American journal of obstetrics and gynecology最新文献

{"title":"Experimental evidence that cervical cerclage prevents ascending intra-amniotic infection","authors":"Samuel Parry MD","doi":"10.1016/j.ajog.2025.04.009","DOIUrl":"10.1016/j.ajog.2025.04.009","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"233 1","pages":"Pages 1-3"},"PeriodicalIF":8.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143921005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal exposure to vaginal progesterone for the prevention of preterm birth is not associated with abnormal psychopathological and cognitive profiles in dichorionic twins at 6 to 9 years of age: a follow-up study of a randomized controlled trial.","authors":"Alfredo Perales,Joan Aviño,Alba Diaz-Martinez,Agustin Conde-Agudelo,Roberto Romero,Luis Rojo,Vicente Serra","doi":"10.1016/j.ajog.2025.04.056","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.04.056","url":null,"abstract":"BACKGROUNDCurrent evidence indicates that administration of vaginal progesterone to women with a twin gestation and a short cervix reduces the risk of preterm birth occurring at early gestational ages and of neonatal morbidity and mortality. However, the potential long-term effects of prenatal administration of vaginal progesterone for preventing preterm birth on the psychopathological and cognitive profiles of twins remain unknown.OBJECTIVETo evaluate the psychopathological and cognitive profiles at 6 to 9 years of age of surviving children born to mothers who participated in a randomized controlled trial that compared two different daily doses of vaginal progesterone (200 mg and 400 mg) to placebo to prevent preterm birth in dichorionic twin gestations.STUDY DESIGNThis is a follow-up study from a multicenter, double-blind, randomized controlled trial with three parallel groups (placebo, vaginal progesterone 200 mg/day, and vaginal progesterone 400 mg/day administered from 20 to 34 weeks of gestation or delivery, whichever came first; randomization ratio 1:1:1). The Child Behavior Checklist for ages 6 to 18 questionnaire and the Raven's Colored Progressive Matrices test of non-verbal intelligence were applied to the participating mothers and their surviving children aged 6 to 9 years, respectively. The participant mothers, questionnaire collector, and database organizer were blinded to the intervention received in the original trial. The primary outcomes were behavioral, emotional, and social problems evaluated by the Child Behavior Checklist for ages 6 to 18 -18 questionnaire, and the intelligence coefficient percentile evaluated by the Raven's Colored Progressive Matrices test. Analyses were performed on an intention-to-treat basis using descriptive and analytical tests. P values <0.05 were considered statistically significant.RESULTSA total of 206 children born to 104 mothers (35.4% of those included in the original randomized controlled trial) were included in the study: 75 were exposed to vaginal progesterone 200 mg/d, 63 to vaginal progesterone 400 mg/d, and 68 to placebo. Overall, there were no significant differences in maternal sociodemographic, pregnancy and neonatal characteristics between participants and non-participants in the follow-up study, as well as between the three participating study groups. The mean scores of the 11 psychopathological syndrome scales evaluated by the Child Behavior Checklist for ages 6 to 18 questionnaire among children exposed to vaginal progesterone 200 mg/d, 400 mg/d or 200 & 400 mg/d were not significantly different to those among children exposed to placebo. There were no significant differences in the mean total Child Behavior Checklist score between the vaginal progesterone groups (31.08 ± 22.58 for the 200 mg/d group, 37.48 ± 28.59 for the 400 mg/d group, and 34.00 ± 25.60 for the 200 & 400 mg/d group) and the placebo group (34.60 ± 25.55) (P=0.38, 0.54, and 0.87, respectively). The mean percentile","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"15 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143926383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of placenta accreta spectrum and vasa previa.","authors":"Yadira L Bribiesca Leon,Shinya Matsuzaki,Zaira N Chavez Jimenez,Fay F Pon,Emi J Komatsu,Jennifer A Yao,Rachel S Mandelbaum,Brian J Gordon,Joseph G Ouzounian,Koji Matsuo","doi":"10.1016/j.ajog.2025.04.068","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.04.068","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"75 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143920996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Frequency and timing of complications within the first postpartum year in the United States and Canada: A systematic review and meta-analysis.","authors":"Janny Xue Chen Ke,Katherine Bilan,Marianne Vidler,Mike Wong,Anthony Chau,Qian Zhang,Jeffrey N Bone,Andrea Enriquez,Ria Sandhu,Ronald B George,Rebecca A Baron,Ammar M Lakda,Justine Dol,Lindsay Blake,Brendan Carvalho,Ronald S Gibbs,Micaela Coombs,Sonia Sekhon,Ernest Tang,Pervez Sultan","doi":"10.1016/j.ajog.2025.04.060","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.04.060","url":null,"abstract":"OBJECTIVEUnderstanding the rates and timing of postpartum complications can facilitate timely screening and management to reduce preventable morbidity and mortality. The aim of this study was to summarize the frequency (prevalence or incidence) and timing of complications from hospital delivery to one year postpartum in the United States and Canada.DATA SOURCESPubMed MEDLINE, Web of Science, EBSCO CINAHL, and the Cochrane CENTRAL and Database of Systematic Reviews were reviewed from January 1, 2010, until December 31, 2024.STUDY ELIGIBILITY CRITERIAInclusion criteria were studies written in English reporting the frequency and timing of medical, procedural/surgical, and psychosocial complications in adults in the United States and Canada, from hospital delivery to 1 year postpartum. Studies with less than 100 patients, not reporting the timing of evaluation, or only included patients with a specific medical condition (e.g. preeclampsia) were excluded.STUDY APPRAISAL AND SYNTHESIS METHODSData screening, extraction, and appraisal were performed by two reviewers. The appraisal tool was the Joanna Briggs Institute instrument for studies reporting prevalence data. Meta-analysis using random effects modelling was performed if a complication was reported in two or more studies.RESULTSOut of 4874 retrieved articles, 117 were included (93 original investigations, 24 reviews). The total sample size from original investigation studies was 246,521,464 patients (median (interquartile range) 6,030 (513 to 327,066) per study). In total, 41 complications and mortality data were extracted, with significant heterogeneity amongst definitions and time points of measurements. The one-year postpartum frequency estimates from meta-analysis (per 10,000, with 95% confidence interval) were anxiety 1,380 (845 - 2,174), depression 1008 (749 - 1,343), hypertension 890 (345 - 2,109), obsessive compulsive disorder 996 (134 - 4,089), hemorrhage 591 (454 - 763), post-traumatic stress disorder 464 (188 - 1,100), surgical infection 581 (12 - 7,678), postpartum severe maternal morbidity 100 (38 - 260), venous thromboembolism 17 (13 - 24), sepsis 11 (8 - 15), cardiomyopathy 1.9 (0.5 - 6.8), severe sepsis 1.2 (0.2 - 9.0), cardiac arrest 0.9 (0.2 to 1.0), acute myocardial infarction 0.25 (0.06 - 1.03), and mortality 1.2 (0.3 - 5.6).CONCLUSIONSWe report frequencies and timings for 41 complications and mortality from delivery to one year postpartum. Of the nine complications that underwent meta-analysis, anxiety, depression, hypertension and hemorrhage were reported most frequently. These results can inform evidence-based resource allocation and guide optimal postpartum monitoring and care pathway development.","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"3 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143921004","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prenatal diagnosis of subamniotic placental cysts.","authors":"Nareenun Chansriniyom,Roberto Romero,Puntabut Warintaksa,Arun Meyyazhagan,Patama Promsonthi,Arunee Singhsnaeh,Piya Chaemsaithong","doi":"10.1016/j.ajog.2025.04.070","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.04.070","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"25 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143921006","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Reproductive Access: The Influence of Expanded Employer Fertility Benefits at a Single Academic Center from 2017-2021.","authors":"Alexandra M Herweck,Miranda Lm Delawalla,Caroline Reed,Traci L Carson,Avni Ahuja,Paris Chey,Maeve McNamara,Khushi Gupta,Allison Bosch,Heather S Hipp,Jennifer F Kawwass","doi":"10.1016/j.ajog.2025.04.069","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.04.069","url":null,"abstract":"BACKGROUNDRecognized by the World Health Organization as a disease, infertility carries emotional and financial burdens. With treatments like in vitro fertilization (IVF) costing approximately $12,400 (not including medications), many Americans may allocate a substantial portion of their annual income to a single assisted reproductive technology (ART) cycle. To mitigate this burden, a minority of states mandate varying levels of insurance coverage for fertility treatment. Independent of state legislation, individual employers can also provide fertility benefits. In 2019, one academic institution, in a non-mandated state, amended its insurance policy to begin providing up to $25,000 of fertility treatment. Coverage expansion may ease financial stress and promote diversity in treatment access, as data indicates racial disparities in infertility treatment uptake.OBJECTIVEOur study analyzed demographic shifts and treatment utilization in patients seeking fertility treatment before and after implementation of an expanded fertility treatment insurance benefit at a single institution.STUDY DESIGNWe conducted a retrospective chart review at a reproductive clinic in a large, urban academic hospital system from 2017 to 2021. Analyses included descriptive statistics (means, proportions) and pre-implementation (2017-2018) and post-implementation (2019-2021) periods were compared with chi-square tests, Fisher exact tests, and Mann-Whitney U tests.RESULTSFrom 2017 to 2021, 1,586 new patients accessed fertility services, including 378 prior to expanded fertility benefit coverage (2017-2018) and 1,208 after its implementation (2019-2021), representing a 162.9% increase from 2017 to 2021. There was an increase in the proportion of patients ages 38-40 years of age seeking care (12.4% vs. 17.8%), a decrease in the proportion of older patients (ages 41-42: 9.3% vs. 5.1%; age > 42: 7.4% vs. 6.7%), and no differences in the proportion of patients < 38 years (p=0.01). There were no differences in self-identified race/ethnicity before and after implementation, with patients most commonly identifying as non-Hispanic White (41.5% vs 40.0%), closely followed by non-Hispanic Black (38.6% vs 39.7%; p=0.89). After implementation, a higher proportion of women without infertility sought care (17.5% vs. 23.1%; p=0.03) specifically in the form of oocyte cryopreservation (12.2% vs 16.7%) and preconception counseling (3.4% vs 5.6%; p=0.02). There was an increase in patients pursuing oocyte cryopreservation as highest level of treatment (5.8% vs. 15.4%), but no differences in proportions of patients pursuing other treatment (p<0.001). Patient-reported infertility prior to first appointment also decreased (p<0.001).CONCLUSIONSPatient demographics and fertility treatment utilization changed after the adoption of fertility benefits at a single institution, highlighting that implementation of fertility benefits have potential to improve healthcare access and empower reproductively aged ","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"68 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143921007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reshaping the Landscape of Ovarian Cancer: Implications from the Surgery for Ovarian cancer FIGO 4 Study.","authors":"Halil Göksel Güzel,Onur Yazdan Balçık,Yusuf İlhan","doi":"10.1016/j.ajog.2025.04.063","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.04.063","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"40 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-05-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143915094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Investigation of Maternal Outcomes Following Respiratory Syncytial Virus Vaccination in the Third Trimester: Insights from a Real-World U.S. Electronic Health Records Database.","authors":"Tina Yi Jin Hsieh,James Cheng-Chung Wei,Ai-Ris Collier","doi":"10.1016/j.ajog.2025.04.067","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.04.067","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"38 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary vs interval cytoreductive surgery in stage IV ovarian cancer (SOFI-4).","authors":"Floriane Jochum,Cherif Akladios,","doi":"10.1016/j.ajog.2025.04.064","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.04.064","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"11 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Closing Gaps in Perinatal Mental Health Care in the United States.","authors":"Jiage Qian,Carrie Wolfson,Andreea A Creanga","doi":"10.1016/j.ajog.2025.04.066","DOIUrl":"https://doi.org/10.1016/j.ajog.2025.04.066","url":null,"abstract":"","PeriodicalId":7574,"journal":{"name":"American journal of obstetrics and gynecology","volume":"2 1","pages":""},"PeriodicalIF":9.8,"publicationDate":"2025-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143914819","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}