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European journal of toxicology and environmental hygiene. Journal europeen de toxicologie最新文献

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Toxicological studies of photosensitizer agents and photodegradable polyolefins. 光敏剂和光可降解聚烯烃的毒理学研究。
European journal of toxicology and environmental hygiene. Journal europeen de toxicologie Pub Date : 1976-03-01
L Caprino, G Togna, M Mazzei
{"title":"Toxicological studies of photosensitizer agents and photodegradable polyolefins.","authors":"L Caprino,&nbsp;G Togna,&nbsp;M Mazzei","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors report the results of a series of toxicological tests conducted on plastic materials (polyethylene) activated with tetraphenylbutadiene (TPB) an additive recently proposed as a sensitizer capable of photodegrading plastic materials. The toxic effects of polyethylene, TPB, and TPB's degradation products were investigated in rabbits, mice and rats. The studies revealed these products to possess a very low toxicity.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 2","pages":"99-103"},"PeriodicalIF":0.0,"publicationDate":"1976-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12453180","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Determination of lead by atomic absorption spectrophotometry with regard to toxicology research]. [毒理学研究用原子吸收分光光度法测定铅]。
European journal of toxicology and environmental hygiene. Journal europeen de toxicologie Pub Date : 1976-03-01
N Oudart, C Guichard, C Delage
{"title":"[Determination of lead by atomic absorption spectrophotometry with regard to toxicology research].","authors":"N Oudart,&nbsp;C Guichard,&nbsp;C Delage","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The toxicity of lead in the human environment is acquiring a growing interest which lead us to choose a quick, precise, sensitive and specific method able to perform number of measurements. Thanks to the survey consisting in a dosage of lead by atomic-absorption spectrometric, we are able to confirm the advantages and superiority of such a method and to employ it for the toxicologic research of lead in food, water, industrial atmosphere, and biological liquids.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 2","pages":"69-73"},"PeriodicalIF":0.0,"publicationDate":"1976-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12453220","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Toxic effects of methoxy-ethyl-mercury in the quail: influence of fasting]. [甲氧基乙基汞对鹌鹑的毒性作用:禁食的影响]。
European journal of toxicology and environmental hygiene. Journal europeen de toxicologie Pub Date : 1976-03-01
J C Godfrain, A G Rico, V Burgat-Sacaze, J P Braun, P Benard
{"title":"[Toxic effects of methoxy-ethyl-mercury in the quail: influence of fasting].","authors":"J C Godfrain,&nbsp;A G Rico,&nbsp;V Burgat-Sacaze,&nbsp;J P Braun,&nbsp;P Benard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Quails fed methoxy-ethyl-mercury-treated wheat (20 ppm of Hg) during 10 or 20 days, have been submitted to a three-day fasting following contamination. The test proved to be lethal for a number of intoxicated animals but not for controls. Mercury clearance was modified by anorexia; following fasting, there was a redistribution of the metal, with high concentrations in the liver and kidneys. According to the results of a blood survey uric acid, urea and T. G. O. levels appeared to be the most altered parameters. Transient high blood uric acid levels in intoxicated and anorectic animals could be attributed to kidney dysfunctioning. A possible effect of methoxy-ethyl-mercury on neoglycogenesis was discussed.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 2","pages":"79-98"},"PeriodicalIF":0.0,"publicationDate":"1976-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12453222","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Analysis of volatile N-nitrosamines. A brief review]. 挥发性n -亚硝胺分析。[简短回顾]。
European journal of toxicology and environmental hygiene. Journal europeen de toxicologie Pub Date : 1976-01-01
N P Lich, R Truhaut
{"title":"[Analysis of volatile N-nitrosamines. A brief review].","authors":"N P Lich,&nbsp;R Truhaut","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The different steps of analysis of volatile N-Nitrosamines: separation from product, clean up, detection, quantification and confirmation are reviewed and discussed. The two best analysis procedures are: 1) combined gas-chromatography; mass-spectrometry, 2) combined gas-chromatography; thermal energy analyzer. However a bundle of proofs is always necessary to ascertain the presence of Nitrosamines.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 7 Suppl","pages":"408-12"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11988000","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Results of 8 years' research on the toxicologic evaluation of animal food additives by the so-called relay toxicity method]. 【用“接力毒性法”对动物性食品添加剂进行8年毒理学评价的研究结果】。
European journal of toxicology and environmental hygiene. Journal europeen de toxicologie Pub Date : 1976-01-01
R Truhaut, R Ferrando
{"title":"[Results of 8 years' research on the toxicologic evaluation of animal food additives by the so-called relay toxicity method].","authors":"R Truhaut,&nbsp;R Ferrando","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors report the underlying principles of the new methodological approach called \"relay toxicity\" which they proposed eight years ago for the toxicological evaluation of animal feed additives. They stress its value either as a possible criterion of rejection or as a criterion of acceptability. In the latter case, the limiting factor is the difficulty of applying an adequate safety factor when food products destined for human consumption and obtained from animals receiving the additives to be evaluated are administered to laboratory animals. Amongst the examples of the additives which have been subjected to toxicological evaluation using the authors' new method, the following are examined: as growth factor, carbadox, anabolising agents and, in particular, diethylstilboestrol, and steroids used as egglaying potentializers. The results obtained are discussed.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 7 Suppl","pages":"413-22"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12211211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Bromide vegetating skin diseases after treatment by a bromocalcic specialty]. [溴钙专业治疗后的溴化植物性皮肤病]。
European journal of toxicology and environmental hygiene. Journal europeen de toxicologie Pub Date : 1976-01-01
J Arditti, J Follana, J J Bonerandi, J Jouglard
{"title":"[Bromide vegetating skin diseases after treatment by a bromocalcic specialty].","authors":"J Arditti,&nbsp;J Follana,&nbsp;J J Bonerandi,&nbsp;J Jouglard","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors report on a case of vegetating bromoderma observed after therapy with bromocalcic speciality (Calcibronat). Repeated bromine determinations in body fluids enabled, while reconsidering the metabolism of this halogen, to monitor its elimination.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 1","pages":"59-63"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12429731","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Fuorometric analysis of delta-9-tetrahydrocannabinol and its metabolites in urine]. [尿中δ -9-四氢大麻酚及其代谢物的荧光分析]。
European journal of toxicology and environmental hygiene. Journal europeen de toxicologie Pub Date : 1976-01-01
R Bourdon
{"title":"[Fuorometric analysis of delta-9-tetrahydrocannabinol and its metabolites in urine].","authors":"R Bourdon","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The high number of drug addicts using marijuana (Cannabis sativa var. indica) under various forms has lead research workers to propound many a method for the characterization and assaying of delta9-tetrahydrocannabinol (delta9-THC) and its metabolites in biological fluids. Some of them are based on labelled materials, radioimmuno-chemistry, gas chromatography alone or combined with mass spectrometry. No mention of a purely chemical method has been found in the literature, with the exception of characterizations using thin-layer chromatography and formation of dansylated derivatives (5 to 9, 11 to 14, 16, 17, 18, 22, 23, 26, 31, 32, 34, to 38, 43 to 48, 59).</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 1","pages":"11-21"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12429729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Binding of delta-8-THC to human serum proteins: binding as a function of lipoprotein composition]. [δ -8- thc与人血清蛋白的结合:结合与脂蛋白组成的关系]。
European journal of toxicology and environmental hygiene. Journal europeen de toxicologie Pub Date : 1976-01-01
N Capelle, I Treich, M Ayrault-Jarrier, H Hoellinger, J M Scherrmann
{"title":"[Binding of delta-8-THC to human serum proteins: binding as a function of lipoprotein composition].","authors":"N Capelle,&nbsp;I Treich,&nbsp;M Ayrault-Jarrier,&nbsp;H Hoellinger,&nbsp;J M Scherrmann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In accordance with the function of the human lipoprotein composition, using serum of different lipid profiles, the distribution of delta8tetrahydrocannabinol, as isomer of delta9THC, was studied through the use of ultracentrifugation and fraction isolation, followed by biochemical analysis of the VLDL, LDL, and HDL fractions, as well as that of the non-lipoprotein protein fraction. The results indicate the existence of a linear correlation between the distribution of delta8THC and the phospholipids of the lipoprotein cenapse. No correlation between the quantity of bound delta8THC and the other lipoprotein constituents cholesterol, triglycerides, total lipids or protein could be observed.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 1","pages":"5-9"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11392964","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Toxicologic and pharmacologic study of tributyltin oxide (TBTO)]. [三丁基氧化锡(TBTO)的毒理学和药理学研究]。
European journal of toxicology and environmental hygiene. Journal europeen de toxicologie Pub Date : 1976-01-01
R Truhaut, Y Chauvel, J P Anger, N Phu Lick, J van den Driessche, L R Guesnier
{"title":"[Toxicologic and pharmacologic study of tributyltin oxide (TBTO)].","authors":"R Truhaut,&nbsp;Y Chauvel,&nbsp;J P Anger,&nbsp;N Phu Lick,&nbsp;J van den Driessche,&nbsp;L R Guesnier","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Toxicological study on bis-(tributyl-tin) oxyde shows a delayed toxicity of this compound in acute experiments. The same result is obtained in sub-chronic study. Most of the animals die after a great loss of weight. In pharmacological study, T. B. T. O. depresses central nervous system, but his action on ortho and parasympathetic system is slight and non specific. In rat, rabbit and dog, the effect is a fall in blood pressure that result from a depression of the vascular smooth muscle. The death of the animal is due to respiratory arrest by a central mechanism.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 1","pages":"31-40"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11393858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Effect of subacute fluorine poisoning in the rabbit on fluorine and phosphorus-calcium metabolism and on radiography of the skeleton]. [亚急性氟中毒对家兔氟、磷钙代谢及骨骼影像学的影响]。
European journal of toxicology and environmental hygiene. Journal europeen de toxicologie Pub Date : 1976-01-01
J Elsair, J Poey, M Reggabi, F Hattab, N Benouniche, C Spinner
{"title":"[Effect of subacute fluorine poisoning in the rabbit on fluorine and phosphorus-calcium metabolism and on radiography of the skeleton].","authors":"J Elsair,&nbsp;J Poey,&nbsp;M Reggabi,&nbsp;F Hattab,&nbsp;N Benouniche,&nbsp;C Spinner","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Rabbit subacute fluoride intoxication effects (21,4 mg a day for 10 months) are researched on fluor, calcium and phosphorus metabolism and on skeletal radiology. Fluoremy increase (p less than 0.05) and there is a strong fluor retention (p less than 0.01), due to fluor digestive utilization coefficient increase (p less than 0.05), in spite of relative hyperfluorury (p less than 0.05). Calcemy decreases (p less than 0.01), but phosphatemy and alkaline phosphatasemy do not vary but a little. Calcium and phosphorus balances become negative (p less than 0.05), due to calcium digestive utilization coefficient inversion (p less than 0.05) and phosphorus digestive utilization coefficient decrease (p less than 0.05) and hypercalciury (p less than 0.05) and hyperphosphatury (p less than 0.05) with phosphorus renal reabsorption coefficient decrease (p less than 0.05). Some skeletal radiological abnormalities appear on rachis and limbs.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 7 Suppl","pages":"429-37"},"PeriodicalIF":0.0,"publicationDate":"1976-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12211213","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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