Computer programs in biomedicine最新文献_第10页

A Monte Carlo program for photon transport using analogue sampling of scattering angle in coherent and incoherent scattering processes 利用相干和非相干散射过程中散射角模拟采样的光子输运蒙特卡罗程序

Computer programs in biomedicine Pub Date : 1983-08-01 DOI: 10.1016/0010-468X(83)90032-6

Jan Persliden

引用次数: 49

NEUREC — a program package for 3D-reconstruction from serial sections using a microcomputer NEUREC -一个程序包，用于三维重建从串行部分使用微型计算机

Computer programs in biomedicine Pub Date : 1983-08-01 DOI: 10.1016/0010-468X(83)90035-1

Heribert Gras, Franz Killmann

引用次数: 21

Computer applications in education and training: taking that first byte 计算机在教育和培训中的应用:第一个字节

Computer programs in biomedicine Pub Date : 1983-08-01 DOI: 10.1016/0010-468X(83)90038-7

Sharon McMarr

引用次数: 0

A model of regional ventilation-perfusion inhomogeneity in the avian lung 鸡肺局部通气-灌注不均匀模型的建立

Computer programs in biomedicine Pub Date : 1983-08-01 DOI: 10.1016/0010-468X(83)90021-1

S.C Hempleman , T.P Adamson, R.E Burger

{"title":"A model of regional ventilation-perfusion inhomogeneity in the avian lung","authors":"S.C Hempleman , T.P Adamson, R.E Burger","doi":"10.1016/0010-468X(83)90021-1","DOIUrl":"10.1016/0010-468X(83)90021-1","url":null,"abstract":"<div>We recorded discharge frequencies of 32 intrapulmonary chemoreceptors (IPC) during caudocranial and craniocaudal ventilation in the perfused duck lung. Blood gases, ventilatory gas flow, inspired PCO2 and PO2, and expired PCO2 measured simultaneously were used to predict regional CO2 and O2 gradients within the lung. Gas exchange was modelled in 7 log normal ventilation-perfusion compartments using mass balance differentials with an adjustable step size. CO2 and O2 interactions during exchange were modelled using the Bohr effect. P50, blood acid-base status and the CO2 dissociation relationship. Close agreement (± 1.0 Torr) between simulated arterial and expired PCO2 and observed values was achieved after forcing simulated PaO2 to converge on observed PaO2 by an iterative adjustment of the perfusive shunt or the log standard deviation of the ventilation-perfusion distribution. Using the IPC static CO2 sensitivity measured in the non-perfused lung and the CO2 gradients generated by the model, we have found evidence for a distributed multi-ending receptor system in the duck lung.</div>","PeriodicalId":75731,"journal":{"name":"Computer programs in biomedicine","volume":"17 1","pages":"Pages 11-18"},"PeriodicalIF":0.0,"publicationDate":"1983-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-468X(83)90021-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17743692","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 3

Computer applications in education and training: taking that first byte 计算机在教育和培训中的应用:第一个字节

Computer programs in biomedicine Pub Date : 1983-08-01 DOI: 10.1016/0010-468X(83)90039-9

Sharon McMarr

引用次数: 1

An integrated microprocessor-based system enhanced with graphics for the evaluation of slope-ratios and other flow-volume curve parameters 基于集成微处理器的系统，增强了对坡度比和其他流量-体积曲线参数的评估

Computer programs in biomedicine Pub Date : 1983-08-01 DOI: 10.1016/0010-468X(83)90033-8

A.H.G El-Dhaher , A.J Ahmad , T.S Hassan , H.A Kaouri , K.Y Mustafa

引用次数: 2

A digital signal processing system for EEG frequency analysis 一种用于脑电图频率分析的数字信号处理系统

Computer programs in biomedicine Pub Date : 1983-08-01 DOI: 10.1016/0010-468X(83)90023-5

T.C Hsia , R.H Kraft

引用次数: 10

A computer program for detection of segmental contraction abnormalities by the left ventricular cineangiogram 通过左心室血管造影检测节段性收缩异常的计算机程序

Computer programs in biomedicine Pub Date : 1983-08-01 DOI: 10.1016/0010-468X(83)90030-2

Yoshiaki Nose, Yoshiaki Watanabe, Masao Yokota, Motoomi Nakamura

{"title":"A computer program for detection of segmental contraction abnormalities by the left ventricular cineangiogram","authors":"Yoshiaki Nose, Yoshiaki Watanabe, Masao Yokota, Motoomi Nakamura","doi":"10.1016/0010-468X(83)90030-2","DOIUrl":"10.1016/0010-468X(83)90030-2","url":null,"abstract":"<div>A computer program which enables detection of segmental abnormalities of the left ventricular contraction was developed using the principles of Leighton et al. [Circulation 50 (1974) 121–127]. A film projector, a digitizer a graphic display and a mini-computer are used. The end-diastolic (ED) and end-systolic (ES) left ventricular silhouettes are traced from 30° right anterior oblique cineangiograms projected on a screen of the film projector. The program determines semi-automatically both apexes and longitudinal axes of the left ventricle. Lines [(N − 1) ≤ 60] are drawn perpendicular to longitudinal axes, dividing longitudinal axes into equal N segments, respectively. These perpendicular lines are extended to intersect ED and ES silhouettes at 2(N − 1) points, respectively. The distances along each of 2(N − 1) hemiaxes are defined as short axes [S-EDi and S-ESi, i = 1 ∼ 2(N − 1)]. Segmental wall contractions are expressed as a percentage of the distance from S-EDi to S-EDi, and displayed as a graph with normal values (mean ± 2 SD). The presence and extent of segmental contraction abnormalities can be evaluated quantitatively by observing a percentage of segmental wall contractions. This program greatly facilitates a correct diagnosis in clinical use.</div>","PeriodicalId":75731,"journal":{"name":"Computer programs in biomedicine","volume":"17 1","pages":"Pages 101-105"},"PeriodicalIF":0.0,"publicationDate":"1983-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-468X(83)90030-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17743694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 2

Mini-computer programs for bioequivalence testing of pharmaceutical drug formulations in two-way cross-over studies 用于双向交叉研究中药物制剂生物等效性试验的微型计算机程序

Computer programs in biomedicine Pub Date : 1983-08-01 DOI: 10.1016/0010-468X(83)90027-2

Herman P Wijnand, Cornelis J Timmer

{"title":"Mini-computer programs for bioequivalence testing of pharmaceutical drug formulations in two-way cross-over studies","authors":"Herman P Wijnand, Cornelis J Timmer","doi":"10.1016/0010-468X(83)90027-2","DOIUrl":"10.1016/0010-468X(83)90027-2","url":null,"abstract":"<div>For bioequivalence testing of pharmaceutical formulations of the same drug entity, it is not sufficient to carry out an analysis of variance on the characteristic to be evaluated (e.g., area under the plasma level vs time curve, half-life of elimination, time to plasma-peak level, plasma peak level) and to establish ‘classical’ 95% confidence intervals for the difference or the ratio of the characteristic concerned. In the past 10 years, several approaches have been proposed as an aid in decision-making: Westlake's 95% intervals, Rodda and Davis' probabilities, Fluehler's posterior probability histograms and the evaluation of the residual variation coefficient. A survey of these approaches is given, together with a discussion of their merits, their differences and their similarities. It is recommended that the final evaluation should be supported by probability density plots, which facilitate easy understanding of the differences and similarities between the various approaches. A bioequivalence study with two types of oral tablets containing bepridil, a new anti-anginal drug, is used as an example. Computer programs are presented, which enable the user to easily apply the various approaches in order to meet requirements of regulatory agencies.</div>","PeriodicalId":75731,"journal":{"name":"Computer programs in biomedicine","volume":"17 1","pages":"Pages 73-88"},"PeriodicalIF":0.0,"publicationDate":"1983-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-468X(83)90027-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"17663159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 20

A new method for automatic metaphase finding adaptable to different chromosome preparations 一种适用于不同染色体制备的中期自动发现新方法

Computer programs in biomedicine Pub Date : 1983-06-01 DOI: 10.1016/0010-468X(83)90081-8

D. Schoëvaërt-Brossault, C. Léonard, J. Selva

引用次数: 5