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Stress-induced structure and activity changes in biologically active proteins. 应激诱导生物活性蛋白的结构和活性变化。
Journal of bioengineering Pub Date : 1978-06-01
M V Tirrell
{"title":"Stress-induced structure and activity changes in biologically active proteins.","authors":"M V Tirrell","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"183-93"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11571381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The wear behavior of vacuum-vapor-deposited carbon films. 真空气相沉积碳膜的磨损性能。
Journal of bioengineering Pub Date : 1978-06-01
H S Shim, A D Haubold
{"title":"The wear behavior of vacuum-vapor-deposited carbon films.","authors":"H S Shim, A D Haubold","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"341-3"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11911978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Instrumentation for monitoring oxygen consumption using a replenishment technique. 用补充技术监测耗氧量的仪器。
Journal of bioengineering Pub Date : 1978-06-01
D B Raemer, C C Johnson
{"title":"Instrumentation for monitoring oxygen consumption using a replenishment technique.","authors":"D B Raemer,&nbsp;C C Johnson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An instrument to measure patient oxygen consumption simply and accurately has been built using a replenishment technique. Oxygen is added to the patient's exhaled gas until its oxygen concentration is the same as the oxygen concentration of the inhaled gas. The rate at which oxygen is added is a measure of the patient's oxygen consumption. Bench tests show that oxygen consumption is measured with an accuracy of +/- 2.3 percent and human tests show an accuracy of +/- 5.9 percent. The instrument interfaces easily with a mechanical ventilator and is readily accepted by the clinician.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"219-27"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11912153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Solute transport through crosslinked poly (2-hydroxyethyl methacrylate) membrane. 溶质通过交联聚(2-羟乙基甲基丙烯酸酯)膜的运输。
Journal of bioengineering Pub Date : 1978-06-01
K H Lee, J G Jee, M S Jhon, T Ree
{"title":"Solute transport through crosslinked poly (2-hydroxyethyl methacrylate) membrane.","authors":"K H Lee,&nbsp;J G Jee,&nbsp;M S Jhon,&nbsp;T Ree","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"269-78"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11912158","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The thrombogenicity of radiation grafted polymers as measured by the vena cava ring test. 通过腔静脉环试验测定放射接枝聚合物的血栓形成性。
Journal of bioengineering Pub Date : 1978-06-01
B D Ratner, A S Hoffman, J D Whiffen
{"title":"The thrombogenicity of radiation grafted polymers as measured by the vena cava ring test.","authors":"B D Ratner,&nbsp;A S Hoffman,&nbsp;J D Whiffen","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Radiation grafted hydrogels on silicone rubber with water contents ranging from 10--90% have been evaluated by the vena cava ring test. All hydrogel grafted materials were found to accumulate less thrombus than ungrafted silicone rubber, and graft level was found to have little effect on thrombus accumulation. Acrylamide grafts demonstrated superior thromboresistance by this test. Poly (2-hydroxyethyl methacrylate-ethyl methacrylate (HEMA/EMA) copolymers were examined along with pure HEMA and EMA grafts. At two weeks implantation, intermediate HEMA/EMA copolymers were found to have the least thrombus accumulation of any of the polymers in this series. EMA grafted rings were highly thrombogenic. The results from these studies indicate that the sensitivity of the vena cava ring test for detecting certain differences in polymer structure is poor. Also, the significance of the vena cava ring test for evaluating materials for use in contact with flowing human blood is questionable, based upon comparisons of results for similar materials tested in other blood compatibility evaluation systems.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"313-23"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11912162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
In vitro cytotoxicity and in vivo acute responses to some amino acid copolymers and their esters. 一些氨基酸共聚物及其酯的体外细胞毒性和体内急性反应。
Journal of bioengineering Pub Date : 1978-06-01
O Sudilovsky, D F Gibbons, R L Martin, L R Friedman
{"title":"In vitro cytotoxicity and in vivo acute responses to some amino acid copolymers and their esters.","authors":"O Sudilovsky,&nbsp;D F Gibbons,&nbsp;R L Martin,&nbsp;L R Friedman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The present study was performed in order to establish if there is any correspondence between specific parameters of tissue reaction to implanted biomedical materials and in vitro cytotoxicity. The presence of various types of inflammatory cells and/or necrosis in rats implanted subcutaneously with a series of 42 alpha-amino acid copolymers and their esters was compared with their in vitro toxic effects, as determined by an agar overlay technique. Only necrosis appeared to correlate with reactions scored as strongly positive by tissue culture procedures. Future studies with slightly toxic materials should assess if tissue culture methods could be helpful in predicting other levels of reaction at the polymer-tissue interface.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"325-32"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11911976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Polymer modification and blood compatibility. 高分子改性与血液相容性。
Journal of bioengineering Pub Date : 1978-06-01
J M Courtney, G B Park, C R Prentice, J F Winchester, C D Forbes
{"title":"Polymer modification and blood compatibility.","authors":"J M Courtney,&nbsp;G B Park,&nbsp;C R Prentice,&nbsp;J F Winchester,&nbsp;C D Forbes","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two procedures have been examined for altering the blood compatibility of copolymers of dimethylaminoethyl methacrylate, where blood compatibility has been measured by the recalcification time of platelet rich plasma. The improvement in blood compatibility of a copolymer of dimethylaminoethyl methacrylate and methyl methacrylate resulting from contact with heparin has been shown to be dependent on both copolymer composition and the method of polymerization. The hydrophilicity of a copolymer of dimethylaminoethyl methacrylate and acrylonitrile has been altered by reaction with ethylene oxide gas. The relationship between time of exposure to ethylene oxide gas. The relationship between time of exposure to ethylene oxide gas and clotting time indicates a dependence of compatibility on copolymer hydrophilicity.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"241-9"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11912156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An accurate data collection method for spatial motion using a sonic digitizer. 一种利用声波数字化仪对空间运动进行精确数据采集的方法。
Journal of bioengineering Pub Date : 1978-06-01
Y Youm, J A Nichols, A E Flatt
{"title":"An accurate data collection method for spatial motion using a sonic digitizer.","authors":"Y Youm,&nbsp;J A Nichols,&nbsp;A E Flatt","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An accurate collecting method for spatial displacement data utilizing a sonic digitizer which works electronically and acoustically is described. The sequence of the operation of the digitizer system is explained. As an application, the study of elbow flexion-extension is presented. Finally, operational precautions for using this system are discussed.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"359-67"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11911980","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of diagnostic Doppler ultrasonics in Brazil. 多普勒超声诊断在巴西的发展。
Journal of bioengineering Pub Date : 1978-06-01
E R Greene, K F Jedlicka, J C Machado, M M Werneck, C J Hartley
{"title":"Development of diagnostic Doppler ultrasonics in Brazil.","authors":"E R Greene,&nbsp;K F Jedlicka,&nbsp;J C Machado,&nbsp;M M Werneck,&nbsp;C J Hartley","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"229-30"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11912154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Experimental myringoplasty. 实验性鼓膜成形术。
Journal of bioengineering Pub Date : 1978-06-01
R Baarsma, J Feijen, J Houthoff
{"title":"Experimental myringoplasty.","authors":"R Baarsma,&nbsp;J Feijen,&nbsp;J Houthoff","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Different materials were compared as implants in performing a myringoplasty on rats immediately after making a total perforation, (autologous fascia, homologous tympanic membrane, homologous collagen, heterologous collagen, heterologous amnion and proplast). As a reference one group of rats had no myringoplasty done after perforating their drums. The animals were examined regularly, then killed after 40 and 64 weeks. Macroscopically and microscopically proplast and homologous collagen were very inferior to homograft tympanic membrane and autologous fascia. The best results were obtained both macroscopically and histologically with heterologous collagen and heterologous amnion.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"251-7"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11912157","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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