T. Angerpointner, O. Linderkamp, H. Stallinger, K. Riegel
{"title":"[Cardiovascular adaptation of the newborn to stress situations: effects of hypoxia on newborn and 14-day-old piglets (author's transl)].","authors":"T. Angerpointner, O. Linderkamp, H. Stallinger, K. Riegel","doi":"10.1007/978-3-642-67617-8_11","DOIUrl":"https://doi.org/10.1007/978-3-642-67617-8_11","url":null,"abstract":"","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":"67 3","pages":"53-6"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"51017149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
W Seybold-Epting, C Huth, K van Deyk, E Voigt, H E Hoffmeister
{"title":"[Influence of left atrial pressure on left ventricular function after extracorporeal circulation (author's transl)].","authors":"W Seybold-Epting, C Huth, K van Deyk, E Voigt, H E Hoffmeister","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 10 patients with coronary heart disease, in 9 with advanced mitral and in 11 with aortic valve disease left ventricular function curves were constructed by volume loading immediately after cardiopulmonary bypass. After aortocoronary bypass surgery an approximately linear correlation between both cardiac index and stroke volume index and left ventricular filling pressure was demonstrated. After aortic and mitral valve replacement increase in left ventricular filling pressure above 15 mm Hg failed to result in significant increase in CI and SVI. Apparently, volume loading has limited effects in regulating left ventricular function in advanced aortic and mitral valve disease.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"295-9"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18017284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M Fischer, S von Sommoggy, L Stötter, P Bottermann, P Schleicher, G Blümel
{"title":"[Temporary hepatic support by extracorporeal baboon liver perfusion in acute hepatic failure (author's transl)].","authors":"M Fischer, S von Sommoggy, L Stötter, P Bottermann, P Schleicher, G Blümel","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Eight patients in acute hepatic failure were treated by a total of 41 extracorporeal baboon liver perfusions. Only one has survived to the present. Parameters of good function proved to be oxygen consumption and bile production. Highly elevated aromatic amino acids decreased significantly during one single passage through an extracorporeal perfused baboon liver, as did ammonia while urea increased significantly. The prognosis of these very ill patients can be improved only when the regeneration of their damaged livers starts up again during temporary hepatic support therapy.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"145-8"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18204551","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Long-term observation after implantation of a carbon fiber-reinforced carbon hip joint endoprosthesis in foxhounds (author's transl)].","authors":"D Wolter, L Claes, R Neugebauer, C Eggers","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A hip-joint endoprosthesis, comprising a carbon fiber-reinforced stem, aluminum oxide head, and polyethylene acetabular cup, was studied in vivo trials in ten foxhounds after implantation with bone cement. Observations over 6 months and 1 year demonstrated that carbon fiber-reinforced carbon exhibits adequate strength for use as a stem material under the observed conditions.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"27-30"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18398746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D Follette, K Fey, H Becker, R Foglia, D Steed, D G Mulder, G D Buckberg
{"title":"Superiority of blood cardioplegia over asanguinous cardioplegia--an experimental and clinical study.","authors":"D Follette, K Fey, H Becker, R Foglia, D Steed, D G Mulder, G D Buckberg","doi":"10.1007/978-3-642-67617-8_58","DOIUrl":"https://doi.org/10.1007/978-3-642-67617-8_58","url":null,"abstract":"<p><p>This study compares experimental and clinical results using both an asanguinous and sanguinous vehicle for delivering the cardioplegic solution. Animals receiving blood cardioplegia had better left ventricular function after unclamping, significantly less post-ischemic myocardial edema, and a better ability to augment flow and oxygen consumption. Patients receiving blood cardioplegia had also better myocardial performance with high cardiac outputs and lower left atrial pressure, and showed less evidence of myocardial damage. We conclude that oxygenation of the cardioplegic solution provides superior myocardial protection to that seen when the same solution is used in an asanguinous vehicle.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"279-83"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18398748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Animal studies on pancreatic encephalopathy (author's transl)].","authors":"D Grossner, R Laas","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In the albino rat pancreatic juice was chronically introduced into the circulatory system. Even when the blood brain barrier was transiently opened this procedure did not affect the central nervous system, as revealed by polyphysiographic and neuropathologic analysis.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"179-83"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18399886","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[The relationship between oral glucose tolerance and gastric emptying in duodenal ulcer patients (author's transl)].","authors":"R Bittner, H G Beger, M Meves","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>In 50 patients with duodenal ulcer disease before the operation and early postoperatively after SPV there were performed simultaneously 54 measurements of halflife of gastric emptying (T 1/2) and of pattern of oral glucose tolerance curve. It could be shown that there is a close relationship between the type of disturbance of gastric emptying and the pattern of glucose curve. In addition it could be proved that there is a significant correlation between the T 1/2 and the 180-min.-glucose concentration.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"213-6"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18399894","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Adjuvant therapy of soft-tissue sarcomas: intraoperative--postoperative chemotherapy (author's transl)].","authors":"O Bertermann, H Haussmann","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>3 mg of 3,4 benzpyrene were injected subcutaneously into the neck of 90 male SD rats. After 140 days, fibrosarcomas developed in the same place. At a size of 2--4 g, the tumor was completely removed according to surgical rules. One group was operated only, whereas the other groups were subjected to operation and intraoperative or postoperative chemotherapy (CYVADIC). It could be shown that operation in combination with a postoperative chemotherapy significantly lengthens the survival period and reduces local recurrences, contrary to operation alone. Chemotherapy started intraoperatively does not increase the survival period. The considerable toxicity is an essential factor limiting the therapeutic process, although it reduces local recurrences. We think that the tumors of chemical genesis present a suitable model in addition to the graft tumors in testing new treatment forms against malignant diseases.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"329-32"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18401353","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Neidhardt, P O Schwille, W Engelhardt, C Gebhardt, D Scholz, F P Gall
{"title":"[Intravenous glucose tolerance and islet cell function following pancreatic duct occlusion in rats (author's transl)].","authors":"J Neidhardt, P O Schwille, W Engelhardt, C Gebhardt, D Scholz, F P Gall","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Microsurgery, intraductal pancreatic occlusion by an Ethibloc bolus and intravenous glucose load in the rat enable investigations to be made into the feed-back relationships between occlusion-induced acinar atrophy and the response of the islet hormones insulin, glucagon, somatostatin, and glucose tolerance. Thirteen days after duct occlusion the latter is moderately delayed from 40-60 min, serum insulin is lowered, plasma somatostatin unchanged, and plasma glucagon moderately elevated, as compared with sham-operated control animals. It is suggested that the employed experimental conditions reveal an exo-endocrine pancreatic functional axis, but that the results obtained are not representative for states with an intact entero-insular axis.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"173-7"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18040282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Beyer, R Schosser, P Conzen, W Funk, P Beckenlechner, K Messmer
{"title":"[Regional blood flow in splanchnic organs during positive end-expiratory pressure ventilation (author's transl)].","authors":"J Beyer, R Schosser, P Conzen, W Funk, P Beckenlechner, K Messmer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>An experimental study was performed on 10 dogs to evaluate the effect of positive end-expiratory pressure ventilation (PEEP) on hemodynamics and regional blood flow (RBF). The following conclusions can be drawn from the results of this study: 1) PEEP leads to a significant reduction of cardiac output (CO). 2) Total blood flow to the preportal splanchnic organs, and consequently the portal venous flow, decreases in proportion to the reduction of CO. Within the splanchnic area, there is a redistribution of RBF in favour of the small and large intestines, at the expense of stomach and pancreas. 3) The arterial blood flow to the liver is only moderately affected. 4) The observed changes of RBF may in part contribute to the complications of the splanchnic organs occurring in PEEP-ventilated patients. 5) PEEP should be used only when strictly indicated; close monitoring of organ function appears mandatory in these patients.</p>","PeriodicalId":75704,"journal":{"name":"Chirurgisches Forum fur experimentelle und klinische Forschung","volume":" ","pages":"239-42"},"PeriodicalIF":0.0,"publicationDate":"1980-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18040284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}