P. Roozmon , S.A. Gracovetsky , G.J. Gouw , N. Newman
{"title":"Examining motion in the cervical spine II: characterization of coupled joint motion using an opto-electronic device to track skin markers","authors":"P. Roozmon , S.A. Gracovetsky , G.J. Gouw , N. Newman","doi":"10.1016/0141-5425(93)90087-F","DOIUrl":"10.1016/0141-5425(93)90087-F","url":null,"abstract":"<div><p>Analysis of coupled motion in the cervical spine may be useful in helping to identify injuries. In order to investigate this possibility, the nature of coupled motion in the spine and previous investigations on this subject are reviewed here. An enhanced set of displays are developed for an existing opto-electronic device employed for the non-invasive measurement of movement in the upper spine. This instrument consists of a high resolution motion analysis system which tracks small infrared emitting diodes (IREDs). Kinematic data for the motion of the markers is processed and absolute coordinates for the location of each IRED at any time are tabulated; coupled motion with respect to a fixed calibration frame, as well as for vertebrae relative to each other, is deduced from these. Overall analysis provided by the original device includes assessment of cervical lordosis, thoracic kyphosis, and inter-segmental mobility. Characterization of coupled motion, in particular, involves a series of plots showing principal <em>versus</em> secondary motion. Principal movements include flexion-extension, lateral bending, and axial rotation, corresponding to motion in the sagittal, transverse, and horizontal planes, respectively. Mobility is represented in terms of the direction angles made by virtual vectors orthogonal to the planes made by markers on the head, neck, and shoulders. Development of the enhanced displays and the required refinements are described. Precision of the deduced angles is found to be approximately 1°. This representation of coupled motion is expected to be valuable in improving the accuracy of attempts to identify normal <em>versus</em> pathological motion in the cervical spine.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 1","pages":"Pages 13-22"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90087-F","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19405223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M. Viceconti , F. Baruffaldi , W. Gaiba , A. Toni , A. Sudanese , A. Giunti
{"title":"Digital dynamic range expansion applied to X-ray densitometric analysis of total hip replacement","authors":"M. Viceconti , F. Baruffaldi , W. Gaiba , A. Toni , A. Sudanese , A. Giunti","doi":"10.1016/0141-5425(93)90094-F","DOIUrl":"10.1016/0141-5425(93)90094-F","url":null,"abstract":"<div><p>Due to the presence of the stiff prosthetic stem fitted in the medullary canal during total his replacement, the surrounding cortex of the femur changes its density over time. This bone remodelling takes place with every type of total hip prosthesis; however, its intensity may vary between prostheses and patients. In the worst cases this process can lead to the late failure of the implant. To monitor such bone density evolution, we are developing a tailored Computer-aided Densitometric Image Analysis system (the major part of this our system uses an 8-bit commercial hardware with 256 levels of grey). The equivalent dynamic range of an X-ray picture is about 10 bits. In this paper we present a method to overcome these hardware limitations by improving the software. Using a double-exposure acquisition it is possible to build a 9-bit image that is good enough for most applications involving bone density measurement.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 1","pages":"Pages 57-59"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90094-F","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19403058","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"An alternative to screws for plating osteoporotic bone","authors":"T.StJ. King, D. Cebon","doi":"10.1016/0141-5425(93)90098-J","DOIUrl":"10.1016/0141-5425(93)90098-J","url":null,"abstract":"<div><p>There are several problems with existing techniques used to plate broken bones. One of the most serious is that of screws pulling out during insertion or healing in patients suffering from osteoporosis. This paper investigates the mechanism of this pulling out, and proposes an alternative device to attach plates to weak bones.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 1","pages":"Pages 79-82"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90098-J","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19404976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
G.F. Harris , N. Yoganandan , D. Schmaltz , J. Reinartz , F. Pintar , A. Sances Jr
{"title":"A biomechanical impact test system for head and facial injury assessment and model development","authors":"G.F. Harris , N. Yoganandan , D. Schmaltz , J. Reinartz , F. Pintar , A. Sances Jr","doi":"10.1016/0141-5425(93)90096-H","DOIUrl":"10.1016/0141-5425(93)90096-H","url":null,"abstract":"<div><p>A biomechanical test system has been developed and validated to conduct controlled uniaxial impact experiments of head and facial trauma. The design reduces off-axis accelerations which are not in the direction of impact and allows accurate positioning of test specimens. Impact forces, displacement histories, impulses at impact and spectral responses are compared to free-fall test results at contact velocities representative of facial injuries (2.5, 3.1 and 3.8 m s<sup>−1</sup>). Models based on the experimental results are developed to reveal stiffness and inertial properties of impact for use in the design of biomechanically protective steering wheels, air bags and other potential impact structures. The results indicate that the system provides a flexible yet controllable method for positioning and testing impact structures reliably.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 1","pages":"Pages 67-73"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90096-H","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19404974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Improving limb flexion in FES gait using the flexion withdrawal response for the spinal cord injured person","authors":"M.H. Granat , B.W. Heller , D.J. Nicol , R.H. Baxendale , B.J. Andrews","doi":"10.1016/0141-5425(93)90093-E","DOIUrl":"10.1016/0141-5425(93)90093-E","url":null,"abstract":"<div><p>In the restoration of gait for paraplegics using functional electrical stimulation, the method most commonly used to produce hip flexion for the swing phase of gait has been the elicitation of the flexion withdrawal response. Several problems have been noted with the response: there is a decrease in the magnitude of the hip flexion to repeated stimuli (habituation); long latency; and inhibition of the response when stimulated bilaterally. These have been characterized and methods for overcoming the problems tested. Results show that increasing stimulation frequency reduces latency. Habituation can be reduced in some subjects by multiplexing two sites of stimulation. Habituation can further be reduced by applying single high-intensity pulses and this has been used in a one-step-ahead controller for regulating hip flexion angle. Inhibition due to bilateral stimulation had been significantly reduced by altering the timing of the stimulation to the two legs.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 1","pages":"Pages 51-56"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90093-E","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19403057","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A.W.A. Crossley , C.J. Hull , M.A. Stafford , D.A. Smith
{"title":"Repetitive elastance measurement as a means of recording pharmocological responses in vascular smooth muscles","authors":"A.W.A. Crossley , C.J. Hull , M.A. Stafford , D.A. Smith","doi":"10.1016/0141-5425(93)90090-L","DOIUrl":"10.1016/0141-5425(93)90090-L","url":null,"abstract":"<div><p>We describe a method of recording pharmacological responses in isolated arterial segments, based on the direct measurement of vascular wall elastance. The segment outflow is intermittently occluded, and the elastance determined from the subsequent pressure—flow relationship. Since the measurement cycle can be repeated 12 times per minute, rapid pharmacological responses can be studied. The method is capable of demonstrating a sigmoid dose—response relationship to noradrenaline added to the perfusate.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 1","pages":"Pages 34-38"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90090-L","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19403053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The forces acting on the human calcaneus","authors":"A.L. Yettram, N.N. Camilleri","doi":"10.1016/0141-5425(93)90092-D","DOIUrl":"10.1016/0141-5425(93)90092-D","url":null,"abstract":"<div><p>The forces acting on the human calcaneus are analysed for a static standing posture. An optimization procedure is invoked to solve the statically indeterminate set of forces which could arise from muscles, ligaments and reactions between the calcaneus and other bones and also the ground. Two alternative objective functions are investigated; that which returns no active muscle force is considered the more realistic, since electromyographic studies show that in static standing only minor muscle activity occurs to counteract body sway. This set of forces is then applied to the bone for finite element stress analysis to produce stress trajectories, which are then validated against both the trabecular configuration of the cancellous bone of the calcaneus and also the distribution of the orientations of the hydroxyapatite crystal major and minor axes.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 1","pages":"Pages 46-50"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90092-D","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19403055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D.A. Noe, S.J. Voto, M.S. Hoffmann, M.J. Askew, I.A. Gradisar
{"title":"Role of the calcaneal heel pad and polymeric shock absorbers in attenuation of heel strike impact","authors":"D.A. Noe, S.J. Voto, M.S. Hoffmann, M.J. Askew, I.A. Gradisar","doi":"10.1016/0141-5425(93)90088-G","DOIUrl":"10.1016/0141-5425(93)90088-G","url":null,"abstract":"<div><p>The capacity of the calcaneal heel pad, with and without augmentation by a polymeric shock absorbing material (Sorbothane<sup>®</sup> 0050), to attenuate heel strike impulses has been studied using five fresh human cadaveric lower leg specimens. The specimens, instrumented with an accelerometer, were suspended and impacted with a hammer; a steel rod was similarly suspended and impacted. The calcaneal heel pad attenuated the peak accelerations by 80%. Attenuations of up to 93% were achieved by the shock absorbing material when tested against the steel rod; however, when tested in series with the calcaneal heel pad, the reduction in peak acceleration due to the shock absorbing material dropped to 18%. Any evaluation of the effectiveness of shock absorbing shoe materials must take into account their mechanical interaction with the body.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 1","pages":"Pages 23-26"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90088-G","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19405224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Image analysis in the evaluation of biomaterials","authors":"J.A. Hunt, D.G. Vince, D.F. Williams","doi":"10.1016/0141-5425(93)90091-C","DOIUrl":"10.1016/0141-5425(93)90091-C","url":null,"abstract":"<div><p>An examination regime, based on a computer-aided image analysis system, has been developed for the quantitative evaluation of the local tissue response to biomaterials. This procedure involves the immunoenzymic staining of tissue sections using monoclonal antibodies specific for certain inflammatory cell types. An avidin-biotin-horseradish peroxidase staining method is used to identify antibody binding sites and the sections are assayed using a computer-aided image analysis system. This regime facilitates the rapid and accurate measurement of 30 cell related parameters in sections stained for macrophages, polymorphonuclear leucocytes, and other cells.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"15 1","pages":"Pages 39-45"},"PeriodicalIF":0.0,"publicationDate":"1993-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(93)90091-C","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19403054","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Forces required for dilatation of human cervix in first trimester of pregnancy","authors":"A. Molin, J. Brundin","doi":"10.1016/0141-5425(92)90108-W","DOIUrl":"10.1016/0141-5425(92)90108-W","url":null,"abstract":"<div><p>Cervical resistance to dilatation was measured in 76 patients undergoing first trimester legal abortion; a specially designed force-sensing instrument was used. No correlation between cervical resistance and patient age or gestational age was found. Increasing parity and earlier legal abortions were significantly correlated with a lowering of the cervical resistance. In patients dilated to 11 mm a lowering of resistance was noted suggesting a tear in cervical tissue.</p></div>","PeriodicalId":75992,"journal":{"name":"Journal of biomedical engineering","volume":"14 6","pages":"Pages 527-529"},"PeriodicalIF":0.0,"publicationDate":"1992-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0141-5425(92)90108-W","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12605001","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}