{"title":"21 Corticosteroid Administration Schedules and Differences in Circadian Behavior of Human Circulating Eosinophils","authors":"G. Cornelissen, C. Bingham, F. Halberg","doi":"10.1159/000410961","DOIUrl":"https://doi.org/10.1159/000410961","url":null,"abstract":"","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"7 1","pages":"120-125"},"PeriodicalIF":0.0,"publicationDate":"1984-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000410961","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"64829664","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Y Touitou, C Touitou, G Charransol, A Reinberg, J Thomas, A Bogdan, C Barthelemy, P Desgrez
{"title":"Alterations in circadian rhythmicity in calcium oxalate renal stone formers.","authors":"Y Touitou, C Touitou, G Charransol, A Reinberg, J Thomas, A Bogdan, C Barthelemy, P Desgrez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The circadian (circannual for oxalic acid) variations of 13 urinary variables (volume, creatinine, calcium, oxalic acid, glycolic acid, 17-ketosteroids, 17-hydroxycorticosteroids, phosphates, urea, uric acid, chloride, sodium, and potassium) have been documented in 7 calcium oxalate renal stone formers and 7 healthy men (control group). Urine was collected every 4 h over a period of 24 h. All subjects had the same synchronization: diurnal activity from 07(00) to 23(00) +/- 1 h and nocturnal rest; meals were given at fixed clock hours (08(00), 12(30) and 20(00) +/- 1 h). A statistically-significant rhythm (p less than 0.05) was validated for all variables except urea and calcium in healthy men. In renal stone formers, 6 variables (calcium, oxalic acid, and glycolic acid in particular) had no detectable circadian rhythm. However, a periodicity of c. 8 h (ultradian rhythm) was demonstrated for calcium and oxalic acid with peaks being located around 02(00), 10(00), and 18(00). No circannual variations in oxalic acid output could be observed. The present study shows an alteration of the periodicity of calcium and oxalic metabolisms, i.e. the loss of a circadian (24-h) rhythm and the occurrence of an ultradian rhythm of 8 h. The risk of calcium-oxalate crystallisation appears thus greater at 02(00), 10(00), and 18(00). Furthermore, any study dealing with oxalic acid excretion should state the season of urine collection when comparing renal stone formers and healthy subjects, as significant differences in oxaluria may appear during the summer months and not during the rest of the year.</p>","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"8 3","pages":"175-92"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17912987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Human circannual rhythms over a broad spectrum of physiological processes.","authors":"F Halberg, M Lagoguey, A Reinberg","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"8 4","pages":"225-68"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17698033","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Period lengthening of human circadian rhythms by lithium carbonate, a prophylactic for depressive disorders.","authors":"A Johnsson, W Engelmann, B Pflug, W Klemke","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of lithium carbonate on the circadian system of man was studied. Four out of eight volunteers living without time cues in isolated huts in the arctic showed a lengthening of the periods of the body temperature rhythm, activity rhythm, and sleep/wakefulness rhythm by c. 1 h. Four of the participants did not show a change in the periods between the placebo and lithium ingestion phases. Two subjects who did not receive lithium salt showed internal desynchronization between the temperature rhythm and the sleep/wakefulness rhythm. Extreme isolation in bunkers is not necessary to allow free running of the circadian system in man. The sleep/wakefulness rhythm, which is very easy to record, was a reliable indicator of the circadian system in the internally-synchronized state.</p>","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"8 3","pages":"129-47"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17912985","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Altered circadian periodicities in oral temperature and mood in men on an 18-hour work/rest cycle during a nuclear submarine patrol.","authors":"P Naitoh, A N Beare, R J Biersner, C E Englund","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A group of nuclear submariners was studied to examine whether an 18-h routine (6-h on, 12-h off watch) during a 10-week submerged patrol affected the 24-h circadian rhythm in oral temperature, Thayer's activation, Mood 'Activity' (MA) and Mood 'Happiness' (MH). They were observed during three phases of the patrol: Phase 1, the beginning 8-day period; Phase 2, the middle of the voyage; and Phase 3, the last 7-8 day period. The group-synchronized 24-h rhythm in oral temperature disappeared during Phase 3. The group-synchronized 24-h rhythms in Thayer's activation and in MA and MH disappeared during Phases 2 and 3. A group-synchronized 18-h rhythm was not produced in any of the variables in any phase, except MH during Phase 2. Periodicity analysis of the individuals' data showed that a loss of 24-h rhythmicity in oral temperature was due not only to reduced circadian amplitude but also to a dispersion of Time of Peak (TOPs). Loss of 24-h rhythm in 'Activation', 'Happiness', and 'Activity' was predominantly due to a wider dispersion of TOPs. The 18-h routine did appear to exert a small modulating effect on rhythmic activity in the variables examined in this study. Since the sleep/wakefulness cycle was well entrained by the 18-h routine, the submariners experienced a spontaneous internal desynchronization between the activity cycle and the cycles or oral temperature and psychological states. The performance and health consequences of this chronic dyschronism have yet to be explored. We suggest further research to determine the usefulness of an index of synchronization among the physiological and psychological variables, and the relationship of the desynchronizing effects to performance.</p>","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"8 3","pages":"149-73"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17912986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Altered circadian periodicities in oral temperature and mood in men on an 18-hour work/rest cycle during a nuclear submarine patrol.","authors":"P. Naitoh, A. Beare, R. Biersner, C. Englund","doi":"10.21236/ADA102590","DOIUrl":"https://doi.org/10.21236/ADA102590","url":null,"abstract":"A group of nuclear submariners was studied to examine whether an 18-h routine (6-h on, 12-h off watch) during a 10-week submerged patrol affected the 24-h circadian rhythm in oral temperature, Thayer's activation, Mood 'Activity' (MA) and Mood 'Happiness' (MH). They were observed during three phases of the patrol: Phase 1, the beginning 8-day period; Phase 2, the middle of the voyage; and Phase 3, the last 7-8 day period. The group-synchronized 24-h rhythm in oral temperature disappeared during Phase 3. The group-synchronized 24-h rhythms in Thayer's activation and in MA and MH disappeared during Phases 2 and 3. A group-synchronized 18-h rhythm was not produced in any of the variables in any phase, except MH during Phase 2. Periodicity analysis of the individuals' data showed that a loss of 24-h rhythmicity in oral temperature was due not only to reduced circadian amplitude but also to a dispersion of Time of Peak (TOPs). Loss of 24-h rhythm in 'Activation', 'Happiness', and 'Activity' was predominantly due to a wider dispersion of TOPs. The 18-h routine did appear to exert a small modulating effect on rhythmic activity in the variables examined in this study. Since the sleep/wakefulness cycle was well entrained by the 18-h routine, the submariners experienced a spontaneous internal desynchronization between the activity cycle and the cycles or oral temperature and psychological states. The performance and health consequences of this chronic dyschronism have yet to be explored. We suggest further research to determine the usefulness of an index of synchronization among the physiological and psychological variables, and the relationship of the desynchronizing effects to performance.","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"8 3 1","pages":"149-73"},"PeriodicalIF":0.0,"publicationDate":"1983-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"67984632","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Long-term control of swelling after maxillo-facial surgery: a study of circaseptan reactive periodicity.","authors":"L Pöllmann, G Hildebrandt","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The course of swelling after maxillo-facial surgery was investigated by measuring the distance from the tragus to the pogonium. Post-operative distension does not diminish progressively, but decreases in a circaseptan rhythm. Antiphlogistic agents reduce the extent of the post-surgical swelling, but they also disturb the circaseptan reactive periodicity. This could indicate either an acceleration of the wound healing or a damping down or disturbance of the regeneration mechanisms of the organism. Although this question is of considerable clinical importance, present research has not yet provided an answer.</p>","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"8 2","pages":"105-14"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18157393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The application of variance analysis to the study of biological rhythms of known periods.","authors":"H Marotte, J Timbal","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This paper describes a statistical technique which permits study of, for example, complex biological rhythms with a known fundamental period. This technique uses the principles of variance analysis. The main calculation phases are: the regression calculation on a periodic time function; the study (by variance analysis) of the validity of the mathematical model; the study of the parallelism between subjects; and, finally, the study of the significance of each harmonic component. The calculation is completed by determining confidence intervals: those of the harmonic function parameters, followed by those of the function extremes.</p>","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"8 2","pages":"63-82"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18157395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Circadian rhythms in mouse epidermis: variation in the numbers of basal and differentiating cells, cell density, and cell loss.","authors":"O P Clausen, E Thorud, S L Kauffman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In histologic sections from hairless mouse epidermis, the total epidermal cell number and the numbers of basal and differentiating cells were determined per unit length, and cell density was calculated. Sampling was made every 2 h during 2 successive 24-h spans. All parameters showed circadian changes during both 24-h spans. The cell numbers per unit length and the cell density showed both high values around 12(00), some hours subsequent to the peak of mitotic activity. The loss rate of epidermal nucleated cells was calculated from first harmonic sine curves fitted to the circadian changes in total epidermal cell number and to the mitotic rate. The loss rate showed a circadian rhythm with increased values from after 16 00 to after 00(00). This implies that there is a circadian variation in the transition of differentiating cells into horny materials, and hence in cell differentiation.</p>","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"8 2","pages":"83-93"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18157207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Circadian variation in the susceptibility of mouse epidermis to chemical carcinogens.","authors":"O H Iversen, S L Kauffman","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75936,"journal":{"name":"International journal of chronobiology","volume":"8 2","pages":"95-6"},"PeriodicalIF":0.0,"publicationDate":"1982-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18157208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}