Annales de medecine interne最新文献

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Methadone treatment in Ontario after the 1996 regulation reforms. Results of a physician survey. 1996年安大略省美沙酮治疗法规改革后。医生调查的结果。
Annales de medecine interne Pub Date : 2002-11-01
Benedikt Fischer, Deanna Cape, Natalie Daniel, Louis Gliksman
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引用次数: 0
[Immunity, autoimmunity, and the aging process: complex interactions]. [免疫、自身免疫和衰老过程:复杂的相互作用]。
Annales de medecine interne Pub Date : 2002-11-01
Robert Moulias, Agathe Raynaud-Simon, Sophie Moulias, Sylvie Meaume
{"title":"[Immunity, autoimmunity, and the aging process: complex interactions].","authors":"Robert Moulias,&nbsp;Agathe Raynaud-Simon,&nbsp;Sophie Moulias,&nbsp;Sylvie Meaume","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Immune deficiency is not an age-related process, but rather a progressive process where predominantly cellular immune response is gradually, but never totally, replaced by antibody response. Cellular immune response appears to be associated with the intrinsic mechanisms of pathological aging. Cellular immunity resulting from induction of macrophage stimulation and cytokine secretion appears to involved. These immuno-inflammatory changes mimic the effects of pathological aging in the different organs. Are they essential factors or simply accessory phenomena? Switching towards an antibody response appears to be a mechanism of adaptation rather than a mechanism of deterioration. Immune status provides a good means of assessing general status in an elderly subject. An attempt should be made to identify the cause of any immune deficiency since age is not in itself an underlying cause. Etiological treatment is indicated.</p>","PeriodicalId":75505,"journal":{"name":"Annales de medecine interne","volume":"153 7","pages":"441-5"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22257235","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Vitamin B12 deficiency-induced moderate hyperhomocysteinemia and venous thromboembolism]. [维生素B12缺乏引起的中度高同型半胱氨酸血症和静脉血栓栓塞]。
Annales de medecine interne Pub Date : 2002-11-01
Emmanuel Andres, Anne-Elisabeth Perrin, Esther Noel, Jean-Louis Schlienger, Jean-Frédéric Blickle, Jean-Marie Brogard
{"title":"[Vitamin B12 deficiency-induced moderate hyperhomocysteinemia and venous thromboembolism].","authors":"Emmanuel Andres,&nbsp;Anne-Elisabeth Perrin,&nbsp;Esther Noel,&nbsp;Jean-Louis Schlienger,&nbsp;Jean-Frédéric Blickle,&nbsp;Jean-Marie Brogard","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75505,"journal":{"name":"Annales de medecine interne","volume":"153 7","pages":"483-4"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22256546","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Informing the hepatitis C diagnosis and the liver biopsy decision. A painful case]. [告知丙型肝炎诊断和肝活检决定。][痛苦的案例]。
Annales de medecine interne Pub Date : 2002-11-01
Michel Ruel
{"title":"[Informing the hepatitis C diagnosis and the liver biopsy decision. A painful case].","authors":"Michel Ruel","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75505,"journal":{"name":"Annales de medecine interne","volume":"153 7 Suppl","pages":"2S45-6"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22187607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Nutrition and immunity in the elderly]. 【老年人的营养与免疫】。
Annales de medecine interne Pub Date : 2002-11-01
Sophie Moulias
{"title":"[Nutrition and immunity in the elderly].","authors":"Sophie Moulias","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Global malnutrition (reduced intake or increased requirements for protein and calories) is the most common nutritional deficit in the elderly population. Micronutrients (vitamins and trace minerals) deficiencies are also common in older adults. Malnutrition consequences on immunity are characterized by a decrease in cell mediation immunity with a reduction in naive T cells and in cytokine production. During infection, the treatment must be specific and after infection it has to associate nutritional supplementation and exercise. The lack of clear benefit in the use of specific micronutrient should discourage the use of high-dose supplementation for an immunologic indication.</p>","PeriodicalId":75505,"journal":{"name":"Annales de medecine interne","volume":"153 7","pages":"446-9"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22257236","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Biermer's anemia corrected by oral vitamin B12]. [口服维生素B12治疗比尔默氏贫血]。
Annales de medecine interne Pub Date : 2002-11-01
Georges Kaltenbach, Emmanuel Andres, Marie Noblet-Dick, Jean-Louis Schlienger
{"title":"[Biermer's anemia corrected by oral vitamin B12].","authors":"Georges Kaltenbach,&nbsp;Emmanuel Andres,&nbsp;Marie Noblet-Dick,&nbsp;Jean-Louis Schlienger","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75505,"journal":{"name":"Annales de medecine interne","volume":"153 7","pages":"485-6"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22256547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Monoclonal gammopathy of undetermined significance]. [意义不明的单克隆γ病]。
Annales de medecine interne Pub Date : 2002-11-01 DOI: 10.32388/ir51hb
P. Chaïbi, L. Merlin, C. Thomas, F. Piette
{"title":"[Monoclonal gammopathy of undetermined significance].","authors":"P. Chaïbi, L. Merlin, C. Thomas, F. Piette","doi":"10.32388/ir51hb","DOIUrl":"https://doi.org/10.32388/ir51hb","url":null,"abstract":"Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic disorder with serum monoclonal immunoglobulin less than 30 g/l. It preferentially affects elderly patients; MGUS prevalence is about 1% in the general population and about 10% in patients aged over 80 years. MGUS diagnosis is based on elimination of other causes of serum monoclonal immunoglobulin, particularly multiple myeloma. Within the 20 years following diagnosis of MGUS, about 25% of patients will evolve towards myeloma or other malignant lymphoproliferative disorder. No factor has been identified to date which can efficiently predict this evolution. Recent data concerning immunophenotype, cytogenetics and molecular biology of plasma cells demonstrate the link between MGUS and multiple myeloma. MGUS clearly appears now as a plasma cell monoclonal pathology with reduced malignity. Soon, new biological data would help to discriminate patients with MGUS who will remain asymptomatic life-long from those who will evolve towards malignant lymphoproliferative disorder.","PeriodicalId":75505,"journal":{"name":"Annales de medecine interne","volume":"153 7 1","pages":"459-66"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69632394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
[Bupropion: risks and advantages of its use. What preclinical research says]. 安非他酮:使用的风险与优势。临床前研究的结果]。
Annales de medecine interne Pub Date : 2002-11-01
Florence Noble
{"title":"[Bupropion: risks and advantages of its use. What preclinical research says].","authors":"Florence Noble","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>There is evidence that nicotine, the major constituent of cigarette smoking, leads to addiction. Although a high percent of smokers express the desire to quit, only a small percentage of them are successful in achieving sustained abstinence. Until recently, pharmacological options for treatment of tobacco dependence were primarily limited to the various nicotine replacement therapies. Bupropion provides clinicians and patients with a new non-nicotine alternative. The mechanisms by which bupropion acts as an aid in smoking cessation are unknown. This article is a review of the few explanations taken from the literature, to answer questions about the potential risks of the use of this atypical antidepressant.</p>","PeriodicalId":75505,"journal":{"name":"Annales de medecine interne","volume":"153 7 Suppl","pages":"2S37-41"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22187605","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Treatment of hepatitis C. Paris 27-28 February 2002]. [治疗丙型肝炎,巴黎,2002年2月27-28日]。
Annales de medecine interne Pub Date : 2002-11-01
{"title":"[Treatment of hepatitis C. Paris 27-28 February 2002].","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":75505,"journal":{"name":"Annales de medecine interne","volume":"153 7","pages":"467-77"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22256543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
[Monoclonal gammopathy of undetermined significance]. [意义不明的单克隆γ病]。
Annales de medecine interne Pub Date : 2002-11-01
Pascal Chaïbi, Laurence Merlin, Caroline Thomas, François Piette
{"title":"[Monoclonal gammopathy of undetermined significance].","authors":"Pascal Chaïbi,&nbsp;Laurence Merlin,&nbsp;Caroline Thomas,&nbsp;François Piette","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Monoclonal gammopathy of undetermined significance (MGUS) is an asymptomatic disorder with serum monoclonal immunoglobulin less than 30 g/l. It preferentially affects elderly patients; MGUS prevalence is about 1% in the general population and about 10% in patients aged over 80 years. MGUS diagnosis is based on elimination of other causes of serum monoclonal immunoglobulin, particularly multiple myeloma. Within the 20 years following diagnosis of MGUS, about 25% of patients will evolve towards myeloma or other malignant lymphoproliferative disorder. No factor has been identified to date which can efficiently predict this evolution. Recent data concerning immunophenotype, cytogenetics and molecular biology of plasma cells demonstrate the link between MGUS and multiple myeloma. MGUS clearly appears now as a plasma cell monoclonal pathology with reduced malignity. Soon, new biological data would help to discriminate patients with MGUS who will remain asymptomatic life-long from those who will evolve towards malignant lymphoproliferative disorder.</p>","PeriodicalId":75505,"journal":{"name":"Annales de medecine interne","volume":"153 7","pages":"459-66"},"PeriodicalIF":0.0,"publicationDate":"2002-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"22256542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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