American Journal of Gastroenterology最新文献

{"title":"Evaluating Artificial Intelligence-Driven Responses to Acute Liver Failure Queries: A Comparative Analysis Across Accuracy, Clarity, and Relevance.","authors":"Sheza Malik, Lewis J Frey, Jason Gutman, Asim Mushtaq, Fatima Warraich, Kamran Qureshi","doi":"10.14309/ajg.0000000000003255","DOIUrl":"10.14309/ajg.0000000000003255","url":null,"abstract":"<p><strong>Introduction: </strong>Recent advancements in artificial intelligence (AI), particularly through the deployment of large language models (LLMs), have profoundly impacted healthcare. This study assesses 5 LLMs-ChatGPT 3.5, ChatGPT 4, BARD, CLAUDE, and COPILOT-on their response accuracy, clarity, and relevance to queries concerning acute liver failure (ALF). We subsequently compare these results with ChatGPT4 enhanced with retrieval augmented generation (RAG) technology.</p><p><strong>Methods: </strong>Based on real-world clinical use and the American College of Gastroenterology guidelines, we formulated 16 ALF questions or clinical scenarios to explore LLMs' ability to handle different clinical questions. Using the \"New Chat\" functionality, each query was processed individually across the models to reduce any bias. Additionally, we employed the RAG functionality of GPT-4, which integrates external sources as references to ground the results. All responses were evaluated on a Likert scale from 1 to 5 for accuracy, clarity, and relevance by 4 independent investigators to ensure impartiality.</p><p><strong>Results: </strong>ChatGPT 4, augmented with RAG, demonstrated superior performance compared with others, consistently scoring the highest (4.70, 4.89, 4.78) across all 3 domains. ChatGPT 4 exhibited notable proficiency, with scores of 3.67 in accuracy, 4.04 in clarity, and 4.01 in relevance. In contrast, CLAUDE achieved 3.04 in clarity, 3.6 in relevance, and 3.65 in accuracy. Meanwhile, BARD and COPILOT exhibited lower performance levels; BARD recorded scores of 2.01 in accuracy and 3.03 in relevance, while COPILOT obtained 2.26 in accuracy and 3.12 in relevance.</p><p><strong>Discussion: </strong>The study highlights Chat GPT 4 +RAG's superior performance compared with other LLMs. By integrating RAG with LLMs, the system combines generative language skills with accurate, up-to-date information. This improves response clarity, relevance, and accuracy, making them more effective in healthcare. However, AI models must continually evolve and align with medical practices for successful healthcare integration.</p>","PeriodicalId":7608,"journal":{"name":"American Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-12-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142845613","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on Treatment Decision for Locally Resected T1 Colorectal Carcinoma Verification of the Japanese Guideline Criteria for Additional Surgery Based on Long-Term Clinical Outcomes.","authors":"Yinfang Wu, Qi Zhao","doi":"10.14309/ajg.0000000000003230","DOIUrl":"https://doi.org/10.14309/ajg.0000000000003230","url":null,"abstract":"","PeriodicalId":7608,"journal":{"name":"American Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142826832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comments on Limited Sustained Remission After Nucleos(t)ide Analog Withdrawal: Results From a Large, Global, Multiethnic Cohort of Patients With Chronic Hepatitis B (RETRACTB Study).","authors":"Yinfang Wu, Zhongwei Zhang","doi":"10.14309/ajg.0000000000003206","DOIUrl":"https://doi.org/10.14309/ajg.0000000000003206","url":null,"abstract":"","PeriodicalId":7608,"journal":{"name":"American Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142826732","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Antivirals in Preventing Perinatal Transmission of Hepatitis B: Start and Stop Times are Shifting.","authors":"Norah A Terrault, Hugo E Vargas","doi":"10.14309/ajg.0000000000003177","DOIUrl":"https://doi.org/10.14309/ajg.0000000000003177","url":null,"abstract":"","PeriodicalId":7608,"journal":{"name":"American Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142798676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metoclopramide May Not Decrease the Need for Second-Look Esophagogastroduodenoscopy in Patients With Overall Active Upper Gastrointestinal Bleeding.","authors":"Wenjing Sun, Kangqi Wu","doi":"10.14309/ajg.0000000000003189","DOIUrl":"https://doi.org/10.14309/ajg.0000000000003189","url":null,"abstract":"","PeriodicalId":7608,"journal":{"name":"American Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142798694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to Borup et al.","authors":"Anne-Marie Ellegaard, Martin L Kårhus, Matilde Winther-Jensen, Filip K Knop, Line L Kårhus","doi":"10.14309/ajg.0000000000003200","DOIUrl":"https://doi.org/10.14309/ajg.0000000000003200","url":null,"abstract":"","PeriodicalId":7608,"journal":{"name":"American Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142798938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Supplementary Considerations on the Timing of Direct Oral Anticoagulants Resumption.","authors":"Xin Zhou, Xiaofeng Zhang, Yaling Li, Jun Li","doi":"10.14309/ajg.0000000000003188","DOIUrl":"https://doi.org/10.14309/ajg.0000000000003188","url":null,"abstract":"","PeriodicalId":7608,"journal":{"name":"American Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142798945","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on \"Gallstone Disease Is Associated With an Increased Risk of Inflammatory Bowel Disease: Results From 3 Prospective Cohort Studies\".","authors":"Ziwei Gao, Jiachen Qi, Wei Ye","doi":"10.14309/ajg.0000000000003186","DOIUrl":"https://doi.org/10.14309/ajg.0000000000003186","url":null,"abstract":"","PeriodicalId":7608,"journal":{"name":"American Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142798693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Arsenic Exposure in Celiac Disease: The Hidden Cost of a Gluten-Free Diet.","authors":"Tracey M DaFonte, Maureen M Leonard","doi":"10.14309/ajg.0000000000003203","DOIUrl":"https://doi.org/10.14309/ajg.0000000000003203","url":null,"abstract":"","PeriodicalId":7608,"journal":{"name":"American Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-12-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142798679","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When Subtraction Wins, What Are the Considerations for Addition in Helicobacter pylori Eradication?","authors":"Qingzhou Kong, Yueyue Li","doi":"10.14309/ajg.0000000000003183","DOIUrl":"https://doi.org/10.14309/ajg.0000000000003183","url":null,"abstract":"","PeriodicalId":7608,"journal":{"name":"American Journal of Gastroenterology","volume":" ","pages":""},"PeriodicalIF":8.0,"publicationDate":"2024-12-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142765522","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}