{"title":"[Evoluation of biologic balance as a function of radiologic status in a population living in a endemic fluoride zone of southern Algeria].","authors":"J Poey, J Elsair, P Morgan, M Reggabi, F Hataab","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Chronic fluoride intoxication in subjects living in an endemic South Algerian zone: El Oued (drinking water fluor: 3 to 5 mg/l), provokes some blood and urinary levels modifications, when compared to normals living in Algiers (drinking water fluor: 0,6 mg/l). These modifications are the more often present in stade 0 (normal radiologic aspect) and do not increase with radiological evolution (stades I, II, III). Fluoremy and fluorury increase. Phosphocalcic metabolism is altered. Tubular reabsorption coefficient, particularly, decreases strongly. Using renal functional exploration, a pretty soon tubular failure is founded, which preceeds glomerular failure. Blood levels of certain products and enzymes are studied.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 3","pages":"179-86"},"PeriodicalIF":0.0,"publicationDate":"1976-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12137660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Irritant power of the principle chlorinated aliphatic solvents on the skin and ocular mucosa of the rabbit].","authors":"P Duprat, L Delsaut, D Gradiski","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A study was carried out in the rabbit in order to compare the cutaneous and ocular mucosa irritant powers of the principal aliphatic chloride solvents and of pure hexachlorobutadiene. Using Draize's method, that of the official technique for the assessment of cosmetic products and the interpretation of Kay and Calandra, a study was made of the effects of a single application or instillation of the common aliphatic chloride solvents. Macroscopic observations were followed by histological examination of the lesions and their course. With the exception of trichloro trifluoro-1,2,3-ethane, these substances are primary irritants but their effects on rabbit skin and ocular mucosa differ.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 3","pages":"171-7"},"PeriodicalIF":0.0,"publicationDate":"1976-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12137662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Role of the laboratory in the diagnosis and treatment of lead poisoning].","authors":"F Buneaux, P Protin, M Besson-leaud, P Fabiani","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A case of therapeutic lead poisoning in a six-week old child is reported, this aetiology being very common in paediatrics. The role of the laboratory in treatment is described, the latter having involved the addition of disodium calcitetracemate to the peritoneal dialysis fluid.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 3","pages":"165-70"},"PeriodicalIF":0.0,"publicationDate":"1976-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12137665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Analysis of digoxin by a radio-immunologic].","authors":"J M Scherrmann, R Bourdon","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A more accurate knowledge of the effects of cardiotonic heterosides can be gained using radiocompetition. The present investigation aimed at: -comparing two commercial kits, the usual quality criteria being applied; -estimating cross-reaction between the immune systems and the endogenous as well as exogenous structural analogues; -establishing the therapeutical or toxic levels in man.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 3","pages":"133-54"},"PeriodicalIF":0.0,"publicationDate":"1976-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12137791","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Poisoning by anorexigenics. Information from the data bank of the Anti-Poison Center of Marseille (1973)].","authors":"J Jouglard, A Brun, A Botta","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Using the data bank developed by the Computer Service of the Lyon Hospitals, the Anti-Poisons Centre of Marseille presents an initial study of intoxications by appetite suppressants. The work was complemented by a simultaneous study using conventional manual techniques. An epidemiologic review of 1973 and an approximate assessment of toxic doses in the adult and child were possible. They should be of particular use in answering telephone enquiries at anti-poison centres.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 3","pages":"197-90"},"PeriodicalIF":0.0,"publicationDate":"1976-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12137663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Determination of acetylator phenotype of isoniazid by superimposed sinusodial tension polarography].","authors":"J J Vallon, A Badinand, C Bichon","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Alternative current polarography has been applied to specific determination of INH and acetyl-isoniazide in serum and urine. Determinations can be achieved directly on diluted urines. The method allows measure of pharmacocinetic parameters and determination of acetylation phenotype following I.V. administration of the drug.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 3","pages":"155-64"},"PeriodicalIF":0.0,"publicationDate":"1976-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12137792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Toxicity and bioaccumulation of isomers of polychlorobiphenyls by the ciliated protozoan Colpidium campylum (Stokes)].","authors":"D Dive, F Erb, H Leclerc","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A toxicity and bioaccumulation study was carried out in Colpidium campylum with sixteen pure isomers of mono-, di-, tri-, tetra-, penta-, hexa- and heptachlorobiphenyls and a commercial product: Pyralene 3010, dissolved in alcohol, after factorial study of the summation of effects between PCB and solvent. The position of chlorine atoms on the aromatic rings and their number influence toxicity, probably in relationship to the possibilities of hydroxylation of these molecules. The experimental conditions must be very carefully respected to obtain reproducible results.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 2","pages":"105-11"},"PeriodicalIF":0.0,"publicationDate":"1976-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12007750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J P Anger, F Anger, Y Chauvel, R L Girre, N Curtes, J P Curtes
{"title":"[Fatal poisoning by water dropwort (Oenanthe crocata)].","authors":"J P Anger, F Anger, Y Chauvel, R L Girre, N Curtes, J P Curtes","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors relate clinical and toxicological data concerning a recent deadly intoxication by OEnanthe crocata absorption and stress upon awkwardness of clinical diagnosis. Most frequent cases were observed by veterinarians in bovine and porcine intoxications. This plant grows in wet meadows of western France and south-west of England. In spite of its rarity, this intoxication is mostly dangerous and oftenest lethal.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 2","pages":"119-25"},"PeriodicalIF":0.0,"publicationDate":"1976-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12128886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A Heyndrickx, C Van Peteghem, M Van Den Heede, R Lauwaert
{"title":"A double fatality with children due to fumigated wheat.","authors":"A Heyndrickx, C Van Peteghem, M Van Den Heede, R Lauwaert","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Two children, four and two years old, played on top of wheat, that had been fumigated with malathion, pyrethrum and phosphine. Both died within 18 hours. Because after the autopsy, death could not be attributed to any organic or violent cause, a toxicological analysis was carried out. No drugs, except alcohol, was detected. Those results were attributed to hydrolysis of malathion, yielding two molecules of ethanol. As this was an indirect proof of malathion ingestion, it was assumed that phosphine had been ingested as well and that consequently this was the cause of death, because it is much more toxic than malathion and because it was continuously generated from not completely dissolved aluminiumphosphide tablets, while the children were still playing.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 2","pages":"113-8"},"PeriodicalIF":0.0,"publicationDate":"1976-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12453218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Detection and quantitative estimation of morphine in the urine of drug addicts by combined 2-dimensional thin-layer chromatography and spectrofluorometry].","authors":"A Viala, M Estadieu","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Following extraction from urine and thin-layer bidimensional chromatography, the suspected spot of morphine is located by UV examination at 350 nm and eluted with methanol by means of \"Eluchrom\" apparatus. The dried residue is then subjected to spectrofluorimetric analysis, in definite conditions. This procedure can be used to confirm the identification of the alkaloid and to achieve its estimation. The sensitivity and the recoveries of various quantities of morphine added to urine were determined.</p>","PeriodicalId":75837,"journal":{"name":"European journal of toxicology and environmental hygiene. Journal europeen de toxicologie","volume":"9 2","pages":"75-8"},"PeriodicalIF":0.0,"publicationDate":"1976-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11230411","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}