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Incongruent parenthood in a Mexican mestizo population as determined by HLA typing. 由HLA分型确定的墨西哥混血儿群体中的不一致亲子关系。
Archivos de investigacion medica Pub Date : 1991-01-01
J A Giménez-Scherer, J Arellano, C Zavala, L Vázquez, M López Osuna, R Kretschmer
{"title":"Incongruent parenthood in a Mexican mestizo population as determined by HLA typing.","authors":"J A Giménez-Scherer,&nbsp;J Arellano,&nbsp;C Zavala,&nbsp;L Vázquez,&nbsp;M López Osuna,&nbsp;R Kretschmer","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The incidence of incongruent parenthood was determined by confronting the declared familial relationship of 98 father-mother-son/daughter trinomials (drawn from the Centro Médico Nacional-IMSS (CMN-IMSS) Kidney Transplant Program) with their HLA-A and B antigens. Fourteen (14.3%) discrepant cases were found: three each with the putative father (3.1%) or with the putative mother (3.1%), two with either father or mother (though impossible to determine precisely with whom) (2.0%), and six with both parents (6.1%). Several possible explanations of these findings were considered, such as out-of-wedlock pregnancies, complex known or unknown, declared or undeclared social circumstances frequently related to the population studied (i.e. imminent kidney transplantation) and technical pitfalls. These data underscore the level of possible \"noise\" and imprecision in population genetics; genetic-epidemiology and transplantation programs.</p>","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"22 1","pages":"95-100"},"PeriodicalIF":0.0,"publicationDate":"1991-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12983028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Changes in hemoglobin in patients with hemolytic anemia]. 溶血性贫血患者血红蛋白的变化。
Archivos de investigacion medica Pub Date : 1990-10-01
G Pérez, M E de la Peña, A Esparza, A Mejía, V Vázquez, J C Aguilar Luna, J González, B López-Guido, M L Ornelas, B Ibarra
{"title":"[Changes in hemoglobin in patients with hemolytic anemia].","authors":"G Pérez,&nbsp;M E de la Peña,&nbsp;A Esparza,&nbsp;A Mejía,&nbsp;V Vázquez,&nbsp;J C Aguilar Luna,&nbsp;J González,&nbsp;B López-Guido,&nbsp;M L Ornelas,&nbsp;B Ibarra","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Hb alterations studied throughout 2 years in 129 patients are reported, these patients had hemolytic anemia or the possibility of a hemoglobinopathy : 5 were heterozygotes to thalassemia b; 3 were compound-heterozygote of thalassemia a1 and thalassemia a2; 2 for thalassemia b and 2 for thalassemia b and Hb S; 2 homozygotes and 2 heterozygotes for Hb S; 2 was bearing unstable Hb and the other had Hereditary Persistence of Hb F. These results allow the conclusion that thalassemia is the Hb alteration which most frequently causes hemolytic anemia in our population and underscores the importance of the study of these pathologies in selected populations.</p>","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"21 4","pages":"385-8"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12834542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Cross-cultural comparisons of the Parenting Inventory for Adults and Adolescents]. [成人和青少年父母教养问卷的跨文化比较]。
Archivos de investigacion medica Pub Date : 1990-10-01
M Díaz-Romero, B Fonseca-Rodríguez, P Solís-Cámara
{"title":"[Cross-cultural comparisons of the Parenting Inventory for Adults and Adolescents].","authors":"M Díaz-Romero,&nbsp;B Fonseca-Rodríguez,&nbsp;P Solís-Cámara","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>This paper compares the normative point count of the Parenting Inventory for Adults and Adolescents (PIAA) with the points of the fathers of a family (n = 336) and adolescents (n = 357) in the city of Guadalajara. The comparisons were studied in the four dimensions of paternity which have proven clinically and experimentally valid for detection of child abuse and maltreatment. An analysis of the points obtained by fathers of children in private and public schools, as well as the points acquired by Mexican female adolescents were compared with white and black adolescents (in USA), as well as pregnant and non-pregnant ones. The object of the study was to know the point count of Mexican females on the PIAA, and contrast the count with those considered normative and those of pregnant adolescents, who are considered a high risk due to paternal abuse. The results show the Mexican fathers acquire less points with respect to the adolescents, when compared with the respective normative tables. The significance of these facts of low point count is discussed in terms of identifying child abuse and maltreatment in the Mexican child population of different social and economic strata as compared with other risk groups.</p>","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"21 4","pages":"319-23"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12834638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of diet composition on the reactivity pattern to the zinc-iodide/osmium-tetroxide mixture of the rat pancreatic acinar tissue. 日粮组成对大鼠胰腺腺泡组织对碘化锌/四氧化锇混合物反应模式的影响。
Archivos de investigacion medica Pub Date : 1990-10-01
G Tapia-Arizmendi, A R del Angel, J Arauz-Contreras, A Feria-Velasco
{"title":"Effects of diet composition on the reactivity pattern to the zinc-iodide/osmium-tetroxide mixture of the rat pancreatic acinar tissue.","authors":"G Tapia-Arizmendi,&nbsp;A R del Angel,&nbsp;J Arauz-Contreras,&nbsp;A Feria-Velasco","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>When adult rat pancreatic exocrine tissue is incubated in zinc-iodide/osmium-tetroxide (ZIO) mixture, 3 cell types are recognized depending their degree of impregnation: intensely impregnated (I-PAC), moderately impregnated (M-PAC), and non-impregnated (N-PAC) cells. Their distribution in pancreatic head was 8%, 46% and 46% respectively; whereas in the tail, it was 7%, 35% and 58% respectively. With the purpose to know whether those variations in ZIO-impregnation had some relation with the diet components, 7 groups of 30-day old male rats (n = 5 each) were maintained for 40 days with the following diets: control (C), high-protein (HP), low-protein (hP), high-lipid (HL), low-lipid (hL), high-dextrin (HD) and low-dextrin (hD) diets. Fragments of head and tail were incubated in ZIO mixture, embedded in epoxy resins and cut. Sections were examined unstained under a light microscope. The most striking features in the head were seen with hP, hL and particularly with HD diets. In tail tissue, the most relevant changes were seen with hP, hD and especially with HL diets. It is concluded that there could be a regional acinar cell populations related to preferential production of digestive enzymes in pancreatic head, body and tail, which would need to be further investigated.</p>","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"21 4","pages":"367-74"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12890712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Genetically caused deafness: prospective study of 109 children in a special school]. [遗传性耳聋:一所特殊学校109名儿童的前瞻性研究]。
Archivos de investigacion medica Pub Date : 1990-10-01
M L Ramírez-Dueñas, M C Ramírez-Dueñas, E Matute, J M Cantú
{"title":"[Genetically caused deafness: prospective study of 109 children in a special school].","authors":"M L Ramírez-Dueñas,&nbsp;M C Ramírez-Dueñas,&nbsp;E Matute,&nbsp;J M Cantú","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>109 deaf children were studied prospectively, in a special school, with an interdisciplinary focus. Clinical and audiologic studies were performed on several members of the family, in the first degree, of outstanding cases. 48 cases (44%) were identified as being of genetic etiology, 20 were acquired cases of deafness and 41 cases lacked sufficient data to reach an etiologic diagnosis.</p>","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"21 4","pages":"299-303"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12834699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Agglutinating and immobilizing activity of an ethanol extract of Bursera fagaroides on human and other mammalian spermatozoa]. [法氏囊精乙醇提取物在人类和其他哺乳动物精子上的凝集和固定化活性]。
Archivos de investigacion medica Pub Date : 1990-10-01
R L Huacuja, N M Delgado, L A Carranco, L R Reyes, G A Rosado
{"title":"[Agglutinating and immobilizing activity of an ethanol extract of Bursera fagaroides on human and other mammalian spermatozoa].","authors":"R L Huacuja,&nbsp;N M Delgado,&nbsp;L A Carranco,&nbsp;L R Reyes,&nbsp;G A Rosado","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Human spermatozoa and those obtained from mouse epididymis incubated in ethanolic from mouse epididymis incubated in ethanolic extracts of the cortex of Bursera fagaroides became agglutinated and immobilized in 100% with 30% of viability decrease. This double effect occurred in 50% of pig'ssperm and 50% of rabbit sperm when the concentration was increased tenfold. The pattern of progressive motility was affected 80% of rat's spermatocytes without agglutination. The values remained the same when the extracts were partially purified with salts of Zn++ and Ba++ or by filtration in a sephadex g-10 column. Analysis with thin layer chromatography of both purified extracts produced 3 compounds in comparison with the ethanolic unpurified extract. The extract of the plant Bursera fagaroides contains 3 compounds, which apparently are glycosides with a potent activity upon agglutination -immobilization and a low effect upon spermatocytes viability, which might be used as contraceptives .</p>","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"21 4","pages":"393-8"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12834543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Oral administration of diphenylhydantoin sodium (DFH-Na or phenytoin) predictably affects the liver and kidney of Sprague Dawley rats]. [口服二苯基苯妥英钠(DFH-Na或苯妥英)可预测地影响Sprague Dawley大鼠的肝脏和肾脏]。
Archivos de investigacion medica Pub Date : 1990-10-01
P Garzón de la Mora, J García-Estrada, A Navarro-Ruíz, S Román-Maldonado, B E Bastidas-Ramírez, M González-Hita, I Navarro-Ruiz
{"title":"[Oral administration of diphenylhydantoin sodium (DFH-Na or phenytoin) predictably affects the liver and kidney of Sprague Dawley rats].","authors":"P Garzón de la Mora,&nbsp;J García-Estrada,&nbsp;A Navarro-Ruíz,&nbsp;S Román-Maldonado,&nbsp;B E Bastidas-Ramírez,&nbsp;M González-Hita,&nbsp;I Navarro-Ruiz","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Phenytoin and its vehicle were orally administered to adult Sprague-Dawley rats during 7, 14 and 30 days at doses of 300 and 450 mg/kg/24 hr., respectively. We found: 1) Increased liver DNA concentration in subgroups of animals treated with 450 mg at 7 (P < 0.02) and 15 days (P < 0.001) Phenytoin serum levels were 19 ug/ml. 2) Increased protein concentration with 300 mg at 7 (P < 0.01) and 15 days (P < 0.001), respectively. 3) Cloudy swelling, vacuolar degeneration, liver sinusoids disappearance and lymphocytic cells infiltrate in subgroups of rats receiving vehicle throughout 6, 14 and 15 days correspondingly. The former lesion was found in all subgroups, except that 450 mg treated animals liver more severely affected. 4) Increased DNA concentration in kidney of subgroups receiving 450 mg/kg throughout 7 (P < 0.05), 15 (P < 0.001) and 30 days (P < 0.001), correspondingly. 5) Increased protein concentration in rats receiving 450 mg during 15 days (P < 0.001) and severely decreased at 30 days period. 6) Cloudy swelling was found in all treated animals subgroups. Seven cellular and tissue lesions were caused by vehicle at 15 and 30 days periods. 450 mg of phenytoin predominantly caused tissue condensation and vacuolar degeneration in kidney cortex. 7) propylene glycol do affect liver and kidney at doses below TD-50. Phenytoin stimulate kidney and liver cell proliferation. Caution should be observed when using parenteral phenytoin.</p>","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"21 4","pages":"339-47"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12834637","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Acid hydrolysis of urinary oligosaccharides in type I glycogenosis]. [I型糖原病尿寡糖的酸水解]。
Archivos de investigacion medica Pub Date : 1990-10-01
J Sánchez-Corona, H A Mora-García, O Contreras-Sánchez
{"title":"[Acid hydrolysis of urinary oligosaccharides in type I glycogenosis].","authors":"J Sánchez-Corona,&nbsp;H A Mora-García,&nbsp;O Contreras-Sánchez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Oligosaccharides were isolated by thin layer chromatography from the urine of a patient diagnosed upon clinical and laboratory characteristics as glycogenosis Ia. The oligosaccharides were hydrolyzed with H2SO2 0.5 M at 100 degrees C. The hydrolysis was interrupted at 5, 10 and 20 minutes by the neutralization of the pH at standard temperature. Chromatography of the product of hydrolysis was performed and alpha 1-4 bonds were identified with the addition of ADP developer. The final product of the whole hydrolysis of all the oligosaccharides was glucose.</p>","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"21 4","pages":"349-51"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12834641","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Elimination of epimural microflora from guinea pig cecal epithelium by antimicrobial drugs. 抗菌药物消除豚鼠盲肠上皮的硬膜外菌群。
Archivos de investigacion medica Pub Date : 1990-10-01
J Mora-Galindo, A González-Robles, P Díaz-Esquivel, M Raygoza-Anaya
{"title":"Elimination of epimural microflora from guinea pig cecal epithelium by antimicrobial drugs.","authors":"J Mora-Galindo,&nbsp;A González-Robles,&nbsp;P Díaz-Esquivel,&nbsp;M Raygoza-Anaya","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The effect of antimicrobial drugs on epimural bacteria of guinea pig cecum was assessed by scanning electron microscopy. Metronidazole (500 hg/ml), neomycin (50 hg/ml) or both combined were given orally in drinking water ad libitum for five consecutive days, and representative fragments of cecum were processed for analysis. In untreated animals large areas of mucosa were lined by spiral-shaped bacteria were eliminated by treatment with neomycin, only remaining fusiform bacteria at openings of crypts. metronidazole was effective for eliminating all bacterial populations; the same effect was achieved with a combination of neomycin and metronidazole, rendering the cecum free of epimural bacteria, the health of guinea pig was unaffected by these treatments. The cecal epithelium of antimicrobial-treated animals can be used for experimental studies without interference of epimural bacteria.</p>","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"21 4","pages":"389-92"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12834455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A rapid method for ovulation detection. 一种快速检测排卵的方法。
Archivos de investigacion medica Pub Date : 1990-10-01
A Carranco-López, R Reyes, L Huacuja, N M Delgado
{"title":"A rapid method for ovulation detection.","authors":"A Carranco-López,&nbsp;R Reyes,&nbsp;L Huacuja,&nbsp;N M Delgado","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Uronic acid (UA) content in whole urine showed a characteristic pattern of fluctuations during menstrual cycle (24 cycles) with a distinct peak on the day of ovulation (midcycle peak 1043 + 68 micrograms/ml urine. This peak of maximal UA concentration was validated by ultrasonography (abdominal and/or vaginal scanner and basal body temperature. In hormonal induced menstrual cycle (5 cycles) a significant decrease in Ua concentrations were observed during the follicular phase (20%) and in the midcycle peak (11%) when they were compared with the same values in the normal cycle. Nevertheless, two days after the ovulation peak occurs a second peak can be observed (1344 + 799 micrograms UA/ml urine). On the other hand in the anovulatory cycles (5 cycles) the same diminishing behavior in the UA concentrations were observed in both phases of the cycle (50-60%) with the expected lack of the midcycle peak. Results that clearly show that UA excretion in urine reflect a excellent correlation with the menstrual cycle allowing us to propose this technique as an accurate and reliable method to detect ovulation.</p>","PeriodicalId":75554,"journal":{"name":"Archivos de investigacion medica","volume":"21 4","pages":"289-92"},"PeriodicalIF":0.0,"publicationDate":"1990-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"12834697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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