{"title":"[Amyloidosis: definition and classification].","authors":"H Adle-Biassette, A V Vallat, D Nochy","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Amyloidoses are diseases characterized by deposits of altered proteins in the tissues. The amyloid deposit is always extracellular and presents a fibrillary conformation. 85% of the amyloid protein is constituted of a specific protein of each variety of amyloidosis, while the other 15% consists of other proteins and glycoproteins common to all types of amyloidosis. The same amyloid protein can be associated with various clinical forms and, inversely, different proteins can give the same clinical expression. It is therefore preferable to adopt a biochemical classification of amyloidosis. This classification is based on the identification of the various amyloid proteins by immunohistochemical analysis. About fifteen different amyloid proteins have already been identified. Hereditary amyloidoses are the most heterogeneous forms and amyloidoses of the nervous system are still under investigation. Immunohistochemical analysis of the majority of amyloidoses (represented by amyloidosis AA and AL) can now be performed routinely on tissue samples.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"44 2-3","pages":"101-5"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19765252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Doctor Anglas' observations on the presence of cytomegalic cells in macerated fetal tissues].","authors":"P Diosi","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Early in this century, Anglas had observed in the renal tubules of a macerated fetus unusual giant structures, which turned out to be cytomegalic inclusion cells. But since he omitted to distinguish them by a suggestive term from previously known giant cells, his observation felt into oblivion. Yet, it constituted the first report on the occurrence of cytomegaly in France, and in general, the first indication of the histogenic origin of these cells, as well as of their resistance to autolysis.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"44 4","pages":"188-92"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20103849","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C Mainguené, D Hugol, P Hofman, N Clement, J C Boiselle, C Huguet, P Poitout
{"title":"[Adenomatoid tumors of the uterus. Study of 5 cases with immunohistochemical and ultrastructural confirmation of the mesothelial origin].","authors":"C Mainguené, D Hugol, P Hofman, N Clement, J C Boiselle, C Huguet, P Poitout","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Five cases of adenomatoid tumors of the uterus (ATU) are reported. These benign lesions are discovered in 1% of the hysterectomy specimens, performed on 20- to 85-years-old women. Their frequency is certainly underestimated, since ATU have the same macroscopic appearance as leiomyomas. Histologically, ATU are formed by gland-like and pseudovascular lumens, lined by regular, cuboidal or flattened cells, and surrounded by hyperplastic smooth muscle bundles. Immunohistochemical coexpression of cytokeratin and vimentin confirms with a mesothelial histogenesis. The ultrastructural study, showing luminal microvilli and desmosomes supports the hamartomatous development of ATU, corresponding to mesothelial inclusions from the peritoneum into the myometrium. Some giant or diffuse ATU, which are clinically disturbing, are differentiated from carcinomatous or vascular proliferations by frozen section examination. The treatment is made by surgical excision.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"44 4","pages":"174-9"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20103973","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
D Daskalopoulou, D Tamiolakis, S Tsousis, N Apostolikas, S Markidou
{"title":"Sources of discrepancies in the diagnosis of Hodgkin's disease by fine needle aspiration.","authors":"D Daskalopoulou, D Tamiolakis, S Tsousis, N Apostolikas, S Markidou","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The aim of this study was to assess the value of Fine Needle Aspiration (FNA) Cytology in the diagnosis of Hodgkin's Disease (HD) and to identify the sources and nature of the inaccuracies related to this procedure. We retrospectively studied all cases cytologically diagnosed in our laboratory as HD during a five year period (1990-1994). We also traced cases in which FNA cytology failed to reveal HD and where a subsequent HD diagnosis was made by histology. Of the 99 cases studied, a histological report was available for 93. In 82 cases FNA was carried out as part of the initial evaluation. In the remaining 17 cases the diagnosis of HD was known and FNA was performed in order to confirm or exclude a relapse. The results included 4 false positive for HD, 5 false negative and 3 HD-suspicious cases (only one of which proved histologically to be HD while the remaining two were other neoplasms). The re-evaluation of the last 12 cases identified 3 different sources of error: a) Material adequacy criteria; b) Sampling techniques; c) Interpretation.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"44 4","pages":"166-73"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20103972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
H Adle-Biassette, B Marc, N Benhaiem-Sigaux, M Durigon, F Gray
{"title":"[Cerebral infarctions in a drug addict inhaling heroin].","authors":"H Adle-Biassette, B Marc, N Benhaiem-Sigaux, M Durigon, F Gray","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Cerebral infarcts complicating heroin abuse have been seldom reported and only clinically and radiologically documented. We report a pathological case of cerebral infarct in a heroin sniffer. A 31 year old, male, heroin sniffing addict for several years, with no known past neurological history, was found dead one morning. The evening before, he had presented the usual signs of recent heroin intake. Opiates were found in large amounts in blood and urine. Post mortem HIV serology was negative. Post mortem examination revealed the usual signs of heroin addiction, but no cutaneous signs of IV drug use. Myocardial ischemic lesions of various ages involved the anterolateral part of the left ventricle; coronary arteries were normal. Neuropathological study revealed, partly cystic infarcts involving both cerebral hemispheres. They were mostly cortical with an intralaminar pattern and a watershed distribution at the boundaries between the territories of the anterior and middle cerebral arteries and the middle posterior cerebral arteries. Intracerebral vessels, large intracranial and cervical arteries were normal.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"44 1","pages":"12-7"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19735899","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Renal clear cell carcinoma in children].","authors":"I Brochériou, V Martin-Pop, A Vieillefond","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The authors report a case of renal clear cell carcinoma in a 12-year-old boy. This variety of carcinoma, rare in childhood, differs from Wilms' tumor in the later age of presentation, different symptoms at presentation, and a worse prognosis.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"44 1","pages":"34-6"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19735902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
E Pereda, C Ereño, A Fernández-Larrinoa, A Uliarte, J I Lòpez
{"title":"Small intestinal stromal tumour with skeinoid fibers. Immunohistochemical study of two cases with CD 34 expression.","authors":"E Pereda, C Ereño, A Fernández-Larrinoa, A Uliarte, J I Lòpez","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The presence of the so-called \"skeinoid fibers\" in stromal tumours of the gastrointestinal tract is a rare event. The exact origin of this puzzling group of neoplasms still remains controversial. Despite all, the recognition of this histologic feature in routine practice is important for its presence seems to carry histogenetic implications. The authors report the histopathologic findings of two of such cases both occurring in the jejunum of a male aged 48 and a woman, 64. Their positivity with CD 34 antigen is enhanced, for this peculiar immunophenotype help to distinguish them from other stromal tumors in the small bowel. Additionally, the literature is reviewed and commented.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"44 2-3","pages":"125-8"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19765258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Coupling of Perls and Sirius-Red stainings in hepatic puncture-biopsy].","authors":"C Sattonnet, M J Castellani, D Ouzan","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The association of two standard stains (Perls and Sirius-Red) can be useful in the hepatic biopsy interpretation, particularly for iron localization. This simple technique is used successfully in our laboratory. It may also permit to avoid the paraffin inclusion block.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"44 2-3","pages":"129-31"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"19765259","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
J Van Dorpe, F De Weer, J Bekaert, J Lauweryns, P Moerman
{"title":"Malignant myoepithelioma of the breast. Case report with immunohistochemical study.","authors":"J Van Dorpe, F De Weer, J Bekaert, J Lauweryns, P Moerman","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Malignant myoepitheliomas of the breast are rare. We report a case of spindle cell malignant myoepithelioma studied by light microscopy and immunohistochemistry. The malignant myoepithelial cells stained positively for cytokeratins, smooth muscle actin and vimentin, but not for epithelial membrane antigen. The tumor showed a focal positivity for S100 protein. A short review of the morphology and immunohistochemistry of cases reported in the international literature is given in a table. Morphologically malignant myoepitheliomas can be subdivided into spindle cell malignant myoepitheliomas and malignant adenomyoepitheliomas.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"44 4","pages":"193-8"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20103850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"[Invasive papillary and pseudopapillary (micropapillary) carcinoma of breast].","authors":"A Gentile, V Becette","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Classical invasive papillary carcinoma of the breast, is rare. In their pure form, they constitute 1.5% of all invasive breast carcinomas. Only one study clearly distinguishes them from intra-ductal papillary carcinomas; in this study they display a low metastatic potential and a relatively good prognosis. Lately, a new type of papillary carcinoma has been described which is characterized by inversion of the tumor cell polarity and papillations devoid of fibrovascular cores. Described by several authors by the term \"micropapillary\" carcinoma, the originally suggested term \"pseudo-papillary\" seems to be more appropriate; moreover, this designation would more clearly distinguish them from papillary carcinomas from which they clearly differ by their behavior. Furthermore, the pseudo-papillary carcinomas present an important lymphotropism, the effect of which on their clinical course is not yet clear. Further studies are necessary to determine whether these tumors, more frequent than classical papillary carcinomas, should be considered as a distinct clinical entity.</p>","PeriodicalId":75531,"journal":{"name":"Archives d'anatomie et de cytologie pathologiques","volume":"44 5-6","pages":"225-30"},"PeriodicalIF":0.0,"publicationDate":"1996-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"20270593","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}