Gynecologic investigation最新文献_第6页

Placental antigens and fetoproteins in the urine of rats - indicators of resorption of conceptuses. 大鼠尿液中的胎盘抗原和胎儿蛋白——胎儿吸收的指标。

Gynecologic investigation Pub Date : 1975-01-01 DOI: 10.1159/000301524

J H Boss, T Dishon, E Rosenmann

引用次数: 0

Binding interactions of progesterone and other C21 steroids with rat uterine cytosol. 黄体酮和其他C21类固醇与大鼠子宫细胞质的结合相互作用。

Gynecologic investigation Pub Date : 1975-01-01 DOI: 10.1159/000301523

B A Booth, A E Colás

引用次数: 11

Hormonal steroids: effects on the vascular system. 激素类固醇:对血管系统的影响。

Gynecologic investigation Pub Date : 1975-01-01 DOI: 10.1159/000301530

J Solash, R Perez, J S Keates, N Ramasamy, H Stein, D Troyansky, E Ateyeh, J R Jones, S Srinivasan, P N Sawyer

{"title":"Hormonal steroids: effects on the vascular system.","authors":"J Solash, R Perez, J S Keates, N Ramasamy, H Stein, D Troyansky, E Ateyeh, J R Jones, S Srinivasan, P N Sawyer","doi":"10.1159/000301530","DOIUrl":"https://doi.org/10.1159/000301530","url":null,"abstract":"An increase in the incidence of thromboembolic disorders has been associated with oral contraceptive use, though the causative mechanisms remain unclear. Our studies indicate that the contraceptive steroids, irrespective of the intermediary metabolic processes involved, cause changes in the surface charge characteristics of the blood vessel wall and blood cells in the following cases: (i) in experiments using dogs, the hormonal steroids result in a greater reduction in the pore surface charge of veins than in arteries; (ii) in rats, the current induced mesenteric occlusion times are significantly lowered following administration of combined contraceptives steroids; (iii) in humans, the electrophoretic mobilities of erythrocytes and platelets from women taking Ovral and Demulen are lower than in controls, and (iv) there is no significant alteration of plasma coagulation times of women who are on injectable progestin therapy. Demulen and Ovral appear to result in a slight decrease in activated partial thromboplastin times compared to controls.","PeriodicalId":75889,"journal":{"name":"Gynecologic investigation","volume":"6 6","pages":"329-36"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000301530","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12388736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 4

Biochemistry and physiology of oviductal secretions. 输卵管分泌物的生物化学和生理学。

Gynecologic investigation Pub Date : 1975-01-01 DOI: 10.1159/000301520

S L Stone, C D Hamner

引用次数: 33

Effects of prostaglandins on oviductal motility and egg transport. 前列腺素对输卵管运动和卵子运输的影响。

Gynecologic investigation Pub Date : 1975-01-01 DOI: 10.1159/000301516

C H Spilman, M J Harper

{"title":"Effects of prostaglandins on oviductal motility and egg transport.","authors":"C H Spilman, M J Harper","doi":"10.1159/000301516","DOIUrl":"https://doi.org/10.1159/000301516","url":null,"abstract":"The effects of prostaglandins (PGs) on muscular activity of the oviductal isthmus and on the rate of tubal egg transport are reviewed. In consideration of the available data a mechanism by which PGs contribute to the physiological control of egg transport is suggested. In vivo experiments have demonstrated that E-series PGs relax while F-series PGs stimulate muscular activity of the oviduct in humans, subhuman primates and rabbits. These effects are mutually antagonistic. The response of oviductal muscle to PGs appears to be affected by ovarian steroids; progesterone increases the response to PGE1 and decrease the response to PGF2alpha. Oviductal tissue concentrations of PGF increase in a distal to proximal sequence following ovulation-induction in the rabbit. Also, proximal isthmus binding of PGE1 t tended to be greater in 72-hour pregnant rabbits than in estrous rabbits, while binding of PGF2alpha was greater in estrous than in 72-hour pregnant animals. It is suggested that the preovulatory increase in ovarian estradiol secretion stimulates PGF synthesis in the oviductal tissue in a sequential fashion, the peak value occurring when the oviductal isthmus is most sensitive to stimulation by PGF2alpha. The changes in tissue concentration of PGF and in sensitivity to PGF2alpha could contribute to occlusion of the isthmus and prevent premature passage of eggs into the uterus. An increase in ovarian progesterone secretion after ovulation may decrease tissue PGF, decrease the response to PGF2alpha stimulation, and increase the response to PGF1. These changes may then allow a progressive movement of eggs through the isthmus into the uterus. Several questions regarding this proposed mechanism remain unanswered.","PeriodicalId":75889,"journal":{"name":"Gynecologic investigation","volume":"6 3-4","pages":"186-205"},"PeriodicalIF":0.0,"publicationDate":"1975-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1159/000301516","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11997364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 110

Isolation and characterization of 5alpha-pregnane-3,20-dione and progesterone in pepipheral blood of pregnant women. measurement throughout pregnancy. 孕妇外周血中5 -孕酮-3,20-二酮和孕酮的分离与鉴定。怀孕期间的测量。

Gynecologic investigation Pub Date : 1975-01-01

L Milewich, C Gomez-Sanchez, J D Madden, P C MacDonald