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Tissue ingrowth in porous acrylic cement. 多孔丙烯酸水泥中组织向内生长。
Journal of bioengineering Pub Date : 1978-06-01
A M Rijke, W A Jesser, J D Deck, E M Wright
{"title":"Tissue ingrowth in porous acrylic cement.","authors":"A M Rijke, W A Jesser, J D Deck, E M Wright","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"333-9"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11911977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Oxygen exchange in silicone rubber capillaries. 硅橡胶毛细血管中的氧交换。
Journal of bioengineering Pub Date : 1978-06-01
F G Heineken, P K Predecki, G F Filley
{"title":"Oxygen exchange in silicone rubber capillaries.","authors":"F G Heineken,&nbsp;P K Predecki,&nbsp;G F Filley","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Capillaries of 7 and 12.5 mu diameter have been fabricated in silicone rubber. Whole blood treated with heparin has been perfused through these capillaries. Under flowing conditions, no clotting or other clumping effects have been observed and red cells appear to maintain a constant velocity. Oxygen transfer data to and from saline perfusing the 12.5 mu diameter capillaries have been obtained in order to determine how rapidly O2 will permeate the silicone rubber film. The data indicate that the capillaries simulate lung tissue oxygen exchange and will allow for the first time the experimental determination of oxygen exchange kinetics in flowing whole blood.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"195-204"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11912152","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel filler free silicone rubber biomaterial. II. Radiation chemical and physical evaluation. 一种新型无填料硅橡胶生物材料。2辐射化学和物理评价。
Journal of bioengineering Pub Date : 1978-06-01
A S Chawla
{"title":"A novel filler free silicone rubber biomaterial. II. Radiation chemical and physical evaluation.","authors":"A S Chawla","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hexamethylcyclotrisiloxane was polymerized at 60 degrees C by gamma radiation to yield filler free silicone rubber (FFSR). The G (crosslinking) value of 23.5 was found for the FFSR polymerized for 4 hours, compared to about 2 for the pure polydimethylsiloxane (PDMS). The sol fractions for both FFSR and cross-linked PDMS varied between 5-7%. The FFSR and the cross-linked PDMS both had tensile strength of about 1 kg per cm2 but FFSR was not brittle and could be extended as much as 500% before breaking. It is believed that the marked improvement in physical properties of FFSR is due to the formation of domains of highly cross-linked material which act as \"internal filler\".</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"231-40"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11912155","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A model for evaluating the ocular contusion injury potential of propelled objects. 一种评估推进物眼挫伤损伤潜力的模型。
Journal of bioengineering Pub Date : 1978-06-01
R E Berger
{"title":"A model for evaluating the ocular contusion injury potential of propelled objects.","authors":"R E Berger","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The existing data on experimental ocular contusion were analyzed in terms of a simple mathematical model which predicts the maximum contact force between the eye and the impacting projectile. It was shown that this force was related to the injury producing mechanism, eyeball expansion, which was widely advocated in the literature. The effect of loading rate was also accounted for in the model. A dimensional analysis allowed previous experimental data to be used to generate tolerance curves for ocular injury. The agreement between the prediction of the model and previous subjective opinions of a panel of ophthalmologists was considered to be satisfactory. When the model was used to predict the hazard potential of projectile toys which presently exist in the market place, it was found that the contusive injury producing capability of these products covered the full range from safe to hazardous.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"345-58"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11911979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Aortic valve mechanics--Part I: material properties of natural porcine aortic valves. 主动脉瓣力学第1部分:天然猪主动脉瓣的材料特性
Journal of bioengineering Pub Date : 1978-06-01
Y F Missirlis, M Chong
{"title":"Aortic valve mechanics--Part I: material properties of natural porcine aortic valves.","authors":"Y F Missirlis,&nbsp;M Chong","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A new methodology has been developed whereby the inhomogeneous and anisotropic aspects of an irregularly surfaced organ component have been incorporated in establishing the material properties of its tissue. Specifically the direction-dependent post-transition elastic moduli have been calculated from microtensile experiments for the porcine aortic valve leaflets with an average of ECIRC/ERAD = 3.2. Furthermore pressure-strain data have been measured for a grid of points on the surface of a porcine aortic valve and an isostrain map has been developed for P = 80 mm. Hg. These data are used for the stress analysis of porcine aortic valves which is the subject of a companion paper.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"287-300"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11912160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effect of polyurethane morphology on blood coagulation. 聚氨酯形态对血液凝固的影响。
Journal of bioengineering Pub Date : 1978-06-01
G J Picha, D F Gibbons
{"title":"Effect of polyurethane morphology on blood coagulation.","authors":"G J Picha,&nbsp;D F Gibbons","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A series of polyurethanes based on the hard segment MDI and soft segment PTMG were synthesized. The molecular weight of the PTMG was 730, 1000, and 2000, and ethylene diamine was used as chain extender. The fabrication process was varied so as to achieve the maximum disorder (nonequilibrium state) and maximum order, fully annealed. It was demostrated that the \"quenched\" non-equilibrium state reduces the rate of activation of the intrinsic systems, factor XII pathway, when compared to the fully annealed state. Platelet attachment is primarily affected by phase separation.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"301-11"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11912161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Transferred pulmonary surfactant film: chemical analysis and contact angle study. 转移肺表面活性物质膜:化学分析和接触角研究。
Journal of bioengineering Pub Date : 1978-06-01
L P Lee, J S Lee
{"title":"Transferred pulmonary surfactant film: chemical analysis and contact angle study.","authors":"L P Lee,&nbsp;J S Lee","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The Langmuir dip plate transfer technique was adapted to isolate the interfacial film formed at the surface of lung wash. The chemical analysis of the film showed that the weight ratio of lipid to protein of this surfactant film and its content of surface active substances were higher than those of lung wash. It was found that the wettability of the surfactant film could be simulated by a Dipalmitoyl lecithin and albumin film. When the surfactant film was transferred at condensed state (one of low air-lung-wash surface tension), we found the film exhibited a low critical surface tension which indicates the dominance of the lipid in the outer most layer of the film. On the other hand, insignificant amount of lipid was found in the film transferred at expanded state (one of high surface tension) and its surface behavior was shown to be similar to that of a protein film.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"259-67"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11784430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intra-articular implant of filamentous carbon fibre in the experimental animal. 丝状碳纤维在实验动物关节内的植入。
Journal of bioengineering Pub Date : 1978-06-01
R J Minns, M Flynn
{"title":"Intra-articular implant of filamentous carbon fibre in the experimental animal.","authors":"R J Minns,&nbsp;M Flynn","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effects of filling drilled holes and articular cartilage grooves in rabbit femora with 9 micrometer diameter filamentous carbon fibre in vivo were studied. The animals were killed at four weeks and five months and the medial and lateral femoral condyles removed and studied morphologically by gross and scanning electron microscopic examination, and histologically using hematoxylin and eosin, van Gieson, toluidine blue and safranin O staining techniques. Fibrous tissue appeared to surround the carbon fibre bundle and emerge at the surface in large organised bundles, overflowing to cover the surface adjacent to the hole defects. Fibrous tissue surrounds the carbon fibre bundle, and forms a new surface over grooves made in the articular cartilage of rabbits that were kept alive for five months, the tissue within the control grooves filled with disorganised fibrous tissue. There was very little foreign body reaction and the fibrous tissue appeared to grow parallel and surround the carbon fibre bundle.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 3-4","pages":"279-86"},"PeriodicalIF":0.0,"publicationDate":"1978-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11912159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The application of experimental design in bioengineering. 实验设计在生物工程中的应用。
Journal of bioengineering Pub Date : 1978-04-01
R L Kirkham, J A Austin
{"title":"The application of experimental design in bioengineering.","authors":"R L Kirkham,&nbsp;J A Austin","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The use of factorial designs in experimentation and the careful planning of the three basic phases of experimental projects, will maximize the reliable information from the experiment and minimize the cost and effort to the experimentor. The application of the principles of good experimental design are illustrated in a case study of experimentation which investigates a new mode of peritoneal dialysis.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 1-2","pages":"11-9"},"PeriodicalIF":0.0,"publicationDate":"1978-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11882455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A feasibility study for the use of a silastic gage as an in vivo muscle force transducer. 使用弹性计作为体内肌肉力传感器的可行性研究。
Journal of bioengineering Pub Date : 1978-04-01
A Seireg, W Gray
{"title":"A feasibility study for the use of a silastic gage as an in vivo muscle force transducer.","authors":"A Seireg,&nbsp;W Gray","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This study investigates the feasibility of utilizing silastic gages for in vivo dynamic muscle force measurement. The gastrocnemius muscle of a fifty-one pound black short hair dog was selected for the test. The study shows that such measurements can be reliably performed in vivo for short durations without interfering with the natural movement of the animal. The durability of the gage appears to be primarily limited by the biological rejection process at the gage site.</p>","PeriodicalId":75990,"journal":{"name":"Journal of bioengineering","volume":"2 1-2","pages":"159-66"},"PeriodicalIF":0.0,"publicationDate":"1978-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11882459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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