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Tri-calcium phosphate as a bone substitute. 磷酸三钙作为骨替代物。
Journal of bioengineering Pub Date : 1977-01-01
B V Rejda, J G Peelen, K de Groot
{"title":"Tri-calcium phosphate as a bone substitute.","authors":"B V Rejda,&nbsp;J G Peelen,&nbsp;K de Groot","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Strong porous tri-calcium phosphate ceramic has been fabricated, and investigated as a bone implant material. No foreign body reaction was observed, while osteoclastic activity was shown to be involved in biodegradation. Bone mineral was deposited directly onto the surface of the ceramic implant.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"1 2","pages":"93-7"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11564879","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tissue, cellular and subcellular events at a bone-ceramic hydroxylapatite interface. 骨-陶瓷羟基磷灰石界面的组织、细胞和亚细胞事件。
Journal of bioengineering Pub Date : 1977-01-01
M Jarcho, J F Kay, K I Gumaer, R H Doremus, H P Drobeck
{"title":"Tissue, cellular and subcellular events at a bone-ceramic hydroxylapatite interface.","authors":"M Jarcho,&nbsp;J F Kay,&nbsp;K I Gumaer,&nbsp;R H Doremus,&nbsp;H P Drobeck","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A new polycrystalline form of hydroxylapatite, durapatite, has been examined as a cortical bone implant in dogs. Utilizing histological and electron optical techniques, it has been found that durapatite does not elicit a foreign body response and that all new bone surrounding the material is normally calcified. Bone was found to strongly adhere to durapatite and preliminary evidence suggests this bonding may be due to direct chemical attachment of bone to the material.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"1 2","pages":"79-92"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11566055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Silicon containing particles in ultra high molecular weight polythene. 含硅颗粒的超高分子量聚乙烯。
Journal of bioengineering Pub Date : 1977-01-01
H S Dobbs, J T Scales, K W Wright
{"title":"Silicon containing particles in ultra high molecular weight polythene.","authors":"H S Dobbs,&nbsp;J T Scales,&nbsp;K W Wright","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"1 2","pages":"113-4"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11818128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fabrication of pH-sensitive implantable electrode by thick film hybrid technology. 厚膜杂交技术制备ph敏感可植入电极。
Journal of bioengineering Pub Date : 1977-01-01
M A Afromowitz, S S Yee
{"title":"Fabrication of pH-sensitive implantable electrode by thick film hybrid technology.","authors":"M A Afromowitz,&nbsp;S S Yee","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>We report preliminary results of our experiments directed at fabricating pH-sensitive electrodes suitable for in vivo use by means of thick film screening techniques. Our results show that glass membranes of suitable thickness and possessing nearly theoretical sensitivity to pH can be fabricated by this process. A hybrid electrode structure permits the incorporation of a source follower FET amplifier directly adjacent to the pH membrane, significantly reducing response time and noise pick-up. Extension of the basic electrode structure to accommodate membranes sensitive to other ions is discussed.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"1 2","pages":"55-60"},"PeriodicalIF":0.0,"publicationDate":"1977-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11251398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Endothelium: newly discovered functions and methods of study. 内皮:新发现的功能和研究方法。
Journal of bioengineering Pub Date : 1976-11-01
R G Mason, H Y Chuang, S F Mohammad, D E Sharp
{"title":"Endothelium: newly discovered functions and methods of study.","authors":"R G Mason,&nbsp;H Y Chuang,&nbsp;S F Mohammad,&nbsp;D E Sharp","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"1 1","pages":"3-10"},"PeriodicalIF":0.0,"publicationDate":"1976-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11988761","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The adhesion of thin carbon films to metallic substrates. 碳薄膜与金属衬底的粘合。
Journal of bioengineering Pub Date : 1976-11-01
H S Shim, N K Agarwal, A D Haubold
{"title":"The adhesion of thin carbon films to metallic substrates.","authors":"H S Shim,&nbsp;N K Agarwal,&nbsp;A D Haubold","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>As part of the development of carbon-coated prosthetic devices, the adhesion of thin carbon films to metallic substrates has been studied. The bond strength of carbon films about 5000 A thick on Ti-6A1-4V and stainless steel was measured in a pull test and found to be greater than 4700 psi. Auger electron spectroscopy showed a reactive film/substrate interface. The ultimate bond strength was found to be dependent on the substrate and the deposition parameters.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"1 1","pages":"45-50"},"PeriodicalIF":0.0,"publicationDate":"1976-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12231140","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A microelectronic pH sensor. 微电子pH传感器。
Journal of bioengineering Pub Date : 1976-11-01
S D Moss, J B Smith, P A Comte, C C Johnson, L Astle
{"title":"A microelectronic pH sensor.","authors":"S D Moss,&nbsp;J B Smith,&nbsp;P A Comte,&nbsp;C C Johnson,&nbsp;L Astle","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This paper presents preliminary data on a new integrated circuit microelectronic pH sensor. The device is extremely miniaturized by the use of integrated circuit technology, and uses the intrinsic hydrogen ion selective properties of the gate insulator material. In order to make the device compatible with aqueous solution monitoring, the silicon dioxide-silicon nitride gate insulator structure is used. The integrated circuit chip was designed, processed, and packaged by a variety of techniques which protect all metal parts from the aqueous solution. Test data are reported on leakage current, sensitivity, reproducibility, linearity, stability, response time, and life. The results indicate that this type of pH sensor may have many significant advantages for biomedical research and application.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"1 1","pages":"11-20"},"PeriodicalIF":0.0,"publicationDate":"1976-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11251472","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biodegradable semipermeable microcapsules containing enzymes, hormones, vaccines, and other biologicals. 含有酶、激素、疫苗和其他生物制剂的可生物降解半透微胶囊。
Journal of bioengineering Pub Date : 1976-11-01
T M Chang
{"title":"Biodegradable semipermeable microcapsules containing enzymes, hormones, vaccines, and other biologicals.","authors":"T M Chang","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Semipermeable microcapsules were prepared using biodegradable material as the enclosing membranes. For instance, polylactic acid was used as membrane material to microencapsulate biologically active materials. Asparaginase microencapsulated within polylactic acids functions effectively in converting external asparagine into aspartic acid and ammonium. By variations in permeability characteristics, insulin microencapsulated within polylactic acid can be released at pre-adjusted rates. Thus, release rates of 50% in 5 hours, 50% in 20 hours, and 2.5% in 24 hours have been demonstrated. Drugs and vaccines have also been similarily microencapsulated. The advantage of the biodegradable microcapsules is the ability of the body to convert the injected polymer material to normal body metabolites (e.g., CO2 and H2O in the case of polylactic acid) after completion of its function.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"1 1","pages":"25-32"},"PeriodicalIF":0.0,"publicationDate":"1976-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12231138","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pure and filler free silicone rubber biomaterial; a new concept in preparing silicone rubber. 纯无填料硅橡胶生物材料;硅橡胶制备的新概念。
Journal of bioengineering Pub Date : 1976-11-01
A S Chawla
{"title":"Pure and filler free silicone rubber biomaterial; a new concept in preparing silicone rubber.","authors":"A S Chawla","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"1 1","pages":"51-3"},"PeriodicalIF":0.0,"publicationDate":"1976-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11425631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Platelet retention by albuminated glass and polystyrene beads. 用白化玻璃和聚苯乙烯珠保留血小板。
Journal of bioengineering Pub Date : 1976-11-01
D L Coleman, A I Atwood, J D Andrade
{"title":"Platelet retention by albuminated glass and polystyrene beads.","authors":"D L Coleman,&nbsp;A I Atwood,&nbsp;J D Andrade","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Ex vivo platelet retention by albuminated glass and polystyrene beads has been evaluated as a function of flow rate, bead surface area, blood exposure time and albumin treatment. The stability of the albumin coatings as well as scanning electron microscopy of the various surfaces before and after blood exposure has also been included. Results indicate that platelet retention is sensitive to changes in the above parameters and that albumin pretreatment of different substrates can decrease platelet retention. This decrease is substrate dependent in that platelet retention is different for the albuminated glass and polystyrene substrates. Chemical analysis of the substrate materials by X-ray photoelectron spectroscopy (XPS) as well as bulk chemical analysis is also reported.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"1 1","pages":"33-44"},"PeriodicalIF":0.0,"publicationDate":"1976-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12231139","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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