Computers and biomedical research, an international journal最新文献_第8页

Macular Edema Computer-Aided Evaluation in Ocular Vein Occlusions 眼静脉阻塞的黄斑水肿计算机辅助评价

Computers and biomedical research, an international journal Pub Date : 1998-10-01 DOI: 10.1006/cbmr.1998.1487

L. Martı́nez-Costa , P. Marco , G. Ayala , E. de Ves , J. Domingo , A. Simó

引用次数: 13

Detection of Transient ST Segment Episodes During Ambulatory ECG Monitoring 动态心电监测中短暂ST段发作的检测

Computers and biomedical research, an international journal Pub Date : 1998-10-01 DOI: 10.1006/cbmr.1998.1483

Franc Jager , George B. Moody , Roger G. Mark

{"title":"Detection of Transient ST Segment Episodes During Ambulatory ECG Monitoring","authors":"Franc Jager , George B. Moody , Roger G. Mark","doi":"10.1006/cbmr.1998.1483","DOIUrl":"10.1006/cbmr.1998.1483","url":null,"abstract":"<div><p>Using the European Society of Cardiology ST-T Database, we have developed a Karhunen–Loève transform-based algorithm for robust automated detection of transient ST segment episodes during ambulatory ECG monitoring. We review current approaches and systems to detect transient ST segment changes and describe the architecture of our algorithm and its development. The algorithm incorporates a single-scan trajectory-recognition technique in feature space using the Mahalanobis distance function between the feature vectors. The main characteristics of the algorithm are detection of noisy beats, correction of the reference ST segment level to correct for slow ST level drift, detection of sudden significant shifts of ST deviation due to shifts of the mean electrical axis of the heart, detection of transient ST episodes, and, by tracking the QRS complex morphology, differentiation between ischemic and nonischemic ST episodes as a result of axis shifts. We compared the algorithm's performance to other recently developed algorithms and estimated its real-world performance.</p></div>","PeriodicalId":75733,"journal":{"name":"Computers and biomedical research, an international journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/cbmr.1998.1483","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20703268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 90

Volume-Preserving Smoothing of Three-Dimensional Surfaces: Application to Intravascular Ultrasound 三维表面保体积平滑:在血管内超声中的应用

Computers and biomedical research, an international journal Pub Date : 1998-10-01 DOI: 10.1006/cbmr.1998.1484

Chaohuang Zeng, Milan Sonka

引用次数: 2

An Interactive 3D Anisotropic Cellular Automata Model of the Heart 交互式三维各向异性元胞自动机心脏模型

Computers and biomedical research, an international journal Pub Date : 1998-10-01 DOI: 10.1006/cbmr.1998.1485

P. Siregar , J.P. Sinteff, N. Julen, P. Le Beux

引用次数: 46

Comparative Study of Local and Karhunen–Loève-Based ST–T Indexes in Recordings from Human Subjects with Induced Myocardial Ischemia 心肌缺血记录中局部与karhunen - lo<e:1>型ST-T指标的比较研究

Computers and biomedical research, an international journal Pub Date : 1998-08-01 DOI: 10.1006/cbmr.1998.1481

José Garcı́a , Paul Lander , Leif Sörnmo , Salvador Olmos , Galen Wagner , Pablo Laguna

{"title":"Comparative Study of Local and Karhunen–Loève-Based ST–T Indexes in Recordings from Human Subjects with Induced Myocardial Ischemia","authors":"José Garcı́a , Paul Lander , Leif Sörnmo , Salvador Olmos , Galen Wagner , Pablo Laguna","doi":"10.1006/cbmr.1998.1481","DOIUrl":"10.1006/cbmr.1998.1481","url":null,"abstract":"<div><p>In this work we studied ST–T complex changes in the ECG as result of induced ischemia. The principal aim was to determine whether global changes in the ST–T complex were more sensitive markers of ischemic alterations than those based on measurements of changes at specific locations on ST segment or T wave. High-resolution ECGs from patients undergoing percutaneous transluminal coronary angioplasty in one of the major coronary arteries were analyzed to give a description of the period from the end of active depolarization (QRS complex) to the end of active repolarization (T wave). During artery occlusion traditional local measurements of the ST–T complex were compared to global measurements based on the Karhunen–Loève transform. An ischemic change sensor parameter was estimated for each of the studied indexes showing that global measurements detected changes better in the repolarization period in a larger number of leads and with higher sensitivity (more than 85%) than was done using local measurements (sensitivity of 64% with ST level, 33% with T-wave maximum position, and 37% with T-wave maximum amplitude). Using these global indexes it was found that most cases of ST-segment changes were accompanied by T-wave changes (72% of patients). With the use of traditional indexes 23% of patients showed no changes in the repolarization period, whereas with global indexes this percentage decreased to 8%. Thus a global representation of the entire ST–T complex appears to be more suitable than local measurements when studying the initial stages of myocardial ischemia.</p></div>","PeriodicalId":75733,"journal":{"name":"Computers and biomedical research, an international journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/cbmr.1998.1481","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20645885","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 58

Myocardial Infarction—Pinpointing the Key Indicators in the 12-Lead ECG Using Data Mining 心肌梗死——利用数据挖掘确定12导联心电图的关键指标

Computers and biomedical research, an international journal Pub Date : 1998-08-01 DOI: 10.1006/cbmr.1998.1482

Kathryn E. Burn-Thornton , Lars Edenbrandt

引用次数: 15

Enhancing the Power of Record Linkage Involving Low Quality Personal Identifiers: Use of the Best Link Principle and Cause of Death Prior Likelihoods 提高涉及低质量个人标识符的记录链接的能力:使用最佳链接原则和死因先验似然

Computers and biomedical research, an international journal Pub Date : 1998-08-01 DOI: 10.1006/cbmr.1998.1480

Margaret C.M. MacLeod , Caroline A. Bray , Stephen W. Kendrick , Stuart M. Cobbe

{"title":"Enhancing the Power of Record Linkage Involving Low Quality Personal Identifiers: Use of the Best Link Principle and Cause of Death Prior Likelihoods","authors":"Margaret C.M. MacLeod , Caroline A. Bray , Stephen W. Kendrick , Stuart M. Cobbe","doi":"10.1006/cbmr.1998.1480","DOIUrl":"10.1006/cbmr.1998.1480","url":null,"abstract":"<div><p>The Heartstart Scotland study collects details of all resuscitation attempts carried out by the Scottish Ambulance Service. The linkage between records for Heartstart study subjects who died before admission to a hospital and the national file of death records maintained by the Registrar General for Scotland is described. The conditions under which the Heartstart data is collected make it inevitable that the personal identifying information on which linkage must rely tends to be relatively incomplete and of low accuracy. The linkage process was able to use the best-link principle to take maximum advantage of the fact that, because the Heartstart subjects involved had died, there was an extremely high a priori probability that they would be represented on the national deaths file. In addition, although no cause of death information was recorded on the Heartstart records, a priori expectations of the distribution of causes of death among linked death records were used. Despite these enhancements, however, clerical resolution of a proportion of the potential links generated by the automatic algorithm significantly improved the accuracy of the linkage.</p></div>","PeriodicalId":75733,"journal":{"name":"Computers and biomedical research, an international journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/cbmr.1998.1480","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20645884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 17

The Calculation of a Confidence Interval on the Absolute Estimated Benefit for an Individual Patient 个体患者绝对估计获益置信区间的计算

Computers and biomedical research, an international journal Pub Date : 1998-08-01 DOI: 10.1006/cbmr.1998.1477

Wei Li, Pascal Girard, Jean-Pierre Boissel, François Gueyffier

{"title":"The Calculation of a Confidence Interval on the Absolute Estimated Benefit for an Individual Patient","authors":"Wei Li, Pascal Girard, Jean-Pierre Boissel, François Gueyffier","doi":"10.1006/cbmr.1998.1477","DOIUrl":"10.1006/cbmr.1998.1477","url":null,"abstract":"<div><p>Physicians need a method to predict the individualized absolute therapeutic benefit before deciding which therapy to prescribe to a given patient and the confidence intervals around this estimate. We have derived a method to predict the absolute individual therapeutic benefit in a previous work. In this paper, we present a Monte Carlo simulation to estimate the bias of prediction for an individual with certain characteristics and use a bootstrap method to compute its confidence intervals. Because the bootstrap approach does not depend upon the parametric assumption for the distribution of the prediction, it can be applied to situations where the parametric distribution is unknown. Over 35,000 cases of subjects at risk of cardiovascular events were available for analysis. Our results show the 95% confidence intervals for each individual. In a clinical setting, the use of this approach makes it possible to predict the absolute therapeutic benefit for each patient (the quantity of individual benefit) with sufficient precision.</p></div>","PeriodicalId":75733,"journal":{"name":"Computers and biomedical research, an international journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/cbmr.1998.1477","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20645367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 7

A Method for a Simulation of Continuous Intracranial Pressure Curves 一种连续颅内压曲线的模拟方法

Computers and biomedical research, an international journal Pub Date : 1998-08-01 DOI: 10.1006/cbmr.1998.1479

Bernhard Schmidt , Jens Jürgen Schwarze , Marek Czosnyka , Dirk Sander , Ingo Wittich , Jürgen Klingelhöfer

引用次数: 13

An AI Approach to Dynamic Visual Field Testing 动态视野测试的人工智能方法

Computers and biomedical research, an international journal Pub Date : 1998-06-01 DOI: 10.1006/cbmr.1998.1473

K.W. Cho , X. Liu , G. Loizou , J.X. Wu

引用次数: 7