American Journal of Phytomedicine and Clinical Therapeutics最新文献

{"title":"Editorial Note on Lanthanum (III) TriggersAtrbohD and Jasmonic Corrosive Ward Fundamental Endocytosis in Plants","authors":"John D. Edwards","doi":"10.36648/2321-2748.21.9.40","DOIUrl":"https://doi.org/10.36648/2321-2748.21.9.40","url":null,"abstract":"","PeriodicalId":7592,"journal":{"name":"American Journal of Phytomedicine and Clinical Therapeutics","volume":"89 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84477518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phytochemical and Antioxidant Analysis of Medicinal and Food Plants","authors":"J. Dane","doi":"10.36648/2321-2748.21.9.35","DOIUrl":"https://doi.org/10.36648/2321-2748.21.9.35","url":null,"abstract":"","PeriodicalId":7592,"journal":{"name":"American Journal of Phytomedicine and Clinical Therapeutics","volume":"92 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77998955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Learning and Memory Enhancing Effects of BacoLive andreg; (An Enriched Composition of Bacopa monnieri Extract) in Scopolamine Induced Memory Impaired Mice","authors":"A. Sudhakar, J. Shantakumar, Prasad Cp, Joseph Mv","doi":"10.36648/2321-2748.21.9.32","DOIUrl":"https://doi.org/10.36648/2321-2748.21.9.32","url":null,"abstract":"Objective: The objective of this study was to evaluate the learning and memory enhancement activity of BacoLive® (a composition enriched with bacosides from Bacopa monnieri) in various experimental models i.e., passive shock avoidance test, Y- maze test and novel object recognition test. Methodology: BacoLive® was administered for 7 days at the dose of 100, and 200 mg/kg to mice in passive shock avoidance test, Y-Maze test and in novel object recognition test. Scopolamine (0.5 mg/kg) was used to induce memory (amnesia) loss and piracetam (200 mg/kg) served as reference standard. After 7 days, cognitive and memory scales were measured as per standard test protocols. Results: In the passive shock test for memory, BacoLive ® reduced the latency to reach the shock free zone compared to amnesia induced group. In the Y-maze test, the number of arm entries failed to memorize the new space was decreased with BacoLive ® group compared to amnesia induced group. In the new object recognition test, BacoLIve ® improved the percentage preference for new object recognition compared to amnesia induced group. Conclusion: Based on the present study and findings, BacoLive® demonstrated learning and memory enhancing effects and reversed memory loss effects induced by scopolamine in mice, which suggest its beneficial role in conditions associated with memory and learning dysfunctions. Study indicates that bacopa extract justifies its traditional use in Ayurveda for memory related complications associated with neuro degeneration and stress.","PeriodicalId":7592,"journal":{"name":"American Journal of Phytomedicine and Clinical Therapeutics","volume":"245 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74123260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Editorial Note on Antibiotics against Different Bacterial Isolates from Skin infection","authors":"Michael John Smith","doi":"10.36648/2321-2748.21.9.12","DOIUrl":"https://doi.org/10.36648/2321-2748.21.9.12","url":null,"abstract":"","PeriodicalId":7592,"journal":{"name":"American Journal of Phytomedicine and Clinical Therapeutics","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80857946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Herbal Small Molecules Turned into Sustained Release Hydrogels","authors":"Vinay Kumar","doi":"10.36648/2321-2748.21.9.28","DOIUrl":"https://doi.org/10.36648/2321-2748.21.9.28","url":null,"abstract":"","PeriodicalId":7592,"journal":{"name":"American Journal of Phytomedicine and Clinical Therapeutics","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91321579","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The use of herbal products during pregnancy: which is the risk perception","authors":"A. Vitalone, Olta Allkanjari, Federico Durazzi, M. Guizzetti, Vincenzo Ale, ri Annabella Vitalone","doi":"10.36648/2321-2748.9.1.2","DOIUrl":"https://doi.org/10.36648/2321-2748.9.1.2","url":null,"abstract":"The aim of the study was to assess women habits during pregnancy, the prevalence of use of herbal products and the awareness about the related risk of adverse reactions. A total of 279 interviewees, at Polyclinic Umberto I (Rome, Italy), completed the questionnaire that examined descriptive and analytical aspects about herbal products. The majority quit smoking and drinking alcohol, but consumed regularly herbal products, often associated with drug therapies. Pregnant women considered herbal products less dangerous than other medications, even if some dermatological and gastrointestinal adverse reactions were reported. Gynecologist and herbalist represent the primary source of information about herbal products, while the most common place of purchase is the pharmacy. Pregnant women appear mindful about the risks of smoking, alcohol and medications. On the contrary, their knowledge about the risk/ benefit profile of herbal products is limited. Therefore, information strategies and surveillance programs about the safety of herbal products should be implemented in the context of public health.","PeriodicalId":7592,"journal":{"name":"American Journal of Phytomedicine and Clinical Therapeutics","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75553133","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Quality of Different Brands of Metronidazole Available in Jimma Town, South West Ethiopia: A Cross-Sectional PharmaceuticalQuality Study","authors":"Teshome Sosengo, Tesfaye Mohammed, Ramanjireddy Tatiparthi","doi":"10.36648/2321-2748.9.2.10","DOIUrl":"https://doi.org/10.36648/2321-2748.9.2.10","url":null,"abstract":"Background: Poor quality medicines include substandard and falsified (i.e., counterfeited) medicines. WHO report of 2017 estimates that the rates of substandard and falsified medical products in low- and middle-income countries is approximately 10.5% with an estimated spend of US$ 30.5 billion. Objective: The purpose of the study is to assess the quality of different brands of metronidazole available in Jimma town, Oromia region, South West Ethiopia. Methods: Cross-sectional study was conducted in Jimma town, Oromia regional state, Ethiopia. The study was conducted from May 03 – July 30, 2018. Samples were collected using convenience sampling technique. The samples were analyzed using a methods specified in British Pharmacopoeia 2013 and United States Pharmacopoeia 2015. The assay result of all the seven brands of metronidazole and dissolution test result of the three brands of metronidazole capsules was entered to statistical package for social sciences software version 24.0 for windows. Then, one way analysis of variance was performed using Tukey test to determine whether there exists significant difference in assay and dissolution test results within and among the brands of the respective dosage forms (p<0.05). Results and Discussion: The quality of brands (three Metronidazole capsules and four Metronidazole injections brands) of Metronidazole was assessed based up on a method specified in BP 2013 and USP 2015. All the seven brands of Metronidazole analyzed for quality passed identity test specification of BP 2013. The three brands of Metronidazole capsules passed weight uniformity and dissolution test specification of USP 2015. The seven brands of Metronidazole passed assay (i.e., drug content) test specification of USP 2015. The highest percentage of drug content, 107.81% and 105.56%, obtained for Metronidazole (generic) (capsule), Nirmet (injection) respectively. However, statistical comparison of assay of respective brands of the respective dosage forms at 95% confidence interval indicates that there exists significant difference in assay within and among the brands of the respective dosage forms (p<0.05). All the four brands of Metronidazole injections passed USP 2015 limit for Endotoxin, Endotoxin limit < 0.35 Eu/ml. Two brands of Metronidazole injection, Aldezol and Metris, failed sterility test from the four brands of Metronidazole injections included in the study and hence of poor quality. The pH of Metronidazole injections were within BP 2013 specification range. Conclusion: The result of the current study revealed that there was incidence of poor quality Metronidazole in Jimma town. Therefore, post marketing quality assessment should be performed routinely to determine quality status of the drug on market.","PeriodicalId":7592,"journal":{"name":"American Journal of Phytomedicine and Clinical Therapeutics","volume":"17 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78233050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Review on the Medicinal Plant:Indian Calosanthes","authors":"Jain Pk, S. Arora, Y. Pounikar","doi":"10.36648/2321-2748.9.3.12","DOIUrl":"https://doi.org/10.36648/2321-2748.9.3.12","url":null,"abstract":"Therapeutic properties of Indian Calosanthes plant (Oroxylum indicum L. Kurz) are known for hundreds of years to various civilizations of the world. Therapeutic explorations of medicinal properties of Oroxylum indicum have been taken place mostly after the middle of the 20th century. In the present review, we discuss the efforts have been made to summarize different aspects of scientific studies on this medicinal plant. Scientific evidences are available on various medicinal aspects i. e. anti-microbial, anti-diabetic, hepato-protective, anti-inflammatory, anti-carcinogenic, immunomodulatory, nephro-protective, cardio-protective, etc. to name a few. Most of these evidences are based on in-vitro and experimental studies.","PeriodicalId":7592,"journal":{"name":"American Journal of Phytomedicine and Clinical Therapeutics","volume":"158 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78591782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Protective Effects of Delonix regia Leave Extract on Sodium Arsenite-Induced Hepatotoxicity in Rats","authors":"C. Madu, B. Inyang, K. C. Nwachukwu, Maxwell M. Nwegbu, L. A. Alli, Michael P. Okoh","doi":"10.36648/2321-2748.9.3.15","DOIUrl":"https://doi.org/10.36648/2321-2748.9.3.15","url":null,"abstract":"Nature provides rich sources of structurally diverse phytochemicals with medicinal relevance and biological activities. Sodium arsenite has been recognized as a worldwide health concern due to its teratogenicity effects on animals. Natural plants are considered as a possible protective agent against arsenic induced toxicity. The aim of this study was to investigate the protective effects of Delonix regia leave extracts on sodium arsenite induced hepatotoxicity in rat. Animals were randomly divided into six groups of five per group. Group A (control) received distilled water for fourteen (14) days. Group B received 2.5 mg/kg body weight Sodium Arsenite, group C received 100 mg/kg of leave extract and 2.5 mg/kg of sodium arsenite, Group D received 400 mg/kg of leave extract and 2.5 mg/kg of sodium arsenite, Group E received 100 mg/kg of leave extract, Group F received 400 mg/kg of leave extract only. On the fourteen day all the animals were sacrificed. Biochemical parameters such as plasma Alanine amino transferase (ALT), Aspartate amino transferase (AST) Alkaline phosphate (ALP) and gamma glutamyl transferase (GGT) total protein (TP) were evaluated. Sodium arsenite in rat triggers significant increase in ALT, AST, ALP, TP, and GGT (p<0.05 level). Upon treatments with Delonix regia leave extract, it decreases the concentration of GGT, AST and ALP compared to the negative control. Group treated with the extract alone showed no adverse effects on the liver parameters. Results from this study suggest that, the administration of Delonix regia leave extract confer some protective effects on the liver.","PeriodicalId":7592,"journal":{"name":"American Journal of Phytomedicine and Clinical Therapeutics","volume":"16 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85540356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Homoeopathy in the Treatment of Diabetes: A Review","authors":"S. Monika, S. Shilpi, Verma Digvijay","doi":"10.36648/2321-2748.9.2.8","DOIUrl":"https://doi.org/10.36648/2321-2748.9.2.8","url":null,"abstract":"Diabetes is one of the most fearsome concerns of the modern world. As the man has evolved he has tried to ease his life with inventions and technologies. These have led to unfit lifestyle changes and have caused a havoc on his health. The unhealthy lifestyle has resulted in various diseases one of which is diabetes. Diabetes is the inability of the body to process glucose leading to an increased level of glucose in the blood while the cells are deprived of it. A lot of work has been done and is still under process to curb the prevalence of this disorder. Homoeopathy is one such area of medicine that has had some success in the treatment of diabetes. Homoeopathy uses natural materials such as plants, animals, minerals to prepare medicines from. Plants form a major portion of homoeopathic medicines. Plants such as Syzygium jambolanum, Gymnema sylvestre, etc. have long been used to treat diabetes traditionally as well as in homoeopathy. These plants act in reducing the blood glucose level. It is therefore important that we focus more and more research on such easily and naturally available materials. It will not only reduce the load on pharma companies but will also make health care available to more and more people.","PeriodicalId":7592,"journal":{"name":"American Journal of Phytomedicine and Clinical Therapeutics","volume":"39 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75947653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}