{"title":"Transport of charged macromolecules across a biological charged membrane","authors":"M. Van Damme, M. Prevost","doi":"10.1016/0010-468X(85)90001-7","DOIUrl":"10.1016/0010-468X(85)90001-7","url":null,"abstract":"<div><p>The glomerular capillary wall of the kidney behaves as an electronegatively charged structure consisting of three layers, the lamina densa and the two laminae rarae, which are differently chrrged. Thus, a three layer model is proposed to analyse the transport of charged macromolecules across this wall.</p><p>A modified Nernst-Planck equation describes the macromolecule flux across the wall and a Donnan equilibrium is assumed at each interface. For a given value of the fixed charge concentration in each layer, the local sieving coefficient of the macromolecule, i.e. the ratio between the concentrations in the filtrate and in the plasma, is calculated. A sieving curve which relates the sieving coefficient to the Einstein-Stokes radius of the macrosolute is obtained. The fixed charge concentrations in each layer are iteratively modified until simultaneous adjustment is achieved between calculated and experimental curves, for positively and negatively charged tracers and their neutral equivalent.</p></div>","PeriodicalId":75731,"journal":{"name":"Computer programs in biomedicine","volume":"19 2","pages":"Pages 107-117"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-468X(85)90001-7","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14955697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A.H.G. El-Dhaher , A.J. Ahmad , T.S. Hassan , K.Y. Mustafa
{"title":"Microprocessor-based system for on-line analysis of respiratory responses to exercise","authors":"A.H.G. El-Dhaher , A.J. Ahmad , T.S. Hassan , K.Y. Mustafa","doi":"10.1016/0010-468X(85)90009-1","DOIUrl":"10.1016/0010-468X(85)90009-1","url":null,"abstract":"<div><p>A microprocessor-based system was developed for the measurement and on-line calculation of values and derivatives of expiratory variables and their response to exercise. The system accepts analog signals from gas analysers, ECG electrodes and flow transducer, digitizes these signals, calculates values of required parameters and presents results on a video display. The system offers the user various options of logging and data processing. Plots of the values of calculated parameters versus exercise time and correlation between variables can be easily produced by the system. A mass storage unit was available with the system to enable the storage of calculated variables for off-line analysis. Hardcopy of displayed results and plots can be provided by the system.</p></div>","PeriodicalId":75731,"journal":{"name":"Computer programs in biomedicine","volume":"19 2","pages":"Pages 179-187"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-468X(85)90009-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15141310","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"User friendliness in microcomputer programs","authors":"Arthur T. Johnson","doi":"10.1016/0010-468X(85)90003-0","DOIUrl":"10.1016/0010-468X(85)90003-0","url":null,"abstract":"<div><p>Writing programs for use by others is not easy. Above all, one must know the group the program is written for, and try to relate the program to this group.</p></div>","PeriodicalId":75731,"journal":{"name":"Computer programs in biomedicine","volume":"19 2","pages":"Pages 127-130"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-468X(85)90003-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14955698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Two-pool model analysis of data in hemodialysis by means of programmable pocket calculator TI 59","authors":"R. Guthke , K. Günther , G. Stein , W.A. Knorre","doi":"10.1016/0010-468X(85)90010-8","DOIUrl":"10.1016/0010-468X(85)90010-8","url":null,"abstract":"<div><p>Four parameters of a two-pool model are evaluated by an iterative method using the explicit solutions of the linear differential equations. For this it was presumed that the residual renal clearance is sufficiently small. Five data pairs of measured plasma concentrations <em>c</em><sub><em>i</em></sub> for the time points <em>t</em><sub><em>i</em></sub> (<em>i</em> = 0 to 4), as well as the dialyzer and residual renal clearances (<em>K</em><sub>D</sub> and <em>K</em><sub>R</sub>), must be given and put in the calculator. A sample run is shown for urea kinetics. The parameter estimation takes about 10 min. The program is suitable to assist in the individualization of dialysis therapy.</p></div>","PeriodicalId":75731,"journal":{"name":"Computer programs in biomedicine","volume":"19 2","pages":"Pages 189-195"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-468X(85)90010-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14955702","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"III international symposium on computing in anesthesia","authors":"","doi":"10.1016/0010-468X(85)90019-4","DOIUrl":"https://doi.org/10.1016/0010-468X(85)90019-4","url":null,"abstract":"","PeriodicalId":75731,"journal":{"name":"Computer programs in biomedicine","volume":"19 2","pages":"Pages 253-264"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-468X(85)90019-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136844950","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Timing pulse and sampling programs implemented on a laboratory microcomputer","authors":"Lai-Wo Stan Leung","doi":"10.1016/0010-468X(85)90005-4","DOIUrl":"10.1016/0010-468X(85)90005-4","url":null,"abstract":"<div><p>This paper presents two programs implemented on a microcomputer for analog-to-digital (A-to-D) conversion of neurophysiological signals. The first program, TIMET, sets flexible pulse trains for the timing of the A-to-D conversions, executed by the second program, ADC8. TIMET contains options for a continuous or a triggered pulse train with variable onset delay. ADC8 allows sampling rates up to 30 kHz for one channel and 9 kHz for the maximum of 7 channels, with about 8 μs lag between channels. The digitized data are displayed with interactive gain control from keyboard input, and selected sweeps can be stored on disk files.</p></div>","PeriodicalId":75731,"journal":{"name":"Computer programs in biomedicine","volume":"19 2","pages":"Pages 143-150"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-468X(85)90005-4","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14955700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Biodyn: A program to estimate biological dynamics of human populations","authors":"Anthony Ayiomamitis , Norman C. Sullivan","doi":"10.1016/0010-468X(85)90013-3","DOIUrl":"10.1016/0010-468X(85)90013-3","url":null,"abstract":"<div><p>A microcomputer program has been developed to aid field and laboratory anthropologists and demographers estimate biological dynamics of human populations.</p></div>","PeriodicalId":75731,"journal":{"name":"Computer programs in biomedicine","volume":"19 2","pages":"Pages 217-220"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-468X(85)90013-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14955705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
B. Dahlqvist, E. Bengtsson, O. Eriksson, T. Jarkrans, B. Nordin, B. Stenkvist
{"title":"A program for logistic prediction modelling","authors":"B. Dahlqvist, E. Bengtsson, O. Eriksson, T. Jarkrans, B. Nordin, B. Stenkvist","doi":"10.1016/0010-468X(85)90016-9","DOIUrl":"10.1016/0010-468X(85)90016-9","url":null,"abstract":"<div><p>A computer program has been developed that can be used for analysing a binary outcome variable and a set of regressors of type interval with a logistic (i.e. nonlinear) model.</p></div>","PeriodicalId":75731,"journal":{"name":"Computer programs in biomedicine","volume":"19 2","pages":"Pages 235-237"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-468X(85)90016-9","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"14957760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Testing marginal homogeneity in square tables; with emphasis on matched data","authors":"M.A.A. Moussa","doi":"10.1016/0010-468X(85)90017-0","DOIUrl":"10.1016/0010-468X(85)90017-0","url":null,"abstract":"<div><p>A noniterative procedure based upon the minimum modified <em>χ</em><sup>2</sup> approach is employed to test the model of homogeneity of one-dimensional margins in square tables. Such tables may arise from matched pairs with <em>k</em> outcomes. The special case of double dichotomy (i.e. matched pairs with two outcomes) reduces to the McNemar test statistic. The case of multiple matched controls is also dealt with. The Cochran's <em>Q</em> test is used to test the marginal homogeneity in cases comparing <em>m</em> distinct matched samples in addition to testing trends in proportions. Reference is made to the equivalence between these tests and the approach of hierarchical log-linear models for testing marginal homogeneity of square tables.</p></div>","PeriodicalId":75731,"journal":{"name":"Computer programs in biomedicine","volume":"19 2","pages":"Pages 239-247"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-468X(85)90017-0","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"15012502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Author index to volume 19","authors":"","doi":"10.1016/0010-468X(85)90021-2","DOIUrl":"https://doi.org/10.1016/0010-468X(85)90021-2","url":null,"abstract":"","PeriodicalId":75731,"journal":{"name":"Computer programs in biomedicine","volume":"19 2","pages":"Pages 269-270"},"PeriodicalIF":0.0,"publicationDate":"1985-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/0010-468X(85)90021-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136844953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}