Journal of hygiene, epidemiology, microbiology, and immunology最新文献_第8页

WHO issues new estimates on global AIDS situation. Paediatric AIDS cases send estimates soaring. 世卫组织发布关于全球艾滋病形势的新估计。儿童艾滋病病例使估计数字飙升。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

引用次数: 0

Protective and other biological properties of Bacillus anthracis soluble antigens. 炭疽芽孢杆菌可溶性抗原的保护性及其它生物学特性。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

V A Abalakin, T D Cherkasova, L V Sergeeva, B L Cherkassky

{"title":"Protective and other biological properties of Bacillus anthracis soluble antigens.","authors":"V A Abalakin, T D Cherkasova, L V Sergeeva, B L Cherkassky","doi":"","DOIUrl":"","url":null,"abstract":"The soluble antigens were explored of the culture filtrate (CF) derived during static growth of B. anthracis vaccine strain 34F2 on a medium containing casein hydrolysate. Electrofocusing of CF preparations revealed that the protective activity was distributed over a wide range of pH 3-7. The most pronounced and stable protective activity was observed at pH 4.6-4.8. Following toxin factors were isolated and identified: protective antigen (87 kD), oedema factor (87 kD) and lethal factor (78-81 kD). The greatest protective activity was associated with antigens characterized by a molecular weight of 78-87 kD and toxic activity. Preparations of the oedema and lethal factors had the same protective activity as protective antigen (PA) preparations. Other CF soluble antigens protected about 30% of immunized guinea pigs. A protein was isolated with a molecular weight of 80 kD and isoelectric point at pH 5.3-5.7 which was not toxic and did not form toxic mixtures in association with other toxin factors; this protein featured a high immunogenic activity, however, it protected only 31% of immunized animals. Factors are analyzed which determine differences in the protective effects of live and chemical vaccines.","PeriodicalId":76007,"journal":{"name":"Journal of hygiene, epidemiology, microbiology, and immunology","volume":"35 1","pages":"83-95"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13068887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Carbon disulfide exposure attenuates adrenergic inotropic response in rats. 二硫化碳暴露可减弱大鼠的肾上腺素能性肌力反应。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

M Klapperstück, S Müller, P Hoffmann

引用次数: 0

Lepromatous leprosy in Saudi female from central region. 沙特中部地区女性的麻风病。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

S al-Majed

引用次数: 0

Circulating antibodies against thermophilic actinomycetes in farmers and mushroom workers. 农民和蘑菇工人循环中抗嗜热放线菌的抗体。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

Y E Shen, V P Kurup, J N Fink

引用次数: 0

Transaminases changes and worm burden in multiple infection of Ancylostoma caninum in mice. 犬钩虫多次感染小鼠转氨酶变化及虫负荷。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

V V Vardhani

引用次数: 0

On the toxinogenicity of Pseudomonas aeruginosa strains. 铜绿假单胞菌菌株的毒性研究。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

V Majtán, A Hostacká, A Kosiarová, L Majtánová, S Kohútová

引用次数: 0

Factors influencing the efficiency of chelation therapy. 影响螯合治疗效果的因素。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

K Kostial, B Kargacin, R Arezina, M Landeka, I Simonović

{"title":"Factors influencing the efficiency of chelation therapy.","authors":"K Kostial, B Kargacin, R Arezina, M Landeka, I Simonović","doi":"","DOIUrl":"","url":null,"abstract":"The purpose of the present study was to obtain new data on the effect of age, route, dose and time of metal and chelating agent administration on the efficiency of chelation therapy. The experiments were performed on 1-2 and 6-week-old rats which received radioisotopes of metals--203Pb, 115 mCd, 203Hg and 141Ce intraperitoneally or orally. Chelating agents calcium ethylenediaminetetraacetate (CaEDTA), calcium and zinc diethylenetriaminepentaacetate (CaDTPA, ZnDTPA), 2,3-dimercapto-propane-sulfonate-1 (DMPS), dimercaptosuccinic acid (DMSA) and sodium N-(4-methoxybenzyl)-D-glucamine dithiocarbamate monohydrate (MeOBDCG) were administered twice by intraperitoneal or oral administration as early (immediately and 24 hr after metals) or delayed treatment (24 and 48 or 48 and 72 hr after metals). The animals were killed six days after metal administration and the retention was determined in the whole body, carcass and gut. After intraperitoneal administration of metals and chelating agents chelation therapy had much lower efficacy in younger than older animals. After ingestion of metals oral chelation therapy was more effective in younger than older animals. In suckling rats the treatment effectively reduced metal retention and this was mostly due to decrease in gut retention. This treatment in sucklings was also very effective in condition of late administration. In older rats early oral DMPS treatment after 203Hg ingestion is contraindicated since it increases significantly mercury retention while DMSA and ZnDTPA treatments reduced mercury retention. Delayed oral treatment with ZnDTPA and DMSA caused increased cadmium retention in older rats and decreased retention in sucklings. Opposite to results with CaDTPA, MeOBDCG was effective in reducing cadmium retention also when given as delayed treatment.(ABSTRACT TRUNCATED AT 250 WORDS)","PeriodicalId":76007,"journal":{"name":"Journal of hygiene, epidemiology, microbiology, and immunology","volume":"35 4","pages":"337-50"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12966637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Electrolytic exchange in organism under the conditions of vibration. Experimental studies. 生物体在振动条件下的电解交换。实验研究。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

D Tzvetkov, F Razboinikova, D Dimitrov, I Petrov

{"title":"Electrolytic exchange in organism under the conditions of vibration. Experimental studies.","authors":"D Tzvetkov, F Razboinikova, D Dimitrov, I Petrov","doi":"","DOIUrl":"","url":null,"abstract":"The study deals with a wide spectrum of indices of the electrolytic metabolism--sodium, potassium, calcium, chlorides, magnesium, iron, copper, zinc, cobalt and manganese--in blood, organs and tissues under the conditions of experimental chronic exposure of whole-body vibration frequency of 50 and 150 Hz and velocity of 85 mm.s-1 during a three months experiment (3 h daily) Reference methods were used for the determination of the indices--atom absorption spectrophotometry (variants with flame and without flame), coulometric chlorine titrator, flame photometry, etc. The indices were examined three times (1, 2 and 3rd months). Statistic analysis of the data showed significant changes in the number and the values of the indices and their character (increase or decrease) in comparison with the control values. The indices modifications occur early (at the end of the first month) and they proceed till the end of the experiment (till the end of the 3rd month) during the exposure to both frequencies, but are strongly expressed in the case of high frequency vibrations. The disorders in electrolytic metabolism established in the experiment testify that people exposed to vibrations are likely to suffer analogical changes and develop other pathologies--diseases of cardiovascular system, of blood and haematopoietic organs, etc. as well as an increase of specific disorders in connection with vibration exposure.","PeriodicalId":76007,"journal":{"name":"Journal of hygiene, epidemiology, microbiology, and immunology","volume":"35 3","pages":"259-70"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13119914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Environmental medicine. 环境医学。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01 DOI: 10.1007/springerreference_82357

K. Horn

引用次数: 0