P J Meis, F H Hulcher, J C Rose, J Halberg, F Halberg
{"title":"Meal timing alters circadian rhythm of skin surface temperature in non-human primates.","authors":"P J Meis, F H Hulcher, J C Rose, J Halberg, F Halberg","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Circadian rhythms of skin surface temperature were demonstrated in a group of African green vervets. Alteration of the timing of a single daily meal of fixed caloric content resulted in a shift of the skin surface temperature acrophase in 7 of the 8 series. The timing of the individual temperature acrophases in relation to the light-dark cycle and the extent of acrophase shift in response to alteration of meal timing showed considerable variation between the individual animals studied.</p>","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"7 2","pages":"65-76"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18462082","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Chronobiologia, quo vadis? The first chronobiology course of the Italian Society for Chronobiology.","authors":"E Halberg, F Halberg","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"7 2","pages":"117-25"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18462081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B Tarquini, R Gheri, S Romano, A Costa, M Cagnoni, J K Lee, F Halberg
{"title":"Circadian variation of serum prolactin and TSH of women in health or with mammary carcinoma, fibroadenoma or fibrocystic mastopathy.","authors":"B Tarquini, R Gheri, S Romano, A Costa, M Cagnoni, J K Lee, F Halberg","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Prolactin and TSH were determined in serum samples obtained at 4-hourly intervals throughout a 24-hour span from healthy women and from women with fibrocystic mastopathy, fibroadenoma or carcinoma of the breast. Data were subjected to analysis by the population mean-cosinor method. Differences in circadian mesor of prolactin among the 4 groups were statistically significant (P < .01), with healthy women having the lowest value. Prolactin amplitude differences among the groups were of borderline statistical significance (P = .05), while no differences in circadian acrophase were apparent. No statistically significance differences in TSH circadian mesor, amplitude or acrophase could be demonstrated. Individual values from subjects with breast disease were compared with time-qualified tolerance intervals based on data from healthy subjects. If these results can be corroborated on larger populations, sampling about 3 hours after arising may best detect an abnormal serum prolactin elevation. Results from this and other studies indicate the need for multi-variable and multifrequency investigations of breast disease.</p>","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"7 2","pages":"101-15"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18462080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"International Cancer Research Workshop on \"Chronotherapy of cancer - a critical evaluation\" sponsored by the International Cancer Research Data Bank of the United States of America, and administered by the International Union Against Cancer.","authors":"E Haus, F Halberg, L E Scheving, H Simpson","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"6 2","pages":"67-107"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11268156","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Circadian rhythmicity in rat intestinal villus length and cell number.","authors":"N R Stevenson, S E Day, H Sitren","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Circadian rhythmicity has been reported in various small intestinal digestive-absorptive functions and in the mitotic activity of intestinal crypt cells. These functional activity rhythms and perhaps the mitotic rhythms are cued by the feeding schedule. We now report that circadian rhythms also occurred in both the villus height and cell number in rats maintained on morning or afternoon feeding schedules for 7 days. Villus width was constant. In afternoon-fed rats both villus height and cell number were 50% greater just before feeding than 12 h later. The amplitudes of the two rhythms in the morning fed rats were decreased, the general shape of the cycles were changed and the average number of cells was increased. These changes between morning and afternoon feeding are attributed to incomplete phase shifting due to an insufficient adaptation span for the morning fed rats. We conclude that circadian rhythms occurring in villus height and cell number are affected by the feeding schedule. Similarities to some previously reported functional rhythms suggest that fluctuations in cell number and/or villus length might be related to the functional changes.</p>","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"6 1","pages":"1-12"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11643821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interactions of endogenous rhythms during postnatal development. Observations of behaviour and polygraphic studies in one normal infant.","authors":"A Meier-Koll","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The spontaneous sleep-waking behaviour of a male infant, normal with respect to pregnancy, delivery and Apgar score, was observed continuously from birth till the first four months of life. Additionally sleep stages were registered polygraphically during several weeks. The infant was allowed to sleep and awake according to his own schedule. It could be demonstrated that the spontaneous sleep-waking behaviour was mainly driven by 3 endogenous rhythms : The Basic rest activity cycle with a period of about 50 minutes, a 4-hour cycle already established during the first 2 weeks of life and a circadian rhythm which developed during the second month of life. So far the presented results support earlier studies of Kleitman and Engelmann, Sterman and Hoppenbrouwers, Hellbrugge etc. The present study, however, gives further evidence, that these rhythms do not run independently, but constitute a system of interacting oscillators.</p>","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"6 3","pages":"179-89"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11759374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Halberg, E Halberg, D K Hayes, R D Smith, F Halberg, C S Delea, R S Danielson, F C Bartter
{"title":"Schedule shifts, life quality and quantity--modeled by murine blood pressure elevation and arthropod life span.","authors":"J Halberg, E Halberg, D K Hayes, R D Smith, F Halberg, C S Delea, R S Danielson, F C Bartter","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>During the span from 50 to 100 days and beyond, the male stroke-prone Okamoto rat develops systolic blood pressure measures in excess of 200 mm Hg. In the course of developing such a marked elevation in systolic blood pressure mean, this intermittently handled male Okamoto rat exhibits a statistically significant circadian rhythm with large amplitude. This amplitude may represent, at least in part, a response to intermittent handling; it is several times larger than the amplitude for spontaneously mesor-hypertensive (but not stroke-prone) female animals of the same age.</p>","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"7 1","pages":"17-64"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11759377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Diurnal circadian rhythms of renal function and electrolyte excretion in heart failure.","authors":"L G Wesson","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Diurnal cycles of glomerular filtration rate (GFR), effective renal plasma flow (ERPF), and of excretion rates of sodium, potassium, magnesium, chloride and phosphate were measured in a 22 year old man with moderately severe heart failure under standardized conditions. Cycles of GFR, ERPF and excretion of potassium, chloride, and phosphate were indistinguishable from those of normals. The phases of the sodium and probably the magnesium excretory cycles were reversed from normal. The significance of some of the observations is discussed.</p>","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"6 2","pages":"109-17"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11780655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Rhythmometry gauges treatment of mesor-hypertension in the seventh and eight decades of life.","authors":"R Engel, F Halberg, W Nelson, F C Bartter","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Autorhythmometry of blood pressure by an individual over an age-span of 67 to 72 years showed a strong circadian rhythm superimposed upon significant circaseptan and circannual rhythms. Automatic BP monitoring with an Arteriosonde throughout 24-hour spans on 4 separate occasions, before and during treatment, also indicated a prominent circadian BP rhythm and a treatment-related reduction in circadian mesor. The concept of a blood pressure mesor reference for the antimesor-hypertensive treatment constitutes a valuable guideline in the control of \"familial\" mesor-hypertension.</p>","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"6 3","pages":"163-78"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11759375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Circadian rhythm of cholesterol biosynthesis: dietary regulation in the liver and small intestine of hamsters.","authors":"K J Ho","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Sixty three hamsters were divided into two groups which were exposed to the same rigid lighting schedule (06(00)--18(00)) but fed at different time intervals (18(00)--22(00), and 08(00)--12(00), respectively) for five weeks. The cholesterol synthetic activity was then determined in liver, gastrointestinal tract, and kidney by in vivo incorporation of (1--14C)-acetate into cholesterol at different hours of the day. A remarkable circadian rhythm of the activity was found in the liver and small intestine, but not in other organs. Regardless of the lighting schedule, the nadir occurred, in both groups, always at the end of the fasting period and the peak four to six hours after feeding. The study clearly indicated the major role of diet in regulation of such phenomenon.</p>","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"6 1","pages":"39-50"},"PeriodicalIF":0.0,"publicationDate":"1979-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11643823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}