T Ishida, A Kusui, M Tomita, T Fukami, M Hatani, Y Katada, K Kogame, T Tomomatsu, K Shirasaka
{"title":"[Two cases of Swyer-James syndrome].","authors":"T Ishida, A Kusui, M Tomita, T Fukami, M Hatani, Y Katada, K Kogame, T Tomomatsu, K Shirasaka","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Case 1: 55-year-old male was admitted to our hospital for further examination of increased transparency of X-ray in the left lower lung. He had history of pneumonia in his childhood. Left bronchography revealed mild cylindrical bronchi-ectasia in the proximal bronchi but poor filling by contrast in the peripheral bronchi. Case 2: 61-year-old male was referred to our hospital with palpitation and dyspnea. Chest X-ray film revealed hyperlucency of the left lower lung. The ventilation scan showed a marked decrease in ventilation to the left lung and air trapping was present in the left lung. The perfusion scan showed a matched decrease in blood supply to the left lung. In both cases, pulmonary arteriogram showed narrowed and withered-tree-like left pulmonary arteries. From these clinical findings, we diagnosed these two cases as Swyer-James syndrome. We are reporting two cases of Swyer-James syndrome and describing the clinical feature, differential diagnosis and etiology of the syndrome.</p>","PeriodicalId":76077,"journal":{"name":"Kokyu to junkan. Respiration & circulation","volume":"41 11","pages":"1095-9"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19243912","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Need for large sample size in clinical trial and statistical analysis of data from the trials].","authors":"H Miyahara","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76077,"journal":{"name":"Kokyu to junkan. Respiration & circulation","volume":"41 11","pages":"1025-32"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19244066","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Sugihara, Y Taniguchi, K Ohtsuki, I Umamoto, T Nakazawa, T Shima, T Nakamura, A Azuma, Y Kohno, M Nakagawa
{"title":"[Assessment of myocardial perfusion abnormalities in patients with apical hypertrophic cardiomyopathy using exercise 201Tl scintigraphy].","authors":"H Sugihara, Y Taniguchi, K Ohtsuki, I Umamoto, T Nakazawa, T Shima, T Nakamura, A Azuma, Y Kohno, M Nakagawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Regional myocardial perfusion abnormalities commonly occur during exercise in patients with hypertrophic cardiomyopathy (HCM). Exercise 201Tl myocardial scintigraphy has provided a noninvasive means of identifying myocardial perfusion abnormalities in patients with HCM. On the other hand, apical hypertrophic cardiomyopathy (APH) is reported as a subtype of HCM. Whether APH is essentially equal to HCM or not is controversial. To assess myocardial ischemia in patients with APH, we studied 28 patients with APH, with exercise 201Tl SPECT. Myocardial perfusion images were obtained immediately after submaximal exercise and again after a 3-hour delay. Regional perfusion defects during exercise were identified in 19 of the 28 patients (68%) with APH. Complete reversible defects were observed in 15 (79%) patients with APH. Although perfusion defects were present in all regions of the left ventricle in patients with HCM, they were present only in the apical region in patients with APH. Thus, reversible 201Tl perfusion abnormalities commonly occur during exercise in patients with APH as well as in patients with HCM.</p>","PeriodicalId":76077,"journal":{"name":"Kokyu to junkan. Respiration & circulation","volume":"41 11","pages":"1089-93"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19243911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Kubo, S Matsuoka, Y Ushiroguchi, K Tatara, Y Matsuka, Y Kuroda
{"title":"[Study of suitable analyzed signal duration and criteria for abnormal signal averaged electrocardiogram on frequency-domain analysis in patients with Duchenne's muscular dystrophy].","authors":"M Kubo, S Matsuoka, Y Ushiroguchi, K Tatara, Y Matsuka, Y Kuroda","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We investigated the optimal condition to detect abnormalities on the fast-Fourier transformation of the signal-averaged electrocardiogram (SA-ECG) by studying the effects of analyzed signal duration, attenuation of low frequency components by using filtering processing and the criteria for abnormal SA-ECG. Subjects were 23 patients with Duchenne's muscular dystrophy (DMD) and were divided into two groups by the presence of ventricular tachycardia (VT). Age-matched healthy volunteers were obtained as controls. Abnormal SA-ECG was identified from the data in the controls as over 97 percentile of H/L ratio. Frequency domain analysis from last 40 ms of QRS wave to 80 ms of ST segment was most capable to distinguish the DMD patients with VT from the patients without VT, compared to analysis from last 20 ms. Whereas, analysis from QRS onset failed to detect VT patients. Although filter processing reduce the power of low frequency and increase the H/L ratio, sensitivity for predicting VT was not enhanced significantly. In conclusion, the frequency-domain analysis during the terminal 40 ms of the QRS complex and 80 ms of ST segment was most optimal condition to distinguish the DMD patients with VT.</p>","PeriodicalId":76077,"journal":{"name":"Kokyu to junkan. Respiration & circulation","volume":"41 11","pages":"1073-8"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19244071","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Nishizawa, H Miyazaki, K Ogawa, S Takita, K Hashimoto, M Sugiyama, Y Okutsu
{"title":"[Comparison of standard-dose epinephrine and high-dose epinephrine in cardiopulmonary arrest outside the hospital].","authors":"H Nishizawa, H Miyazaki, K Ogawa, S Takita, K Hashimoto, M Sugiyama, Y Okutsu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We compared high-dose epinephrine (HDE) with standard-dose epinephrine (SDE) in improving the outcome of resuscitation after out-of-hospital cardiopulmonary arrest. The SDE group received epinephrine 1mg, and the HDE group received epinephrine 5mg respectively every 5 minutes until the return of spontaneous circulation. There were no significant differences between the SDE group and the HDE group in the rate of return of spontaneous circulation, rate of successful resuscitation and neurologic outcome. However, the rate of successful resuscitation tended to be higher in the SDE group. The ineffectiveness of HDE was considered to be due to the existence coronary artery diseases in the majority of patients, or increase in myocardial oxygen demand by the beta 1-adrenergic effects of epinephrine.</p>","PeriodicalId":76077,"journal":{"name":"Kokyu to junkan. Respiration & circulation","volume":"41 11","pages":"1083-7"},"PeriodicalIF":0.0,"publicationDate":"1993-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19244073","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
T Ikeda, K Sugi, H Fukazawa, Y Enjoji, M Kasao, K Yamashita, R Abe, K Ninomiya, S Yabuki, T Yamaguchi
{"title":"[An experimental study of catheter ablation using microwave energy via coaxial electrode catheter].","authors":"T Ikeda, K Sugi, H Fukazawa, Y Enjoji, M Kasao, K Yamashita, R Abe, K Ninomiya, S Yabuki, T Yamaguchi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The purpose of this study was to examine the efficacy, arrhythmogenicity, and the size of ablated lesions of catheter ablation with microwave energy. Microwave energy generated by a device with a frequency of 2450 MHz, was delivered via a bipolar electrode coaxial catheter with an electrode ball tip. Microwave ablation was applied (50 watts for 15-150 sec.) on the left ventricular endocardium in 6 dogs. No ventricular arrhythmia occurred during ablation in any of the dogs when microwave catheter ablation was applied for less than 45 sec. However, when the duration of microwave catheter ablation was longer than 45-60 sec, ventricular premature contractions were observed in all 6 dogs. When ablation time was set for a longer time, the dogs developed nonsustained ventricular tachycardias. Nevertheless, ventricular arrhythmias after ablation did not occur in all dogs. Ventricular programmed stimulation after ablation did not induce ventricular tachycardia in any of the dogs. When ablation time lasted more than 120 sec, the coagulation layer was extended to the epicardium in all 6 dogs. The results of this study suggest that microwave ablation is feasible for the treatment of tachyarrhythmias from a deep focus of the ventricular myocardium.</p>","PeriodicalId":76077,"journal":{"name":"Kokyu to junkan. Respiration & circulation","volume":"41 10","pages":"981-5"},"PeriodicalIF":0.0,"publicationDate":"1993-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19223789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R Sakai, D Inoue, K Ishibashi, M Inoue, I Omori, Y Yamahara, J Asayama, M Nakagawa
{"title":"[Frequency dependent prolongation of inter-atrial conduction time by mexiletine in human atrium].","authors":"R Sakai, D Inoue, K Ishibashi, M Inoue, I Omori, Y Yamahara, J Asayama, M Nakagawa","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>To investigate frequency dependent conduction slowing by mexiletine in the human atrium, we examined inter-atrial conduction time (IACT) at different stimulation frequencies (100/min to 220/min) in 13 patients with paroxysmal atrial fibrillation (Paf) and 7 patients without Paf. IACT was prolonged as the stimulation frequency was increased, and either before or after mexiletine administration IACT was longer in the Paf group (max 114 +/- 9 msec, p < 0.01, mean +/- SD) at any stimulation frequency than in the non-Paf group (max 100 +/- 8 msec). The change in IACT induced by mexiletine administration (% delta IACT) was larger in the Paf group (max 14.8 +/- 5.4%, p < 0.05) than in the non-Paf group (max 5.5 +/- 2.2%) at stimulation frequency over 140/min. Effective refractory period measured at the high right atrium was slightly decreased due to mexiletine in both the non-Paf and the Paf group. In conclusion, mexiletine showed frequency dependent suppression of conduction in the human atrial myocardium especially in patients with Paf.</p>","PeriodicalId":76077,"journal":{"name":"Kokyu to junkan. Respiration & circulation","volume":"41 10","pages":"987-91"},"PeriodicalIF":0.0,"publicationDate":"1993-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19223790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S Tasaka, A Kawai, A Ishizaka, K Yamaguchi, M Kanazawa, T Kawashiro, T Yokoyama
{"title":"[A case of congenital antithrombin III deficiency with pulmonary thromboembolism and cerebellar infarction].","authors":"S Tasaka, A Kawai, A Ishizaka, K Yamaguchi, M Kanazawa, T Kawashiro, T Yokoyama","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A 41-year old woman was admitted to a local hospital because of leg pain, chest pain and dyspnea after taking estrogen for two months for irregular menstruation. On admission to the hospital, her lung scintigram showed multiple segmental perfusion defects in the right lung. Pulmonary angiography showed several thrombi in the proximal pulmonary artery. A diagnosis of pulmonary thromboembolism was made. AT-III activity was found to be only 50% of normal value, indicating that the pulmonary thromboemboli were due to AT-III deficiency. The patient was then put on anticoagulants for two years. When she was 43-year-old, she was admitted to Keio University Hospital because of worsening of dyspnea. After admission her dyspnea had got better due to bed rest. Her brain CT, which was performed because of her gait disturbance, indicated past right cerebellar infarction. We gave her 2 mg of warfarin and maintained a thrombotest of about 30%. The investigation of her family revealed that her son also showed decrease AT-III activity, indicating a congenital abnormality. 26 families with this disease have been reported in Japan. Most had venous thromboemboli, but only a few cases had brain infarction as well. In addition, it is suggested that an estrogen therapy for irregular menstruation may have contributed, in this particular case, to the onset of thromboemboli.</p>","PeriodicalId":76077,"journal":{"name":"Kokyu to junkan. Respiration & circulation","volume":"41 10","pages":"1009-12"},"PeriodicalIF":0.0,"publicationDate":"1993-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19223781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Eosinophils: eosinophil's infiltrations into the lung tissue and increases in peripheral blood].","authors":"I Doi, M Munakata, Y Kawakami","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":76077,"journal":{"name":"Kokyu to junkan. Respiration & circulation","volume":"41 10","pages":"953-9"},"PeriodicalIF":0.0,"publicationDate":"1993-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19223786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}