[同轴电极导管微波能量消融的实验研究]。

T Ikeda, K Sugi, H Fukazawa, Y Enjoji, M Kasao, K Yamashita, R Abe, K Ninomiya, S Yabuki, T Yamaguchi
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引用次数: 0

摘要

本研究的目的是探讨微波消融术的疗效、心律失常性和消融病灶的大小。该装置产生的微波能量频率为2450mhz,通过带电极球头的双极电极同轴导管输送。采用微波消融术(50瓦,15 ~ 150秒)对6只狗左室心内膜进行消融术。当微波导管消融时间小于45秒时,6只犬均未出现室性心律失常。然而,当微波导管消融时间大于45-60秒时,6只犬均出现室性早搏。当消融术时间延长时,狗出现非持续性室性心动过速。然而,并非所有的狗在消融后都发生室性心律失常。消融后的心室程序性刺激没有引起任何狗的室性心动过速。当消融时间大于120秒时,6只狗的凝血层均延伸至心外膜。本研究结果提示,微波消融术从心室心肌深部病灶治疗快速心律失常是可行的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
[An experimental study of catheter ablation using microwave energy via coaxial electrode catheter].

The purpose of this study was to examine the efficacy, arrhythmogenicity, and the size of ablated lesions of catheter ablation with microwave energy. Microwave energy generated by a device with a frequency of 2450 MHz, was delivered via a bipolar electrode coaxial catheter with an electrode ball tip. Microwave ablation was applied (50 watts for 15-150 sec.) on the left ventricular endocardium in 6 dogs. No ventricular arrhythmia occurred during ablation in any of the dogs when microwave catheter ablation was applied for less than 45 sec. However, when the duration of microwave catheter ablation was longer than 45-60 sec, ventricular premature contractions were observed in all 6 dogs. When ablation time was set for a longer time, the dogs developed nonsustained ventricular tachycardias. Nevertheless, ventricular arrhythmias after ablation did not occur in all dogs. Ventricular programmed stimulation after ablation did not induce ventricular tachycardia in any of the dogs. When ablation time lasted more than 120 sec, the coagulation layer was extended to the epicardium in all 6 dogs. The results of this study suggest that microwave ablation is feasible for the treatment of tachyarrhythmias from a deep focus of the ventricular myocardium.

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