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[New trends in the treatment of Parkinson's disease]. [帕金森病治疗的新趋势]。
Ceskoslovenska neurologie a neurochirurgie Pub Date : 1991-09-01
L Lisý
{"title":"[New trends in the treatment of Parkinson's disease].","authors":"L Lisý","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75690,"journal":{"name":"Ceskoslovenska neurologie a neurochirurgie","volume":"54 4","pages":"196-8"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12972161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Tumor compression of the conus and cauda]. [肿瘤压迫圆锥和尾]。
Ceskoslovenska neurologie a neurochirurgie Pub Date : 1991-09-01
S Grammetbauerová
{"title":"[Tumor compression of the conus and cauda].","authors":"S Grammetbauerová","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The author analyzed a group of 17 patients with spinal tumours with symptoms of compression of the conus or cauda. Early clinical symptoms were sought and the entire clinical course before surgery was evaluated. The objective clinical finding was compared with the surgical one. Causes of diagnostic errors were analyzed. Most frequently a discogenic or other vertebrogenic cause of complaints was suspected. In all patients a local or root symptoms were the first manifestation of the disease. From the investigation ensues that a tumour must be considered when pain radiates into both lower extremities, in case of striking stiffness of the spine up to the neck and in case of damage of the higher lumbar roots. Tumours are more frequently located higher than prolapsed discs with manifestations of caudal compression. When bone structures are affected in primary tumours, the objective clinical finding may be very sparse. Tumours at the borderline of Th-L may be manifested by root symptoms L5 or S1. During PMG attention is focused lower, usually a prolapsed disc of L4/5 or L5/S1 is suspected and the tumour may be missed. Values of cerebrospinal fluid proteins in fluid collected at the lumbar level were high in all patients of the group.</p>","PeriodicalId":75690,"journal":{"name":"Ceskoslovenska neurologie a neurochirurgie","volume":"54 4","pages":"204-7"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12972165","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Congenital myasthenic syndrome]. [先天性肌无力综合征]。
Ceskoslovenska neurologie a neurochirurgie Pub Date : 1991-09-01
P Spalek
{"title":"[Congenital myasthenic syndrome].","authors":"P Spalek","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75690,"journal":{"name":"Ceskoslovenska neurologie a neurochirurgie","volume":"54 4","pages":"198-200"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12972163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Congenital myasthenic syndrome]. [先天性肌无力综合征]。
Ceskoslovenska neurologie a neurochirurgie Pub Date : 1991-09-01 DOI: 10.32388/k32uou
P. Špalek
{"title":"[Congenital myasthenic syndrome].","authors":"P. Špalek","doi":"10.32388/k32uou","DOIUrl":"https://doi.org/10.32388/k32uou","url":null,"abstract":"Congenital myasthenic syndrome is a group of conditions characterized by muscle weakness (myasthenia) that worsens with physical exertion. The muscle weakness typically begins in early childhood but can also appear in adolescence or adulthood. Facial muscles, including muscles that control the eyelids, muscles that move the eyes, and muscles used for chewing and swallowing, are most commonly affected. However, any of the muscles used for movement (skeletal muscles) can be affected in this condition. Due to muscle weakness, affected infants may have feeding difficulties. Development of motor skills such as crawling or walking may be delayed. The severity of the myasthenia varies greatly, with some people experiencing minor weakness and others having such severe weakness that they are unable to walk.","PeriodicalId":75690,"journal":{"name":"Ceskoslovenska neurologie a neurochirurgie","volume":"54 4 1","pages":"198-200"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69632930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 21
[Anterior choroidal artery syndromes]. 前脉络膜动脉综合征。
Ceskoslovenska neurologie a neurochirurgie Pub Date : 1991-09-01
P Drábek
{"title":"[Anterior choroidal artery syndromes].","authors":"P Drábek","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Three cases of anterior choroidal artery territorial infarction, diagnosed by computerized tomography, with the triad of hemiplegia, hemianaesthesia and hemianopia, pure motor stroke and ataxic hemiparesis are described. Major and minor (lacular) infarctions in the territory of the anterior choroidal artery involve almost exclusively the basal segment of the posterior limb of the internal capsule and manifest themselves by symptoms of long pathway lesion. Based on the published case reports and the authors' own observations, the complete capsular syndrome characterized by the triad of hemiplegia, hemianaesthesia and hemianopia was differentiated from partial capsular syndromes including the following forms: pure motor stroke, pure sensory stroke, sensorimotor stroke, sensory stroke with hemiataxia, ataxic hemiparesis, dysarthria and/or clumsy hand, and homonymous hemianopia (quadrantanopia or sectoranopia). The characteristic features of the above types of capsular syndromes were analyzed. Distant symptoms of territorial infarctions involving the anterior choroidal artery are transcortical sensory or motor aphasias and construction apraxia in the dominant hemisphere, left side perception failure and visual-construction apraxia in the non-dominant hemisphere, and cerebellar hemiataxia. These distant symptoms are a manifestation of distant cortical or cerebellar metabolic depression due to the mechanism of diaschisis.</p>","PeriodicalId":75690,"journal":{"name":"Ceskoslovenska neurologie a neurochirurgie","volume":"54 4","pages":"208-11"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12972166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cerebellar malacias in younger patients]. [年轻患者的小脑恶性疟疾]。
Ceskoslovenska neurologie a neurochirurgie Pub Date : 1991-09-01
K Urbánek, J Bartosek, I Vlachová
{"title":"[Cerebellar malacias in younger patients].","authors":"K Urbánek,&nbsp;J Bartosek,&nbsp;I Vlachová","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Based on four observations of cerebellar malacia in patients aged 40-45 years the authors describe the clinical picture of the disease, characterized by acute fierce occipital headache associated with nausea and vomiting. Focal cerebellar and stem symptoms develop frequently after a latency of several hours or days. None of the patients had signs of advanced arteriosclerosis or arterial hypertension:in two during the premorbid period arteriospastic manifestations were present--in one migraine, in the other angina pectoris. In three patients CT revealed bilateral malatic cerebellar affection, in one instance bilateral affection could be assumed from correlation of the clinical and CT finding. One patient died, necropsy revealed extensive malatic foci in both cerebellar hemispheres, while the finding on the entire vascular system was normal. Based on these observations and similar reports in the literature the authors discuss the possibility that arteriospasms are the decisive pathogenetic factor in the development of cerebellar malacia in young and middle age. The authors emphasize the importance of secondary oedematous changes for the prognosis and recommend for therapy a combination of common vasoactive substances with intensive antioedematous treatment and administration of calcium antagonists.</p>","PeriodicalId":75690,"journal":{"name":"Ceskoslovenska neurologie a neurochirurgie","volume":"54 4","pages":"212-4"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12971216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Somatosensory evoked potentials in workers exposed to toluene]. [接触甲苯工人的体感诱发电位]。
Ceskoslovenska neurologie a neurochirurgie Pub Date : 1991-09-01
I Stĕtkárová
{"title":"[Somatosensory evoked potentials in workers exposed to toluene].","authors":"I Stĕtkárová","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of our study was to evaluated by means of SEPs possible subclinical impairment of the nervous system during long-lasting toluene exposure. A group of 36 rotogravure printers (men, mean age 39.3 +/- 11.6 years) exposed to toluene from a polygraphic plant in Prague was investigated. The severity of toluene exposure was documented by the measurements of toluene concentration in the breathing zone air, by the toluene concentration in blood and by biological monitoring (urinary hippuric acid concentration). The duration of exposure was 0.1-41.0 (mean 12.0) years. Somatosensory evoked potentials (SEPs) elicited by stimulation of the median a tibial nerves, clinical neurological examinations and laboratory tests were performed on each worker. The results of SEPs investigations were compared with findings in a control group of 23 healthy men (mean age 31 +/- 10 years). Most of printers abused alcohol regularly. Peripheral conduction velocities in both extremities and central conduction time in case of lower limb stimulation were decreased statistically significant (P less than 0.05). All abnormalities of SEPs at peripheral and/or spinal and cortical levels were found in 8 cases, of these in 3 workers were found the SEP abnormalities of \"central\" type (the increased central conduction time at normal conduction values in the periphery). An impairment of all SEP pathways was found in 2 workers. Our results indicate an impairment in both central and peripheral parts of nervous system. Peripheral abnormalities could be interpreted as an incipient ethylic polyneuropathy and central abnormalities as an early sign of subclinical dysfunction at spinal and cortical levels due to toluene exposure potentiated by alcohol consumption.</p>","PeriodicalId":75690,"journal":{"name":"Ceskoslovenska neurologie a neurochirurgie","volume":"54 4","pages":"215-9"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12971217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Low-molecular transfer factor and its use in the treatment of amyotrophic lateral sclerosis]. [低分子转移因子及其在肌萎缩性侧索硬化治疗中的应用]。
Ceskoslovenska neurologie a neurochirurgie Pub Date : 1991-09-01
O Nevsímal, J Pekárek, K Koubek, K Cech, Z Sonková
{"title":"[Low-molecular transfer factor and its use in the treatment of amyotrophic lateral sclerosis].","authors":"O Nevsímal,&nbsp;J Pekárek,&nbsp;K Koubek,&nbsp;K Cech,&nbsp;Z Sonková","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>A low-molecular leukocyte dialysate, suppressor transfer factor (STF), exerting a stimulating effect on CD8 subpopulations in man, was administered to 17 patients with amyotrophic lateral sclerosis (ALS). Following three s.c. injections of STF, activation of CD8 subpopulations was noted in 11 patients while a decrease in CD4 in seven. Progression of the disease was found to slow in nine outpatients administered STF injections at an interval of 3-4 weeks. No therapeutic effect was seen in four patients in whom STF injection failed to show stimulating activity on lymphocyte subpopulations. Remission of the stimulating effect of STF occurs within four weeks. No side effects were seen in any of the patients treated. The effect of STF on immune reactivity and on the clinical course of ALS supports the hypothesis of autoimmune character of the disease.</p>","PeriodicalId":75690,"journal":{"name":"Ceskoslovenska neurologie a neurochirurgie","volume":"54 4","pages":"220-2"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12971218","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Computer tomography in the diagnosis of neuromuscular diseases in children]. 计算机断层扫描在儿童神经肌肉疾病诊断中的应用
Ceskoslovenska neurologie a neurochirurgie Pub Date : 1991-09-01
J Hájek, A Zouhar, T Nebeský, Z Kudlicková, Z Lukás
{"title":"[Computer tomography in the diagnosis of neuromuscular diseases in children].","authors":"J Hájek,&nbsp;A Zouhar,&nbsp;T Nebeský,&nbsp;Z Kudlicková,&nbsp;Z Lukás","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Recently in the literature occasional reports were published on the use of computed tomography (CT) in the diagnosis of neuromuscular diseases. The authors compared in a group of 23 children aged 3 to 15 years the results of clinical, laboratory, electromyographic, bioptic and CT findings on muscles. Only in four children the result of CT did not correlate with the clinical finding because of the incipient stage of the disease with structural changes which were yet only slightly expressed. Consistent with data in the literature it was possible from the CT to differentiate primary myopathies from neurogenic ones. The objective of the work was to prove the assets of the new method in the diagnosis of neuromuscular diseases, in particular in young children who do not cooperate during routine EMG examinations. There CT is an important guide for selective EMG and in particular for aimed bioptic studies which still hold priority in the specification of the disease. In already diagnosed and treated patients it is possible to investigate by means of CT the course of the disease by a non-invasive approach.</p>","PeriodicalId":75690,"journal":{"name":"Ceskoslovenska neurologie a neurochirurgie","volume":"54 4","pages":"201-3"},"PeriodicalIF":0.0,"publicationDate":"1991-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12972164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[West's syndrome--infantile myoclonic spasms]. [韦斯特综合症——婴儿肌阵挛性痉挛]。
Ceskoslovenska neurologie a neurochirurgie Pub Date : 1991-07-01
J Hadac
{"title":"[West's syndrome--infantile myoclonic spasms].","authors":"J Hadac","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The article is a review of contemporary knowledge of the so-called West syndrome. It deals with the definition, aetiology, clinical aspects, therapy and prognosis of this disease. In addition to the clinical picture of West's syndrome the author describes also recently described units which may fuse with this syndrome or mutually. The author deals on purpose in more detail with treatment of West's syndrome, in particular steroid administration (specially ACTH and its synthetic derivatives) as among our neurologists there are still very controversial views as regards indication and control of steroid treatment, sometimes associated with certain not always rational prejudices.</p>","PeriodicalId":75690,"journal":{"name":"Ceskoslovenska neurologie a neurochirurgie","volume":"54 3","pages":"166-73"},"PeriodicalIF":0.0,"publicationDate":"1991-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12914431","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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