American journal of perinatology最新文献

{"title":"Fetal Growth Ultrasound in Obese Patients for the Detection of Growth Abnormalities.","authors":"Juliana G Martins, Elizabeth Miller, Rebecca Horgan, Tetsuya Kawakita","doi":"10.1055/a-2460-5846","DOIUrl":"10.1055/a-2460-5846","url":null,"abstract":"<p><p>This study aimed to examine the impact of maternal obesity on fetal growth abnormalities including fetal growth restriction (FGR) and large for gestational age (LGA) fetuses.Secondary analysis from the Nulliparous Pregnancy Outcomes Study: Monitoring Mothers-to-be (nuMoM2b). The study excluded individuals with pregestational or gestational diabetes, chronic hypertension, and other major maternal medical conditions. First-trimester ultrasound was performed to establish accurate dating criteria. Ultrasound assessments were performed at 16 to 21 and 22 to 29 weeks of gestation. Our exposure was the presence of prepregnancy obesity. Our primary outcome was rates of fetal growth abnormalities identified by ultrasound, defined as FGR (estimated fetal weight [EFW] or abdominal circumference <10th percentile) or LGA (EFW >90th percentile) among obese compared with nonobese women. A secondary analysis was performed after limiting ultrasound performed from 28 to 29 weeks. To estimate adjusted relative risks (aRRs) with 95% confidence intervals (95% CIs), we used generalized linear models with Poisson distribution and log link using robust error variance, adjusting for the predefined covariates.Of 7,354 participants, 1,443 (19.6%) had prepregnancy obesity while 5,911 (80.4%) did not. Prepregnancy obesity compared with normal weight was associated with an increased risk of fetal growth abnormalities both at 16 to 21 weeks (16.0 vs. 13.2%; aRR = 1.23; 95% CI: 1.06-1.42) and 22 to 29 weeks (16.0 vs. 12.1%; aRR = 1.33; 95% CI: 1.14-1.54). Furthermore, prepregnancy obesity compared with normal weight was associated with an increased risk of LGA both at 16 to 21 weeks (12.5 vs. 10.3%; aRR = 1.24; 95% CI: 1.05-1.47) and 22 to 29 weeks (10.6 vs. 6.9%; aRR = 1.66; 95% CI: 1.38-2.01). In a secondary analysis limited to the ultrasound at 28 to 29 weeks, both fetal growth abnormalities and LGA were associated with the presence of obesity. In any of the analyses, prepregnancy obesity was not associated with FGR compared with normal weight.Maternal obesity is associated with an increased risk of fetal growth abnormalities and LGA fetuses. · Obesity is associated with increased LGA risk.. · Association between obesity and FGR remains unclear.. · Ultrasound is effective in obese women to detect fetal growth abnormalities.. · Future research is needed to assess the association between obesity and FGR..</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":"1059-1065"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142575124","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"CircTLK1 Knockdown Alleviates Cell Inflammation and Apoptosis by Regulating Elavl1/Nox4 Axis in Neonatal Sepsis-Induced Lung Injury in Mice.","authors":"Hongxia Li, Jiansheng Li, Jin Zhang","doi":"10.1055/a-2463-4275","DOIUrl":"10.1055/a-2463-4275","url":null,"abstract":"<p><p>Septic acute lung injury (ALI) is a common complication of sepsis with high morbidity and mortality but lacks specific treatment. This study aimed to elucidate the role of circular RNA TLK1 (circTLK1) in neonatal septic ALI.Murine cecal slurry was used to induce neonatal sepsis-induced ALI model in vivo. Hematoxylin and eosin staining was performed to detect the pathological changes in lung tissues. Pulmonary microvascular endothelial cells were treated with lipopolysaccharide (LPS) to induce neonatal sepsis-induced ALI model in vitro. The levels of IL-1β and IL-6 were detected by enzyme-linked immunosorbent assay. A lactate dehydrogenase (LDH) detection kit was used to detect LDH activity. Cell Counting Kit-8 assay and flow cytometry detected cell viability and apoptosis. The genes' expression was measured by quantitative real-time reverse-transcription polymerase chain reaction and western blot. The relationship between circTLK1 and Elavl1 or Elavl1 and Nox4 was detected using RNA immunoprecipitation assay.Our results illustrated that circTLK1 was highly expressed in neonatal sepsis-induced ALI model, and circTLK1 knockdown alleviated cell inflammation and apoptosis in neonatal sepsis-induced ALI model. Similarly, we found that circTLK1 knockdown alleviated neonatal sepsis-induced ALI. Mechanically, circTLK1 mediated Elavl1 binding to Nox4 messenger RNA and increased its stability. Functionally, circTLK1 knockdown alleviated cell inflammation and apoptosis by regulating Nox4 in the neonatal sepsis-induced ALI model.CircTLK1 knockdown alleviated cell inflammation and apoptosis by the Elavl1/Nox4 axis in neonatal sepsis-induced ALI. Our research provided a novel direction for the treatment of neonatal sepsis-induced ALI. · CircTLK1 knockdown relieved neonatal septic ALI.. · CircTLK1 mediated Elavl1 binding to Nox4 mRNA..</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":"1091-1102"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142891398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diabetes and Early Development: Epigenetics, Biological Stress, and Aging.","authors":"Guanglei Wang, Wei-Bin Shen, Anna Wu Chen, E Albert Reece, Peixin Yang","doi":"10.1055/a-2405-1493","DOIUrl":"10.1055/a-2405-1493","url":null,"abstract":"<p><p>Pregestational diabetes, either type 1 or type 2 diabetes, induces structural birth defects including neural tube defects and congenital heart defects in human fetuses. Rodent models of type 1 and type 2 diabetic embryopathy have been established and faithfully mimic human conditions. Hyperglycemia of maternal diabetes triggers oxidative stress in the developing neuroepithelium and the embryonic heart leading to the activation of proapoptotic kinases and excessive cell death. Oxidative stress also activates the unfolded protein response and endoplasmic reticulum stress. Hyperglycemia alters epigenetic landscapes by suppressing histone deacetylation, perturbing microRNA (miRNA) expression, and increasing DNA methylation. At cellular levels, besides the induction of cell apoptosis, hyperglycemia suppresses cell proliferation and induces premature senescence. Stress signaling elicited by maternal diabetes disrupts cellular organelle homeostasis leading to mitochondrial dysfunction, mitochondrial dynamic alteration, and autophagy impairment. Blocking oxidative stress, kinase activation, and cellular senescence ameliorates diabetic embryopathy. Deleting the <i>mir200c</i> gene or restoring <i>mir322 expression</i> abolishes maternal diabetes hyperglycemia-induced senescence and cellular stress, respectively. Both the autophagy activator trehalose and the senomorphic rapamycin can alleviate diabetic embryopathy. Thus, targeting cellular stress, miRNAs, senescence, or restoring autophagy or mitochondrial fusion is a promising approach to prevent poorly controlled maternal diabetes-induced structural birth defects. In this review, we summarize the causal events in diabetic embryopathy and propose preventions for this pathological condition. · Maternal diabetes induces structural birth defects.. · Kinase signaling and cellular organelle stress are critically involved in neural tube defects.. · Maternal diabetes increases DNA methylation and suppresses developmental gene expression.. · Cellular apoptosis and senescence are induced by maternal diabetes in the neuroepithelium.. · microRNAs disrupt mitochondrial fusion leading to congenital heart diseases in diabetic pregnancy..</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":"977-987"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103490","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Posttraumatic Stress Symptoms among Obstetricians with Personal Experience of Birth Trauma.","authors":"Anna R Whelan, Laurie B Griffin, Melissa L Russo, Nina K Ayala, Emily S Miller, Melissa A Clark","doi":"10.1055/a-2452-7862","DOIUrl":"10.1055/a-2452-7862","url":null,"abstract":"<p><p>Psychological birth trauma (BT), defined as an event that occurs during labor and delivery involving actual or threatened harm or death to the pregnant person and/or their baby, has been reported in up to one-third of births. Obstetrician-Gynecologists (OBGYNs) who personally experience BT are at a unique risk of re-traumatization upon return to work. We aimed to investigate the prevalence of personal BT among obstetricians and their perceptions of how personal BT impacts their experience of caring for obstetric patients.We performed a web-based survey of OBGYNs who had given birth. Participants were recruited from the \"OMG (OBGYN Mom Group)\" on Facebook. The questionnaire assessed individuals' personal experience of childbirth using items adapted from the \"City Birth Trauma Scale\" to assess posttraumatic symptoms related to their childbirth and patient interactions following the personal experience of BT. Responses were categorized by whether or not the participant considered one or more of their own births to be traumatic. Posttraumatic stress symptoms (PTSSs) and symptoms of occupational re-traumatization were compared by reported BT. Bivariable analyses were used.Of the 591 OBGYNs who completed the survey, 180 (30.5%) reported experiencing BT. Ninety-two percent of OBs cared for birthing patients after giving birth. There were no differences in demographic or clinical practice characteristics between those with and without BT. OBGYNs with BT experienced PTSSs including flashbacks (60.6 vs. 14.4%), amnesia (36.7 vs. 20.9%), and insomnia (24.4 vs. 1.2%) at higher rates than those without BT (<i>p</i> < 0.001).Almost one-third of OBGYNs in this sample reported personally experiencing BT, mirroring data from reported BT rates in the general population. Given that OBGYNs are at high risk for occupational re-traumatization, initiatives focused on improving support for birthing OBGYNs upon returning to work should be studied to assess the impact on emotional wellness among practicing OBGYNs. · Birthing OBGYNs experience psychological BT at similar rates to the general population.. · OBGYNs who experience personal BT may experience PTSSs at work.. · Further research on the prevalence of personal BT among OBGYNs is needed..</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":"971-976"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142520716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Social Determinants of Health and Diabetes in Pregnancy.","authors":"Christine Field, Xiao-Yu Wang, Maged M Costantine, Mark B Landon, William A Grobman, Kartik K Venkatesh","doi":"10.1055/a-2405-2409","DOIUrl":"10.1055/a-2405-2409","url":null,"abstract":"<p><p>Social determinants of health (SDOH) are the conditions in which people are born, grow, work, live, and age. SDOH are systemic factors that may explain, perpetuate, and exacerbate disparities in health outcomes for different populations and can be measured at both an individual and neighborhood or community level (iSDOH, nSDOH). In pregnancy, increasing evidence shows that adverse iSDOH and/or nSDOH are associated with a greater likelihood that diabetes develops, and that when it develops, there is worse glycemic control and a greater frequency of adverse pregnancy outcomes. Future research should not only continue to examine the relationships between SDOH and adverse pregnancy outcomes with diabetes but should determine whether multilevel interventions that seek to mitigate adverse SDOH result in equitable maternal care and improved patient health outcomes for pregnant individuals living with diabetes. · SDOH are conditions in which people are born, grow, work, live, and age.. · SDOH are systemic factors that may explain, perpetuate, and exacerbate disparities in health outcomes.. · SDOH can be measured at the individual and neighborhood level.. · Adverse SDOH are associated with worse outcomes for pregnant individuals living with diabetes.. · Interventions that mitigate adverse SDOH to improve maternal health equity and outcomes are needed..</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":"988-996"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142103506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Attempted Mode of Delivery on Neonatal Outcomes in Nulliparous Individuals According to Body Mass Index.","authors":"Rula Atwani, George Saade, Tetsuya Kawakita","doi":"10.1055/a-2451-9197","DOIUrl":"10.1055/a-2451-9197","url":null,"abstract":"<p><p>This study aimed to compare neonatal and maternal outcomes based on the attempted mode of delivery, stratified by prepregnancy body mass index (BMI; kg/m²) in nulliparous individuals.This was a repeated cross-sectional analysis of U.S. vital statistics Live Birth and Infant Death-linked data from 2011 to 2020. The analysis was restricted to nulliparas with singleton pregnancies and cephalic presentation who delivered at term. Our primary outcome was a composite neonatal outcome. We also examined a composite maternal outcome. We compared outcomes between individuals who attempted labor and those who opted for nonlabor cesarean delivery, categorized by BMI (<18.5, 18.5-24.9, 25-29.9, 30-39.9, ≥40). To account for significant differences in baseline characteristics between groups, Coarsened Exact Matching was applied using a k-to-k solution. We employed modified Poisson regression and calculated a difference-in-difference (DID) to compare differences in predicted proportions across BMI categories.Out of 9,709,958 individuals, 1,083,332 were included in the matched analysis. Compared with attempted vaginal delivery, nonlabor cesarean delivery was associated with an increased risk of the composite neonatal outcome across all BMI categories. However, the increase in risk was less pronounced in higher BMI categories compared with the reference group (BMI 18.5-24.9). For maternal outcomes, nonlabor cesarean delivery was associated with an increased risk of the composite maternal outcome in the BMI 18.5-24.9 and 25-29.9 categories. In contrast, the risk of adverse maternal outcomes associated with nonlabor cesarean delivery was lower in higher BMI groups compared with the reference group, with DID values ranging from -0.12 in the BMI 30-39.9 group to -0.16 in the BMI ≥40 group.Nonlabor cesarean delivery, as compared with attempted vaginal delivery, was associated with adverse neonatal outcomes across all BMI categories, though the relative increase in risk was diminished in higher BMI groups. · Compared with attempting vaginal delivery, nonlabor cesarean was associated with an increased risk of the composite neonatal outcome in all BMI classes (range of absolute risk difference 1.27-2.35%).. · The increased risk of the composite neonatal outcome was less pronounced in nulliparous individuals with a BMI of 40 kg/m2 or greater.. · Even for individuals with high BMI, attempting vaginal delivery is reasonable..</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":"1003-1011"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142492904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Transplacental Transport Rates of Anti-Pertussis Toxin-IgG and Anti-Filamentous Hemagglutinin-IgG Antibodies in Newborns by Week of Birth.","authors":"Oguzhan Inceli, Cemile Sonmez, Elif Ece İnceli, Hasan Onur Topçu, Mujde Can Ibanoglu, Yaprak Engin-Ustun","doi":"10.1055/a-2457-2721","DOIUrl":"10.1055/a-2457-2721","url":null,"abstract":"<p><p>The aim of this study is to investigate the lack of knowledge about the transplacental transport of antibodies in unvaccinated term and preterm infants and possible differences in antibody-mediated immunity in the fetus depending on maternal vaccination in their own infancy.The study was conducted as a prospective cross-sectional study between 2017 and 2018 and included a total of 334 participants. The study included 194 pregnant women with a preterm birth (before 37 weeks) and 140 pregnant women with a term birth. Both umbilical cord blood and maternal blood were used to measure serum levels of anti-pertussis toxin (PT) immunoglobulin (Ig) G and anti-filamentous hemagglutinin (FHA) IgG.The results showed that anti-FHA IgG antibody levels in the cord blood of women who had delivered at term were significantly higher than those of preterm infants (<i>p</i> = 0.002). The placental transfer rate of anti-PT IgG was higher in women who delivered prematurely, but this difference was not statistically significant (<i>p</i> = 0.128). However, transfer rates for anti-FHA were significantly higher in women who had delivered prematurely (<i>p</i> = 0.001). In addition, transmission rates for both antibodies were found to be significantly lower in women who delivered before 32 weeks gestation than in women who delivered at term (<i>p</i> = 0.006, <i>p</i> < 0.001). Antibody transfer rates were found to be positively correlated with both gestational age and birth weight.In summary, although placental antibody transfer rates increased with gestational age, transfer rates and antibody levels were low in pregnant women, particularly in women who had given birth before 32 weeks gestation. · Transport. · Anti-PT IgG. · Anti-FHA IgG antibodies.</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":"1051-1058"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142754569","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Congenital Colorectal Conditions: Caregiver Perspectives of Their Experience in the Neonatal Intensive Care Unit.","authors":"Vatche Melkonian, Andrea Bischoff, Luis De La Torre, Jill Ketzer, Kristina Matkins, Laura Judd-Glossy","doi":"10.1055/a-2463-4207","DOIUrl":"10.1055/a-2463-4207","url":null,"abstract":"<p><p>This study aimed to examine the experiences of children with colorectal conditions who spent time in the neonatal intensive care unit (NICU) and their caregivers.In March 2024, a 36-question survey was sent to the Colorectal Support Network Facebook community, to gather information from caregivers of children who have a congenital colorectal diagnosis and spent time in the NICU.Fifty-two families completed the survey. Most patients were diagnosed after birth (89.47%). Approximately half of respondents stayed in the NICU for 1 to 2 weeks (50.88%), lived less than 60 minutes away from the hospital (54.91%), and felt somewhat uncomfortable (28.07%) or very uncomfortable (21.05%) caring for their child's medical needs after discharge. Also, 49.12% of caregivers were informed of their child's future bowel control prognosis. When asked for suggestions to improve care in the NICU, common themes included the importance of having colorectal congenital anomalies addressed by colorectal surgeons and the need for families to be informed about support groups.Counseling families in the NICU with congenital colorectal conditions can be improved by providing additional information and support for families prior to discharge, informing them about their child's prognosis for bowel control and connecting them with other families. · Patients with colorectal conditions should be informed of pediatric colorectal surgeon specialists.. · Families benefit from the knowledge of available support groups regarding their children's condition.. · There are many areas in the care of NICU patients with colorectal diseases, which can be improved..</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":"1083-1090"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142602580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Survey of Minimally Invasive Surfactant Use in the United States.","authors":"Natasha Ahn, Matthew Derrick, Walid Hussain","doi":"10.1055/a-2453-6883","DOIUrl":"10.1055/a-2453-6883","url":null,"abstract":"<p><p>Minimally invasive surfactant therapy (MIST) has become the standard of care in delivering surfactant noninvasively in many parts of the world, particularly throughout Europe; however, centers in the United States have been slower to adopt it. The most recent assessment of the use of MIST in the United States was in 2018 by Kurepa et al. Considering the increasing evidence favoring MIST, this paper reassessed the current rate of utilization and aims to examine barriers to MIST implementation.A web-based survey was distributed to approximately 4,500 individuals in the American Academy of Pediatrics Section of Neonatal-Perinatal Medicine (AAP SoNPM) mailing list. The questions were aimed at addressing MIST usage in the United States, examining barriers for neonatology providers to implement MIST into their practice, and determining the use of sedation during the MIST procedure.Of the 381 respondents, 39% used MIST as part of their practice, which was an increase from 15% in 2018. The most prevalent barrier to implementation was the lack of procedural training. There was a large increase in the use of sedation for the procedure compared with 2018.MIST use among AAP SoNPM respondents has more than doubled since 2018; InSurE (INtubation-SURfactant delivery Extubation) remains the most prevalent method of surfactant delivery in non-intubated patients. The list of different types of barriers and comments provided by respondents can be a resource for units planning to implement MIST. · The usage of MIST in the United States.. · What are the barriers to MIST implementation?. · The usage of sedation during MIST procedure..</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":"1043-1050"},"PeriodicalIF":1.5,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142715034","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Parents and Health Care Providers' Perspectives on Vital Signs Monitoring Technologies in the Neonatal Intensive Care Unit: An International Survey.","authors":"Eva Senechal, Daniel Radeschi, Robert Kearney, Wissam Shalish, Guilherme Sant'Anna","doi":"10.1055/a-2604-8329","DOIUrl":"https://doi.org/10.1055/a-2604-8329","url":null,"abstract":"<p><p>This study aimed to assess the views of parents and neonatal intensive care unit (NICU) health care providers (HCPs) on current wired vital signs monitoring and future wireless alternatives.Prospective cross-sectional survey was conducted between March and July 2023, targeting three groups: (1) NICU parents, (2) physicians, and (3) nurses and respiratory therapists (RT) and physiotherapists (PT). A 17-question survey was developed to assess several perspectives with current vital signs monitoring and a possible wireless monitoring system. NICU parents completed paper surveys and HCPs participated via an anonymous electronic survey. The original English survey was tailored for different respondent groups, translated into French, Spanish, and Portuguese, and distributed through neonatal research networks. Responses from each group were analyzed as totals (%), with within-group comparisons assessed using the Wilcoxon signed-rank test. Additionally, between-group comparisons were conducted using the chi-square test of independence or Fisher's exact test, as appropriate.A total of 1,141 responses were included (25 parents, 438 physicians, and 678 nurses, RTs, and PTs). Only 52% of parents were satisfied with current wired systems; 68% reported wires hindered infant handling, and 52% cited interference with skin-to-skin care. Both physicians and HCPs expressed low satisfaction with the current system. Common concerns included tangling, skin irritation, and workload. Support for wireless technology introduction was high across all groups (parents = 60%, physicians = 91%, and nurses, RTs, and PTs = 87%), with main perceived benefits including improved kangaroo mother care (KMC), reduced patient discomfort, and enhanced bonding. All groups expressed accuracy, safety, battery life, and cost concerns of a possible wireless system.Parents and HCPs are generally dissatisfied with the current NICU vital signs monitoring systems, primarily due to concerns with wires and cables and interference with KMC. Wireless technologies were mostly supported, but data on reliability, safety, and economic feasibility will be critical for development and successful implementation. · Parents and HCPs dislike wired systems due to tangling, skin irritation, and interference with care.. · Support for wireless monitoring was viewed positively by parents and very positively by HCP.. · Wireless systems were seen as beneficial for KC, reducing patient discomfort, and improving bonding.. · However, each group expressed concerns about a potential future wireless monitoring system.. · Accuracy, battery life, radiation, and cost must be addressed before wireless systems can be adopted..</p>","PeriodicalId":7584,"journal":{"name":"American journal of perinatology","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-05-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180589","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}