"name":"La Ricerca in clinica e in laboratorio","volume":"1 1","pages":"271-277"},"PeriodicalIF":0.7,"publicationDate":"2021-07-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10631835/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73463574","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Reviews of book 书评

La Ricerca in clinica e in laboratorio Pub Date : 2021-02-08 DOI: 10.1007/BF03054705

B. C.D., D. F.

引用次数: 0

[Thymosin]. [胸腺素]。

La Ricerca in clinica e in laboratorio Pub Date : 2020-02-07 DOI: 10.32388/1bqvgp

F. Dammacco

引用次数: 4

Liver system. IV. More on the liver micro-unit: physics and geometry of its action. 肝脏系统。更多关于肝脏微单位:其作用的物理和几何。

La Ricerca in clinica e in laboratorio Pub Date : 1991-01-01 DOI: 10.1007/BF02919113

N Dioguardi

引用次数: 1

Time sequence of coagulation data in patients with decompensated liver cirrhosis and suspected disseminated intravascular coagulation. 失代偿期肝硬化疑似弥散性血管内凝血患者凝血数据的时间顺序。

La Ricerca in clinica e in laboratorio Pub Date : 1991-01-01 DOI: 10.1007/BF02919119

G Cioni, A Cristani, E Tincani, P Ventura, G Zagni, E Ventura

{"title":"Time sequence of coagulation data in patients with decompensated liver cirrhosis and suspected disseminated intravascular coagulation.","authors":"G Cioni, A Cristani, E Tincani, P Ventura, G Zagni, E Ventura","doi":"10.1007/BF02919119","DOIUrl":"https://doi.org/10.1007/BF02919119","url":null,"abstract":"In patients with liver cirrhosis, especially in the advanced stage, the coexistence of low clotting factor levels, hypofibrinogenemia, thrombocytopenia and elevated fibrin(ogen) degradation product (FDP) and D-dimer levels may suggest the presence of disseminated intravascular coagulation (DIC). In this study we evaluated, in 21 patients with decompensated liver cirrhosis and elevated FDP and D-dimer levels, the time sequence of their coagulation data during a follow-up period of 15 days after the first observation; our aim was to clarify if these patients tend to develop during this time interval a severe consumption coagulopathy as an expression of overt DIC. We evaluated serum fibrinogen, platelet count, prothrombin activity, serum FDP and plasma D-dimer levels at days 1, 3, 6, 10 and 15. The coagulation data were fairly stable during the study period in all patients, even in the two patients who had upper digestive tract bleeding during the study time. Only two patients affected by infectious diseases showed a decrease of D-dimer and FDP levels after healing. Our data suggest that in decompensated liver cirrhosis the detection of elevated FDP and D-dimer levels is seldom related to the occurrence of an overt DIC, at least during a short time interval; in this condition heparin therapy seems therefore not advisable and even potentially dangerous.","PeriodicalId":76092,"journal":{"name":"La Ricerca in clinica e in laboratorio","volume":"21 1","pages":"105-9"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02919119","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13027380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Increase of plasma tissue-plasminogen activator antigen levels after induced abortion. 人工流产后血浆组织-纤溶酶原激活物抗原水平升高。

La Ricerca in clinica e in laboratorio Pub Date : 1991-01-01 DOI: 10.1007/BF02919117

T Yoshimura, T Nakamura, M Ito, N Kawasaki, H Okamura

引用次数: 0

What roles have anti-interferon antibodies in physiology and pathology? 抗干扰素抗体在生理和病理上有什么作用?

La Ricerca in clinica e in laboratorio Pub Date : 1991-01-01 DOI: 10.1007/BF02919115

V Bocci

引用次数: 3

The functioning liver mass. 功能正常的肝块。

La Ricerca in clinica e in laboratorio Pub Date : 1991-01-01 DOI: 10.1007/BF02919112

G Molino

引用次数: 5

In vitro infection with HIV of antigen-specific T cell clones derived from HIV-seronegative individuals. Effects on cytokine production and helper function. 来自HIV血清阴性个体的抗原特异性T细胞克隆在体外感染HIV。对细胞因子产生和辅助功能的影响。

La Ricerca in clinica e in laboratorio Pub Date : 1991-01-01 DOI: 10.1007/BF02919116

D Macchia, C Simonelli, P Parronchi, M P Piccinni, P Biswas, M Mazzetti, A Ravina, E Maggi, S Romagnani

{"title":"In vitro infection with HIV of antigen-specific T cell clones derived from HIV-seronegative individuals. Effects on cytokine production and helper function.","authors":"D Macchia, C Simonelli, P Parronchi, M P Piccinni, P Biswas, M Mazzetti, A Ravina, E Maggi, S Romagnani","doi":"10.1007/BF02919116","DOIUrl":"https://doi.org/10.1007/BF02919116","url":null,"abstract":"Three human T cell clones (TCC) specific for purified protein derivative of Mycobacterium tuberculosis were incubated in the presence of polybrene and phytohemagglutinin with irradiated mononuclear cells from one individual exhibiting seropositivity for human immunodeficiency virus (HIV) and high levels of circulating p24 antigen. After three weeks, TCC showed HIV integration in their DNA, as shown by polymerase chain reaction analysis and Southern blot technique. All the three HIV-infected TCC maintained their ability to recognize the specific antigen, even if their proliferative ability was reduced. The ability of the HIV-infected TCC to produce IL-2, IL-4 and IFN-gamma in response to phorbol myristate acetate plus anti-CD3 monoclonal antibody was decreased, whereas their ability to produce TNF-alpha was unaffected or even enhanced. Two out of the three HIV-infected TCC showed the ability to provide helper function for polyclonal immunoglobulin production when cocultured with autologous B cells in the absence of any stimulant. These data suggest that in vitro infection of normal human TCC may provide a useful model for the study of immunological alterations induced by HIV.","PeriodicalId":76092,"journal":{"name":"La Ricerca in clinica e in laboratorio","volume":"21 1","pages":"85-90"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/BF02919116","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12878429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Studies on the epidemiology of child infections in the Bari area. I. Current state of immunity against Coxsackie B viruses. 巴里地区儿童感染流行病学研究。1 .目前对柯萨奇B型病毒的免疫状况。

La Ricerca in clinica e in laboratorio Pub Date : 1991-01-01 DOI: 10.1007/BF02919118

G Leogrande

引用次数: 1