CRC critical reviews in microbiology最新文献

Viruses in soil systems. 土壤系统中的病毒。

CRC critical reviews in microbiology Pub Date : 1979-11-01 DOI: 10.3109/10408417909082016

S M Duboise, B E Moore, C A Sorber, B P Sagik

引用次数: 40

Herpes simplex virus-host cell interactions. 单纯疱疹病毒与宿主细胞的相互作用。

CRC critical reviews in microbiology Pub Date : 1979-11-01 DOI: 10.3109/10408417909082015

L S Kucera

引用次数: 3

Volatile substances from actinomycetes: their role in the odor pollution of water. 放线菌挥发性物质:它们在水的气味污染中的作用。

CRC critical reviews in microbiology Pub Date : 1979-11-01 DOI: 10.3109/10408417909082014

N N Gerber

引用次数: 142

Haemophilus influenzae: immunology and immunoprotection. 流感嗜血杆菌:免疫学和免疫保护。

CRC critical reviews in microbiology Pub Date : 1978-09-01 DOI: 10.3109/10408417809090618

M Solotorovsky, M Lynn

引用次数: 21

Behavior and the excitable membrane in Paramecium. 草履虫的行为和可兴奋膜。

CRC critical reviews in microbiology Pub Date : 1978-09-01 DOI: 10.3109/10408417809090620

B J Byrne, B C Byrne

引用次数: 24

Experimental evolution in bacteria. 细菌的实验进化。

CRC critical reviews in microbiology Pub Date : 1978-09-01 DOI: 10.3109/10408417809090619

T T Wu

引用次数: 19

Recent advances in polyoma virus research. 多瘤病毒研究的最新进展。

CRC critical reviews in microbiology Pub Date : 1978-01-01 DOI: 10.3109/10408417809090624

R A Consigli, M S Center

引用次数: 5

The characterization and functional significance of plasma membrane Fc Receptors. 质膜Fc受体的表征及其功能意义。

CRC critical reviews in microbiology Pub Date : 1978-01-01 DOI: 10.3109/10408417909101176

S H Zuckerman, S D Douglas

{"title":"The characterization and functional significance of plasma membrane Fc Receptors.","authors":"S H Zuckerman, S D Douglas","doi":"10.3109/10408417909101176","DOIUrl":"https://doi.org/10.3109/10408417909101176","url":null,"abstract":"The importance of various components of the plasma membrane in the generation of the immune response has long been recognized. The identification and characterization of functional membrane receptors are essential for an understanding of the molecular basis of the immune response. The Fc receptor can be operationally defined as a site on the plasma membrane which is capable of binding the Fc portion of IgG. The Fc receptor has been reported on both lymphoid and nonlymphoid cell types. The functional significance of the receptor on these cell populations, as well as the biochemistry of the receptor, is not well established and is currently an important area of investigation. In this review, the Fc receptor will be discussed, primarily in human and murine lymphoid and macrophage cell populations, as a model of membrane immunoreceptors. The review will be divided into four sections. In the first section, consideration will be given to the binding assays used to study Fc receptor-ligand interactions and the class and subclass specificity of the receptor. The possibility of receptor-receptor interaction and quantitation of receptor sites will be discussed. The second phase of the review will be concerned with the fractionation and biochemistry of this receptor system, emphasizing the differences reported in receptor composition from different cell sources. In the third section of the review, the biologic significance of the receptor will be examined. The importance of the Fc receptor in opsonization and phagocytosis by mononuclear phagogytes, B-cell activation, antibody-dependent cell cytotoxicity, and the possible relationship of Fc receptors to the histocompatibility-linked immune response genes will be discussed. Finally, in the fourth section, the possible mechanisms of receptor regulation will be considered. Cell fusion experiments which have been performed and the expression of receptor activity on the hybrid cell clones will be discussed. Receptor regulation at the physiologic level will include the effects of cyclic nucleotide levels and cell cycle on receptor expression. It is the intent of this review to provide a detailed analysis of the Fc receptor and to emphasize its importance in microbiology, cell biology, and immunology.","PeriodicalId":75751,"journal":{"name":"CRC critical reviews in microbiology","volume":"7 1","pages":"1-26"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10408417909101176","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11590921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 35

Cellular antimicrobial immunity. 细胞抗微生物免疫。

CRC critical reviews in microbiology Pub Date : 1978-01-01 DOI: 10.3109/10408417909101177

F M Collins

{"title":"Cellular antimicrobial immunity.","authors":"F M Collins","doi":"10.3109/10408417909101177","DOIUrl":"https://doi.org/10.3109/10408417909101177","url":null,"abstract":"Acquired resistance to infectious disease may be expressed by a predominantly humoral or a cellular mechanism or, more frequently, by a combination of the two. The cellular interactions which are responsible for the induction of the immune response in the skin, lung, intestinal mucosa, genitourinary tract, conjunctiva, and peritoneal cavity are discussed and the role of living or dead vaccines in the induction of acquired resistance is outlined. The host response involves three different cell types: the phagocytic cell (polymorphs or macrophages), the thymus-dependent (T) lymphocyte, and the thymus-independent (B) lymphocyte-plasma cell line. The normal unstimulated phagocytic cell is capable of killing most nonpathogenic bacteria that gain entry to the tissues. However, the presence of opsonic antibodies and activated macrophages is required to eliminate the pathogenic intracellular parasites. Such immunological activation involves the presence of sensitized T-lymphocytes in the lesion. The cellular response is also characterized by the simultaneous development of a state of delayed-type hypersensitivity (DTH), along with the antimicrobial CMI response. A rising humoral response normally develops subsequently. Killed bacterial cells (except when incorporated into Freund's complete adjuvant) induce the humoral response without the CMI reaction so that such vaccines are not able to fully protect the host against the naturally acquired disease. With the development of cell fractionation methods as well as the identification of distinctive cell surface markers, suspensions of B- and T-cells and macrophages can now be prepared for use in increasingly sophisticated transfer and reconstitution studies. The role of the different cell types in the expression of humoral and cellular immunity has been determined, and the effect of various immunopotentiating and immunosuppressive regimens on the immune system as a whole has been evaluated quantitatively. These studies have led to an appreciation of the role played by suppressor B- and T-cells in the interplay of both humoral and cellular components of the host defense system during the development of immune tolerance, desensitization, anergy, autoimmunity, and the expression of an anamnestic immune response following reinfection.","PeriodicalId":75751,"journal":{"name":"CRC critical reviews in microbiology","volume":"7 1","pages":"27-91"},"PeriodicalIF":0.0,"publicationDate":"1978-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.3109/10408417909101177","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"11590922","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 80

Metabolism of sterols in yeast. 酵母中固醇的代谢。

CRC critical reviews in microbiology Pub Date : 1978-01-01 DOI: 10.3109/10408417809090625

L W Parks

引用次数: 189