{"title":"Idiopathic intracranial hypertension.","authors":"Z. Tessler, M. Marcus","doi":"10.1017/9781108684729.123","DOIUrl":"https://doi.org/10.1017/9781108684729.123","url":null,"abstract":"To the Editor: Kleinschmidt et al.1 reported that relative to controls, patients with idiopathic intracranial hypertension (IIH) had a higher prevalence of adverse health problems and health-related psychosocial concerns, as well as higher levels of depression and anxiety measured by questionnaire. The authors suggest that while obesity may be related to depression and lower quality of life in patients with IIH, other factors may be involved. Eighteen years ago, my colleagues and I described seven patients,2 including two sisters,3 who developed IIH 2 weeks following the resolution of a major depressive episode. We noted that both IIH and major depression are associated with disturbances in the hypothalamic-pituitary-adrenal axis, and speculated that declining corticosteroid levels in a resolving depression may result in impaired cerebrospinal fluid absorption and development of IIH. Thus, a link may exist between neuroendocrine disturbances, depressive symptoms, and quality of life in patients with IIH. I agree with Kleinschmidt et al. that a relation exists between IIH and depressive illness, and suggest that at least in some patients, it is a result of neuroendocrine alterations common to both conditions. Additional research is needed to examine the contributions of psychosocial and neurobiologic (including neuroendocrine) factors to depressive symptoms and quality of life in patients with IIH.","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"17 1 1","pages":"13-7"},"PeriodicalIF":0.0,"publicationDate":"2019-05-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1017/9781108684729.123","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47242998","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pulmonary aspiration.","authors":"T. lee-chiong","doi":"10.1093/med/9780190237691.003.0032","DOIUrl":"https://doi.org/10.1093/med/9780190237691.003.0032","url":null,"abstract":"This case focuses on pulmonary aspirations during the perioperative period by asking the question: What is the incidence and clinical significance of pulmonary aspiration during the perioperative period based on the predictive potential of common clinical findings? This study showed that pulmonary aspiration among surgical patients was associated with increasing American Society of Anesthesiologists (ASA) physical status and emergency procedures. Patient with clinically apparent pulmonary aspiration who do not develop signs or symptoms within 2 hours in the immediate postoperative period are unlikely to have respiratory sequelae.","PeriodicalId":75729,"journal":{"name":"Comprehensive therapy","volume":"23 6 1","pages":"371-7"},"PeriodicalIF":0.0,"publicationDate":"2018-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43115851","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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