{"title":"Tightening our belts while learning to live with less.","authors":"Richard J Fugo, Martin Szanto","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"34 2","pages":"63-4"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27709721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Organ transplantation for the primary care provider: what you need to know to get your patient a new liver or kidney.","authors":"Claude A Beaty, Tyler Cymet","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Successful management of transplant patients requires an informed primary care provider with a good working relationship with the patient's medical home. Primary care physicians who are aware of the policies and criteria that regulate transplants will help their patients obtain the organs as treatment of end organ damage.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"34 2","pages":"69-76"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27709723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Uchenna E Okagbue, Luke Y J Wang, Tyler Cymet, Bruce Rabin, Rodrigo B Erlich
{"title":"A rare case of anti-Hu paraneoplastic neurologic syndrome in association with cervical cancer.","authors":"Uchenna E Okagbue, Luke Y J Wang, Tyler Cymet, Bruce Rabin, Rodrigo B Erlich","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Anti-Hu antibodies, also known as ANNA-1, are well characterized in paraneoplastic neuropathies. We present here the first known case of anti-Hu seropositivity, cerebellar ataxia, and sensory neuropathy in association with cervical cancer.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"34 1","pages":"48-50"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27578884","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prevention of venous thromboembolism in hospitalized patients.","authors":"Wilbert S Aronow","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The rationale for thromboprophylaxis is based on the high prevalence of venous thromboembolism (VTE). Use of effective methods of prophylaxis is more cost-effective and is safer than selective, intensive screening for VTE. These therapeutic options will be discussed.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"34 1","pages":"2-9"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27578972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A cardiologist's experience undergoing quadruple coronary artery bypass surgery.","authors":"Wilbert S Aronow","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This article describes the past medical history of a 76-year-old cardiologist, the symptoms which led him to have a stress echocardiogram, the results of his coronary angiography, his experience undergoing quadruple coronary artery bypass surgery, his recovery at home, his readmission and hospitalization for a massive left pleural effusion and an infection of his left foot, and his recovery at home.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"34 2","pages":"65-7; discussion 68"},"PeriodicalIF":0.0,"publicationDate":"2008-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27709722","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Hepatitis C: epidemiology, diagnosis, and management.","authors":"Marc S Itskowitz","doi":"10.1007/s12019-007-8005-8","DOIUrl":"https://doi.org/10.1007/s12019-007-8005-8","url":null,"abstract":"<p><p>Chronic hepatitis C virus (HCV) infection is a common worldwide problem. The infection may progress to cirrhosis with the subsequent development of complications including hepatocellular carcinoma. There has been substantial progress in understanding various aspects of HCV infection, including the epidemiology, virology, natural history of chronic infection, and medical therapy.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"33 2","pages":"87-93"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12019-007-8005-8","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27077627","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cinchonism in a patient taking Quinine for leg cramps.","authors":"Alex M Barrocas, Tyler Cymet","doi":"10.1007/s12019-007-0013-1","DOIUrl":"https://doi.org/10.1007/s12019-007-0013-1","url":null,"abstract":"<p><p>Quinine is often used as a treatment for benign nocturnal cramps. The use of Quinine remains controversial with conflicting studies regarding its efficacy. Quinine has a side effect profile that cannot be ignored. Cinchonism, or quinine toxicity, includes nausea, vomiting, and tinnitus. Many other side effects have been reported in the literature. A case report demonstrating the side effects of quinine is presented. We briefly review the literature on quinine and alternative medications.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"33 3","pages":"162-3"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12019-007-0013-1","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27079687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Submicrobial doxycycline and rosacea.","authors":"Ronald D Wise","doi":"10.1007/s12019-007-8003-x","DOIUrl":"https://doi.org/10.1007/s12019-007-8003-x","url":null,"abstract":"<p><p>Rosacea is a disease of inflammation with no pathogenic bacteria involved. Successful treatment of rosacea is possible without using antimicrobial preparations. Oracea capsules provide the antiinflammatory benefits of doxycycline without contributing to the development of resistance to doxycycline.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"33 2","pages":"78-81"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12019-007-8003-x","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27077624","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Disease-specific depression and outcomes in chronic heart failure: a propensity score analysis.","authors":"Ozioma C Okonkwo, Xuemei Sui, Ali Ahmed","doi":"10.1007/s12019-007-8001-z","DOIUrl":"10.1007/s12019-007-8001-z","url":null,"abstract":"<p><p>Depression is common in heart failure and is associated with increased mortality. Yet, it is often underdiagnosed and inadequately treated. Lack of disease-specific and easy-to-administer screening tools is one of the reasons for underdiagnosis of depression in heart failure. We examined the effect of depression, as diagnosed by a single question about depression caused by heart failure symptoms and affecting quality of life, in a propensity score-matched cohort of heart failure patients. Of the 581 patients enrolled in the quality-of-life sub-study of the Digitalis Investigation Group trial, 298 (51%) reported that their heart failure prevented them from living as they wanted during the last month by making them feel depressed. Seventy patients (23%) who reported that they felt \"much\" or \"very much\" depressed were considered depressed for the purpose of this study. We matched 47 (67%) of these depressed patients with 47 patients from among the 283 patients without depression. Kaplan-Meier and matched Cox regression analyses were used to estimate associations of depression with mortality and hospitalizations during a median follow up of 33 months. Compared with 8 (17%) deaths in patients in the non-depressed group, 19 (40%) of those in the depressed group died from all causes [unadjusted hazard ratio (HR), 1.55; 95% confidence interval (CI), 1.004-2.39; p=0.048]. Adjustment for propensity scores (adjusted HR, 1.77; 95% CI, 1.04-3.00; p=0.034) or other covariates (adjusted HR, 1.85; 95% CI, 1.12-3.04; p=0.016) did not alter the association between depression and mortality. The association, however, became marginally significant in the matched cohort (HR, 2.50; 95% CI, 0.97-6.44; p=0.058). There was no significant association between depression and hospitalization. Baseline depression, identified by a single disease-specific question, was associated with increased mortality among ambulatory chronic heart failure patients.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"33 2","pages":"65-70"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2659298/pdf/nihms78031.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27077621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Posttraumatic stress disorder in primary care patients.","authors":"David Bronson, Kathleen Franco, Kumar Budur","doi":"10.1007/s12019-007-8018-3","DOIUrl":"https://doi.org/10.1007/s12019-007-8018-3","url":null,"abstract":"<p><p>Posttraumatic stress disorder (PTSD) is a common psychiatric condition. PTSD patients can present with a wide variety of symptoms, and these patients are also at a higher risk of other physical, psychiatric, and substance abuse problems. Recent advances in the treatment of this condition can help the majority of patients with PTSD. Early detection, initiation of appropriate treatment, and timely referral are crucial in the proper management of PTSD.</p>","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"33 4","pages":"208-15"},"PeriodicalIF":0.0,"publicationDate":"2007-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1007/s12019-007-8018-3","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"27099650","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}