Computers and biomedical research, an international journal最新文献_第9页

Tools for Immunization Guideline Knowledge Maintenance 免疫指南知识维护工具

Computers and biomedical research, an international journal Pub Date : 1998-06-01 DOI: 10.1006/cbmr.1998.1471

Perry L. Miller, Sandra J. Frawley, Cynthia Brandt, Frederick G. Sayward

{"title":"Tools for Immunization Guideline Knowledge Maintenance","authors":"Perry L. Miller, Sandra J. Frawley, Cynthia Brandt, Frederick G. Sayward","doi":"10.1006/cbmr.1998.1471","DOIUrl":"10.1006/cbmr.1998.1471","url":null,"abstract":"<div><p>IMM/Test is a prototype software tool built to generate test cases that can be used to help test and verify the internal logic of an immunization forecasting program. A forecasting program takes as input a child's immunization history and produces recommendations as to which vaccinations are due and which should be scheduled next. IMM/Test was developed to test a specific immunization forecasting program, IMM/Serve. In addition, IMM/Test has been incorporated into a broader Web-based tool, IMM/Web, which allows the user (e.g., a member of an immunization registry staff) to customize the parameters used for immunization forecasting (e.g., the minimum ages for each dose and the minimum wait intervals between doses) to reflect local practice. IMM/Web then generates a customized set of test cases that may be used to test the user's immunization forecasting program. The user may also request that the test cases be automatically passed to IMM/Serve to analyze using the newly defined parameters. The paper describes the internal design of IMM/Test and IMM/Web and discusses certain lessons learned in the implementation of the two programs.</p></div>","PeriodicalId":75733,"journal":{"name":"Computers and biomedical research, an international journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/cbmr.1998.1471","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20547713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 13

Joint Time and Time-Frequency Optimal Detection of K-Complexes in Sleep EEG 睡眠脑电图中k -复合体的联合时频最优检测

Computers and biomedical research, an international journal Pub Date : 1998-06-01 DOI: 10.1006/cbmr.1998.1476

Cédric Richard, Régis Lengelle

引用次数: 36

An Efficient Procedure for Permutation Tests in Imaging Research 成像研究中一种有效的排列试验方法

Computers and biomedical research, an international journal Pub Date : 1998-06-01 DOI: 10.1006/cbmr.1998.1478

Dan Heckel , Stephan Arndt , Ted Cizadlo , Nancy C. Andreasen

引用次数: 5

Tools for Immunization Guideline Knowledge Maintenance 免疫指南知识维护工具

Computers and biomedical research, an international journal Pub Date : 1998-06-01 DOI: 10.1006/cbmr.1998.1472

Perry L. Miller

{"title":"Tools for Immunization Guideline Knowledge Maintenance","authors":"Perry L. Miller","doi":"10.1006/cbmr.1998.1472","DOIUrl":"10.1006/cbmr.1998.1472","url":null,"abstract":"<div><p>IMM/Def is a prototype computer program designed to facilitate the building and maintenance of a rule-based program which performs childhood immunization forecasting. An immunization forecasting program takes as input a child's immunization history and produces recommendations as to which vaccinations are due and which should be scheduled next. A significant amount of the knowledge required for immunization forecasting can be expressed in tabular form, including the parameters that indicate the minimum age when each dose may be given and the minimum intervals between doses. The choice of which of these sets of parameters apply to a particular case depends upon additional clinical logic. To perform forecasting, this logic must be applied in three temporal contexts: (1) a dose is due now, (2) a dose is not yet due, and (3) a dose must be scheduled to follow a dose which is due now. Building and maintaining this logic by hand is a formidable challenge. IMM/Def demonstrates how this task can be simplified by first defining immunization “definition logic” which can be automatically translated into if-then rules for each of the three contexts. The approach has been applied successfully to the six childhood vaccination series which are routinely administered. A key advantage is that IMM/Def allows one to have two specifications of the logic that can be examined independently and that can be cross-checked to help assure completeness, consistency, and accuracy of the logic. The paper describes how IMM/Def performs its translation and discusses several design issues and lessons learned.</p></div>","PeriodicalId":75733,"journal":{"name":"Computers and biomedical research, an international journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/cbmr.1998.1472","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20547712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

DerivFit:A Program for Rate Equation Parameter Fitting Using Derivatives 使用导数进行速率方程参数拟合的程序

Computers and biomedical research, an international journal Pub Date : 1998-04-01 DOI: 10.1006/cbmr.1998.1469

Rafał Michalski , Wojciech Rode , Andrzej Leś

引用次数: 2

Computer-Assisted Analysis of the Impact of Respiratory Quotient on Blood CO2Tension and pH Changes 呼吸商对血co2浓度和pH值变化影响的计算机辅助分析

Computers and biomedical research, an international journal Pub Date : 1998-04-01 DOI: 10.1006/cbmr.1998.1468

Ivo Giovannini, Carlo Chiarla, Giuseppe Boldrini, Gennaro Nuzzo

引用次数: 1

Detection of Spikes with Artificial Neural Networks Using Raw EEG 基于原始脑电图的人工神经网络尖峰检测

Computers and biomedical research, an international journal Pub Date : 1998-04-01 DOI: 10.1006/cbmr.1998.1475

Ö. Özdamar , T. Kalayci

{"title":"Detection of Spikes with Artificial Neural Networks Using Raw EEG","authors":"Ö. Özdamar , T. Kalayci","doi":"10.1006/cbmr.1998.1475","DOIUrl":"10.1006/cbmr.1998.1475","url":null,"abstract":"<div><p>Artificial neural networks (ANN) using raw electroencephalogram (EEG) data were developed and tested off-line to detect transient epileptiform discharges (spike and spike/wave) and EMG activity in an ongoing EEG. In the present study, a feedforward ANN with a variable number of input and hidden layer units and two output units was used to optimize the detection system. The ANN system was trained and tested with the backpropagation algorithm using a large data set of exemplars. The effects of different EEG time windows and the number of hidden layer neurons were examined using rigorous statistical tests for optimum detection sensitivity and selectivity. The best ANN configuration occurred with an input time window of 150 msec (30 input units) and six hidden layer neurons. This input interval contained information on the wave component of the epileptiform discharge which improved detection. Two-dimensional receiver operating curves were developed to define the optimum threshold parameters for best detection. Comparison with previous networks using raw EEG showed improvement in both sensitivity and selectivity. This study showed that raw EEG can be successfully used to train ANNs to detect epileptogenic discharges with a high success rate without resorting to experimenter-selected parameters which may limit the efficiency of the system.</p></div>","PeriodicalId":75733,"journal":{"name":"Computers and biomedical research, an international journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/cbmr.1998.1475","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20493652","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 75

Contribution to the Definition of the Power Bands Limits of Sleep EEG by Linear Prediction 线性预测对睡眠脑电图频带界限定义的贡献

Computers and biomedical research, an international journal Pub Date : 1998-04-01 DOI: 10.1006/cbmr.1998.1474

J.-P. Lanquart

引用次数: 4

Developing Online Support for Clinical Information System Developers: The FAQ Approach 为临床信息系统开发者开发在线支持:常见问题解答方法

Computers and biomedical research, an international journal Pub Date : 1998-04-01 DOI: 10.1006/cbmr.1998.1470

Adam Wilcox, George Hripcsak, Stephen B. Johnson, Jae-Jun Hwang, Min Wu

{"title":"Developing Online Support for Clinical Information System Developers: The FAQ Approach","authors":"Adam Wilcox, George Hripcsak, Stephen B. Johnson, Jae-Jun Hwang, Min Wu","doi":"10.1006/cbmr.1998.1470","DOIUrl":"10.1006/cbmr.1998.1470","url":null,"abstract":"<div><p><strong>Objective:</strong>We investigate a knowledge-based help system for developers of an integrated clinical information system (CIS). The first objective in the study was to determine the system's ability to answer users' questions effectively. User performance and behavior were studied. The second objective was to evaluate the effect of using questions and answers to augment or replace traditional program documentation.</p><p><strong>Design:</strong>A comparative study of user and system effectiveness using a collection of 47 veritable questions regarding the CIS, solicited from various CIS developers, is conducted. Most questions were concerning the clinical data model and acquiring the data.</p><p><strong>Measurements:</strong>Answers using current documentation known by users were compared to answers found using the help system. Answers existing within traditional documentation were compared to answers existing within question–answer exchanges (Q-A's).</p><p><strong>Results:</strong>The support system augmented 39% of users' answers to test questions. Though the Q-A's were less than 5% of the total documentation collected, these files contained answers to nearly 50% of the questions in the test group. The rest of the documentation contained about 75% of the answers.</p><p><strong>Conclusions:</strong>A knowledge-based help system built by collecting questions and answers can be a viable alternative to large documentation files, providing the questions and answers can be collected effectively.</p></div>","PeriodicalId":75733,"journal":{"name":"Computers and biomedical research, an international journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/cbmr.1998.1470","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20493651","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Modeling and Simulating Morphological Evolution in an Artificial Life Environment 人工生命环境中形态进化的建模与模拟

Computers and biomedical research, an international journal Pub Date : 1998-02-01 DOI: 10.1006/cbmr.1997.1464

Paulo Sérgio Panse Silveira, Eduardo Massad

引用次数: 6