Computers and biomedical research, an international journal最新文献_第7页

A Health Information Network for Managing Innercity Tuberculosis: Bridging Clinical Care, Public Health, and Home Care 管理城市内结核病的卫生信息网络:连接临床护理、公共卫生和家庭护理

Computers and biomedical research, an international journal Pub Date : 1999-02-01 DOI: 10.1006/cbmr.1998.1496

George Hripcsak , Charles A. Knirsch , Nilesh L. Jain , Richard C. Stazesky Jr. , Ariel Pablos-Mendez , Terry Fulmer

{"title":"A Health Information Network for Managing Innercity Tuberculosis: Bridging Clinical Care, Public Health, and Home Care","authors":"George Hripcsak , Charles A. Knirsch , Nilesh L. Jain , Richard C. Stazesky Jr. , Ariel Pablos-Mendez , Terry Fulmer","doi":"10.1006/cbmr.1998.1496","DOIUrl":"10.1006/cbmr.1998.1496","url":null,"abstract":"<div><p>The purpose of this study was to use a health information network and innovative technology to coordinate tuberculosis care. An innercity medical center, a local health department, and a home care nurse service in northern Manhattan were used. The organizations were linked with computer networks. An automated decision support system with a natural language processor was used to detect tuberculosis cases and report them to the health department, and to select patients for respiratory isolation. Educational materials were placed on the World Wide Web and a Web-based kiosk. Home care nurses were outfitted with wireless pen-based computers, and data were relayed to the medical center. Automated tuberculosis case reporting resulted in time savings but not improved accuracy. Automated rules resulted in significant improvements in respiratory isolation. Kiosk educational materials were well-used. Wireless computing led to better access to information for both nurses and physicians, but not to reduction of workload. The key success element was recognition of critical priorities. It is concluded that innovative technology can facilitate the coordination of clinical care, public health, and home care.</p></div>","PeriodicalId":75733,"journal":{"name":"Computers and biomedical research, an international journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1999-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/cbmr.1998.1496","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20939830","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 35

CHRONOMERGE: An Application for the Merging and Display of Multiple Time-Stamped Data Streams 一个用于合并和显示多个时间戳数据流的应用程序

Computers and biomedical research, an international journal Pub Date : 1998-12-01 DOI: 10.1006/cbmr.1998.1492

Prakash M. Nadkarni

{"title":"CHRONOMERGE: An Application for the Merging and Display of Multiple Time-Stamped Data Streams","authors":"Prakash M. Nadkarni","doi":"10.1006/cbmr.1998.1492","DOIUrl":"10.1006/cbmr.1998.1492","url":null,"abstract":"<div><p>CHRONOMERGE is a database application that facilitates merging and display of multiple time-stamped data streams. Each stream is a table containing time-stamped values of one or more parameters (such as a panel of laboratory tests) for multiple patients, and is typically created by querying a clinical data respiratory. The data within a single stream therefore represent a pool of multiple time series. The merge operation is complex because of the numerous options to be considered, such as the granularity of the time interval for merge, and the choice of statistical aggregates. CHRONOMERGE combines multiple streams into a single stream based on patient and time, or time alone (if aggregates are to be computed across patients). It allows specification of various options through a graphical user interface and generates appropriate SQL code (or invokes procedural routines) to perform the merge. The resultant stream, or subsets of it, can then be displayed graphically. CHRONOMERGE is intended to facilitate the analysis of time-stamped data that have been extracted from repositories when standard tools (such as the time-series modules of statistics packages) are inadequate.</p></div>","PeriodicalId":75733,"journal":{"name":"Computers and biomedical research, an international journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/cbmr.1998.1492","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20752441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Author Index for Volume 31 第31卷的作者索引

Computers and biomedical research, an international journal Pub Date : 1998-12-01 DOI: 10.1006/cbmr.1998.1497

引用次数: 0

Split-and-Merge Segmentation of Magnetic Resonance Medical Images: Performance Evaluation and Extension to Three Dimensions 磁共振医学图像的分裂合并分割:性能评价及向三维的扩展

Computers and biomedical research, an international journal Pub Date : 1998-12-01 DOI: 10.1006/cbmr.1998.1489

I.N. Manousakas, P.E. Undrill , G.G. Cameron, T.W. Redpath

{"title":"Split-and-Merge Segmentation of Magnetic Resonance Medical Images: Performance Evaluation and Extension to Three Dimensions","authors":"I.N. Manousakas, P.E. Undrill , G.G. Cameron, T.W. Redpath","doi":"10.1006/cbmr.1998.1489","DOIUrl":"10.1006/cbmr.1998.1489","url":null,"abstract":"<div><p>Intensity- or edge-based methods of segmentation are often insufficiently robust to be applied to images containing complex anatomical objects, such as those seen in high-resolution magnetic resonance imaging systems. Split-and-merge techniques attempt to overcome these difficulties by using homogeneity measures. Simple modifications to the basic 2D split-and-merge method, based on the principles of simulated annealing and controlled boundary elimination, are developed and discussed. Simulated annealing reduced the number of regions by 22% with a further reduction of 21% achieved through boundary elimination. Smoother regional boundaries are also produced. These methods are extended to true 3D and quantitatively compared with their 2D counterparts. The main advantage of 3D methods is that they produce segmented volumes by directly preserving the connectivity between slices, whereas in 2D, segments have to be grouped together in a post-split-and-merge process. Finally, the properties of the 3D approach are demonstrated by the automatic quantitation of brain ventricle volume, producing estimates to within 7% of validated manual methods.</p></div>","PeriodicalId":75733,"journal":{"name":"Computers and biomedical research, an international journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/cbmr.1998.1489","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20752438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 111

Applying Computer Modeling to Examine Complex Dynamics and Pattern Formation of Tissue Growth 应用计算机模型研究组织生长的复杂动力学和模式形成

Computers and biomedical research, an international journal Pub Date : 1998-12-01 DOI: 10.1006/cbmr.1998.1490

W.P. Isele, H.P. Meinzer

引用次数: 6

Computer Assisted Neurophysiology by a Distributed Java Program 基于分布式Java程序的计算机辅助神经生理学

Computers and biomedical research, an international journal Pub Date : 1998-12-01 DOI: 10.1006/cbmr.1998.1494

Luc Jeandenans , Michel Gautero , François Grize , Igor V. Tetko , Alessandro E.P. Villa

引用次数: 2

Comparative Investigations of Algorithms for the Detection of Breaths in Newborns with Disturbed Respiratory Signals 新生儿呼吸信号干扰呼吸检测算法的比较研究

Computers and biomedical research, an international journal Pub Date : 1998-12-01 DOI: 10.1006/cbmr.1998.1493

M. Schmidt , B. Foitzik , R.R. Wauer , F. Winkler , G. Schmalisch

{"title":"Comparative Investigations of Algorithms for the Detection of Breaths in Newborns with Disturbed Respiratory Signals","authors":"M. Schmidt , B. Foitzik , R.R. Wauer , F. Winkler , G. Schmalisch","doi":"10.1006/cbmr.1998.1493","DOIUrl":"10.1006/cbmr.1998.1493","url":null,"abstract":"<div><p>The correct detection of the beginning of inspiration and expiration in the respiratory signals is an essential prerequisite for accurate lung function testing in newborns. Five algorithms for breath detection using pneumotachographically measured flow and volume signals were investigated with regard to the error rate. To compare and to evaluate the reliability of these algorithms 12 minimally and 12 severely disturbed flow and volume signals from spontaneously breathing newborns were used. With the exception of an algorithm based on Walsh-transformed signals, all algorithms work reliably (error rate <1.1%) if disturbances are minimal. In severely disturbed signals there is a great difference between the algorithms. The most robust algorithm tested (trigger of the flow signal with an additional plausibility check of the recognized breath) resulted in an error rate of <3.4%. Not all algorithms tested are suitable for real-time applications because they differ considerably in delay time for breath detection.</p></div>","PeriodicalId":75733,"journal":{"name":"Computers and biomedical research, an international journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/cbmr.1998.1493","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20752439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 40

Formal Representation of Summary Tables for Health Care Statistical Database Management 卫生保健统计数据库管理的汇总表的正式表示

Computers and biomedical research, an international journal Pub Date : 1998-12-01 DOI: 10.1006/cbmr.1998.1491

Mihoko Okada , Minoru Takaba , Shigekoto Kaihara , Masahiko Okada

引用次数: 0

Multigrid Solution of the Potential Field in Modeling Electrical Nerve Stimulation 神经电刺激模型中电位场的多网格解

Computers and biomedical research, an international journal Pub Date : 1998-10-01 DOI: 10.1006/cbmr.1998.1486

Rudi Hoekema , Kees Venner , Johannes J. Struijk , Jan Holsheimer

引用次数: 29

Experiments to Determine Whether Recursive Partitioning (CART) or an Artificial Neural Network Overcomes Theoretical Limitations of Cox Proportional Hazards Regression 确定递归划分(CART)或人工神经网络是否克服了Cox比例风险回归的理论局限性的实验

Computers and biomedical research, an international journal Pub Date : 1998-10-01 DOI: 10.1006/cbmr.1998.1488

Michael W. Kattan , Kenneth R. Hess , J.Robert Beck

{"title":"Experiments to Determine Whether Recursive Partitioning (CART) or an Artificial Neural Network Overcomes Theoretical Limitations of Cox Proportional Hazards Regression","authors":"Michael W. Kattan , Kenneth R. Hess , J.Robert Beck","doi":"10.1006/cbmr.1998.1488","DOIUrl":"10.1006/cbmr.1998.1488","url":null,"abstract":"<div><p>New computationally intensive tools for medical survival analyses include recursive patitioning (also called CART) and artificial neural networks. A challenge that remains is to better understand the behavior of these techniques in effort to know when they will be effective tools. Theoretically they may overcome limitations of the traditional multivariable survival technique, the Cox proportional hazards regression model. Experiments were designed to test whether the new tools would, in practice, overcome these limitations. Two datasets in which theory suggests CART and the neural network should outperform the Cox model were selected. The first was a published leukemia dataset manipulated to have a strong interaction that CART should detect. The second was a published cirrhosis dataset with pronounced nonlinear effects that a neural network should fit. Repeated sampling of 50 training and testing subsets was applied to each technique. The concordance index<em>C</em>was calculated as a measure of predictive accuracy by each technique on the testing dataset. In the interaction dataset, CART outperformed Cox (<em>P</em>< 0.05) with a<em>C</em>improvement of 0.1 (95% CI, 0.08 to 0.12). In the nonlinear dataset, the neural network outperformed the Cox model (<em>P</em>< 0.05), but by a very slight amount (0.015). As predicted by theory, CART and the neural network were able to overcome limitations of the Cox model. Experiments like these are important to increase our understanding of when one of these new techniques will outperform the standard Cox model. Further research is necessary to predict which technique will do best<em>a priori</em>and to assess the magnitude of superiority.</p></div>","PeriodicalId":75733,"journal":{"name":"Computers and biomedical research, an international journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1998-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1006/cbmr.1998.1488","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20703271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 74