Journal of hygiene, epidemiology, microbiology, and immunology最新文献_第10页

The role played the lipid fractions of Mycobacterium bovis BCG in the development of antituberculosis immunity in an animal experiment. 牛分枝杆菌BCG脂质组分在动物抗结核免疫发展中的作用。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

Z Sír, J Průchová, M Mára, H Mohelská, V Nedvĕdová, V Hyncica

{"title":"The role played the lipid fractions of Mycobacterium bovis BCG in the development of antituberculosis immunity in an animal experiment.","authors":"Z Sír, J Průchová, M Mára, H Mohelská, V Nedvĕdová, V Hyncica","doi":"","DOIUrl":"","url":null,"abstract":"The authors investigated the antituberculosis and antitumour immunogenicity as well as tuberculin allergenicity of the lipid fractions from Mycobacterium bovis BCG strains of Danish, French, Japanese origin and of Czechoslovak 725. The fractions explored included phospholipids, Cord factor, ethanol-extractable lipids, waxes A, B, C + D and fats. The fractions were divided into three groups according to their effectiveness. 1. The Cord factor and phospholipids from all the studied strains were effective in the antituberculosis and antitumour models with the only exception of strain 725 phospholipids. Phospholipids from all strains were capable of inducing tuberculin allergy. 2. In the second group (waxes A, C + D and lipids extractable by ethanol) a variance was observed in the antigenic properties of identical fractions from different strains suggesting differing metabolism in the strains producing these fractions. A mixture of waxes C + D from the French and Danish strains showed a degree of suppression in its antituberculosis effectiveness. 3. Waxes B and fats were entirely ineffective in the antitumour model and, with the exception of waxes B from strain 725 and fats from the Japanese strain, in the antituberculosis model. The antituberculosis and antitumour effectiveness directly depended on the content of a mycolic acid complex in fractions. Tuberculin allergenicity was associated with the intensity of phospholipid production by mycobacteria.","PeriodicalId":76007,"journal":{"name":"Journal of hygiene, epidemiology, microbiology, and immunology","volume":"35 1","pages":"73-82"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12879192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Filariasis in Gongola State Nigeria. I: Clinical and parasitological studies in Mutum-Biyu district. 尼日利亚贡戈拉州的丝虫病。1:穆图姆-比尤地区的临床和寄生虫学研究。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

O B Akogun

引用次数: 0

Family studies in common variable immunodeficiency. 常见可变免疫缺陷的家族研究。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

I Vorechovský, J Litzman, J Lokaj, R Sobotková

{"title":"Family studies in common variable immunodeficiency.","authors":"I Vorechovský, J Litzman, J Lokaj, R Sobotková","doi":"","DOIUrl":"","url":null,"abstract":"The occurrence of cancer, immunodeficiency, and diseases with possible autoimmune aetiology were studied in 355 blood relatives of 12 patients with common variable immunodeficiency (CVID). The family members were identified through the patients and interviewed after completing a questionnaire, their diseases were medically confirmed by local general practitioners. In two families consanguineous marriages were identified with the coefficients of inbreeding of 0.03125 and 0.01563, respectively: one patient, a dizygotic twin of an unaffected sister, was a granddaughter of first cousins, the second patient was the third daughter of second cousins. These cases of CVID strongly support the autosomal recessivity of the underlying genes. One male patient with CVID was shown to be related to a patient with X-linked hypogammaglobulinaemia, both sharing a common carrier. The different clinical courses of their diseases suggest two genetically determined immunodeficiencies and genetic heterogeneity. No family had an unusual clustering of cancer. The occurrence of tumours in the blood relatives of CVID patients was not significantly higher than in the relatives of spouse controls. Immunological examination of 30 first degree relatives of the CVID patients revealed three children (2 males and 1 female) with selective IgA deficiency, in one boy combined with elevated serum IgE level. Four relatives with rheumatoid heart disease, 12 cases of gastric or duodenal ulcer, and 14 relatives with thyroid disease represented the most often encountered diagnoses with a possible autoimmune component in their aetiology.","PeriodicalId":76007,"journal":{"name":"Journal of hygiene, epidemiology, microbiology, and immunology","volume":"35 1","pages":"17-26"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13041216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Bacterial isolates and drug susceptibility tests at Kaffa Regional Public Health Laboratory, south west Ethiopia. 埃塞俄比亚西南部Kaffa区域公共卫生实验室的细菌分离株和药敏试验。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

Z W/Tenssay

引用次数: 0

Haemagglutination-inhibiting antibodies against influenza A and B in human sera collected from five ecological zones in Nigeria. 从尼日利亚五个生态区采集的人血清中发现抗甲型和乙型流感的血凝素抑制抗体。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

D O Olaleye, S S Baba, S A Omilabu, A H Fagbami

{"title":"Haemagglutination-inhibiting antibodies against influenza A and B in human sera collected from five ecological zones in Nigeria.","authors":"D O Olaleye, S S Baba, S A Omilabu, A H Fagbami","doi":"","DOIUrl":"","url":null,"abstract":"The prevalence of antibodies to the haemagglutinins of two influenza A subtype, H1N1 and H3N2 and influenza B in sera collected from 1986 to 1988 from persons of different ages and from 10 locations in 5 ecological zones of Nigeria was determined. The levels of influenza antibodies in the sera varies with age and ecological zones of the country. A total of 1,022 sera were tested, of which 732 (71.6%) were positive for influenza antibodies. The prevalence of antibodies at titre 1:10 varied between 31.1% in the derived savannah and 94.4% in the swamp forest. The prevalence in the other zones were: rain forest 63.9%, guinea savannah 86.0% and 78.0% in sudan savannah. Reactors with the two influenza A subtypes antigens were more than reactors with influenza B antigens in the country. Antibody levels to influenza A subtypes varied between and within zones. Although there was no significant difference a (P greater than 0.05) in the overall prevalence of antibodies to the two subtypes, more sera had haemagglutination-inhibiting antibody to H1N1 subtype than H3N2 subtype in all the zones except in the rain forest. Prevalence of antibodies to influenza viruses increased with age in all the zones. Overcrowding in big cities and dry, dusty harmattan weather of the northern parts of the country are considered as possible risk factors in the epidemiology of influenza in Nigeria.","PeriodicalId":76007,"journal":{"name":"Journal of hygiene, epidemiology, microbiology, and immunology","volume":"35 4","pages":"395-406"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12966642","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Antibodies to lymphocytic choriomeningitis virus in wild rodent sera in Egypt. 埃及野生啮齿动物血清淋巴细胞性脉络丛脑膜炎病毒抗体。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

R M el Karamany, I Z Imam

引用次数: 0

Microflora of nuclear research reactor pool water. 核研究堆池水中微生物群。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

A Saadawi, A Ayad, V N Maltsev

引用次数: 0

Hantaviruses in small wild living mammals in Czechoslovakia. Results of a 1983-1989 study. 捷克斯洛伐克小型野生哺乳动物中的汉坦病毒。1983-1989年的研究结果。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

L Danes, M Pejcoch, Z Hubálek, J Halouzka, Z Juricová, J Zima, E A Tkachenko, T K Dzagurová, A P Ivanov, E Svandová

引用次数: 0

The NATO/CCMS Pilot Study on Indoor Air Quality. 北约/CCMS室内空气质素试验研究

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

M Maroni

引用次数: 0

On the microbiological diagnostics of Campylobacter jejuni. 空肠弯曲杆菌的微生物学诊断。

Journal of hygiene, epidemiology, microbiology, and immunology Pub Date : 1991-01-01

E Aldová, H Lhotová

{"title":"On the microbiological diagnostics of Campylobacter jejuni.","authors":"E Aldová, H Lhotová","doi":"","DOIUrl":"","url":null,"abstract":"Investigation of campylobacteriosis cases in 1983-1989 resulted in the isolation of a total of 245 antigenically identified and 23 unidentified strains from humans, animals and foods. A commonly accepted method developed in 1985 using our own experience was used for strain isolation and culturing. A variety of nutrient media in combination with different supplementary substances (antibiotics, growth factors) and additives, such as horse serum, were verified as well as filtration and Fortner's procedures. The best results were obtained when material was stored in thioglycolate transport medium accompanied by cold enrichment (24 h at 4 degrees C) and repeated inoculation into appropriate solid nutrient medium. Owing to the simple culturing of C. jejuni, the number of not elucidated diarrheas was reduced and the incidence of campylobacteriosis (approximately 12 %) is higher than that of salmonellosis and shigellosis. A total of 245 C. jejuni strains was classified using Kahlich's antigenic scheme. The incidence of serovars 1 and 2 was greater than 10 %. Five serovars (13, 17, 25, 26 and 27) were represented by only one strain. The study of campylobacteriosis also revealed the long-term excretion of C. jejuni by convalescents (71 days at most) as well as the occurrence of family outbreaks. Procedures were developed to ensure short-term and long-term (freeze-drying) preservation of isolated strains. The number of cases reported by microbiological laboratories in the framework of the Hygienic Service throughout Czechoslovakia suggest an increase in positive findings with C. jejuni as the etiological agent.","PeriodicalId":76007,"journal":{"name":"Journal of hygiene, epidemiology, microbiology, and immunology","volume":"35 2","pages":"199-207"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"13100220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0