{"title":"[Application of lactate threshold in the exercise program for patients with coronary heart disease].","authors":"M Takeda, K Tanaka, K Asano, Y Watanabe, T Hiyama","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study was conducted 1) to measure the exercise intensity corresponding to lactate threshold (LT) and 2) to clarify the method of prescribing LT level for patients with coronary heart disease (CHD) on the assumption that LT level indicates an optimal exercise intensity for those patients. Three males and 9 females with CHD, aged 57.6 +/- 7.7, participated in this study. Oxygen uptake (VO2), heart rate (HR), and ratings of perceived exertion (RPE) at LT and at maximal exercise were measured before (pre), 4 months (mid) and 8 months (post) after exercise conditioning. The intensity of most exercises was maintained at the level of LT. A significant increase was found in VO2LT from pre- to mid-test, and further increase was found from mid- to post-test after matching exercise intensity to the improvement in VO2LT. It is suggested that matching the progression of the absolute exercise intensity with the training-induced improvements of aerobic capacity i.e., maintaining the exercise intensity at LT for a sustained period of time, is a valid procedure for further improvement in aerobic capacity of CHD patients.</p>","PeriodicalId":76077,"journal":{"name":"Kokyu to junkan. Respiration & circulation","volume":"41 10","pages":"999-1003"},"PeriodicalIF":0.0,"publicationDate":"1993-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19223791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Transcatheter embolization of ascending aorto-pulmonary fistula combined with coronary arteriovenous fistula].","authors":"T Ohta, S Okumura, M Hujioka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We encountered a patient with a coronary arteriovenous fistula accompanied by an ascending aortopulmonary fistula, a rare malformation. The patient was a 42-year-old female complaining of exertional dyspnea and chest pain at rest. She noticed dyspnea while going up and down the stairs, and chest pain at rest at the age of about 40 years. While she was being treated for hypertension, a cardiac murmur was detected. She was admitted to our hospital for close examination. Coronary angiography (CAG) showed a coronary arteriovenous fistula that branches from the left anterior descending branch and forms an aneurysm, running to the trunk of the pulmonary artery. On March 28, 1989, ligation of the fistula was performed. Postoperative CAG demonstrated an ascending aorto-pulmonary fistula that flowed to an aneurysm adjacent to the pulmonary artery. On November 29, transcatheter embolization was performed. She was discharged 7 days after embolization without complications. She is now being treated on an outpatient basis, and the symptoms in her chest have disappeared. Transcatheter embolization used in this patient may also be applicable in the treatment for coronary arteriovenous fistulae.</p>","PeriodicalId":76077,"journal":{"name":"Kokyu to junkan. Respiration & circulation","volume":"41 10","pages":"1005-8"},"PeriodicalIF":0.0,"publicationDate":"1993-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19223780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K Takeyama, J Tamaoki, A Chiyotani, N Sakai, T Kanemura, K Konno
{"title":"[Stimulation of ciliary motility by beta 3-adrenoceptor agonist rabbit tracheal epithelium].","authors":"K Takeyama, J Tamaoki, A Chiyotani, N Sakai, T Kanemura, K Konno","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To determine whether atypical beta-adrenoceptor (beta 3-adrenoceptor) agonist, BRL 37344, stimulates airway ciliary motility and, if so, what its mechanism of action is, we studied rabbit tracheal epithelium in vitro. Epithelial cells cultured for 7 days were mounted in the Rose chamber and ciliary beat frequency (CBF) was measured by a photoelectric method. Addition of BRL 37344 rapidly increased CBF from 15.5 +/- 0.6 to 20.3 +/- 1.4 Hz (mean +/- SE, p < 0.01), which remained elevated for at least 20 min. This effect was concentration-dependent, the maximal increase from the baseline value and the EC50 being 27.2 +/- 0.4% (mean +/- SE, p < 0.01) and 1.75 x 10(-7) M, respectively. Other beta-adrenoceptor agonists likewise increased CBF, where the rank order of potency was salbutamol (1) > BRL 37344 (0.57) >> norepinephrine (1.3 x 10(-3)). Preincubation of cells with propranolol inhibited the increase in CBF produced by salbutamol, and BRL 37344 significantly raised intracellular cyclic AMP contents. These results suggest that beta 3-adrenoceptor probably exists in rabbit tracheal epithelium and that stimulation of this type of receptor increases ciliary motility through a cyclic AMP-dependent mechanism, an effect that might be of value in enhancing mucociliary transport function in the airway.</p>","PeriodicalId":76077,"journal":{"name":"Kokyu to junkan. Respiration & circulation","volume":"41 10","pages":"993-7"},"PeriodicalIF":0.0,"publicationDate":"1993-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18899610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Antihypertensive therapy based on 5th National Joint Committee Report].","authors":"H Suzuki","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76077,"journal":{"name":"Kokyu to junkan. Respiration & circulation","volume":"41 10","pages":"961-5"},"PeriodicalIF":0.0,"publicationDate":"1993-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18899609","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Okada, Y Tanaka, M Kasida, N Akatuka, Y Suzuki, K Yoshimoto, S Saima, Y Nakamura, T Tanaka
{"title":"[Two case reports of refractory heart failure treated by continuous ambulatory peritoneal dialysis].","authors":"M Okada, Y Tanaka, M Kasida, N Akatuka, Y Suzuki, K Yoshimoto, S Saima, Y Nakamura, T Tanaka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In this report, we present 2 cases of severe congestive heart failure and mild renal insufficiency in patients who underwent continuous ambulatory peritoneal dialysis (CAPD) after stabilization using the extracorporeal ultrafiltration method (ECUM). Long-term good control of congestive heart failure was achieved following the institution of CAPD. Case 1, a 58-year-old woman with rheumatic arthritis and diabetes mellitus had anteroseptal myocardial infarction at the age of 52. And case 2, a 68-year-old man, who underwent coronary artery bypass surgery at the age of 66 and had extensive anterior infarction after the operation. They were admitted to the hospital with dyspnea due to congestive heart failure. In both cases, systolic cardiac function was severely impaired and mild renal insufficiency was present at the time of hospitalization. After admission, symptomatic relief was not obtained by conventional therapies and symptoms of congestive heart failure worsened until the patients suffered from severe respiratory distress even at rest. ECUM was then instituted to remove excess fluid and clinical improvement was achieved. After the initiation of ECUM, responsiveness to diuretics was not restored, and the procedure was necessary every day or every other day for the prevention of symptoms due to fluid overload. About 20 days after the initiation of ECUM, CAPD was begun for the long-term control of congestive heart failure and renal failure, and for the purpose of hospital discharge. Good control of heart failure was achieved after the initiation of CAPD.(ABSTRACT TRUNCATED AT 250 WORDS)</p>","PeriodicalId":76077,"journal":{"name":"Kokyu to junkan. Respiration & circulation","volume":"41 10","pages":"1013-8"},"PeriodicalIF":0.0,"publicationDate":"1993-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19223782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Operative surgery of obstructive sleep apnea syndrome].","authors":"A Kataura","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76077,"journal":{"name":"Kokyu to junkan. Respiration & circulation","volume":"41 9","pages":"845-9"},"PeriodicalIF":0.0,"publicationDate":"1993-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19200528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}